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GUIDED BY
DR. VAIDEHI RAOLE
HOD
DEPARTMENT OF KRIYA
SHARIR
PRESENTED BY
DR. SUJIT KUMAR
MD 1ST YEAR
PARUL INSTITUTE OF AYURVED
CONTENTS
1. NAAM AND NIRUKTI
2. PARYAYA
3. STHANA
4. COMPOSITION OF OJAS
5. TYPES OF OJAS
6. PARINAMAN OF OJAS
7. QUALITY OF OJAS
8. PRAMAN OF OJAS
9. OJAKSHAYA KARANA
10. OJAKSHAYA LAKSHANA
11. OJAVRIDDHI LAKSHANA
12. VYADHIKSHAMATVA
13. RASAYANA
NAAM AND NIRUKTI
AÉåeÉxiÉÑiÉåeÉÉåkÉÉiÉÑlÉÉÇzÉÑ¢üÉliÉÉlÉÉÇmÉUÇ
xqÉ×iÉqÉç|A.WØû.xÉÔ.11.37
zÉÑ¢üxrÉxÉÉUqÉçAÉåeÉÈ|A.xÉ.zÉÉ.7/6
1. Ojas is the essence part of all the
dhatu and is also mentioned as Bala.
2. Considered as updhatu & shleshmika
dravya .
3. It is predominant of JALA and
PRITHIVI Mahabhuta.
PARYAYA
1. Sarva dhatu sara (Essence of all dhatu )
2. Sthirata ( Stability )
3. Sara (Essence )
4. Prasad ( Qualitative substance )
5. Jivashonitum ( Essence of life )
6. Sleshma (Covering)
7. Deepti (Hunger )
8. Kanti (Lusterness)
CHARAK
SUTRASTHAN
MAHAT , DHARI, SARVA DHATU
SNEHA
CHARAK
SUTRASTHAN
UTAKRASHAT SARA,
GHRITAVAN STHIRDHATU,
BALA
CHARAK RASA, PRAKRUTA SLESHMA
SUSHRUTA PARAM TEJA
ASHTANGA
SANGRAHA
SHUKRA SARA
DALHANA BHARADI HARANA SHAKTI,
JIVASHODITAM
STHANA
mÉëÉhÉÉ´ÉrÉxrÉ AÉåeÉxÉÉåŹÉæ ÌoÉlSuÉÉå WØûSrÉÉÍ´ÉiÉÉÈ CÌiÉ |
AkÉÉïgeÉÍsÉ mÉËUÍqÉiÉxrÉ AÉåeÉxÉÉå kÉqÉlrÉ LuÉ WØûSrÉÉÍ´ÉiÉÉÈ
xjÉÉlÉqÉç. (cÉ.xÉÔ.30:11)
1. Ojas is finest product of all the seven
dhatus
2. Also the transformation of dhatwagni
paka.
3. It is formed and transported through all
the Dhatuvaha srotas ( sira and dhamanis
including hridaya)
4. Where it permeates the entire body in
limbs and organs.
COMPOSITION OF OJAS
ACCORDING TO CHARAK
1. Colour – white or yellowish red or
colour of ghee.
2. Taste – sweet like honey
3. Smell – like fried paddy (Laja)
4. Other qualities – snigdha, guru,
picchila, mridu, sthira, shita,
sukshma(microscopic )
ACCORDING TO SUSHRUTA
AÉåeÉÈ xÉÉåqÉÉiqÉMÇü ÎxlÉakÉzÉÑYsÉÇ zÉÏiÉÇ
ÎxjÉUÇ xÉUqÉç ÌuÉÌuÉ£Çü qÉ×SÒ qÉÚixlÉÇ cÉ
mÉëÉhÉÉrÉiÉlÉqÉç E¨ÉqÉqÉç . (
xÉÑ.xÉÔ.15/21 )1. Soumya (watery in nature),
unctuousness, pure white in colour,
cold, stable, pervading, vivikta
(pure and clear), soft, mritsna
(delicate) and best supporter of life .
TYPES OF OJAS
1. PARA OJAS
2. APARA OJAS
Ojas marks the beginning of formation of embryo.
 ACCORDING TO CHAKRAPANI -
1. Para & Apara ojas are located in hridya.
2. It is ojas where the soul is lodged after the
union of the sukra and sonita .
3. The essence of the resultant sara i.e.
KALALA formed by the union of shukra
and shonita.
4. Entrance of ojas into the heart of the
embryo manifest the cardiac activities.
PARA OJAS
APARA OJAS
 ACCORDING TO VAGBHATA
1. Main function is Dehasthitinibandhanam,
 ACCORDING TO CHANDRANANDANA
1. It is protection of the body in all states.
2. Both words bala and ojas have been
used synonymously for Kapha.
3. They indicate the potential source of
strength.
ACCORDING TO CHARAK
1. The degenration and decay are the
natural characteristics of the human
body .
2. Even without any apparent causes of
Swabhavoparama.
3. Bala as the factor that controls the
doshas
4. And never allows them to produce
disease in the body.
PARINAMAN OF OJAS
mÉëjÉqÉåeÉÉrÉiÉåÌWûAÉåeÉÈzÉUÏUåÅÎxqÉlÉçzÉUÏËUhÉÉqÉç
|
(cÉ.xÉÔ. 17/75)
pÉëqÉUæÈTüsÉmÉÑwmÉåprÉÉårÉjÉÉxÉÇÍpÉërÉiÉåqÉkÉÑÈ|
iɲSÉåeÉÈzÉUÏUåprÉÉåaÉÑhÉæÈxÉÇÍpÉërÉiÉålÉ×hÉÉqÉç
(C.SU.17.74)
1. In the intrauterine life, Just like all
dhatu.
