8. Wholebrainmetabolismwhen the cognitive taskwasgivenwith: Placebo increased 21% Methylphenidateincreased 11% (50% less) FromVolkow N.D. et al, PLoS ONE 2008
9. Methylphenidatereducesenergyintake and dietary fat intakeduring a buffet-style meal in adults Variable Mean change (%) Energyintake -11* Fat intake -17* Values are means * Significantdifference versus a placebo condition: p < 0.05 Adaptedfrom Goldfield GS. AJCN 86: 308-315, 2007
10. Treatment: Medications used include mixed salts amphetamine (Adderall XR), mythylphenidate sustained-release capsule (Concerta), and sustained release destroamphetamine sulfate (Dexedrine Spansules). All participants, including control subjects, were offered individual assessment and diet instruction by the clinicâs registered dietitian. All participants were counselled regarding the need to be physically more activie. Duration of ADHD management: 466 days
11. Body weight changes with ADHD management ADHD-treated subjects Untreated controls (n = 65) (n = 13) body weight (kg) -15.05 +3.26* (%) -12.36 +2.78* *Significant difference between groups, p < 0.001 Adapted from Levy LD et al, Int J Obes 33: 326-334, 2009