Ultraperformance Convergence Chromatography (UPC2)
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The Waters ACQUITY UPC2 System provides the ability to handle chiral and achiral separations with unequalled speed and unparalled confidence. See the potential of UltraPerformance Convergence Chromatography (UPC2).
![®2015WatersCorporation720005351ENMarch2015LM-SIG
[ ULTRAPERFORMANCE CONVERGENCE CHROMATOGRAPHY ]
NO MATTER YOUR APPLICATION NEEDS, THERE’S A UPC2-MS SOLUTION
CONVERGENCE
CHROMATOGRAPHY
gradient capabilities across
widest polarity range
mass spectrometry compatible
compressed liquid CO2
as a
primary mobile phase
reduction in toxic solvent use
cost savings – solvent and time
NORMALPHASE
wide polarity range
simple retention mechanism
separation based on
polar differences
wide choice of stationary phases
wide choice of mobile phases
chiral and achiral separations
REVERSEDPHASE
CONVERGE THE SEPARATION OF A WIDE VARIETY OF COMPOUNDS IN ONE SYSTEM
Reliable, robust,
dependable performance –
from Discovery to QC
INCREASED EFFICIENCY, LESS
SOLVENT, AND LOWER COSTS
FA
STER ANALYS
IS
UP TO
30x
LESS SOLV ENT
UP TO
75x
LOW ER COST
100x
UP TO
YOUR NORMAL-PHASE CHIRAL METHODS
– IN A FRACTION OF THE TIME
AU
0.00
0.30
min
0.00 2.00 4.00 6.00 8.00 10.00 12.00 14.00
AU
0.00
0.10
0.20
0.00 0.12 0.24 0.36 0.48 0.60
NPLC
min
UPC2
Total analysis time:
NPLC
Total analysis time:
9secs
10mins
Bring the latest advancements of UPLC to the world of traditional SFC.
Primary mobile phase – non-toxic compressed CO2.
GCGas Chromatography
LCLiquid Chromatography
CCConvergence Chromatography
THE WORLD’S FIRST CONVERGENCE CHROMATOGRAPHY SYSTEM
The best choice for fast,
robust chiral separations
Achiral chemistries designed to
set up a new standard of performance
REVERSED
PHASE
NORMAL
PHASE
ADSORPTION
CHROMATOGRAPHY
EASEOFUSE
SEPARATION POWER
CONVERGENCE
CHROMATOGRAPHY
Make
sacrificing
separation
power a thing
of the past
POLARS
CAROTENOIDS
LIPIDSUSP METHODS
AGROCHEMICALS
CHIRAL SYNTHESIS
NON-IONIC SURFACTANTS
OLEOS
STEROIDS
CHIRAL PESTICIDES
FOOD ANALYSIS
FAT-SOLUBLE VITAMINS
CHIRAL BIOANALYSIS
BILE ACIDS
NEUTRACEUTICALS
OINTMENTS
POSITIONAL ISOMERS
NORMAL-PHASE
THE EASE OF REVERSED PHASE – THE POWER OF NORMAL PHASE
Break through all your challenges
The ACQUITY UPC2 System provides the ability to
handle chiral and achiral separations with unequalled
speed and unparalled confidence.
UPC2
MS
SINGLE TRIPLE TOF
PHARMACEUTICAL
HEALTH SCIENCES
FOOD & BEVERAGE
ENVIRONMENTAL
CHEMICAL MATERIALS
UPC2 application areas](https://image.slidesharecdn.com/720005351en-160201180753/85/Ultraperformance-Convergence-Chromatography-UPC2-1-320.jpg?cb=1454350552)
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Ultraperformance Convergence Chromatography (UPC2)
- 1. ®2015WatersCorporation720005351ENMarch2015LM-SIG [ ULTRAPERFORMANCE CONVERGENCE CHROMATOGRAPHY ] NO MATTER YOUR APPLICATION NEEDS, THERE’S A UPC2-MS SOLUTION CONVERGENCE CHROMATOGRAPHY gradient capabilities across widest polarity range mass spectrometry compatible compressed liquid CO2 as a primary mobile phase reduction in toxic solvent use cost savings – solvent and time NORMALPHASE wide polarity range simple retention mechanism separation based on polar differences wide choice of stationary phases wide choice of mobile phases chiral and achiral separations REVERSEDPHASE CONVERGE THE SEPARATION OF A WIDE VARIETY OF COMPOUNDS IN ONE SYSTEM Reliable, robust, dependable performance – from Discovery to QC INCREASED EFFICIENCY, LESS SOLVENT, AND LOWER COSTS FA STER ANALYS IS UP TO 30x LESS SOLV ENT UP TO 75x LOW ER COST 100x UP TO YOUR NORMAL-PHASE CHIRAL METHODS – IN A FRACTION OF THE TIME AU 0.00 0.30 min 0.00 2.00 4.00 6.00 8.00 10.00 12.00 14.00 AU 0.00 0.10 0.20 0.00 0.12 0.24 0.36 0.48 0.60 NPLC min UPC2 Total analysis time: NPLC Total analysis time: 9secs 10mins Bring the latest advancements of UPLC to the world of traditional SFC. Primary mobile phase – non-toxic compressed CO2. GCGas Chromatography LCLiquid Chromatography CCConvergence Chromatography THE WORLD’S FIRST CONVERGENCE CHROMATOGRAPHY SYSTEM The best choice for fast, robust chiral separations Achiral chemistries designed to set up a new standard of performance REVERSED PHASE NORMAL PHASE ADSORPTION CHROMATOGRAPHY EASEOFUSE SEPARATION POWER CONVERGENCE CHROMATOGRAPHY Make sacrificing separation power a thing of the past POLARS CAROTENOIDS LIPIDSUSP METHODS AGROCHEMICALS CHIRAL SYNTHESIS NON-IONIC SURFACTANTS OLEOS STEROIDS CHIRAL PESTICIDES FOOD ANALYSIS FAT-SOLUBLE VITAMINS CHIRAL BIOANALYSIS BILE ACIDS NEUTRACEUTICALS OINTMENTS POSITIONAL ISOMERS NORMAL-PHASE THE EASE OF REVERSED PHASE – THE POWER OF NORMAL PHASE Break through all your challenges The ACQUITY UPC2 System provides the ability to handle chiral and achiral separations with unequalled speed and unparalled confidence. UPC2 MS SINGLE TRIPLE TOF PHARMACEUTICAL HEALTH SCIENCES FOOD & BEVERAGE ENVIRONMENTAL CHEMICAL MATERIALS UPC2 application areas