Introduction of nutraceuticals with formulation and its benifits some marketed nutraceuticals law governing to nutraceuticals

1. NUTRACEUTICALS
MADE BY:
SUDHANSHU MISHRA
M.PHARMA
PHARMACEUTICS
RAJEEV GANDHI TECHNICAL UNIVERSITY
BHOPAL
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2. CONTENTS
 DEFINATION
 BENEFITS OF NUTRACEUTICALS
 CLASSIFICATION
 PROBIOTICS
 PREBIOTICS
 DIETARY FIBRES
 ANTIOXIDANTS
 LAW GOVERNING NUTACEUTICALS IN INDIA
 AREA COVEREDBY NUTACEUTICALS
 NUTACEUTICAL MARKET
 EXAMPLES OF NUTRACEUTICALS AVAILABLE IN MARKET
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3. DEFINITION-
 The term nutraceutical was coined by “Stephen Defelice”
 NEUTRACEUTICAL is any substance that is a food or part of
food and provides medical or health benefits, including the
prevention and treatment of disease.
 The functional component of the food must be standardized in
the nutraceutical produced under good manufacturing
practices (GMPs).
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4. NUTRITION REQUIRED FOR
HEALTH
PHARMACEUTICALS
REMEDY FOR
SICKNESS/INJURY
NUTRACEUTICALS
PREVENTATIVE
MEDICALAPPROACH
Figure: Concept of Nutraceuticals
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5. BENEFITS OF
NEUTRACEUTICALS- May increase the health value of our diet.
 May help us to live longer.
 May help us to avoid particular medical conditions.
 May have a psychological benefit from doing something for
oneself.
 May present food for population with special needs.
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6. CLASSIFICATION
Neutraceuticals can be classified based on-
 NATURAL SOURCE/FOOD SOURCE
 PHARMACOLOGICAL CONDITIONS
 CHEMICAL CONDITION
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7. Classification Based On Source-
 PLANT- Tomato,momordica
 Animal- Shark liver oil, codeliver oil
 Minerals- Calcium,magnesium,phosphorous
 Micro-organism- Bifidobacterium,lactobacilli
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8. Classification Based On
Pharmacological action
 Akkergy relief- Ginko biloba
 Arthritis support- Glucosaamine
 Cancer prevention- Flax seed, Green tea
 Cardiac disease- Garlic
 Digestive support- Digestive enzyme
 Diabetic support- Momordica
 Immunomodulators- Ginseng
 Prostate support-Tomato lycopene
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9. Classification Based Chemical Nature-
 ISOPRENOIDS- Carotinoids, Saponin, Simple Terpine
 PHENOLIC COMPOUND- Coumarins,Tannins, Lignin,
Flavonones
 PROTIEN- Aminoacids, Indole, Folate, Choline
 CARBOHYDRATE AND DERIVATIVES- Ascorbic acid,
Oligosaccharides
 MINERALS- Calcium, Selenium, Zinc
 MICROBIAL-Probiotics, Prebiotic
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10. Classification Based On Chemical
Groups
S. NO CLASS EXAMPLES
1. Inorganic mineral supplement Minerals
2. Probiotics Helpful bacteria
3. Prebiotics Digestive enzyme
4. Antioxidant Natural antioxidant
5. Phytochemicals
Fatty acids Omega 3 fatty acids
Phenolics Tea polyphenol
Lipids Sphingolipis
Protien Soyaprotein
6. Herbs Methi,flax seed
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11. Probiotics-
Live microorganisms which, when
administered in adequate amount, confer a health benefit on the
host.
 Species of Lactobacillus
 Bifidobacterium
 Yeast Saccharomyces cerevisiae
 Some E.coli and Bacillus species are also used as probiotics
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12. Prebiotics-
Non digestablesubstances that providea
beneficial physiological effect for the host by selectively
stimulating the favorable growth of a limited number of
indigenous bacteria.
Commonly known prebiotics are-
 Oligofructose
 Insulin
 Galacto-oligosaccharides
 Lactulose
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13. Dietary fibres-
Dietaryfibers are of two type-
 Water insoluble fibers
 Water soluble fibers
Daily recommended intakeis 30-40gms.
Sources:
 Whole graincereals, Wheat product
 Oats,dried beans, legumes
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14. Antioxidant-
Antioxidant are of 3 categories-
 True antioxidant
 Reducing agent
 Antioxidant synergists
Deficiency causes disease like cancer, rheumatoid
arthritis,Alzheimer disease, cardiovascular disease.
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15. Nutraceutical Regulation In INDIA-
 Nutraceuticals and fuctional food in the recent years have
witnessed a tremendous increase in the interest among the
consumers due to their potentialof providing health benefits.
 INDIA is the second largest producer of the food. Although,
there were multiple laws and regulations covering the food in
india,but there was no single law that could have significantly
regulated the functional food.
 IN 2006,the Indian government passed food safety and
standard act to integrate and streamline the many regulations
covering nutraceuticals, food and dietary supplement.
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16. • The new regulation ,food safety and standards for food health
supplements,nutraceuticals, food for special dietary
use,functional food and normal food regulation 2016,is based on
and framed from section 22 of the food and safety act that
provides-
1.General conditions for the manufacturing and sale of
Nutraceuticals,food supplement etc.
2. Various schedule dealing with vitamins,minerals,list of plant
ingredient as well comprehensive schedule of additives which is
further divided into various sub categories.
3. Comprehensive rules for themanufacturing and sales of food
for special healthsupplement,nutraceuticals,special dietary use
and normal food.
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17. Area covered by Nutraceutials-
 Anti- arthritis
 Sleeping disorder
 Digestion problem
 Osteoorosis
 Cholestrol lowering
 Diabetes
 Prevetion of certain cancer
 Blood pressure
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18. NUTRACEUTICAL MARKET-
 The global nutraceuticals market is divided into the following
categories:
 Functional food
 Functional beverage
 Dietary supplement
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19. EXAMPLE OF NUTRACEUTICALS
CURRENTALY AVAILABLEIN
MARKET- VITAMIN ANDMINERAL SUPPLEMENTS;
eg- VitaminA(Beta-carotene)
 ADDITIONAL SUPPLEMENTS:
eg- cod liver oil,primroseoil, glucosamine, garlic etc.
 SPORTS PRODUCT:
eg-Glucon-D
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20. CONCLUSION-
 Nutraceuticals are presentin most of the food ingredient with
varying concentration.
 Concentration,time and duration of supply of nutraceuticals
influence human health.
 Manupulating the food,concentration of active ingredient can
be increased.
 Diet rich in nutraceuticals along with regular exercise,stress
reduction and maintenance of healthy body weight will
maximum and reduce disease risk.
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