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Prepared by:
Shorouq Alhoutary
• Under normal conditions, most
water intake is due NOT to thirst but
to
• social factors
• cultural factors
• (e.g. drinking with meals or at
work breaks, water in food)
Fluid Physiology
‘’Thirst’’
‘’Thirst’’
How do we feel
thirsty?
There are 4
stimuli for thirst
Hypertonicity
Hypertonicity
Hypovolaemia
Hypertonicity
Hypovolaemia
Hypotension
Hypertonicity
Hypovolaemia
Hypotension
Angiotensin II
I. Hypertonicity
• Higher concentration of
solutes outside the cell
than inside the cell —>
cellular dehydration
• Causes:
• High sodium diet
II. Hypovolaemia
• Decreased blood volume;
more specifically, decrease
in volume of blood plasma
(ICF volume is decreased)
• Causes:
• Haemorrhage
III. Hypotension
• = low blood pressure
• Causes:
• Pregnancy
• Heart problems
• Endocrine problems
• Haemorrhage
• Dehydration .. etc
VI. Angiotensin II
Hypertonicity
Osmorec
eptors
in the
hypothala
mus
Hypertonicity
Hypovolaemia
Osmorec
eptors
in the
hypothala
mus
Low
pressure
baroreceptor
s in the great
veins and
right atrium
Hypertonicity
Hypovolaemia
Hypotension
Osmorec
eptors
in the
hypothala
mus
Low
pressure
baroreceptor
s in the great
veins and
right atrium
High
pressure
baroreceptor
s in carotid
sinus & aorta
Hypertonicity
Hypovolaemia
Hypotension
Angiotensin II
Osmorec
eptors
in the
hypothala
mus
Low
pressure
baroreceptor
s in the great
veins and
right atrium
High
pressure
baroreceptor
s in carotid
sinus & aorta
consequent to
the release of
renin by the
kidney (in
response to
renal
hypotension)
In
Summary ..
Thank You…
Any Question?
Thank You..

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Physiology of thirst