Effort to generate interest in the subject- MBBS / BDS

1. Prof. Dr. Viyatprajna Acharya
CATECHIZE BIOCHEM
(Biochemistry Quiz)

2. General round (Direct & MCQ)
Step ladder question round
Visual round (2)
Chapter specific round
Clinical question round
Rapid Fire Round

3. General round

4. 1
What is the normal level of
Fasting plasma glucose?

5. 2
In DNA, the two strands are held
together by which type of bond?

6. 3
What is the normal A: G ratio?

7. 4
Name an ecto -enzyme.

8. 5
The enzyme deficient in
Galactosaemia is ?
?
?
?
?

9. 6
Which crystals are deposited in the
joints In gout?

10. 7
If enthalpy is the measure of heat
content,
the entropy is the measure of --
--?

11. 8
In a fatty liver, which lipid component
is deposited in liver tissues?

12. 9
Which phospholipid is present in
the lung surfactant?

13. MCQ round

14. 1
The following is true about Glucokinase
a) It is secreted by the Pancreas
b) It has high Km for glucose
c) It is not specific for glucose
d) All its functions can be done by Hexokinase

15. 2
2. All are true about Vitamin E except
a) Rich source is Palm oil
b) Transported by Chylomicrons
c) Isolated from Wheat germ oil
d) Ionone ring with Isoprenoid side chain

16. 3
3. Glucose enters muscle cells mostly
by:
a)simple diffusion
b)facilitated diffusion using a specific
glucose transporter
c) co-transport with sodium
d)active transport

17. 4
4. Pairs of electrons carried in the form,
FADH2 and NADH+H, collectively contain
enough free energy to rephosphorylate :
a) 6 ATP
b) 5 ATP
c) 7ATP
d) 3 ATP

18. 5
Methotrexate is an antagonist of -
(i) Riboflavin
(ii) Folic acid
(iii) Thiamine
(iv) Cobalamine

19. 6
In competitive inhibition,
(i) V max unchanged
(ii) Km unchanged
(iii) V max decreased
(iv) Km decreased

20. 7
In essential pentosuria, urine
contains -
(i) D-Ribose
(ii) D-Xylose
(iii) L-Xylose
(iv) L-Xylulose

21. 8
Fo component of ATP
synthase is inhibited by
(i) Dinitrophenol
(ii) Rotenone
(iii) Cyanide
(iv) Oligomycin

23. Step ladder question round
(If answer with first clue- 20 marks,
2nd clue- 15 marks, 3rd clue-10 marks,
4th clue- 5 marks)

24. 1
(i) I am a tripeptide involved in the
elimination of free radicals
(ii) I am a co-substrate for some enzymes.
(iii) I act as a conjugating agent too.
(iv) Out of my 3 amino acids 2 are
glycine and glutamate

25. 2
(i) I am a vitamin resembling a
carbohydrate
(ii)I am not synthesized in man & higher
primates.
(iii) I am needed for hydroxylation of
lysine and Proline
(iv) Without me, people have bleeding
gums, delayed healing of wounds and
hypochromic microcytic anemia…

26. 3
(i) I am a reducing equivalent present in RBC
(ii) I maintain RBC membrane integrity
(iii) I keep glutathione in reduced state
(iv) I am produced by HMP shunt

27. 4
(i) I am an organelle known as microbody
(ii) My marker enzyme is Catalase
(iii) I am involved in VLCFA metabolism
(iv) I remove unwanted peroxides and free
radicals from the cell.

28. 5
I am a chemical substance formed as an intermediate in
glycolytic pathway only present in RBC.
My level in blood goes up when you
climb up a mountain/ high altitude.
I help in energy economy of RBC.
I help to unload oxygen from haemoglobin to
the tissues

29. 6
I am a heat stable B complex vitamin having
chemical composition pyridine 3- carboxylic acid
I’m synthesised from an amino acid
I can produce transient cutaneous vasodilatation
on parenteral administration
I can lower lipid levels

30. 7
I am a basic amino acid having pI close to
blood pH
I am found in chromosome
I contain an Imidazole group
Infants can’t synthesize me

31. 8
I am a polyunsaturated fatty acid present
in the biomembranes having 20 C atoms
I belong to Omega 6 family
I give rise to substances that can contract
uterus, secrete HCl from stomach and
stimulate bowel function.
I have 4 double bonds

32. What’s the score??

33. Visual round

34. 1
What was this scientist’s achievement? In which year
he received Nobel prize and in which category?

35. 2
Which molecule they discovered? What was the dog’s name shown in the picture?

36. 3
What is this structure? What is its marker enzyme?

37. 4
Identify the structure. Name one inhibitor.

38. 5
What is the typical presentation known as? What is the deficiency?

39. 6
Identify the type of enzymatic inhibition. What happens to
Km and Vmax?

40. 7
Identify the structure. What is its significance?

41. 8
What was the contribution of Yoshinori Ohsumi for
which he was awarded the Nobel prize for
Physiology and medicine in 2016? Where from this
prize is awarded?

