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OPHTHALMIA
NEONATORUM
Presented By:
Ms. Aakanksha Bajpai
Assistant Professor
Rama University
INTRODUCTION
Ophthalmia Neonatorum is also known as Neonatal
Conjunctivitis, it is a form of conjunctivitis contracted
in newborns during delivery. Baby’s eyes are
contaminated during passage through the birth canal
from a mother infected from either Neisseria Gonorrhea
or Chlamydia trachomatis.
DEFINITION
Ophthalmia Neonatorum is defined as conjunctivitis
which is the inflammation of the surface and conjunctiva.
INCIDENCE
 It affects 1- 12 % of infants in the western world.
 Upto 23% in developing countries.
ETIOLOGY
 The common causative agents are:
i. chlamydia trachomatis
ii. Neisseria gonorrhoea
iii. Herpes Simplex virus-type-II
 Chemical irritation
CLINICAL MANIFESTATIONS
 Eye discharge- watery, mucopurulent in one or both eyes.
 Swollen eyelids
 Conjunctiva shows hyperaemia and chemosis
 Pain & tenderness in the eyeball
DIAGNOSTIC EVALUATION
a) History taking
b) Eye examination
c) Eye discharge for gram staining, culture & sensitivity
MANAGEMENT
MANAGEMENT
N.gonorrhea
Treatment depends on the specific etiology:
 Infant is isolated during the first 24 hours of treatment.
 Eyes are irrigated with sterile isotonic saline every 1- 2
hours until clear.
 Bacitracin eye ointment four times per day.
 If cornea is involved then atropine sulphate ointment
should be applied.
MANAGEMENT
Systemic therapy:
Neonates should be treated for 7 days with one of the
following regimens.
 Ceftriaxone : 75- 100 mg/kg/day IV QID
 Cefotaxime: 100- 150 mg/kg/day IV 12 hourly
 Ciprofloxacin: 10-20 mg/kg/day IV
MANAGEMENT
Chlamydia
 Erythomycin suspension 40 mg/kg daily orally QID for
14 days
 Topical ointment alone is ineffective.
MANAGEMENT
Herpes simplex virus
 infant is isolated.
 Systemic therapy with acyclovir 20 mg/kg every 8
hours for 2 weeks is given IV
 Topical use of 0.1% iododeoxyuridine ointment 5
times a day for 10 days is used.
PROPHYLAXIS
 Clean the eyelids with sterile cotton & saline.
 Separate lids and apply 2 drops or a 1 to 2 cm ribbon of
ointment in each conjunctival sac.
 Massage lids gently to ensure spread of the medication.
 Wipe excess medication from eye with sterile cotton 1
minute after application.
Ophthalmia Neonatorum or Neonatal Conjunctivitis

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Ophthalmia Neonatorum or Neonatal Conjunctivitis

  • 1. OPHTHALMIA NEONATORUM Presented By: Ms. Aakanksha Bajpai Assistant Professor Rama University
  • 2. INTRODUCTION Ophthalmia Neonatorum is also known as Neonatal Conjunctivitis, it is a form of conjunctivitis contracted in newborns during delivery. Baby’s eyes are contaminated during passage through the birth canal from a mother infected from either Neisseria Gonorrhea or Chlamydia trachomatis.
  • 3. DEFINITION Ophthalmia Neonatorum is defined as conjunctivitis which is the inflammation of the surface and conjunctiva.
  • 4. INCIDENCE  It affects 1- 12 % of infants in the western world.  Upto 23% in developing countries.
  • 5. ETIOLOGY  The common causative agents are: i. chlamydia trachomatis ii. Neisseria gonorrhoea iii. Herpes Simplex virus-type-II  Chemical irritation
  • 6. CLINICAL MANIFESTATIONS  Eye discharge- watery, mucopurulent in one or both eyes.  Swollen eyelids  Conjunctiva shows hyperaemia and chemosis  Pain & tenderness in the eyeball
  • 7. DIAGNOSTIC EVALUATION a) History taking b) Eye examination c) Eye discharge for gram staining, culture & sensitivity
  • 9. MANAGEMENT N.gonorrhea Treatment depends on the specific etiology:  Infant is isolated during the first 24 hours of treatment.  Eyes are irrigated with sterile isotonic saline every 1- 2 hours until clear.  Bacitracin eye ointment four times per day.  If cornea is involved then atropine sulphate ointment should be applied.
  • 10. MANAGEMENT Systemic therapy: Neonates should be treated for 7 days with one of the following regimens.  Ceftriaxone : 75- 100 mg/kg/day IV QID  Cefotaxime: 100- 150 mg/kg/day IV 12 hourly  Ciprofloxacin: 10-20 mg/kg/day IV
  • 11. MANAGEMENT Chlamydia  Erythomycin suspension 40 mg/kg daily orally QID for 14 days  Topical ointment alone is ineffective.
  • 12. MANAGEMENT Herpes simplex virus  infant is isolated.  Systemic therapy with acyclovir 20 mg/kg every 8 hours for 2 weeks is given IV  Topical use of 0.1% iododeoxyuridine ointment 5 times a day for 10 days is used.
  • 13. PROPHYLAXIS  Clean the eyelids with sterile cotton & saline.  Separate lids and apply 2 drops or a 1 to 2 cm ribbon of ointment in each conjunctival sac.  Massage lids gently to ensure spread of the medication.  Wipe excess medication from eye with sterile cotton 1 minute after application.