SlideShare ist ein Scribd-Unternehmen logo
1 von 16
Presented By : Lodha Sakshi Mahendra
Roll no : 31
Class : T.Y B.Pharmacy
Assig. Topic : Types of capsules
Guided by : Mrs. N.S.Baste Mam
SNJB’S SSDJ COLLEGE OF PHARMACY ,
CHANDWAD.
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 1
TYPES OF CAPSULE :-
1. Hard Gelatin Capsule
2. Soft Gelatin Capsule
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik)
CAPSULESđź’Š
Hard capsules
Soft Capsules
1. HARD GELATIN CAPSULES :-
• The hard gelatin capsule consists of two pieces in the
form of cylinders closed at one end.
• The shorter piece is called the cap. This cap fits over the
open end of longer piece called body.
• Hard gelatin capsules are also known as dry-filled
capsules or two piece capsules.
• This capsules are used in extemporaneous
compounding of Rx.
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 3
• This capsules are made up of gelatin , sugar and water.
• HGC are tasteless.
• Colour with various FD & C and D & C dyes.
• They made opaque by addition of Titanium Dioxide.
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 4
•Manufacturing of Hard gelatin capsules :-
Steps involved in making empty gelatin capsules :
1.Dipping
2.Spinning
3.Drying
4.Stripping
5.Trimming
6.Joining
7.Polishing
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 5
Manufacturing process of HGC
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 6
•ADVANTAGES OF HGC :-
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 7
1. Capsules are tasteless, odorless.
2. Combination of powders we can use.
3. They are attractive in appearance.
4. They can be filled quickly and conveniently.
5. They are economical.
6. They are easy to handle and carry.
7. Easy to swallow.
8. Physician can change the dose and
combination of drug according to patient
requirement.
• DISADVANTAGE OF HGC :-
1. Capsules are not suitable for liquids that dissolve
gelatin, such as aqueous or hydro alcoholic solutions.
2. The concentrated solutions which require previous
dilution are unsuitable for capsules because if
administered as such lead to irritation into stomach.
3. Not useful for efflorescent or deliquescent materials.
4. Efflorescent cause capsules to soften & Deliquescent
may dry the capsule shell to brittleness.
5. More expensive.
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 8
2. SOFT GELATIN CAPSULE :-
• Soft Gelatin capsules are one piece, hermetically
sealed, soft gelatin shells containing a liquid, a
suspension, or a semisolid.
• Soft gelatin is mainly composed of gelatin, plasticizers,
preservative, colouring and opacifying agents, flavoring
agents and sugars.
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 9
• Manufacturing process of soft gelatin
capsule :-
Methods for manufacturing of SGC :-
1. Plate – process
2. Rotary die method
3. Norton capsule machine
4. Accogel capsule machine
5. Globex method
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 10
Manufacturing process
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 11
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 12
• ADVANTAGES OF SGC :-
1. They are easy to administer.
2. Easy to manufacture.
3. Liquid can be encapsulated.
4. Small to large sizes possible.
5. Elegance
6. Portability
7. Odour & taste masking
8. Ready availability of drug hence gives fast action.
• DISADVANTAGES OF SGC :-
1. Water soluble material & are difficult to incorporate.
2. Highly moisture sensitive.
3. Efflorescent material can be incorporated , they may
cause softening.
4. Deliquescent material not used.
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 13
• APPLICATIONS OF SGC :-
1. Wate immisable, volatile & non-volatile liq. such as
vegetable & aromatic oils,aromatic & aliphatic
hydrocarbon , Chlorinated hydrocarbon, ether, ester,
alcohol.
2. Water miscible non volatile liq. Such as polyethylene
glycol, nonionic surface active agent as poly sorbate
80.
3. Water miscible & relatively non vol.Compounds
4. As a suppository dosage form.
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 14
Difference between SGC &
HGC
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 15
....Thank you....
28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 16