2. Ojas is also the product of dhatwagni
paka .
3. Nourished by the food or by the
nutrients derived from food .
ACCORDING TO CHARAK
1. Honey bees collect honey from
different varieties of flower &
Fruits and deposit at one place i.e.
WAX .
2. That the ojas is also collected from
all tissues of the body and
deposited in one place i.e. Hridaya.
Three Main stages
1. At the time of conception, essence
of the shukra and shonita.
2. In second stage, the essence of the
rasasara which provides nutrition
to the embryo.
3. In the third stage, when there is
formation of various organs, ojas
manifests its own actions.
QUALITIES OF OJAS
ACCORDING TO CHARAK
aÉÑÂzÉÏiÉÇ qÉ×SÒ zsɤhÉÇ oÉWûsÉÇ qÉkÉÑUÇ ÎxjÉUÇ
|
mÉëxɳÉÇ ÌmÉÎcNûsÉÇ ÎxlÉakÉqÉç AÉåeÉÉå SzÉaÉÑhÉÇ
xqÉÚiÉqÉç | (cÉ.ÍcÉ.24/31)
 Ojas has ten qualities - heavy ,
cold, softness, smoothness,
density, sweety, stable,
clearness, sliminess, and
unctuousness.
+ÉäVÉ: ºÉÉä¨ÉÉi¨ÉEÆú Ê×ÉMvÉÆ
¶ÉÖKÆú ¶ÉÒiÉÆκlÉ®Æ ºÉ®¨É **
Ê´ÉÊ´ÉHÆú¨ÉÞnÖü ¨ÉÞi×ÉÆSÉ
|ÉÉhÉɪÉiÉxɨÉÖkɨɨÉÂ**(S.SU.15.21)
 Watery in nature ,
unctuousness ,cold, stable,
pervading, Pure and Clear ,
Softness, Delicate, Best
support of life
PRAMAN OF OJAS
mÉëÉhÉÉ´ÉrÉxrÉAÉåeÉxÉÉåŹÉæ ÌoÉlSuÉÉå
WØûSrÉÉÍ´ÉiÉÉÈ CÌiÉ|
(cÉ.xÉÔ.30:11)
1. Apara ojas or Shleshmika ojas,
Present all over body .
2. Quantity – ½ Anjali.
3. Para ojas , present in hridaya and
considered as best supporter of life.
4. CHARAK - Quantity 8 drops
5. VAGBHATA - Quantity 6 drops
OJAKSHAYA KARANA
AÍpÉbÉÉiÉÉiÉç¤ÉrÉÉiÉç MüÉåmÉÉiÉç zÉÉåMüÉiÉç
krÉÉlÉÉiÉ´ÉqÉÉiÉç¤ÉÑkÉ:| AÉåeÉÈ xÉÇͤÉrÉiÉå ÌWû LãprÉÉå
kÉÉiÉÑaÉëWûhÉÌlÉÈxÉ×iÉqÉç xÉÑ.xÉÔ.15:23
1. Abhighata (Trauma)
2. Kshaya (Dhatukshaya due to disease)
3. Kopa (Anger)
4. Shoka (Grief)
5. Dhanya (Excessive thought and
anxiety)
6. Shrama (Fatigue)
7. Kshudha (Hunger)
OJAKSHAYA LAKSHANA
ÌoÉpÉåÌiÉ SÒoÉïsÉÉåÅpÉϤhÉÇ krÉÉrÉÌiÉ urÉÍjÉiÉåÎlSìrÉÈ|
SÑzNûÉrÉÉå SÒqÉïlÉɤÉÈ ¤ÉÉqÉÈ cÉLuÉ AÉåeÉxÉÈ
¤ÉrÉå || . (cÉ.xÉÔ.17:7)
 Excessive diminution of ojas in the body
gives rise to some signs and symptoms like
Bibheti (fearfullness)
1. Durbala – weakness and fatigue
2. Abhikshna dhyayati – worries too much
3. Vyathitendriya – affliction of indriyas with
pain and feeling of discomfort in the sense
organs.
CONTI.....
1.Dushcchaya- loss of complexion
2.Duramana – Imbalanced Mind
3.Ruksha – Dryness/ Roughness
of the body
4.Kshama – Emaciated/ thinness
ACCORDING TO SUSHRUTA
 Loss of ojas is of three varieties
1. Ojo visramasa – impairment of the
distribution of ojas to the dhatu or
tissues.
2. Ojo vyapat – change in or
modification of the natural properties
of ojas.
3. Ojo kshaya – loss and wasting of ojas
due to grief, anxiety wasting of dhatu
etc.
OJO VISRAMSA LAKSHANA
xÉÎlkÉÌuÉzsÉåwÉÉå aÉɧÉÉhÉÉÇ xÉSlÉÇ SÉåwÉcrÉuÉlÉÇ
Ì¢ürÉÉxÉͳÉUÉåkÉ: cÉ ÌuÉx§ÉÇxÉå | (xÉÑ.xÉÔ.ç15.24)
1. Sandhivislesha/ Sandhi Shlathana
(Looseness of the joint)
1. Gatrasada (Inertness of the body)
2. Doshachavana (Displacement of doshas
from their respective locations and
impairment in function)
3. Kriya – Sannnirodha (impairment of
activities of the body , include speech and
mind)
OJO VYAPAT LAKSHANA
xiÉokÉaÉÑÂaÉɧÉiÉÉ uÉÉiÉzÉÉåTüÉå uÉhÉïpÉåSÉå asÉÉÌlÉ:
iÉlSìÉ ÌlÉSìÉ cÉurÉÉmɳÉå | (xÉÑ.xÉÔ.ç15.24)
1. Stabdhagatrata ( Inertness of Body)
2. Gurugatrata (Heaviness of the body)
3. Vatashopha (General anasarca due to
vitiated vata )
4. Varnabheda (Change of complexion,
Pale colour)
CONTI......
