1. COMPROMISO PULMONAR EN ARTRITIS REUMATOIDEA Miércoles 23 de Junio 2010 Julián Vega Adauy , Residente Medicina Interna Universidad de Concepción PRESENTACION FINAL ROTACION REUMATOLOGIA
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9. HIPERTENSIÓN PULMONAR 2ria EPD PRIMARIA (ASOCIADA) ETE crónica ENFERMEDAD TEJ CONECTIVO K. Fagan. Progress in Cardiovascular Diseases 2002
13. — INTRODUCCION K Brown. Proceedings ATS. 2007 IMPORTANCIA DEL COMPROMISO EXT-ART Claro impacto en mortalidad
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16. — ANTECEDENTES HISTÓRICOS DEL PULMÓN REUMATOIDEO Ellman, BMJ. 1948 Relación entre casos de AR con compromiso pulmonar difuso Caplan, thorax. 1953 Neumoconiosis asociada a AR en trabajadores del carbón Patrón nodular particular, distinto al de la llamada Fibrosis pulmonar masiva 1954, fueron reportados Nódulos pulmonares en ausencia de Neumoconiosis Sinclair. Q J Med. 1955 Alta frecuencia de compromiso pleural en AR Cudkowicz Br J Dis Chest 1961 Describió primeras biopsias y estudios de Fx pulmonar en AR + Compromiso pulmonar
72. D’ Alonzo GE. Ann Int Med. 1991 HAP, HISTORIA NATURAL
73. ACCF/AHA Expert Consensus Document on Pulmonary Hypertension. J. Am. Coll. Cardiol. 2009 HAP, SOBREVIDA SEGÚN ETIOLOGIA
74. ACCF/AHA Expert Consensus Document on Pulmonary Hypertension. J. Am. Coll. Cardiol. 2009 HAP, SOBREVIDA SEGÚN ETIOLOGIA HAP asociada a CTD es uno de los grupos con peor sobrevida
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78. UpToDate 18.3. 2010 Obstrucción vía a 2 COMPROMISO VIA a2 BAJA HiperRx. Ha sido controversial Cofounders TABACO + EPD: 60% Ajustado: 20% Etiología Multifactorial RP: Like-Asma
Unique pleural fluid findings in RA. Triad of comet cells, giant cells and background of granular material. Seen in as many as 80% of pleural specimens and are considered unique to RA. These findings are the result of the exfoliation of pleural components from regions of granulomatous pleuritis. The RA cell (or ragocyte) is a leukocyte with small cytoplasmic lipid inclusions containing RF. These may also be seen in TB.
Caplan A. Certain radiological appearances in the chest of coal-miners suffering from rheumatoid arthritis. Torax 1953;8:29-37.
Caplan A. Certain radiological appearances in the chest of coal-miners suffering from rheumatoid arthritis. Torax 1953;8:29-37.
Caplan A. Certain radiological appearances in the chest of coal-miners suffering from rheumatoid arthritis. Torax 1953;8:29-37.
Caplan A. Certain radiological appearances in the chest of coal-miners suffering from rheumatoid arthritis. Torax 1953;8:29-37.
Caplan A. Certain radiological appearances in the chest of coal-miners suffering from rheumatoid arthritis. Torax 1953;8:29-37.
Caplan A. Certain radiological appearances in the chest of coal-miners suffering from rheumatoid arthritis. Torax 1953;8:29-37.
Comparison of the Kaplan-Meier survival curves between the subject groups and the UIP pattern associated with rheumatoid arthritis (RA-UIP). CVD-NSIP = nonspecific interstitial pneumonia associated with collagen vascular diseases; I-NSIP = idiopathic nonspecific interstitial pneumonia; IPF/UIP = idiopathic pulmonary fibrosis/usual interstitial pneumonia; non–RA-UIP = usual interstitial pneumonia in the patients with non–rheumatoid arthritis–collagen vascular diseases. The statistical significances between groups were as follows: RA-UIP versus non–RA-UIP, p = 0.015; RA-UIP versus CVD-NSIP, p = 0.043; RA-UIP versus I-NSIP, not significant; RA-UIP versus IPF/UIP, not significant. Reprinted by permission from Reference Park JH, Kim DS, Park IN, Jang SJ, Kitaichi M, Nicholson AG, Colby TV. Prognosis of fibrotic interstitial pneumonia: idiopathic versus collagen vascular disease-related subtypes. Am J Respir Crit Care Med 2007;175:705–711
Grupo 1: EPD + tos seca + disnea Grupo 2: Alteraciones no EPD Grupo 3: Sin EPD
Grupo 1: EPD + tos seca + disnea Grupo 2: Alteraciones no EPD Grupo 3: Sin EPD
Table 2. Most Frequent Pulmonary Abnormalities Detected with High-resolution Computed Tomography Patterns in Rheumatoid Arthritis
Grupo 1: EPD + tos seca + disnea Grupo 2: Alteraciones no EPD Grupo 3: Sin EPD