Weitere ähnliche Inhalte

Ă„hnlich wie Types of capsules by Sakshi Lodha

A PROJECT REPORT ON
A PROJECT REPORT ONA PROJECT REPORT ON
A PROJECT REPORT ONAnkush Biswas
 
Oral Dispersible Tablets - A Review
Oral Dispersible Tablets - A ReviewOral Dispersible Tablets - A Review
Oral Dispersible Tablets - A Reviewpharmaindexing
 
DESIGN & FORMULATION OF CAPSULES
DESIGN & FORMULATION OF CAPSULESDESIGN & FORMULATION OF CAPSULES
DESIGN & FORMULATION OF CAPSULESAnjali Teresa
 
DESIGN AND FORMULATION OF CAPSULES
DESIGN AND FORMULATION OF CAPSULESDESIGN AND FORMULATION OF CAPSULES
DESIGN AND FORMULATION OF CAPSULESAnjali Teresa
 
powder-211021064722.pptx
powder-211021064722.pptxpowder-211021064722.pptx
powder-211021064722.pptxsafa98
 
Soft and hard gelatin capsules
Soft  and hard gelatin capsules Soft  and hard gelatin capsules
Soft and hard gelatin capsules Shmmon AHMAD
 
Industrial training report 2 United institute of pharmacy
Industrial training report 2 United institute of pharmacy Industrial training report 2 United institute of pharmacy
Industrial training report 2 United institute of pharmacy moanas3
 
Role of Retail Pharmacist for Product Stability.ppt
Role of Retail Pharmacist for Product Stability.pptRole of Retail Pharmacist for Product Stability.ppt
Role of Retail Pharmacist for Product Stability.pptVishnuPatel81
 
Capsules. Their Types, manufacturing and packaging.pdf
Capsules. Their Types, manufacturing and packaging.pdfCapsules. Their Types, manufacturing and packaging.pdf
Capsules. Their Types, manufacturing and packaging.pdfShakeelIjaz3
 
A Review on Dispersible Tablets A Novel Drug Delivery System for Pedietrics a...
A Review on Dispersible Tablets A Novel Drug Delivery System for Pedietrics a...A Review on Dispersible Tablets A Novel Drug Delivery System for Pedietrics a...
A Review on Dispersible Tablets A Novel Drug Delivery System for Pedietrics a...ijtsrd
 
FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF CARVEDILOL
FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF CARVEDILOLFORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF CARVEDILOL
FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF CARVEDILOLANURAG GROUP OF INSTITUTIONS
 
Formulation Development and Evaluation of Carbamazepine Fast Dissolving Tablets
Formulation Development and Evaluation of Carbamazepine Fast Dissolving TabletsFormulation Development and Evaluation of Carbamazepine Fast Dissolving Tablets
Formulation Development and Evaluation of Carbamazepine Fast Dissolving TabletsDr. Raghavendra Kumar Gunda
 

Ă„hnlich wie Types of capsules by Sakshi Lodha (20)

Capsules
CapsulesCapsules
Capsules
 
A PROJECT REPORT ON
A PROJECT REPORT ONA PROJECT REPORT ON
A PROJECT REPORT ON
 
Oral Dispersible Tablets - A Review
Oral Dispersible Tablets - A ReviewOral Dispersible Tablets - A Review
Oral Dispersible Tablets - A Review
 
FORMULATION AND EVALUATION OF ORODISPERSIBLE TABLETS OF AMLODIPINE BESILATEIj...
FORMULATION AND EVALUATION OF ORODISPERSIBLE TABLETS OF AMLODIPINE BESILATEIj...FORMULATION AND EVALUATION OF ORODISPERSIBLE TABLETS OF AMLODIPINE BESILATEIj...
FORMULATION AND EVALUATION OF ORODISPERSIBLE TABLETS OF AMLODIPINE BESILATEIj...
 
