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PowerPoint® Lecture Slides prepared by Vince Austin, University of Kentucky 
The Cardiovascular System: Blood Vessels 
19 
Human Anatomy & Physiology, Sixth Edition 
Elaine N. Marieb 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Blood Vessels 
 Blood is carried in a closed system of vessels that begins and 
ends at the heart 
 The three major types of vessels are arteries, capillaries, 
and veins 
 Arteries carry blood away from the heart 
 Veins carry blood toward the heart 
 Capillaries contact tissue cells and directly serve cellular 
needs 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Generalized Structure of Blood Vessels 
 Arteries and veins are composed of three tunics – tunica 
interna, tunica media, and tunica externa 
 Lumen – central blood-containing space surrounded by 
tunics 
 Capillaries are composed of endothelium with sparse basal 
lamina 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Generalized Structure of Blood Vessels 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 19.1b
Tunics 
Tunica interna (tunica intima) 
 Endothelial layer that lines the lumen of all vessels 
 In vessels larger than 1 mm, a subendothelial connective 
tissue basement membrane is present 
Tunica media 
 Smooth muscle and elastic fiber layer, regulated by 
sympathetic nervous system 
 Controls vasoconstriction/vasodilation of vessels 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Tunics 
Tunica externa (tunica adventitia) 
 Collagen fibers that protect and reinforce vessels 
 Larger vessels contain vasa vasorum 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Elastic (Conducting) Arteries 
Thick-walled arteries - near the heart; the aorta and its major 
branches 
 Large lumen allow low-resistance conduction of blood 
 Contain elastin in all three tunics 
 Withstand and smooth out large blood pressure 
fluctuations 
 Allow blood to flow fairly continuously through the body 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Muscular (Distributing) Arteries and Arterioles 
Muscular arteries – distal to elastic arteries; deliver blood to 
body organs 
 Have thick tunica media with more smooth muscle and 
less elastic tissue 
 Active in vasoconstriction 
Arterioles – smallest arteries; lead to capillary beds 
 Control flow into capillary beds via vasodilation and 
constriction 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Capillaries 
Capillaries - the smallest blood vessels 
 Walls consisting of a thin tunica interna, one cell thick 
 Allow only a single RBC to pass at a time 
There are three structural types of capillaries: continuous, 
fenestrated, and sinusoids 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Capillary Beds 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 19.4a
Capillary Beds 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 19.4b
Blood Flow Through Capillary Beds 
Precapillary sphincter 
 Cuff of smooth muscle that surrounds each true capillary 
 Regulates blood flow into the capillary 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Venous System: Venules 
Venules 
 Are formed when capillary beds unite 
 Allow fluids and WBCs to pass from the bloodstream to 
tissues 
 Large venules have one or two layers of smooth muscle 
(tunica media) 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Venous System: Veins 
Veins 
 Formed when venules converge 
 Composed of three tunics, with a thin tunica media and a 
thick tunica externa consisting of collagen fibers and 
elastic networks 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Venous System: Veins 
 Veins have much lower blood pressure and thinner walls 
than arteries 
 To return blood to the heart, veins have special adaptations 
 Large-diameter lumens, which offer little resistance to 
flow 
 Valves (resembling semilunar heart valves), which 
prevent backflow of blood 
 Venous sinuses – specialized, flattened veins with 
extremely thin walls (e.g., coronary sinus of the heart and 
dural sinuses of the brain) 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Systemic Blood Pressure 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 19.5
Factors Aiding Venous Return 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 19.6
Circulatory Pathways 
The vascular system has two distinct circulations: 
 Pulmonary circulation – short loop that runs from the 
heart to the lungs and back to the heart 
 Systemic circulation – routes blood through a long loop 
to all parts of the body and returns to the heart 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Differences Between Arteries and Veins 
Arteries Veins 
Delivery Blood pumped into single 
systemic artery – the aorta 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Blood returns via superior and 
interior venae cavae and the 
coronary sinus 
Location Deep, and protected by 
tissue Both deep and superficial 
Pathways Fair, clear, and defined Convergent interconnections 
Supply/drainage Predictable supply Dural sinuses and hepatic portal 
circulation
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 19.17a 
Pulmonary Circulation
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 19.18 
Systemic Circulation
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Know these arteries!
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Arteries of the Head and Neck 
 
 
 
 
 
  
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.20b
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Arteries of the Upper Limbs and Thorax 
 
 
 
 
 
 
 
 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
 
 

1 
2 
3 
4 
5 
6 
7 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 19.22c 
Arteries of the Abdomen 
1 
2 
3 
5 
4 
6 
7
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 19.22d 
Arteries of the Abdomen 
 
 
 
 

Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Arteries of the Lower Limbs 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 19.23b, c 
 
 
 
 
 
 
 

Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Know these veins! 
Figure 19.24b
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 19.25b 
Veins of the Head and Neck 
 
 
 
 
 
 
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 19.26b 
Veins of the Upper Limbs and Thorax 
 
 
 
 
 
 
 