5. Glani (Fatigue of the Senses)
6. Tandra (Drowsiness)
7. Nidra (Somnolence )
OJO KSHAYA LAKSHANA
qÉÔcNûÉï qÉÉÇxɤÉrÉå qÉÉåWû: mÉësÉÉmÉÉå
qÉUhÉqÉç CÌiÉ cÉ ¤ÉrÉå |
( xÉÑ.xÉÔ.ç
15.24)1.Murccha (loss of consciousness)
2.Mamsakshaya (Wasting of
Muscles)
3.Pralapa (Delirium)
4.Marana (death)
OJO VRIDDHI LAKSHANA
1. Increased state of ojas indicates
the increase of
Vyadhikshyamatwa Shakti .
2. That is Such person can resist any
disease.
3. A person with an increased state
of ojas is happy with strong dhatus
and capacity to do hard work .
VYADHIKSHAMATVA
lÉ cÉ xÉuÉÉïÍhÉ zÉUÏUÉÍhÉ urÉÉÍkɤÉqÉiuÉå xÉqÉjÉÉïÌlÉ
pÉuÉÎliÉ || (cÉ.xÉÔ.28/7)
1. The human body has the ability to resist almost
all types of organism or toxins .
2. That to damage the tissues or organs, leading to
causation of disease.
3. This capacity is known as Vyadhikshamatwa
Shakti.
ACCORDING TO CHARAK
All the dhatus (tissues ) are not
equally capable of
vyadhikshamatva.
 That is Capacity to resist the
disease.
ACCORDING TO CHAKRAPANI
 The human body Develops as a foetus
in the uterus of the mother after
union of the PUMBIJA and
STREEBIJA .
1. The tissues, organs and Parts of the
foetus (human body) develop.
2. And grow as planned by the
BIJABHAGA of pumbija and
streebija.
CLASSIFICATION OF
VYADHIKSHAMATVA
urÉÉÍkɤÉqÉiuÉÇ lÉÉqÉ urÉÉÍkÉoÉsÉÌuÉUÉåÍkÉiuÉÇ urÉÉÍkÉ
EimÉÉSmÉëÌiÉoÉlkÉMüiuÉqÉ CÌiÉ rÉÉuÉiÉç||
TWO TYPES -
1. Vyadhibala- Virodhitwa- which is
antagonist to the strength and
virulence of the disease
2. Vyadhyutpadapratibandhakatwa –
The capacity to inhibit, contain and
bind the causes or factors of disease.
BALA TYPES
ACCORDING TO CHARAK
1.Sahaja
2.Kalaja
3.Yuktikrita
SAHAJA (CONSTITUTIONAL)
1. Sahaja is constitutional.
2. It is present in each and every human
being from the very time of the birth
and received from the parent .
3. This is because of natural growth of
the dhatus in the body .
4. Thus the natural strength does not
require any extragenous factor for its
growth.
KALAJA
TWO TYPES –
1. RituRupa Kala - based upon season.
2. VayaRupa kala - based upon age.
The Year divided into two Ayanas
1. UTTARAYANA – Sishira, Vasant ,
Greeshma
2. DAKSHINAYANA – Varsha, Sharat
and Hemanta.
STRENGTH OF HUMAN
ACCORDING TO SEASON
SEASON STRENGTH
Greeshma &Varsha Completely depleted
Vasanta &Sharad Moderate strength
Hemanta &Shishira Full Strength
YUKTIKRITA (ACQUIRED)
1. This is achieved by the Proper
combination of diet and other
regimens.
2. Like rest, exercise, yoga.
3. Use of suitable Yoga.
4. The word Yoga is Aushadha Yoga .
5. It include Rasayana yoga,
Vaccination, inoculations and other
immunization method.
RASAYANA
1. Rasayana means Science of Lengthening
lifespan.
2. Rasayana therapy enriches rasa with
nutrients to help one attain longevity,
excellence in complexion and voice,
optimum development of physique.
3. Chawanprasha is one of the traditional
rasayanas. Other rasayanas like Pippali
Rasayana, Haritaki Rasayana etc.
