Scenario and Strategic Planning: A Case Study of Eli Lily & Co.
1. Scenario and Strategic Planning
Eli Lilly & Co.
● CHEE LIUNG WUN ● LIM SHIEH CHERN ● NG YEE JIE ●
2. Preface
• Scenario planning is a tool that can be used to
– Explore the impact of different possible futures for
pharmaceutical industry.
– Help to avoid overlooking important opportunities
and major threats
• This can be done by analysing rapid, turbulent
and uncertain shift in the industry environment,
thus the survival of Eli Lilly in the pharmaceutical
industry
4. The Company - Eli Lilly & Co.
4
AboutUs
Global,
research-based
pharmaceutical
company and
one of the
world's largest
corporations.
Origin
Founded in
1876 by a
retired colonel
& Pharmacist,
Eli Lilly. Global
headquarter in
Indianapolis,
United States
Mission
To makes
medicines that
help people live
longer,
healthier, more
active lives
Source : Eli Lilly and Company (www.lilly.com)
5. Eli Lilly & Co.
5
• Today, marketed in 143 countries, 9th largest pharmaceutical company in world.
Steadfastly remained independent, but not isolated. Global headquarters in
Indianapolis, United States
• Global employees’ number approximately 40,000, and its medicines are marketed in
143 countries.
• Major research and development facilities in 8 countries and conducts clinical trials in
more than 50 countries. Source : Eli Lilly and Company (www.lilly.com)
6. Scope and Time Frame
• 7 Years
Duration
• Corporate level, to identify possible challenges
Scope
• To maintain Eli Lilly’s position as one of the top ten
elite multinational pharmaceutical firms globally
Aim
7. Major Stakeholders
• Stakeholders
Internal Stakeholders – Management Team
External Stakeholders – Major suppliers, health care
providers, regulators and consultants into the process
8. Porter’s Five Forces (Current)
Threat of Substitute
Products
LOW
(Low Value, Risk)
Threat of New
Entrants
LOW
(Patent, regulatory
process & Dist
System)
Bargaining Power of
Buyers
LOW
(Insurance companies,
doctors‘& patients’
buying habit)
Bargaining Power of
Suppliers
LOW
(Multiple sources)
Rivalry Among
Competing Firms in
Industry
LOW
(Different niches &
Patent Protection)
9. Porter’s Five Forces (Trend)
Threat of Substitute
Products
MODERATE
(Embryonic Stem Cell,
Alternatives)
Threat of New
Entrants
MODERATE
(Increased Biotech
Firms)
Bargaining Power of
Buyers
MODERATE
(Buyer Consolidate,
government & hospitals
price sensitive)
Bargaining Power of
Suppliers
MODERATE
(Petrochemical cost )
Rivalry Among
Competing Firms in
Industry
HIGH
(Generics more
common, price pressure)
10. Basic Trends
Political
• United States
Political
Landscape
Economy
• Mergers and
Acquisitions
(M&A)
Socio
• Demographic
- Aging
Population
Legal
• Expiring Patents
and Stricter
Regulation
PESTLE
Analysis
11. United States Political Landscape
Fact
• In 2008,
Democrats won
the presidency
election
Before
• Republicans
protected
branded
pharmaceuticals
After
• Democrats
support generic
pharmaceuticals
12. Mergers and Acquisitions (M&A)
Mutual Benefits
Sharing
Resources
Complement on
Product Pipelines
Work towards
blockbuster drugs
Self Benefits
Improve Sales Cut Cost
Increase
Competiveness
13. Mergers and Acquisitions (M&A)
No Name of Company Merger/Acquisition Year
1 Bayer and Schering AG Acquisition 2006
2 Merck KG aA and Serono Acquisition 2006/2007
3 Nycomed and Altana Pharma Acquisition 2006/2007
4 UCB and Schwarz Pharma Acquisition 2007
5 Mitsubishi and Tanabe Merger 2007
6 Schering-Plough and Organon Acquisition 2007/2008
7 AstraZeneca and Medlmmune Acquisition 2007
8 Mylan and Merck Serono Acquisition 2007
9 Eisai and MGI Pharma Acquisition 2007/2008
10 Takeda and Millennium Acquisition 2008
11
Eli Lilly and ImClone Acquisition 2008
12 Daiichi-Sankyo and Ranbaxy Acquisition 2008
13 Pfizer and Wyeth Acquisition 2008
14 Merck and Schering-Plough
(currently on negotiation)
Merger 2009
List of M&A
undertaken
between
2006 - 2009
Source : Report: Mergers and Acquisitions in the Pharmaceuticals Sector, 2009
14. Demographic - Aging Population
The average expenditure for prescription drugs for people age 65 &
above increased 130%, rising from $819 in 1997 to $1,914 in 2004.