DESIGN & FORMULATION OF CAPSULES
DESIGN & FORMULATION OF CAPSULESDESIGN & FORMULATION OF CAPSULES
DESIGN & FORMULATION OF CAPSULES
 
DESIGN AND FORMULATION OF CAPSULES
DESIGN AND FORMULATION OF CAPSULESDESIGN AND FORMULATION OF CAPSULES
DESIGN AND FORMULATION OF CAPSULES
 
Capsule
CapsuleCapsule
Capsule
 
Capsule
CapsuleCapsule
Capsule
 
powder-211021064722.pptx
powder-211021064722.pptxpowder-211021064722.pptx
powder-211021064722.pptx
 
Soft and hard gelatin capsules
Soft  and hard gelatin capsules Soft  and hard gelatin capsules
Soft and hard gelatin capsules
 
Industrial training report 2 United institute of pharmacy
Industrial training report 2 United institute of pharmacy Industrial training report 2 United institute of pharmacy
Industrial training report 2 United institute of pharmacy
 
Role of Retail Pharmacist for Product Stability.ppt
Role of Retail Pharmacist for Product Stability.pptRole of Retail Pharmacist for Product Stability.ppt
Role of Retail Pharmacist for Product Stability.ppt
 
Capsules
CapsulesCapsules
Capsules
 
Capsules. Their Types, manufacturing and packaging.pdf
Capsules. Their Types, manufacturing and packaging.pdfCapsules. Their Types, manufacturing and packaging.pdf
Capsules. Their Types, manufacturing and packaging.pdf
 
Capsule's
Capsule'sCapsule's
Capsule's
 
Capsule
CapsuleCapsule
Capsule
 
Capsules
CapsulesCapsules
Capsules
 
A Review on Dispersible Tablets A Novel Drug Delivery System for Pedietrics a...
A Review on Dispersible Tablets A Novel Drug Delivery System for Pedietrics a...A Review on Dispersible Tablets A Novel Drug Delivery System for Pedietrics a...
A Review on Dispersible Tablets A Novel Drug Delivery System for Pedietrics a...
 
FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF CARVEDILOL
FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF CARVEDILOLFORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF CARVEDILOL
FORMULATION AND EVALUATION OF MOUTH DISSOLVING TABLETS OF CARVEDILOL
 
Formulation Development and Evaluation of Carbamazepine Fast Dissolving Tablets
Formulation Development and Evaluation of Carbamazepine Fast Dissolving TabletsFormulation Development and Evaluation of Carbamazepine Fast Dissolving Tablets
Formulation Development and Evaluation of Carbamazepine Fast Dissolving Tablets
 

KĂĽrzlich hochgeladen

Student login on Anyboli platform.helpin
Student login on Anyboli platform.helpinStudent login on Anyboli platform.helpin
Student login on Anyboli platform.helpinRaunakKeshri1
 
Key note speaker Neum_Admir Softic_ENG.pdf
Key note speaker Neum_Admir Softic_ENG.pdfKey note speaker Neum_Admir Softic_ENG.pdf
Key note speaker Neum_Admir Softic_ENG.pdfAdmir Softic
 
Unit-IV- Pharma. Marketing Channels.pptx
Unit-IV- Pharma. Marketing Channels.pptxUnit-IV- Pharma. Marketing Channels.pptx
Unit-IV- Pharma. Marketing Channels.pptxVishalSingh1417
 
SOCIAL AND HISTORICAL CONTEXT - LFTVD.pptx
SOCIAL AND HISTORICAL CONTEXT - LFTVD.pptxSOCIAL AND HISTORICAL CONTEXT - LFTVD.pptx
SOCIAL AND HISTORICAL CONTEXT - LFTVD.pptxiammrhaywood
 
Grant Readiness 101 TechSoup and Remy Consulting
Grant Readiness 101 TechSoup and Remy ConsultingGrant Readiness 101 TechSoup and Remy Consulting
Grant Readiness 101 TechSoup and Remy ConsultingTechSoup
 
social pharmacy d-pharm 1st year by Pragati K. Mahajan
social pharmacy d-pharm 1st year by Pragati K. Mahajansocial pharmacy d-pharm 1st year by Pragati K. Mahajan
social pharmacy d-pharm 1st year by Pragati K. Mahajanpragatimahajan3
 
