Sepsis

1. SEPSIS
Reporter:XXX

2. The term sepsis has been used for a clinical situation in
which there is evidence of
infection plus a systemic response as manifested by an
elevated temperature,
tachycardia,increased respiration, leukocytosis or an
impaired peripheral leukocyte response,
and/or the presence of immature band forms of
peripheral circulation.

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4. CLASSIFICATION
According to spreading of the
disease:
1. Purulent – resorptive fever is characterized by
presence of purulent foci, wave-like course,
general intoxication.
2. Septicemia is characterized by severe general
state, hectic temperature, severe disorders of
central nervous system and cardiovascular
system.

5. 3. Septicopyemia. This is combination of
septicemia and presence of secondary
purulent foci in different organs.
4. Chronic sepsis. There is purulent foci in
anamnesis during this form. The diseases is
accompanied by prolonged wave-like fever,
presence of period of remission and
relapses,
periodical formation of purulent foci.

7. CLASSIFICATION
According to prolongation of course the next form of the
diseases are differed::
1.Fulminant sepsis (24-48 hours)
2.Acute sepsis (from 5-7 days till some
weeks)
3.Subacute sepsis (3-4 months)
4.Chronic sepsis (from some month till one
year and more)

8. CLASSIFICATION
According to date appearance of process the next variants
are differed:
1.Early sepsis (till 3 months from
appearance of the primary focus)
2.Late sepsis ( later than 3 months)

9. CLASSIFICATION
According to character of microorganism sepsis is differed
on:
Sepsis, caused by gram-positive flora. It
leads, inrarely, to development of
septicopyemia.
Sepsis, caused by gram-negative flora.
Infectious-toxic shock may be in such cases.

12. CLINICAL MANIFESTATION
Complains of these patients are different as a clinical manifestations –
weakness,
headache, pain in joints, chill with following sweats or chilling, dry
mucous membrane of the
mouth, poor appetite, sometimes – diarrhea.
Fever is frequently of hectic character in patients with sepsis. Different
variants of the
temperature may be – remittent and intermittent types, sometimes, –
the temperature is more
high in the morning (the reversal type). The temperature may be not
high in weak, cachestic
patients and elders, but it doesn’t report about light course of sepsis.

13. skin is pale, moist, even icteric in severe cases. Different rashes
are observed.
Rash of hemorrhagic type is marked more frequently, sometimes
– pustules, ulcers, erythema.
Eruption may be on skin of trunk, limbs and face.

14. Mucous membranes of lips, oral cavity are dry and may have
erosions, ulcers, fissures,
bleeding sickness. Often, there are hemorrhages of
conjunctiva.
Pulse is frequent. Arterial
pressure decreases. Heart
is enlarged. There are a
systolic
murmur above cardiac
apex, tachycardia and
“pendulous” rhythm during
auscultation the
alterations of myocardium
are revealed during
cardiogram.
alterations of respiratory
tract are revealed
frequently in the patients
with sepsis:
dyspnoe, bronchitis and
pneumonia.
Osseous-muscular system is
involved to pathologic process, too.
There are reports
about the serous and purulent
mono- and polyarthritis,

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