ACCORDING TO MODERN
THE IMMUNE SYSTEM
CONTENTS
1. THE IMMUNE SYSTEM
2. BLOOD CELLS
3. THE IMMUNE RESPONSE
4. DEFENCE MECHANISM
5. PHAGOCYTOSIS
6. LYMPHOCYTES
7. ANTIBODY
8. HYPERSENSITIVITY
9. ALLERGY
10.REFERENCE
THE IMMUNE SYSTEM
 Immunology -
1. Study of the components and function of
the immune system
 Immune System -
A. Molecules, cells, tissues and organs
which provide non-specific and specific
protection against
a) Microorganisms
b) Microbial toxins
c) Tumor cells
BLOOD CELLS
THE IMMUNE RESPONSE
1. Immune response
A. Innate (non-specific)
B. Adaptive (specific)
I. Primary
II. Secondary
2. Immunity
A. State of non-specific and specific
protection
3. Acquisition of Immunity
I. Natural
II. Artificial
Figure 1-4
PHYSICAL BARRIER
DEFENSE MECHANISM OF THE
HUMAN HOST
1. Innate Mechanisms (Innate immunity)
a) First line of defense
b) Non-specific
2. Adaptive Mechanisms (Adaptive
immunity)
a) Second line of defense
b) Highly specific with memory
NATURAL ACQUIRED IMMUNITY
1. Active
A. Antigens enter body naturally with response
a) Innate and adaptive immune systems
b) Provides long term protection
2. Passive
A. Antibodies pass from mother to
a) Fetus across placenta
b) Infant in breast milk
ARTIFICIAL ACQUIRED IMMUNITY
1. Active
I. Antigens enter body through vaccination
with response of
a) Innate and adaptive immune systems
2. Passive
I. Antibodies from immune individuals injected
into body
 Referred to as
Immune serum globulins (ISG)
–Immunoglobulins (IG)
COLONY OF STREPTOCOCCUS BACTERIA
PHAGOCYTOSIS
PHAGOCYTES
1. Produced throughout life by the bone
marrow.
2. Scavengers – remove dead cells and
microorganisms.
NEUTROPHILS
• 60% of WBCs
• ‘Mobile tissues’ as they squeeze out of the
capillaries.
• Large numbers are released during
infections.
• Short lived – die after digesting bacteria.
• Dead neutrophils make up a large
proportion of pus.
MACROPHAGES
1. Larger than neutrophils.
2. Found in the organs, not the blood.
3. Made in bone marrow as monocytes,
called macrophages .
4. Long lived.
5. Initiate immune responses And
display antigens .
LYMPHOCYTES
1. Produce antibodies.
2. B-cells mature in bone marrow then
concentrate in lymph nodes and spleen.
3. T-cells mature in thymus gland.
4. B cells and T cells mature then circulate
in the blood and lymph .
5. Circulation ensures they come into contact
with pathogens and each other .
T – LYMPHOCYTES
1. Mature T-cells have T cell receptors which
have a very similar structure to antibodies
and are specific to particular antigen.
2. They are activated when the receptor comes
into contact with the Antigen with another
host cell
3. Ex. A macrophage membrane or an invaded
body cell. .
B – LYMPHOCYTES
1. Some activated B cells produce 
PLASMA CELLS.
2. These produce lots of antibodies <
1000/sec.
3. The antibodies travel to the blood, lymph,
lining of gut and lungs etc.
4. The number of plasma cells goes down
after a few weeks.
5. Antibodies stay in the blood longer.
6. Eventually their numbers go down too.
ANTIBODIES
1. Also known as Immunoglobulins.
2. They have heavy and light chains .
3. which are made up of polypeptides And
glycoprotein.
4. The chains are held together by disulphide
bridges.
5. Each antibody has two identical antigen
binding sites known as - variable regions.
6. The order of amino acids in the variable
regions determine the shape of the binding site.
WORK OF ANTIBODY
1. Some act as labels to identify the antigens for
phagocytes.
2. Some work as Antitoxins .
3. That is they block toxins of pathogen which
causing Cholera and tetanus.
4. Some attach to bacterial flagella making them
less active and easier for phagocytes to engulf.
5. Some cause Agglutination (clumping together)
of bacteria making them less likely to spread.
DIFFERENT
IMMUNOGLOBULINS
TYPES OF IMMUNOGLOBULINS
1. Five classes
a) Immunoglobulin A (IgA)
b) Immunoglobulin G (IgG)
c) Immunoglobulin M (IgM)
d) Immunoglobulin D (IgD)
e) Immunoglobulin E (IgE)
2. Based on structural differences in constant
regions of heavy chains
3. Classes have specialized effector functions
HYPERSENSITIVITY
1. The immunological hyersensitive reactions to
an agent give rise to various allergic condition
and autoimmune diseases.
TYPES
I. TYPE 1 – Anaphylactic Reactions
II. TYPE 2 - Cytotoxic Reactions
III. TYPE 3 - Antibody mediated Reactions
IV. TYPE 4 - Cell – mediated Reactions
V. TYPE 5 - Stimulatory/ Blocking Reactions
ALLERGY
1. The term allergy is used to describe an
OverReaction to substances in the environment
2. That are harmless for most people.
3. Induce an immune response that causes a
variety of symptoms in predisposed people.
4. ALLERGY is not a disease in the typical sense.
5. It is an exaggeration of the body’s natural
immune defenses.
6. Mild allergies can be annoying and severe
forms can be very serious or even deadly.
TYPES OF ALLERGY
1. RESPIRATORY ALLERGY
Allergic rhinoconjunctivitis,, rhinosinusitis &
Allergic asthma, which cause wheezing,
Coughing, shortness of breath, sneezing,
Rhinorrhea .
2. SKIN ALLERGY (DERMATITIS) :-
Atopic dermatitis (eczema) and contact
Dermatitis, which mainly cause skin rash.
3. OTHER ALLERGIES :-
Food allergies and insect venom, which cause
Different types of reactions that in some cases
May be life-threatening (anaphylaxis).