Source: Drug Spending Increases More Than 2.5 Times in 8 Years
15. Expiring Patents
15
“Many branded-name drugs lose patent protection will leading
to a WAVE of generic medications entering the market”
(Quoted from Article “Flooded Generic Pipeline Looms as Branded Patents Expire”)
About 183 of branded drugs will go
off patent starting 2009 until 2013
$60 billion worth of drugs are going
off by 2011
18. Emerging Disease
Emerging diseases like
SARS, Bird Flu, Aids & the
recent type A Influenza
H1N1
Roche who own the proprietary
drug, Tamiflu that can treat bird
flu & type A influenza H1N1 took
full advantage of the situation
Threaten human kind in the form of a
global pandemic
Share price of Roche skyrocketed & attracted
popular & media attention to the industry
19. Embryonic Stem Cell Research
• Able to replicate, divide and produce a
variety of specialized cells to repair human
body, cure disease, and alleviate suffering.
Capability
• Able to cure spinal cord injuries, multiple
sclerosis, diabetes, Parkinson's disease,
cancer, Alzheimer's disease, heart disease,
age-related macular degeneration, hundreds
of rare immune system and genetic disorders
Potential
20. Personalized Medicine & Health IT
Personalized Medicine
• Tailored to suit personal diagnostic requirement
• Aimed to prevent certain diseases and to treat illnesses specifically
• Knowing well ahead the conditions and heritage of body will
translate to prevention and lower healthcare bills
Proficient Use of Health Information Technology
• Health IT can create, store, transmit and manage individuals’ health
data to improve health care safety, cost and quality
• In addition, provides security and privacy of personal health
information
• Other technologies include EMR, EHR, PHR, HIE, PBHR, and e-
prescribing
21. Traditional Medicine
Traditional Chinese
Medicine
• TCM accounts for 38%
of medical products
produced in China in
2007 (Mustapha, 2009)
India’s Ayurveda
• 65% of Indian
population in rural areas
use Ayurveda and
medicinal plants to help
to meet their primary
healthcare need
22. Petrochemical Price
• Pharmaceutic
al products
are the
derivatives of
petrochemical
Overview
• World crude
oil prices
fluctuate
Situation
• Affect the
petrochemical
prices and in
turn will result
higher cost
of medicines
Resulted
23. Possible Scenario Variables
• Based on the above table, the two most important variables are
following:
– Political- United States Political Landscapes
– Embryonic Stem Cell Research
• Both scored the highest rating at 25 points.
25. New Revolutionary Transformation
of the Medical Industry
Description
• Embryonic stem cell
treatment becomes a
reality
• Government support
innovative and
branded drug
• Whole medical
industry would
experience an
explosive revolution
• New breakthroughs in
medical treatments
for uncured diseases
Impact
• Pharmaceutical firms
would continue to
invest heavily in R & D
for further new
innovations
• Diversify and undergo
M & A for
biotechnology
companies that are
specialized in
embryonic stem cell
research
26. The Renaissance of the
Pharmaceutical Industry
Description
• No progress in
embryonic stem
cell research
• Government
support innovative
and branded drug
Impact
• Pharmaceutical
firms still continue
to invest heavily in
R & D for further
new innovations
• Eli Lilly innovate
and invent new
drugs for emerging
diseases in order
to gain competitive
edge against the
other competitors
27. New Era of the Medical Industry
Description
• Government support
generics rather than
branded
pharmaceuticals
• Embryonic stem cell
research successfully
proves its
applicability in
medical treatment
• Embryonic stem cell
gains upper hand
over pharmaceutical
Impact
• Pharmaceutical firms
will be facing a
critical moment
• Eli Lilly should
seriously consider
diversifying into
biotechnology in
stem cell or undergo
M&A to stay
competitive in
pharmaceutical
industry
28. Status Quo of the Pharmaceutical
Industry
Description
• No progress in
embryonic stem cell
research
• No support from
government
• Pharmaceutical
industry remains the
same status quo
• Medical treatments
would only be using
old technologies or
the currently available
technologies.
Impact
• Branded and
innovative
pharmaceutical firms
would lose their
market share
• No further investment
in R & D as the ROI is
not attractive
• Eli Lilly needs to
reduce price and join
the price war with
generic drug’s
manufacturer
29. Consistency and Plausibility
• Are the scenarios plausible?
– The constructed scenarios are greatly plausible
– The next political election in five years may bring
change to the existing situation.
– Stem cell research is an emerging industry and the
future is highly anticipated
• Are the scenarios all challenging?