Most Frequent High-resolution Computed Tomography Patterns in Rheumatoid Arthritis Associated Interstitial Lung Disease (ILD)
Most Frequent High-resolution Computed Tomography Patterns in Rheumatoid Arthritis Associated Interstitial Lung Disease (ILD)
Most Frequent High-resolution Computed Tomography Patterns in Rheumatoid Arthritis Associated Interstitial Lung Disease (ILD)
1. Zisman D A, McCune W J, Tino G, Lynch J P I. Drug-induced pneumonitis: the role of methotrexate. Sarcoidosis Vasc Diffuse Lung Dis 2001; 18: 243-2522. Dai M S, Ho C L, Chen Y C, Kao W Y, Chao T Y. Acute respiratory distress syndrome following intrathecal methotrexate administration: a case report and review of literature. Annals of Hematology 2000; 79: 696-6993. Imokawa S, Colby T V, Leslie K O, Helmers R A. Methotrexate pneumonitis: review of the literature and histopathological findings in nine patients. Eur Respir J 2000; 15: 373-3814. McKenna K E, Burrows D. Pulmonary toxicity in a patient with psoriasis receiving methotrexate therapy. Clin Exp Dermatol 2000; 25: 24-275. Sing A, Leitritz L, Roggenkamp A, Kolb H J, Szabados A, Fingerle V, Autenrieth I B, Heesemann J. Pulmonary toxoplasmosis in bone marrow transplant recipients: Report of two cases and review. Clin Infect Dis 1999; 29: 429-433 6. Suwa A, Hirakata M, Satoh S, Mimori T, Utsumi K, Inada S. Rheumatoid arthritis associated with methotrexate-induced pneumonitis: Improvement with i.v. cyclophosphamide therapy. Clin Exp Rheumatol 1999; 17: 355-3587. Yoshida S, Onuma K, Akahori K, Sakamoto H, Yamawaki Y, Shoji T, Nakagawa H, Hasegawa H, Amayasu H. Elevated levels of IL-8 in interstitial pneumonia induced by low-dose methotrexate. Journal of Allergy and Clinical Immunology 1999; 103: 952-9548. Zingg K, Grossenbacher M, Conen D, Truninger K. Methotrexat-Pneumonitis. Schweizerische Rundschau Medizinische Praxis 1999; 88: 573-5789. Aaron S D, Dales R E, Pham B. Management of steroid-dependent asthma with methotrexate: a meta-analysis of randomized clinical trials. Respir Med 1998; 92: 1059-106510. Bartram S A. Experience with methotrexate-associated pneumonitis in northeastern England: comment on the article by Kremer et al. Arthr Rheum 1998; 41: 1327-132811. Camiciottoli G, Trapani S, Castellani W, Ginanni R, Ermini M, Falcini F. Effect on lung function of methotrexate and non-steroid anti-inflammatory drugs in children with juvenile rheumatoid arthritis. Rheumatol Int 1998; 18: 11-1612. Cron R Q, Sherry D D, Wallace C A. Methotrexate-induced hypersensitivity pneumonitis in a child with juvenile rheumatoid arthritis. J Pediatr 1998; 132: 901-90213. Hassanein T, Monson P, Chatfield E, DeGuzman L, El Mola T. Hign ANA levels do not preclude interferon therapy in patients with chronic hepatitis C infection. American Journal of Gastroenterology 1998; 93: 167614. Kremer J M. Experience with methotrexate-associated pneumonitis in northeastern England. Arthr Rheum 1998; 41: 1328-132815. Mateo I, Canete C, Nolla J M, Fiter J, Rodriguez Sanchon B, Romero P. Evolution of pulmonary function in rheumatoid arthritis patients taking methotrexate. Br J Rheumatol 1998; 37 (Suppl 1): 11816. Weinblatt M E, Maier A L, Fraser P A, Coblyn J S. 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1. Zisman D A, McCune W J, Tino G, Lynch J P I. Drug-induced pneumonitis: the role of methotrexate. Sarcoidosis Vasc Diffuse Lung Dis 2001; 18: 243-2522. Dai M S, Ho C L, Chen Y C, Kao W Y, Chao T Y. Acute respiratory distress syndrome following intrathecal methotrexate administration: a case report and review of literature. Annals of Hematology 2000; 79: 696-6993. Imokawa S, Colby T V, Leslie K O, Helmers R A. Methotrexate pneumonitis: review of the literature and histopathological findings in nine patients. Eur Respir J 2000; 15: 373-3814. McKenna K E, Burrows D. Pulmonary toxicity in a patient with psoriasis receiving methotrexate therapy. Clin Exp Dermatol 2000; 25: 24-275. Sing A, Leitritz L, Roggenkamp A, Kolb H J, Szabados A, Fingerle V, Autenrieth I B, Heesemann J. Pulmonary toxoplasmosis in bone marrow transplant recipients: Report of two cases and review. Clin Infect Dis 1999; 29: 429-433 6. Suwa A, Hirakata M, Satoh S, Mimori T, Utsumi K, Inada S. 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