2. Introduction:
It is a long-term, progressive, and
disabling autoimmune disease.
It causes inflammation, swelling, and
pain in and around the joints and other
body organs.
It is a chronic inflammatory disease.
It also affect the skin, lungs, blood vessel.
Moreover, it affects the women than men.
5. SYMPTOMS:
Tender, warm, swollen joints
Joint stiffness that is usually worse in the
mornings and after inactivity
Fatigue
6.
7. Clinical categories:
Seropositive:
Patients have anticyclic cittrullinated
peptides(anti-CCP).
These are the ab that produces RA
symptoms.
The presence these antibodies detected 5-
10 years before clinical RA symptoms appear.
8. Seronegative:
Patients develop RA even in the absence of
antibodies in their blood.
Patients those who show negative result for
anti – CCP.
Though it’s possible for seronegative patients
to have milder rheumatoid arthritis symptoms
than seropositive patients.
Many seronegative patients may not respond
to typical rheumatoid arthritis treatments.
9. Juvenile Rheumatoid Arthritis:
It is another type, that affects patients
under the age of 17 years old.
It is diagnosed from a series of different
blood tests including testing for
rheumatoid factor and the presence of
anti-CCPs.
Doctors may not be able to detect
abnormalities in the blood tests of
children.