IGNOU MSCCFT and PGDCFT Exam Question Pattern: MCFT003 Counselling and Family...
IGNOU MSCCFT and PGDCFT Exam Question Pattern: MCFT003 Counselling and Family...IGNOU MSCCFT and PGDCFT Exam Question Pattern: MCFT003 Counselling and Family...
IGNOU MSCCFT and PGDCFT Exam Question Pattern: MCFT003 Counselling and Family...PsychoTech Services
 
Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...
Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...
Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...christianmathematics
 
Measures of Dispersion and Variability: Range, QD, AD and SD
Measures of Dispersion and Variability: Range, QD, AD and SDMeasures of Dispersion and Variability: Range, QD, AD and SD
Measures of Dispersion and Variability: Range, QD, AD and SDThiyagu K
 
Sanyam Choudhary Chemistry practical.pdf
Sanyam Choudhary Chemistry practical.pdfSanyam Choudhary Chemistry practical.pdf
Sanyam Choudhary Chemistry practical.pdfsanyamsingh5019
 
Sports & Fitness Value Added Course FY..
Sports & Fitness Value Added Course FY..Sports & Fitness Value Added Course FY..
Sports & Fitness Value Added Course FY..Disha Kariya
 
A Critique of the Proposed National Education Policy Reform
A Critique of the Proposed National Education Policy ReformA Critique of the Proposed National Education Policy Reform
A Critique of the Proposed National Education Policy ReformChameera Dedduwage
 
The Most Excellent Way | 1 Corinthians 13
The Most Excellent Way | 1 Corinthians 13The Most Excellent Way | 1 Corinthians 13
The Most Excellent Way | 1 Corinthians 13Steve Thomason
 
Interactive Powerpoint_How to Master effective communication
Interactive Powerpoint_How to Master effective communicationInteractive Powerpoint_How to Master effective communication
Interactive Powerpoint_How to Master effective communicationnomboosow
 
fourth grading exam for kindergarten in writing
fourth grading exam for kindergarten in writingfourth grading exam for kindergarten in writing
fourth grading exam for kindergarten in writingTeacherCyreneCayanan
 
microwave assisted reaction. General introduction
microwave assisted reaction. General introductionmicrowave assisted reaction. General introduction
microwave assisted reaction. General introductionMaksud Ahmed
 
Nutritional Needs Presentation - HLTH 104
Nutritional Needs Presentation - HLTH 104Nutritional Needs Presentation - HLTH 104
Nutritional Needs Presentation - HLTH 104misteraugie
 
Russian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in Delhi
Russian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in DelhiRussian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in Delhi
Russian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in Delhikauryashika82
 
The basics of sentences session 2pptx copy.pptx
The basics of sentences session 2pptx copy.pptxThe basics of sentences session 2pptx copy.pptx
The basics of sentences session 2pptx copy.pptxheathfieldcps1
 
Web & Social Media Analytics Previous Year Question Paper.pdf
Web & Social Media Analytics Previous Year Question Paper.pdfWeb & Social Media Analytics Previous Year Question Paper.pdf
Web & Social Media Analytics Previous Year Question Paper.pdfJayanti Pande
 

KĂĽrzlich hochgeladen (20)

Student login on Anyboli platform.helpin
Student login on Anyboli platform.helpinStudent login on Anyboli platform.helpin
Student login on Anyboli platform.helpin
 
Key note speaker Neum_Admir Softic_ENG.pdf
Key note speaker Neum_Admir Softic_ENG.pdfKey note speaker Neum_Admir Softic_ENG.pdf
Key note speaker Neum_Admir Softic_ENG.pdf
 
Unit-IV- Pharma. Marketing Channels.pptx
Unit-IV- Pharma. Marketing Channels.pptxUnit-IV- Pharma. Marketing Channels.pptx
Unit-IV- Pharma. Marketing Channels.pptx
 
