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 Tb of the spine or Pott’s disease is a
presentation of extrapulmonary
tuberculosis that affects the spine,
 a kind of tuberculous arthritis of the
intervertebral joints.
 The lower thoracic and upper lumbar
vertebrae are the areas of the spine most
often affected.
 Scientifically, it is called tuberculous
spondylitis
 Pott’s disease results from haematogenous
spread of tuberculosis from other sites, often
pulmonary.
 The infection then spreads from two adjacent
vertebrae into the adjoining intervetebral disc
space.
 If only one vertebra is affected, the disc is
normal, but if two are involved, the disc, which
is avascular, cannot receive nutrients and
collapses.
 The disc tissue dies leading to intervertebral
space narrowing and eventually to vertebral
collapse and spinal damage.
 Incidence
 In the United States, bone and soft
tissue tuberculosis accounts for
approximately 10% of extrapulmonary
TB cases and between 1% and 2% of
total cases.
 Of these cases, Pott’s disease is the
most common manifestation of
musculoskeletal TB, accounting for
approximately 40-50%.
 Ethnicity
Data from the United States show that
musculoskeletal tuberculosis primarily
affects African Americans, Hispanic
Americans, Asian Americans, and
foreign-born individuals.
 Gender
Although some studies have found that
Pott’s disease does not have sexual
predilection, the disease is more
common in males.
 The male to female ratio is reportedly
1.5-2:1.
 Age
In the United States and other
developed countries, Pott’s disease
occurs primarily in adults.
 In underdeveloped countries which have
higher rates of Pott’s disease,
involvement in young adults and older
children predominates.
 back pain
 Fever
 Tenderness on furrow of the back
 night sweating
 anorexia
 Spinal mass, sometimes associated with
numbness, paraesthesia, or muscle
weakness of the legs
 Restriction of spinal movements
 blood tests
 elevated erythrocyte sedimentation rate
>100 mm/h
 Mantoux test results are positive in 84-
95% of patients with Pott disease who
are not infected with HIV.
 radiographs of the spine:
 Radiographic changes associated with
Pott’s disease present relatively late.
 Lytic destruction of anterior portion of
vertebral body
 Increased anterior wedging
 Collapse of vertebral body
 Reactive sclerosis on a progressive lytic
process
 Enlarged psoas shadow with or without
calcification
 bone scan
 CT of the spine
 bone biopsy
 MRI
 Vertebral collapse resulting in kyphosis
 Spinal cord compression
 Nerve root compression
 sinus formation
 paraplegia (so called Pott's paraplegia)
 Disc herniation
 Psoas abscess
 Cauda equina syndrome
 The medical management is mainly
focused to eliminate the infection and
pain suppression
 antituberculous drugs(rifampicin,
isoniazid,pyrazinamide,ethambutol and
streptomycin
 Analgesics(pethidine,diclofenac)
 Surgery may be necessary, especially to
drain spinal abscesses or to stabilize the
spine
 Thoracic spinal fusion is done as a last
resort
 Muscle strength mx:
 Walking Program
 Aerobic Exercise
 Trunk Strengthening
 Spinal stabilization excersizes
 Pain mx:
 Hydrotherapy Therapy
 TENS
 Interferential therapy
 Excersizes focusing on muscles of the
back can strenghthen them preventing
further kyphosis
 Electrotherapy modalities are usefull in
alleviating pain
 Since physio mx is mainly focused on
pain and muscle strength it can’t :
 Reverse the bone destruction that takes
place
 The necrosis that would have occurred
to ivds
 stop the progression of the diseases
 Modalities like ift can’t be used directly
on the vertebral column hence its effects
are not maxmal
 Continued exercesizes might give a
muslce cast in the deformed position
 Prognosis is variable, some individuals will
recover completely,particularly if the
infection has been cured.
 Those requiring longterm suppressive
therapy may develop recurrences if drug
therapy is not maintained
 Although spinal fusion maybe effective in
relieving pain discomfort depending on the
severity of the symptoms, surgery will not
however treat the underlying disease
 In the past prior to discovery of drugs for
Tb, 20% of patients died and 30% had
recurrence of their symptoms.
 Apley’s orthopaedic textbook, Cleveland
clinic journal of
medicine,www.physiopedia.com,
www.pubmed.com.

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Tuberculosis of the spine

  • 1.