– All constructed scenarios possess a great challenge to
Eil Lily to survive and sustain its position as the top
multinational pharmaceutical firms
• Rate the importance of the scenarios
30. Rate the importance of the
scenarios
Variable Outcome Probability %
Political Government supports branded drugs 60%
Government supports generic drugs 40%
Embryonic Stem Cell Research Applicable 70%
Not applicable 30%
Scenario P(P) P(S) P(P and S) %P(P and S)
New Revolutionary
Transformation of
the Medical
Industry 0.6 0.7 0.42 42%
The Renaissance
of the
Pharmaceutical
Industry 0.6 0.3 0.18 18%
New Era of the
Medical Industry 0.4 0.7 0.28 28%
Status Quo of the
Pharmaceutical
Industry 0.4 0.3 0.12 12%
31. Identify Research Needs
• Identify whether embryonic stem cell research
will post real threat to the pharmaceutical firms
in the next seven year
• Study or know more about the political situation
33. Conclusion
• From scenario matrix unfolded four variables
scenario, Eli Lilly would be able to align basic
trends especially M&A that shape the future
pharmaceutical industry
• The “Explosive” New Revolution Medical Industry
appeared to be the highly rated scenario with the
probability outcome of 42%
• Although scenario planning cannot predict the
definite future, it helps companies to
compensate usual errors in decision-making
(Schoemaker, 1995)
Hinweis der Redaktion
Since scenario planning only depict possible futures and not specific strategies to overcome them, thus it is not inappropriate to also invite external alliances and partners like major suppliers, health care providers, regulators and consultants into the process.
Method like the six thinking hats developed by de Bono (1999) that allow parallel thinking and avoid arguments can be used. Here, the white hat which focus on acquiring information and green hat which focus on creative thinking and putting forward possibilities can be engaged.
The pharmaceutical industry generally has high average profitability especially in the 1980s and 1990s
Buyer power was low as patients did not shop based on price, while doctors chose products with little reason to consider price, as most patients are medically insured with insurance companies
Suppliers power is also low because the inputs tend to be available from multiple sources.
Threat of substitutions is low as substitutes of other types of therapies were not proven and usually offered little value compared to the effective pharmaceuticals
Threat of new entries was also blocked by patents and also the complicated regulatory process for new drug approval plus the difficulty of establishing a formidable sales forces and distribution system
However, with Republicans’ previous policies and its influences in the current congress, it will continue to give generics some hard times.
Improve sales, cut cost and increase competiveness
Few key uncertain trends will shape the landscape of pharmaceutical industry as stated below. Although these key uncertainties are less significant compare to the above basic trends, Eli Lilly cannot ignore the possibilities that could turn real trends in over 5-10 year’s horizon
Most of the time drugs and medicines work on the idea of “one size fits all” which are not so effective. Personalized medicine can be tailored to suit personal diagnostic requirement, to prevent certain diseases and to treat illnesses specifically. With rising cost of healthcare, knowing well ahead the conditions and heritage of your body will translate to prevention and lower the healthcare bills ultimately (Mustapha, 2009).
The health information technology includes electronic medical record (EMR), electronic health record (EHR), personal health record (PHR), health information exchange (HIE), payor-based health record (PBHR), and electronic prescribing (e-prescribing)
The two variables are chosen because they are rated as highest on importance rating scale. Besides that both variables turn out to be a perfect combination as they possessed great challenges to Eli Lilly.
Embryonic stem cell treatments would be complemented with innovative pharmaceuticals. Thus, there will be many new breakthroughs in medical treatments for diseases that were previously impossible to cure.
The scenarios are plausible due to the recent change of political power in US. The next political election in five years may bring change to the existing situation. Stem cell research is an emerging industry and the future is highly anticipated.
Therefore the constructed scenarios are greatly plausible
All constructed scenarios possess a great challenge to Eil Lily to survive and sustain its position as the top multinational pharmaceutical firms.
Current US government had given branded drugs at least 12 years of market exclusivity, apart from patent protection lifespan (The Wall Street Journal, 2009). The government also realizes that by cutting down support for branded drugs, it would halt innovation for pharmaceutical firms to research new medicine to the market. Although the government is trying to cut down the price of branded drugs, they will still continue to support branded drugs manufacturers or pharmaceutical firms as branded drugs manufacturers drive innovation but generic drug manufacturers do not
In Jan 2009, U.S. Food and Drug Administration had approved the first clinical trial using embryonic stem cells in humans as medical treatment. Geron Corp., a California-based biotech company had been granted the permission to implant embryonic stem cells in paraplegic patients who can’t walk.
The National Institutes of Health established a site (http://stemcells.nih.gov) for publics to gain more information about stem cell research.
If the government turns their support to generic drug manufacturer, Eli Lily needs to figure out strategies to stay competitive in the pharmaceutical industry, either by acquiring existing generic drugs manufacturers or reduce the drugs’ price
After generating the “first-generation” scenarios by quantifying alternative outcomes of obvious uncertainties, it is determined that the two main forces driving the pharmaceutical businesses are i) Merger and Acquisition (M & A) and ii) Cost Cutting. It appeared that M & A which would also assist in cost cutting are inevitable in the pharmaceutical industry. Thus, Game Theory is used to analyse M & A and to generate decision scenarios.