SOCIAL AND HISTORICAL CONTEXT - LFTVD.pptx
SOCIAL AND HISTORICAL CONTEXT - LFTVD.pptxSOCIAL AND HISTORICAL CONTEXT - LFTVD.pptx
SOCIAL AND HISTORICAL CONTEXT - LFTVD.pptx
 
Grant Readiness 101 TechSoup and Remy Consulting
Grant Readiness 101 TechSoup and Remy ConsultingGrant Readiness 101 TechSoup and Remy Consulting
Grant Readiness 101 TechSoup and Remy Consulting
 
social pharmacy d-pharm 1st year by Pragati K. Mahajan
social pharmacy d-pharm 1st year by Pragati K. Mahajansocial pharmacy d-pharm 1st year by Pragati K. Mahajan
social pharmacy d-pharm 1st year by Pragati K. Mahajan
 
IGNOU MSCCFT and PGDCFT Exam Question Pattern: MCFT003 Counselling and Family...
IGNOU MSCCFT and PGDCFT Exam Question Pattern: MCFT003 Counselling and Family...IGNOU MSCCFT and PGDCFT Exam Question Pattern: MCFT003 Counselling and Family...
IGNOU MSCCFT and PGDCFT Exam Question Pattern: MCFT003 Counselling and Family...
 
Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...
Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...
Explore beautiful and ugly buildings. Mathematics helps us create beautiful d...
 
Measures of Dispersion and Variability: Range, QD, AD and SD
Measures of Dispersion and Variability: Range, QD, AD and SDMeasures of Dispersion and Variability: Range, QD, AD and SD
Measures of Dispersion and Variability: Range, QD, AD and SD
 
Sanyam Choudhary Chemistry practical.pdf
Sanyam Choudhary Chemistry practical.pdfSanyam Choudhary Chemistry practical.pdf
Sanyam Choudhary Chemistry practical.pdf
 
Sports & Fitness Value Added Course FY..
Sports & Fitness Value Added Course FY..Sports & Fitness Value Added Course FY..
Sports & Fitness Value Added Course FY..
 
A Critique of the Proposed National Education Policy Reform
A Critique of the Proposed National Education Policy ReformA Critique of the Proposed National Education Policy Reform
A Critique of the Proposed National Education Policy Reform
 
The Most Excellent Way | 1 Corinthians 13
The Most Excellent Way | 1 Corinthians 13The Most Excellent Way | 1 Corinthians 13
The Most Excellent Way | 1 Corinthians 13
 
Interactive Powerpoint_How to Master effective communication
Interactive Powerpoint_How to Master effective communicationInteractive Powerpoint_How to Master effective communication
Interactive Powerpoint_How to Master effective communication
 
fourth grading exam for kindergarten in writing
fourth grading exam for kindergarten in writingfourth grading exam for kindergarten in writing
fourth grading exam for kindergarten in writing
 
microwave assisted reaction. General introduction
microwave assisted reaction. General introductionmicrowave assisted reaction. General introduction
microwave assisted reaction. General introduction
 
Nutritional Needs Presentation - HLTH 104
Nutritional Needs Presentation - HLTH 104Nutritional Needs Presentation - HLTH 104
Nutritional Needs Presentation - HLTH 104
 
Russian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in Delhi
Russian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in DelhiRussian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in Delhi
Russian Escort Service in Delhi 11k Hotel Foreigner Russian Call Girls in Delhi
 
The basics of sentences session 2pptx copy.pptx
The basics of sentences session 2pptx copy.pptxThe basics of sentences session 2pptx copy.pptx
The basics of sentences session 2pptx copy.pptx
 
Web & Social Media Analytics Previous Year Question Paper.pdf
Web & Social Media Analytics Previous Year Question Paper.pdfWeb & Social Media Analytics Previous Year Question Paper.pdf
Web & Social Media Analytics Previous Year Question Paper.pdf
 