43. Who am I???

44. 1

45. 2

46. 3

47. 4

48. 5

49. 6

50. 7

51. 8

53. Chapter specific
round

54. CARBOHYDRATE
What is fructosan?

55. Protein
Who got noble prize for
sequencing insulin?

56. Lipid
What is the significance of DHA?

57. Vitamins
Which vitamin deficiency will lead to
methylmalonic aciduria?

58. Biological oxidation
• What is the mode of inheritance for
OXPHOS diseases (i.e. diseases
pertaining to mitochondrial
enzymes)

59. Enzymes
Which enzyme is most specific for
diagnosing acute pancreatitis?

60. Nucleotide chemistry
What is the nucleoside
formed from hypoxanthine?

61. Minerals
From which part of intestine
iron is absorbed?

62. Clinical question round

63. 1
A 25 year old female was admitted in
causality with severe dehydration and
vomiting. Her Random blood sugar was
found to be 350 mg/dl. Urine acetone-
positive.

64. 2
A premature newborn baby presented with the
H/o profuse bleeding through nose and ears. Lab
reports shows his Prothrombin time was
prolonged and clotting time was delayed. Which
vitamin may be deficient?

65. 3
A young patient presented with chest
pain. Lab report shows his blood
cholesterol was 350mg/dl. His father’s
report also revealed cholesterol at 400
mg/dl.

66. 4
A child came with lesions at the angle of the
mouth, refusing to feed. From the history he
was found to be under-nourished. Which
vitamin supplementation may help the child?

67. 5
A 60 year old man presented at Orthopaedics clinic with
severe low back ache. He gave history of repeated
respiratory infections. On his urinary investigation
presence of Bence Jone’s protein was found. Serum
protein electrophoresis was ordered to confirm the
diagnosis. What can be the probable diagnosis?

68. 6
A person suffering from malaria took
Primaquin and was brought to the
hospital with severe haemolytic
crisis. What can be the probable
enzymatic defect ?

69. 7
A girl came with complains of blurred vision
after the onset of evening. On examination a
triangular silvery-white spot was found on
the lateral side of the cornea. Which vitamin
supplementation may help the girl?

70. 8
Following a meal of skimmed milk and yogurt,
an adult female patient experiences bloating,
nausea, cramping and pain in the abdomen
followed by watery diarrhoea. This set of
symptoms is observed each time she
consumes such a meal. What can be the
probable diagnosis?

71. Round
Rapid Fire Round

72. 1
01. Mannose supplies energy to the sperm in the
Seminal fluid – T / F?
02. HDL-C has the highest amount of protein – T / F?
03. Normal blood urea level is 250-400 mg/dl – T / F?
04. Primary structure of protein has
sulfide bridges ……T/ F
05. Allopurinol action is an example of suicide
inhibition – T / F?

73. 2
01. Aspartate is an aromatic amino acid – T /
F?
02. SnRNA s are rich in Uracil – T / F?
03. Keratan sulfate doesn’t contain uronic
acid – T / F?
04. Post- prandial lipaemia is due to
LDL-C in blood – T / F?
05. In liver ammonia is converted to
glutamine – T / F?

74. 3
01. In AMI, LDH-5 rises first in blood ….T/ F
02. Which is not a serine protease out of
the following…(i) Pepsin (ii) Trypsin
(iii) Chymotrypsin (iv) Clotting factors
03. Xanthoproteic test is used to detect Arginine
– T / F?
04. Homocystinuria can be caused by folate
deficiency – T / F?
05. Aconitase enzyme is inhibited by fluoride
in Glycolysis – T / F?

75. 4
01. 47 carbon atoms are there
in cholesterol – T / F
02. Urine Ferric chloride test is done to
screen Phenylketonuria – T / F?
03. Linolenic acid belongs to ω3 FA – T / F?
04. Who named the fluid mosaic
model of cell membrane?
05. “A”- DNA is abundantly
seen in nature – T / F?

76. 5
01. Xeroderma pigmentosa is due to lack
of DNA repair – T / F?
02. Zinc is deficient in Wilson’s disease?
03. Galactose is the epimer of glucose
at Carbon 2 – T / F?
04. What is the normal blood level of
SGPT enzyme?
05. Selenocysteine is formed from Serine

77. 6
1. Leucine amino acid is purely
ketogenic – T / F?
02. Normal level of serum calcium is ……
03. CRP is an acute phase protein – T / F?
04. Catalase acts an antioxidant enzyme – T /
F?
05. First pyrimidine to be synthesised by de
novo synthesis is IMP – T / F?

78. 7
01. Adocobalamine is the injectable form of Vit B12
– T / F?
02. A DNA primer is needed for RNA synthesis
…………. T / F?
03. 2.5 ATPs are generated per NADH molecule – T /
F?
04. CPS I is the regulatory enzyme for urea synthesis
– T / F?
05. q & p are denoted for long and short arm of
chromosomes respectively – T / F?

79. For more ppt on Biochemistry for
MBBS and BDS
Please visit my website:
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