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HISTORY
Diphyllobothrium Latum
ANCIENT & MODERN
Earliest infection of tapeworms in general
was found in 2 million year old African pre-
human remains


Earliest infection of D. latum found in
4,000-10,000 year old human remains in
South America, yet few cases are now
reported in South America (mainly in
Europe and Asia)


However, no distinct ‘point’ in time where
D. latum infected humans


In Europe, epidemics traditionally started
with Jewish women tasting uncooked fish
while preparing gefilte fish


Introduced to North America by
Scandinavian immigrants; spread by dogs
that were fed raw fish
TREATMENT
Diphy!obothrium Latum
PHARMACEUTICALS

         Praziquantel- 95% effective,
         preferable

         Niclosamide- slightly less effective,
         with few side effects

         1-2 hours after taking drug, saline
         purge person to flush worms out of
         body

         Both are available in oral tablets,
         and only need to be taken once.
PREVENTION PLANS

Avoid eating raw fish

Proper disposal of human feces; no
dumping of sewage into bodies of
water.

Fish that is brined, completely
cooked, or frozen at -10˚C for 24
hours is free of infection

Prompt treatment of infected humans

Preventing large mammals to gain
access to aquaculture sites (as in
Chile)
DISCUSSION

Often people refuse to take the pharmaceutical drugs and
use herbal remedies (ie: buttermilk with Sprague powder,
lemon juice with black salt, etc) in their place. Since these
remedies lack the 95% effectiveness of medication, how can
these people be convinced to take Praziquantel?

By completely avoiding raw fish, Diphyllobothriasis can be
completely eradicated. So, why not mandate that all fish be
frozen, smoked, or cooked?

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D. latum

  • 1.
  • 3.
  • 4. ANCIENT & MODERN Earliest infection of tapeworms in general was found in 2 million year old African pre- human remains Earliest infection of D. latum found in 4,000-10,000 year old human remains in South America, yet few cases are now reported in South America (mainly in Europe and Asia) However, no distinct ‘point’ in time where D. latum infected humans In Europe, epidemics traditionally started with Jewish women tasting uncooked fish while preparing gefilte fish Introduced to North America by Scandinavian immigrants; spread by dogs that were fed raw fish
  • 5.
  • 7.
  • 8. PHARMACEUTICALS Praziquantel- 95% effective, preferable Niclosamide- slightly less effective, with few side effects 1-2 hours after taking drug, saline purge person to flush worms out of body Both are available in oral tablets, and only need to be taken once.
  • 9.
  • 10. PREVENTION PLANS Avoid eating raw fish Proper disposal of human feces; no dumping of sewage into bodies of water. Fish that is brined, completely cooked, or frozen at -10˚C for 24 hours is free of infection Prompt treatment of infected humans Preventing large mammals to gain access to aquaculture sites (as in Chile)
  • 11.
  • 12. DISCUSSION Often people refuse to take the pharmaceutical drugs and use herbal remedies (ie: buttermilk with Sprague powder, lemon juice with black salt, etc) in their place. Since these remedies lack the 95% effectiveness of medication, how can these people be convinced to take Praziquantel? By completely avoiding raw fish, Diphyllobothriasis can be completely eradicated. So, why not mandate that all fish be frozen, smoked, or cooked?