Types of capsules by Sakshi Lodha

  • 1. Presented By : Lodha Sakshi Mahendra Roll no : 31 Class : T.Y B.Pharmacy Assig. Topic : Types of capsules Guided by : Mrs. N.S.Baste Mam SNJB’S SSDJ COLLEGE OF PHARMACY , CHANDWAD. 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 1
  • 2. TYPES OF CAPSULE :- 1. Hard Gelatin Capsule 2. Soft Gelatin Capsule 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) CAPSULESđź’Š Hard capsules Soft Capsules
  • 3. 1. HARD GELATIN CAPSULES :- • The hard gelatin capsule consists of two pieces in the form of cylinders closed at one end. • The shorter piece is called the cap. This cap fits over the open end of longer piece called body. • Hard gelatin capsules are also known as dry-filled capsules or two piece capsules. • This capsules are used in extemporaneous compounding of Rx. 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 3
  • 4. • This capsules are made up of gelatin , sugar and water. • HGC are tasteless. • Colour with various FD & C and D & C dyes. • They made opaque by addition of Titanium Dioxide. 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 4
  • 5. •Manufacturing of Hard gelatin capsules :- Steps involved in making empty gelatin capsules : 1.Dipping 2.Spinning 3.Drying 4.Stripping 5.Trimming 6.Joining 7.Polishing 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 5
  • 6. Manufacturing process of HGC 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 6
  • 7. •ADVANTAGES OF HGC :- 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 7 1. Capsules are tasteless, odorless. 2. Combination of powders we can use. 3. They are attractive in appearance. 4. They can be filled quickly and conveniently. 5. They are economical. 6. They are easy to handle and carry. 7. Easy to swallow. 8. Physician can change the dose and combination of drug according to patient requirement.
  • 8. • DISADVANTAGE OF HGC :- 1. Capsules are not suitable for liquids that dissolve gelatin, such as aqueous or hydro alcoholic solutions. 2. The concentrated solutions which require previous dilution are unsuitable for capsules because if administered as such lead to irritation into stomach. 3. Not useful for efflorescent or deliquescent materials. 4. Efflorescent cause capsules to soften & Deliquescent may dry the capsule shell to brittleness. 5. More expensive. 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 8
  • 9. 2. SOFT GELATIN CAPSULE :- • Soft Gelatin capsules are one piece, hermetically sealed, soft gelatin shells containing a liquid, a suspension, or a semisolid. • Soft gelatin is mainly composed of gelatin, plasticizers, preservative, colouring and opacifying agents, flavoring agents and sugars. 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 9
  • 10. • Manufacturing process of soft gelatin capsule :- Methods for manufacturing of SGC :- 1. Plate – process 2. Rotary die method 3. Norton capsule machine 4. Accogel capsule machine 5. Globex method 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 10
  • 11. Manufacturing process 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 11
  • 12. 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 12 • ADVANTAGES OF SGC :- 1. They are easy to administer. 2. Easy to manufacture. 3. Liquid can be encapsulated. 4. Small to large sizes possible. 5. Elegance 6. Portability 7. Odour & taste masking 8. Ready availability of drug hence gives fast action.
  • 13. • DISADVANTAGES OF SGC :- 1. Water soluble material & are difficult to incorporate. 2. Highly moisture sensitive. 3. Efflorescent material can be incorporated , they may cause softening. 4. Deliquescent material not used. 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 13
  • 14. • APPLICATIONS OF SGC :- 1. Wate immisable, volatile & non-volatile liq. such as vegetable & aromatic oils,aromatic & aliphatic hydrocarbon , Chlorinated hydrocarbon, ether, ester, alcohol. 2. Water miscible non volatile liq. Such as polyethylene glycol, nonionic surface active agent as poly sorbate 80. 3. Water miscible & relatively non vol.Compounds 4. As a suppository dosage form. 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 14
  • 15. Difference between SGC & HGC 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 15
  • 16. ....Thank you.... 28 March 2023 SNJB's SSDJ College of Pharmacy, Chandwad (Nasik) 16