 
 
 
 
 
 

Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 19.27b 
Veins of the Abdomen
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 19.27c 
Veins of the Abdomen 
 

Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings 
Figure 19.28b, c 
Veins of the Pelvis and Lower Limbs

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Chapter 19 blood vessels

  • 1. PowerPoint® Lecture Slides prepared by Vince Austin, University of Kentucky The Cardiovascular System: Blood Vessels 19 Human Anatomy & Physiology, Sixth Edition Elaine N. Marieb Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 2. Blood Vessels  Blood is carried in a closed system of vessels that begins and ends at the heart  The three major types of vessels are arteries, capillaries, and veins  Arteries carry blood away from the heart  Veins carry blood toward the heart  Capillaries contact tissue cells and directly serve cellular needs Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 3. Generalized Structure of Blood Vessels  Arteries and veins are composed of three tunics – tunica interna, tunica media, and tunica externa  Lumen – central blood-containing space surrounded by tunics  Capillaries are composed of endothelium with sparse basal lamina Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 4. Generalized Structure of Blood Vessels Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.1b
  • 5. Tunics Tunica interna (tunica intima)  Endothelial layer that lines the lumen of all vessels  In vessels larger than 1 mm, a subendothelial connective tissue basement membrane is present Tunica media  Smooth muscle and elastic fiber layer, regulated by sympathetic nervous system  Controls vasoconstriction/vasodilation of vessels Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 6. Tunics Tunica externa (tunica adventitia)  Collagen fibers that protect and reinforce vessels  Larger vessels contain vasa vasorum Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 7. Elastic (Conducting) Arteries Thick-walled arteries - near the heart; the aorta and its major branches  Large lumen allow low-resistance conduction of blood  Contain elastin in all three tunics  Withstand and smooth out large blood pressure fluctuations  Allow blood to flow fairly continuously through the body Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 8. Muscular (Distributing) Arteries and Arterioles Muscular arteries – distal to elastic arteries; deliver blood to body organs  Have thick tunica media with more smooth muscle and less elastic tissue  Active in vasoconstriction Arterioles – smallest arteries; lead to capillary beds  Control flow into capillary beds via vasodilation and constriction Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 9. Capillaries Capillaries - the smallest blood vessels  Walls consisting of a thin tunica interna, one cell thick  Allow only a single RBC to pass at a time There are three structural types of capillaries: continuous, fenestrated, and sinusoids Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 10. Capillary Beds Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.4a
  • 11. Capillary Beds Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.4b
  • 12. Blood Flow Through Capillary Beds Precapillary sphincter  Cuff of smooth muscle that surrounds each true capillary  Regulates blood flow into the capillary Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 13. Venous System: Venules Venules  Are formed when capillary beds unite  Allow fluids and WBCs to pass from the bloodstream to tissues  Large venules have one or two layers of smooth muscle (tunica media) Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 14. Venous System: Veins Veins  Formed when venules converge  Composed of three tunics, with a thin tunica media and a thick tunica externa consisting of collagen fibers and elastic networks Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 15. Venous System: Veins  Veins have much lower blood pressure and thinner walls than arteries  To return blood to the heart, veins have special adaptations  Large-diameter lumens, which offer little resistance to flow  Valves (resembling semilunar heart valves), which prevent backflow of blood  Venous sinuses – specialized, flattened veins with extremely thin walls (e.g., coronary sinus of the heart and dural sinuses of the brain) Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 16. Systemic Blood Pressure Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.5
  • 17. Factors Aiding Venous Return Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.6
  • 18. Circulatory Pathways The vascular system has two distinct circulations:  Pulmonary circulation – short loop that runs from the heart to the lungs and back to the heart  Systemic circulation – routes blood through a long loop to all parts of the body and returns to the heart Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 19. Differences Between Arteries and Veins Arteries Veins Delivery Blood pumped into single systemic artery – the aorta Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Blood returns via superior and interior venae cavae and the coronary sinus Location Deep, and protected by tissue Both deep and superficial Pathways Fair, clear, and defined Convergent interconnections Supply/drainage Predictable supply Dural sinuses and hepatic portal circulation
  • 20. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.17a Pulmonary Circulation
  • 21. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.18 Systemic Circulation
  • 22. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Know these arteries!
  • 23. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 24. Arteries of the Head and Neck        Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.20b
  • 25. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 26. Arteries of the Upper Limbs and Thorax         Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings   
  • 27. 1 2 3 4 5 6 7 Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 28. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.22c Arteries of the Abdomen 1 2 3 5 4 6 7
  • 29. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.22d Arteries of the Abdomen     
  • 30. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
  • 31. Arteries of the Lower Limbs Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.23b, c        
  • 32. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Know these veins! Figure 19.24b
  • 33. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.25b Veins of the Head and Neck       
  • 34. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.26b Veins of the Upper Limbs and Thorax              
  • 35. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.27b Veins of the Abdomen
  • 36. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.27c Veins of the Abdomen  
  • 37. Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings Figure 19.28b, c Veins of the Pelvis and Lower Limbs