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Tuberculosis of the spine
1.
2. Tb of the spine or Pott’s disease is a
presentation of extrapulmonary
tuberculosis that affects the spine,
a kind of tuberculous arthritis of the
intervertebral joints.
The lower thoracic and upper lumbar
vertebrae are the areas of the spine most
often affected.
Scientifically, it is called tuberculous
spondylitis
3.
4.
5. Pott’s disease results from haematogenous
spread of tuberculosis from other sites, often
pulmonary.
The infection then spreads from two adjacent
vertebrae into the adjoining intervetebral disc
space.
If only one vertebra is affected, the disc is
normal, but if two are involved, the disc, which
is avascular, cannot receive nutrients and
collapses.
The disc tissue dies leading to intervertebral
space narrowing and eventually to vertebral
collapse and spinal damage.
6. Incidence
In the United States, bone and soft
tissue tuberculosis accounts for
approximately 10% of extrapulmonary
TB cases and between 1% and 2% of
total cases.
Of these cases, Pott’s disease is the
most common manifestation of
musculoskeletal TB, accounting for
approximately 40-50%.
7. Ethnicity
Data from the United States show that
musculoskeletal tuberculosis primarily
affects African Americans, Hispanic
Americans, Asian Americans, and
foreign-born individuals.
8. Gender
Although some studies have found that
Pott’s disease does not have sexual
predilection, the disease is more
common in males.
The male to female ratio is reportedly
1.5-2:1.
9. Age
In the United States and other
developed countries, Pott’s disease
occurs primarily in adults.
In underdeveloped countries which have
higher rates of Pott’s disease,
involvement in young adults and older
children predominates.
10. back pain
Fever
Tenderness on furrow of the back
night sweating
anorexia
Spinal mass, sometimes associated with
numbness, paraesthesia, or muscle
weakness of the legs
Restriction of spinal movements
11.
12. blood tests
elevated erythrocyte sedimentation rate
>100 mm/h
Mantoux test results are positive in 84-
95% of patients with Pott disease who
are not infected with HIV.
13. radiographs of the spine:
Radiographic changes associated with
Pott’s disease present relatively late.
Lytic destruction of anterior portion of
vertebral body
Increased anterior wedging
Collapse of vertebral body
Reactive sclerosis on a progressive lytic
process
Enlarged psoas shadow with or without
calcification
20. The medical management is mainly
focused to eliminate the infection and
pain suppression
antituberculous drugs(rifampicin,
isoniazid,pyrazinamide,ethambutol and
streptomycin
Analgesics(pethidine,diclofenac)
21. Surgery may be necessary, especially to
drain spinal abscesses or to stabilize the
spine
Thoracic spinal fusion is done as a last
resort
24. Excersizes focusing on muscles of the
back can strenghthen them preventing
further kyphosis
Electrotherapy modalities are usefull in
alleviating pain
25. Since physio mx is mainly focused on
pain and muscle strength it can’t :
Reverse the bone destruction that takes
place
The necrosis that would have occurred
to ivds
stop the progression of the diseases
26. Modalities like ift can’t be used directly
on the vertebral column hence its effects
are not maxmal
Continued exercesizes might give a
muslce cast in the deformed position
27. Prognosis is variable, some individuals will
recover completely,particularly if the
infection has been cured.
Those requiring longterm suppressive
therapy may develop recurrences if drug
therapy is not maintained
Although spinal fusion maybe effective in
relieving pain discomfort depending on the
severity of the symptoms, surgery will not
however treat the underlying disease
28. In the past prior to discovery of drugs for
Tb, 20% of patients died and 30% had
recurrence of their symptoms.