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Chemical Processes in the Body
Use up
Oxygen
Glucose
Amino Acids
Water
Nutrients

Produce
Carbon dioxide
Water
Urea
Heat              Water, Mineral salts, Urea, Carbon Dioxide, Heat
Toxic Chemicals
Excretory Organs in Human




Urinary System        Lungs            Skin

                          Why waste products
                          must be excreted out of
                          the body???
                  Liver
2
Location of the Kidney
Kidney Function
• Detoxify blood
• Increase calcium absorption
  – calcitriol
• Stimulate RBC production
  – erythropoietin
• Regulate blood pressure and electrolyte
  balance
  – renin
Structure of the Urinary System
                           •   2 Kidneys
                           •   2 Ureters
                           •   Bladder
                           •   Urethra
The Blood Supply to the
        Kidney
The Urinary System
Filtration system
in the Kidney

                    Filtration
                    Mineral salts
                    Sugar
                    Amino Acids
                    Waste-Urea

                    Reabsorption
                    All Sugar
                    All amino acids
                    Mineral Salts
                    Water
Function of the Kidney
• Filter blood in order to remove cellular
  waste products from the body.
• Maintain chemical composition, pH and
  water level
• At any given time, 20 % of blood is in the
  kidneys. Humans can function with one
  kidney.
• If one ceases to work, the other
  increases in size to handle the workload.
Cellular waste
• urea
  – (a nitrogenous waste produced in the liver from
    the breakdown of protein. It is the main
    component of urine)
• uric acid
  – (usually produced from breakdown of DNA or
    RNA)
• creatinine
  – (waste product of muscle action).
Composition of Chemicals in the Body
 Substance      Blood in renal      Kidney         Urine
                    artery       tubules (filter
                                    system)
  Glucose           2.0               2.0           0
Mineral salts       10.0              10.0         17.0
Amino acids         0.9               0.9           0
  Protein           88.0                0           0
   Urea             0.5               20.0         20.0
RBC & WBC           47%                0%           0
Kidney failure
•   Urinary Tract Infection
•   Kidney Stone
•   Kidney Infection
•   Diabetic Nephropathy
•   Hypertension
•   Glomerulonephritis
•   HIV nephropathy
Kidney Stone
Treatment of Kidney Failure
              -Dialysis-
• ½ of patients with kidney disease eventually
  require dialysis
• Diffuse harmful waste out of body
• Control BP
• Keep safe level of chemicals in body
• If dialysis cannot work, the patient has to
  undergo kidney transplant
Hemodialysis
• 3-4 times a week
• Takes 2-4 hours
• Machine filters
 blood and
 returns it to
 body
Peritoneal Dialysis
• Abdominal lining filters blood
• 3 types
  – Continuous ambulatory
  – Continuous cyclical
  – Intermittent
PMR Form 3 Science Chapter 3 Excretory system
PMR Form 3 Science Chapter 3 Excretory system

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PMR Form 3 Science Chapter 3 Excretory system

  • 1.
  • 2. Chemical Processes in the Body Use up Oxygen Glucose Amino Acids Water Nutrients Produce Carbon dioxide Water Urea Heat Water, Mineral salts, Urea, Carbon Dioxide, Heat Toxic Chemicals
  • 3. Excretory Organs in Human Urinary System Lungs Skin Why waste products must be excreted out of the body??? Liver
  • 4.
  • 5. 2
  • 6.
  • 7.
  • 9. Kidney Function • Detoxify blood • Increase calcium absorption – calcitriol • Stimulate RBC production – erythropoietin • Regulate blood pressure and electrolyte balance – renin
  • 10. Structure of the Urinary System • 2 Kidneys • 2 Ureters • Bladder • Urethra
  • 11. The Blood Supply to the Kidney
  • 12.
  • 13.
  • 14.
  • 16. Filtration system in the Kidney Filtration Mineral salts Sugar Amino Acids Waste-Urea Reabsorption All Sugar All amino acids Mineral Salts Water
  • 17. Function of the Kidney • Filter blood in order to remove cellular waste products from the body. • Maintain chemical composition, pH and water level • At any given time, 20 % of blood is in the kidneys. Humans can function with one kidney. • If one ceases to work, the other increases in size to handle the workload.
  • 18. Cellular waste • urea – (a nitrogenous waste produced in the liver from the breakdown of protein. It is the main component of urine) • uric acid – (usually produced from breakdown of DNA or RNA) • creatinine – (waste product of muscle action).
  • 19. Composition of Chemicals in the Body Substance Blood in renal Kidney Urine artery tubules (filter system) Glucose 2.0 2.0 0 Mineral salts 10.0 10.0 17.0 Amino acids 0.9 0.9 0 Protein 88.0 0 0 Urea 0.5 20.0 20.0 RBC & WBC 47% 0% 0
  • 20. Kidney failure • Urinary Tract Infection • Kidney Stone • Kidney Infection • Diabetic Nephropathy • Hypertension • Glomerulonephritis • HIV nephropathy
  • 22. Treatment of Kidney Failure -Dialysis- • ½ of patients with kidney disease eventually require dialysis • Diffuse harmful waste out of body • Control BP • Keep safe level of chemicals in body • If dialysis cannot work, the patient has to undergo kidney transplant
  • 23. Hemodialysis • 3-4 times a week • Takes 2-4 hours • Machine filters blood and returns it to body
  • 24. Peritoneal Dialysis • Abdominal lining filters blood • 3 types – Continuous ambulatory – Continuous cyclical – Intermittent