REFERENCES
1. CHARAK SAMHITA
2. SUSHRUTA SAMHITA
3. ASTANG HRIDAYAM GRANTHA
4. VD. RAJENDRA DESHPANDEY
5. DR. CHITARANJAN DAS
6. DR. SUBHASH RANADE
7. ESSENTIAL OF MEDICAL PHYSIOLOGY
(DR. SEMBULINGAM)
OJAS AND IMMUNITY

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OJAS AND IMMUNITY

  • 1. GUIDED BY DR. VAIDEHI RAOLE HOD DEPARTMENT OF KRIYA SHARIR PRESENTED BY DR. SUJIT KUMAR MD 1ST YEAR PARUL INSTITUTE OF AYURVED
  • 2. CONTENTS 1. NAAM AND NIRUKTI 2. PARYAYA 3. STHANA 4. COMPOSITION OF OJAS 5. TYPES OF OJAS 6. PARINAMAN OF OJAS 7. QUALITY OF OJAS 8. PRAMAN OF OJAS 9. OJAKSHAYA KARANA 10. OJAKSHAYA LAKSHANA 11. OJAVRIDDHI LAKSHANA 12. VYADHIKSHAMATVA 13. RASAYANA
  • 3. NAAM AND NIRUKTI AÉåeÉxiÉÑiÉåeÉÉåkÉÉiÉÑlÉÉÇzÉÑ¢üÉliÉÉlÉÉÇmÉUÇ xqÉ×iÉqÉç|A.WØû.xÉÔ.11.37 zÉÑ¢üxrÉxÉÉUqÉçAÉåeÉÈ|A.xÉ.zÉÉ.7/6 1. Ojas is the essence part of all the dhatu and is also mentioned as Bala. 2. Considered as updhatu & shleshmika dravya . 3. It is predominant of JALA and PRITHIVI Mahabhuta.
  • 4. PARYAYA 1. Sarva dhatu sara (Essence of all dhatu ) 2. Sthirata ( Stability ) 3. Sara (Essence ) 4. Prasad ( Qualitative substance ) 5. Jivashonitum ( Essence of life ) 6. Sleshma (Covering) 7. Deepti (Hunger ) 8. Kanti (Lusterness)
  • 5. CHARAK SUTRASTHAN MAHAT , DHARI, SARVA DHATU SNEHA CHARAK SUTRASTHAN UTAKRASHAT SARA, GHRITAVAN STHIRDHATU, BALA CHARAK RASA, PRAKRUTA SLESHMA SUSHRUTA PARAM TEJA ASHTANGA SANGRAHA SHUKRA SARA DALHANA BHARADI HARANA SHAKTI, JIVASHODITAM
  • 6. STHANA mÉëÉhÉÉ´ÉrÉxrÉ AÉåeÉxÉÉåŹÉæ ÌoÉlSuÉÉå WØûSrÉÉÍ´ÉiÉÉÈ CÌiÉ | AkÉÉïgeÉÍsÉ mÉËUÍqÉiÉxrÉ AÉåeÉxÉÉå kÉqÉlrÉ LuÉ WØûSrÉÉÍ´ÉiÉÉÈ xjÉÉlÉqÉç. (cÉ.xÉÔ.30:11) 1. Ojas is finest product of all the seven dhatus 2. Also the transformation of dhatwagni paka. 3. It is formed and transported through all the Dhatuvaha srotas ( sira and dhamanis including hridaya) 4. Where it permeates the entire body in limbs and organs.
  • 7. COMPOSITION OF OJAS ACCORDING TO CHARAK 1. Colour – white or yellowish red or colour of ghee. 2. Taste – sweet like honey 3. Smell – like fried paddy (Laja) 4. Other qualities – snigdha, guru, picchila, mridu, sthira, shita, sukshma(microscopic )
  • 8. ACCORDING TO SUSHRUTA AÉåeÉÈ xÉÉåqÉÉiqÉMÇü ÎxlÉakÉzÉÑYsÉÇ zÉÏiÉÇ ÎxjÉUÇ xÉUqÉç ÌuÉÌuÉ£Çü qÉ×SÒ qÉÚixlÉÇ cÉ mÉëÉhÉÉrÉiÉlÉqÉç E¨ÉqÉqÉç . ( xÉÑ.xÉÔ.15/21 )1. Soumya (watery in nature), unctuousness, pure white in colour, cold, stable, pervading, vivikta (pure and clear), soft, mritsna (delicate) and best supporter of life .
  • 9. TYPES OF OJAS 1. PARA OJAS 2. APARA OJAS
  • 10. Ojas marks the beginning of formation of embryo.  ACCORDING TO CHAKRAPANI - 1. Para & Apara ojas are located in hridya. 2. It is ojas where the soul is lodged after the union of the sukra and sonita . 3. The essence of the resultant sara i.e. KALALA formed by the union of shukra and shonita. 4. Entrance of ojas into the heart of the embryo manifest the cardiac activities. PARA OJAS
  • 11. APARA OJAS  ACCORDING TO VAGBHATA 1. Main function is Dehasthitinibandhanam,  ACCORDING TO CHANDRANANDANA 1. It is protection of the body in all states. 2. Both words bala and ojas have been used synonymously for Kapha. 3. They indicate the potential source of strength.
  • 12. ACCORDING TO CHARAK 1. The degenration and decay are the natural characteristics of the human body . 2. Even without any apparent causes of Swabhavoparama. 3. Bala as the factor that controls the doshas 4. And never allows them to produce disease in the body.