  • 2.  Tb of the spine or Pott’s disease is a presentation of extrapulmonary tuberculosis that affects the spine,  a kind of tuberculous arthritis of the intervertebral joints.  The lower thoracic and upper lumbar vertebrae are the areas of the spine most often affected.  Scientifically, it is called tuberculous spondylitis
  • 3.
  • 4.
  • 5.  Pott’s disease results from haematogenous spread of tuberculosis from other sites, often pulmonary.  The infection then spreads from two adjacent vertebrae into the adjoining intervetebral disc space.  If only one vertebra is affected, the disc is normal, but if two are involved, the disc, which is avascular, cannot receive nutrients and collapses.  The disc tissue dies leading to intervertebral space narrowing and eventually to vertebral collapse and spinal damage.
  • 6.  Incidence  In the United States, bone and soft tissue tuberculosis accounts for approximately 10% of extrapulmonary TB cases and between 1% and 2% of total cases.  Of these cases, Pott’s disease is the most common manifestation of musculoskeletal TB, accounting for approximately 40-50%.
  • 7.  Ethnicity Data from the United States show that musculoskeletal tuberculosis primarily affects African Americans, Hispanic Americans, Asian Americans, and foreign-born individuals.
  • 8.  Gender Although some studies have found that Pott’s disease does not have sexual predilection, the disease is more common in males.  The male to female ratio is reportedly 1.5-2:1.
  • 9.  Age In the United States and other developed countries, Pott’s disease occurs primarily in adults.  In underdeveloped countries which have higher rates of Pott’s disease, involvement in young adults and older children predominates.
  • 10.  back pain  Fever  Tenderness on furrow of the back  night sweating  anorexia  Spinal mass, sometimes associated with numbness, paraesthesia, or muscle weakness of the legs  Restriction of spinal movements
  • 11.
  • 12.  blood tests  elevated erythrocyte sedimentation rate >100 mm/h  Mantoux test results are positive in 84- 95% of patients with Pott disease who are not infected with HIV.
  • 13.  radiographs of the spine:  Radiographic changes associated with Pott’s disease present relatively late.  Lytic destruction of anterior portion of vertebral body  Increased anterior wedging  Collapse of vertebral body  Reactive sclerosis on a progressive lytic process  Enlarged psoas shadow with or without calcification
  • 14.
  • 15.
  • 16.
  • 17.  bone scan  CT of the spine  bone biopsy  MRI
  • 18.
  • 19.  Vertebral collapse resulting in kyphosis  Spinal cord compression  Nerve root compression  sinus formation  paraplegia (so called Pott's paraplegia)  Disc herniation  Psoas abscess  Cauda equina syndrome
  • 20.  The medical management is mainly focused to eliminate the infection and pain suppression  antituberculous drugs(rifampicin, isoniazid,pyrazinamide,ethambutol and streptomycin  Analgesics(pethidine,diclofenac)
  • 21.  Surgery may be necessary, especially to drain spinal abscesses or to stabilize the spine  Thoracic spinal fusion is done as a last resort
  • 22.  Muscle strength mx:  Walking Program  Aerobic Exercise  Trunk Strengthening  Spinal stabilization excersizes
  • 23.  Pain mx:  Hydrotherapy Therapy  TENS  Interferential therapy
  • 24.  Excersizes focusing on muscles of the back can strenghthen them preventing further kyphosis  Electrotherapy modalities are usefull in alleviating pain
  • 25.  Since physio mx is mainly focused on pain and muscle strength it can’t :  Reverse the bone destruction that takes place  The necrosis that would have occurred to ivds  stop the progression of the diseases
  • 26.  Modalities like ift can’t be used directly on the vertebral column hence its effects are not maxmal  Continued exercesizes might give a muslce cast in the deformed position
  • 27.  Prognosis is variable, some individuals will recover completely,particularly if the infection has been cured.  Those requiring longterm suppressive therapy may develop recurrences if drug therapy is not maintained  Although spinal fusion maybe effective in relieving pain discomfort depending on the severity of the symptoms, surgery will not however treat the underlying disease
  • 28.  In the past prior to discovery of drugs for Tb, 20% of patients died and 30% had recurrence of their symptoms.
  • 29.  Apley’s orthopaedic textbook, Cleveland clinic journal of medicine,www.physiopedia.com, www.pubmed.com.