  • 13. PARINAMAN OF OJAS mÉëjÉqÉåeÉÉrÉiÉåÌWûAÉåeÉÈzÉUÏUåÅÎxqÉlÉçzÉUÏËUhÉÉqÉç | (cÉ.xÉÔ. 17/75) pÉëqÉUæÈTüsÉmÉÑwmÉåprÉÉårÉjÉÉxÉÇÍpÉërÉiÉåqÉkÉÑÈ| iɲSÉåeÉÈzÉUÏUåprÉÉåaÉÑhÉæÈxÉÇÍpÉërÉiÉålÉ×hÉÉqÉç (C.SU.17.74) 1. In the intrauterine life, Just like all dhatu. 2. Ojas is also the product of dhatwagni paka . 3. Nourished by the food or by the nutrients derived from food .
  • 14. ACCORDING TO CHARAK 1. Honey bees collect honey from different varieties of flower & Fruits and deposit at one place i.e. WAX . 2. That the ojas is also collected from all tissues of the body and deposited in one place i.e. Hridaya.
  • 15. Three Main stages 1. At the time of conception, essence of the shukra and shonita. 2. In second stage, the essence of the rasasara which provides nutrition to the embryo. 3. In the third stage, when there is formation of various organs, ojas manifests its own actions.
  • 16. QUALITIES OF OJAS ACCORDING TO CHARAK aÉÑÂzÉÏiÉÇ qÉ×SÒ zsɤhÉÇ oÉWûsÉÇ qÉkÉÑUÇ ÎxjÉUÇ | mÉëxɳÉÇ ÌmÉÎcNûsÉÇ ÎxlÉakÉqÉç AÉåeÉÉå SzÉaÉÑhÉÇ xqÉÚiÉqÉç | (cÉ.ÍcÉ.24/31)  Ojas has ten qualities - heavy , cold, softness, smoothness, density, sweety, stable, clearness, sliminess, and unctuousness.
  • 17. +ÉäVÉ: ºÉÉä¨ÉÉi¨ÉEÆú Ê×ÉMvÉÆ ¶ÉÖKÆú ¶ÉÒiÉÆκlÉ®Æ ºÉ®¨É ** Ê´ÉÊ´ÉHÆú¨ÉÞnÖü ¨ÉÞi×ÉÆSÉ |ÉÉhÉɪÉiÉxɨÉÖkɨɨÉÂ**(S.SU.15.21)  Watery in nature , unctuousness ,cold, stable, pervading, Pure and Clear , Softness, Delicate, Best support of life
  • 18. PRAMAN OF OJAS mÉëÉhÉÉ´ÉrÉxrÉAÉåeÉxÉÉåŹÉæ ÌoÉlSuÉÉå WØûSrÉÉÍ´ÉiÉÉÈ CÌiÉ| (cÉ.xÉÔ.30:11) 1. Apara ojas or Shleshmika ojas, Present all over body . 2. Quantity – ½ Anjali. 3. Para ojas , present in hridaya and considered as best supporter of life. 4. CHARAK - Quantity 8 drops 5. VAGBHATA - Quantity 6 drops
  • 19. OJAKSHAYA KARANA AÍpÉbÉÉiÉÉiÉç¤ÉrÉÉiÉç MüÉåmÉÉiÉç zÉÉåMüÉiÉç krÉÉlÉÉiÉ´ÉqÉÉiÉç¤ÉÑkÉ:| AÉåeÉÈ xÉÇͤÉrÉiÉå ÌWû LãprÉÉå kÉÉiÉÑaÉëWûhÉÌlÉÈxÉ×iÉqÉç xÉÑ.xÉÔ.15:23 1. Abhighata (Trauma) 2. Kshaya (Dhatukshaya due to disease) 3. Kopa (Anger) 4. Shoka (Grief) 5. Dhanya (Excessive thought and anxiety) 6. Shrama (Fatigue) 7. Kshudha (Hunger)
  • 20. OJAKSHAYA LAKSHANA ÌoÉpÉåÌiÉ SÒoÉïsÉÉåÅpÉϤhÉÇ krÉÉrÉÌiÉ urÉÍjÉiÉåÎlSìrÉÈ| SÑzNûÉrÉÉå SÒqÉïlÉɤÉÈ ¤ÉÉqÉÈ cÉLuÉ AÉåeÉxÉÈ ¤ÉrÉå || . (cÉ.xÉÔ.17:7)  Excessive diminution of ojas in the body gives rise to some signs and symptoms like Bibheti (fearfullness) 1. Durbala – weakness and fatigue 2. Abhikshna dhyayati – worries too much 3. Vyathitendriya – affliction of indriyas with pain and feeling of discomfort in the sense organs.
  • 21. CONTI..... 1.Dushcchaya- loss of complexion 2.Duramana – Imbalanced Mind 3.Ruksha – Dryness/ Roughness of the body 4.Kshama – Emaciated/ thinness
  • 22. ACCORDING TO SUSHRUTA  Loss of ojas is of three varieties 1. Ojo visramasa – impairment of the distribution of ojas to the dhatu or tissues. 2. Ojo vyapat – change in or modification of the natural properties of ojas. 3. Ojo kshaya – loss and wasting of ojas due to grief, anxiety wasting of dhatu etc.
  • 23. OJO VISRAMSA LAKSHANA xÉÎlkÉÌuÉzsÉåwÉÉå aÉɧÉÉhÉÉÇ xÉSlÉÇ SÉåwÉcrÉuÉlÉÇ Ì¢ürÉÉxÉͳÉUÉåkÉ: cÉ ÌuÉx§ÉÇxÉå | (xÉÑ.xÉÔ.ç15.24) 1. Sandhivislesha/ Sandhi Shlathana (Looseness of the joint) 1. Gatrasada (Inertness of the body) 2. Doshachavana (Displacement of doshas from their respective locations and impairment in function) 3. Kriya – Sannnirodha (impairment of activities of the body , include speech and mind)
  • 24. OJO VYAPAT LAKSHANA xiÉokÉaÉÑÂaÉɧÉiÉÉ uÉÉiÉzÉÉåTüÉå uÉhÉïpÉåSÉå asÉÉÌlÉ: iÉlSìÉ ÌlÉSìÉ cÉurÉÉmɳÉå | (xÉÑ.xÉÔ.ç15.24) 1. Stabdhagatrata ( Inertness of Body) 2. Gurugatrata (Heaviness of the body) 3. Vatashopha (General anasarca due to vitiated vata ) 4. Varnabheda (Change of complexion, Pale colour)
  • 25. CONTI...... 5. Glani (Fatigue of the Senses) 6. Tandra (Drowsiness) 7. Nidra (Somnolence )
  • 26. OJO KSHAYA LAKSHANA qÉÔcNûÉï qÉÉÇxɤÉrÉå qÉÉåWû: mÉësÉÉmÉÉå qÉUhÉqÉç CÌiÉ cÉ ¤ÉrÉå | ( xÉÑ.xÉÔ.ç 15.24)1.Murccha (loss of consciousness) 2.Mamsakshaya (Wasting of Muscles) 3.Pralapa (Delirium) 4.Marana (death)
  • 27. OJO VRIDDHI LAKSHANA 1. Increased state of ojas indicates the increase of Vyadhikshyamatwa Shakti . 2. That is Such person can resist any disease. 3. A person with an increased state of ojas is happy with strong dhatus and capacity to do hard work .
  • 28. VYADHIKSHAMATVA lÉ cÉ xÉuÉÉïÍhÉ zÉUÏUÉÍhÉ urÉÉÍkɤÉqÉiuÉå xÉqÉjÉÉïÌlÉ pÉuÉÎliÉ || (cÉ.xÉÔ.28/7) 1. The human body has the ability to resist almost all types of organism or toxins . 2. That to damage the tissues or organs, leading to causation of disease. 3. This capacity is known as Vyadhikshamatwa Shakti.
  • 29. ACCORDING TO CHARAK All the dhatus (tissues ) are not equally capable of vyadhikshamatva.  That is Capacity to resist the disease.
  • 30. ACCORDING TO CHAKRAPANI  The human body Develops as a foetus in the uterus of the mother after union of the PUMBIJA and STREEBIJA . 1. The tissues, organs and Parts of the foetus (human body) develop. 2. And grow as planned by the BIJABHAGA of pumbija and streebija.
  • 31. CLASSIFICATION OF VYADHIKSHAMATVA urÉÉÍkɤÉqÉiuÉÇ lÉÉqÉ urÉÉÍkÉoÉsÉÌuÉUÉåÍkÉiuÉÇ urÉÉÍkÉ EimÉÉSmÉëÌiÉoÉlkÉMüiuÉqÉ CÌiÉ rÉÉuÉiÉç|| TWO TYPES - 1. Vyadhibala- Virodhitwa- which is antagonist to the strength and virulence of the disease 2. Vyadhyutpadapratibandhakatwa – The capacity to inhibit, contain and bind the causes or factors of disease.
  • 32. BALA TYPES ACCORDING TO CHARAK 1.Sahaja 2.Kalaja 3.Yuktikrita
  • 33. SAHAJA (CONSTITUTIONAL) 1. Sahaja is constitutional. 2. It is present in each and every human being from the very time of the birth and received from the parent . 3. This is because of natural growth of the dhatus in the body . 4. Thus the natural strength does not require any extragenous factor for its growth.
  • 34. KALAJA TWO TYPES – 1. RituRupa Kala - based upon season. 2. VayaRupa kala - based upon age. The Year divided into two Ayanas 1. UTTARAYANA – Sishira, Vasant , Greeshma 2. DAKSHINAYANA – Varsha, Sharat and Hemanta.
  • 35. STRENGTH OF HUMAN ACCORDING TO SEASON SEASON STRENGTH Greeshma &Varsha Completely depleted Vasanta &Sharad Moderate strength Hemanta &Shishira Full Strength
  • 36. YUKTIKRITA (ACQUIRED) 1. This is achieved by the Proper combination of diet and other regimens. 2. Like rest, exercise, yoga. 3. Use of suitable Yoga. 4. The word Yoga is Aushadha Yoga . 5. It include Rasayana yoga, Vaccination, inoculations and other immunization method.
  • 37. RASAYANA 1. Rasayana means Science of Lengthening lifespan. 2. Rasayana therapy enriches rasa with nutrients to help one attain longevity, excellence in complexion and voice, optimum development of physique. 3. Chawanprasha is one of the traditional rasayanas. Other rasayanas like Pippali Rasayana, Haritaki Rasayana etc.
  • 38. ACCORDING TO MODERN THE IMMUNE SYSTEM
  • 39. CONTENTS 1. THE IMMUNE SYSTEM 2. BLOOD CELLS 3. THE IMMUNE RESPONSE 4. DEFENCE MECHANISM 5. PHAGOCYTOSIS 6. LYMPHOCYTES 7. ANTIBODY 8. HYPERSENSITIVITY 9. ALLERGY 10.REFERENCE
  • 40. THE IMMUNE SYSTEM  Immunology - 1. Study of the components and function of the immune system  Immune System - A. Molecules, cells, tissues and organs which provide non-specific and specific protection against a) Microorganisms b) Microbial toxins c) Tumor cells
  • 42. THE IMMUNE RESPONSE 1. Immune response A. Innate (non-specific) B. Adaptive (specific) I. Primary II. Secondary 2. Immunity A. State of non-specific and specific protection 3. Acquisition of Immunity I. Natural II. Artificial
  • 44. DEFENSE MECHANISM OF THE HUMAN HOST 1. Innate Mechanisms (Innate immunity) a) First line of defense b) Non-specific 2. Adaptive Mechanisms (Adaptive immunity) a) Second line of defense b) Highly specific with memory
  • 45. NATURAL ACQUIRED IMMUNITY 1. Active A. Antigens enter body naturally with response a) Innate and adaptive immune systems b) Provides long term protection 2. Passive A. Antibodies pass from mother to a) Fetus across placenta b) Infant in breast milk
  • 46. ARTIFICIAL ACQUIRED IMMUNITY 1. Active I. Antigens enter body through vaccination with response of a) Innate and adaptive immune systems 2. Passive I. Antibodies from immune individuals injected into body  Referred to as Immune serum globulins (ISG) –Immunoglobulins (IG)
  • 49.
  • 50. PHAGOCYTES 1. Produced throughout life by the bone marrow. 2. Scavengers – remove dead cells and microorganisms.
  • 51. NEUTROPHILS • 60% of WBCs • ‘Mobile tissues’ as they squeeze out of the capillaries. • Large numbers are released during infections. • Short lived – die after digesting bacteria. • Dead neutrophils make up a large proportion of pus.
  • 52. MACROPHAGES 1. Larger than neutrophils. 2. Found in the organs, not the blood. 3. Made in bone marrow as monocytes, called macrophages . 4. Long lived. 5. Initiate immune responses And display antigens .
  • 53. LYMPHOCYTES 1. Produce antibodies. 2. B-cells mature in bone marrow then concentrate in lymph nodes and spleen. 3. T-cells mature in thymus gland. 4. B cells and T cells mature then circulate in the blood and lymph . 5. Circulation ensures they come into contact with pathogens and each other .
  • 54.
  • 55. T – LYMPHOCYTES 1. Mature T-cells have T cell receptors which have a very similar structure to antibodies and are specific to particular antigen. 2. They are activated when the receptor comes into contact with the Antigen with another host cell 3. Ex. A macrophage membrane or an invaded body cell. .
  • 56. B – LYMPHOCYTES 1. Some activated B cells produce  PLASMA CELLS. 2. These produce lots of antibodies < 1000/sec. 3. The antibodies travel to the blood, lymph, lining of gut and lungs etc. 4. The number of plasma cells goes down after a few weeks. 5. Antibodies stay in the blood longer. 6. Eventually their numbers go down too.
  • 57.
  • 58. ANTIBODIES 1. Also known as Immunoglobulins. 2. They have heavy and light chains . 3. which are made up of polypeptides And glycoprotein. 4. The chains are held together by disulphide bridges. 5. Each antibody has two identical antigen binding sites known as - variable regions. 6. The order of amino acids in the variable regions determine the shape of the binding site.
  • 59. WORK OF ANTIBODY 1. Some act as labels to identify the antigens for phagocytes. 2. Some work as Antitoxins . 3. That is they block toxins of pathogen which causing Cholera and tetanus. 4. Some attach to bacterial flagella making them less active and easier for phagocytes to engulf. 5. Some cause Agglutination (clumping together) of bacteria making them less likely to spread.
  • 61. TYPES OF IMMUNOGLOBULINS 1. Five classes a) Immunoglobulin A (IgA) b) Immunoglobulin G (IgG) c) Immunoglobulin M (IgM) d) Immunoglobulin D (IgD) e) Immunoglobulin E (IgE) 2. Based on structural differences in constant regions of heavy chains 3. Classes have specialized effector functions
  • 62. HYPERSENSITIVITY 1. The immunological hyersensitive reactions to an agent give rise to various allergic condition and autoimmune diseases. TYPES I. TYPE 1 – Anaphylactic Reactions II. TYPE 2 - Cytotoxic Reactions III. TYPE 3 - Antibody mediated Reactions IV. TYPE 4 - Cell – mediated Reactions V. TYPE 5 - Stimulatory/ Blocking Reactions
  • 63. ALLERGY 1. The term allergy is used to describe an OverReaction to substances in the environment 2. That are harmless for most people. 3. Induce an immune response that causes a variety of symptoms in predisposed people. 4. ALLERGY is not a disease in the typical sense. 5. It is an exaggeration of the body’s natural immune defenses. 6. Mild allergies can be annoying and severe forms can be very serious or even deadly.
  • 64. TYPES OF ALLERGY 1. RESPIRATORY ALLERGY Allergic rhinoconjunctivitis,, rhinosinusitis & Allergic asthma, which cause wheezing, Coughing, shortness of breath, sneezing, Rhinorrhea . 2. SKIN ALLERGY (DERMATITIS) :- Atopic dermatitis (eczema) and contact Dermatitis, which mainly cause skin rash. 3. OTHER ALLERGIES :- Food allergies and insect venom, which cause Different types of reactions that in some cases May be life-threatening (anaphylaxis).
  • 65. REFERENCES 1. CHARAK SAMHITA 2. SUSHRUTA SAMHITA 3. ASTANG HRIDAYAM GRANTHA 4. VD. RAJENDRA DESHPANDEY 5. DR. CHITARANJAN DAS 6. DR. SUBHASH RANADE 7. ESSENTIAL OF MEDICAL PHYSIOLOGY (DR. SEMBULINGAM)