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THE ROLE OF ANTIBIOTICS RESISTANCE IN
THE ERADICATION AND CONTROL OF
EPIDEMICS
BY
ADAM ROFIAT 20HSM063
SUPERVISOR
MR. ADEOTI O.M
INTRODUCTION
MEANING OF ANTIBIOTICS MEANING OF RESITANCES
This is a medicine (such as
penicillin or its derivates) that
inhibits the growth of or
destroys microorganisms
This is the capacity of bacteria
to withstand the effects of a
harmful chemical agents
1. Limiting uptake of a drug 2. Modifying a drug target
3. Inactivating a drug 4. Active drug efflux
FOUR CATEGORIES OF ANTIBIOTICS RESISTANCE
2
AIM AND OBJECTIVES OF ANTIBIOTICS RESISTANCE
AIM OF ANTIBIOTICS RESISTANCE
OBJECTIVE OF ANTIBIOTICS RESISTANCE
The aim is to strengthen surveillance and research
The objective includes;
1. To reduce the incidence of infections
2. To optimize the use of antimicrobial
medicines
3. To ensure sustainable investment in
countering antimicrobial resistance
3
DEVELOPMENT OF RESISTANCE
These antibiotics do destroy the normal flora.
Opportunistic pathogens that are resistant survive and can take hold.
Causes and Consequences
Results from misuse, overuse, under/ inadequate useof
antimicrobials
> Costs money, lives and undermines effectiveness of health delivery
programs
> Major future threat to regional, global political stability and national
security
4
WHY ARE ANTIBIOTICS AND ANTIMICROBIAL
RESISTANCE IMPORTANT?
 Antibiotics treat infections caused by bacteria
 Modern medicine, especially surgery and cancer treatments, depends on effective
antibiotics to minimise the risk of infection
− Currently, antibiotics reduce post-operative infection rates to below 2%
− Without effective antibiotics, this could increase to around 40% to 50%. Up to 30% of
these patients could die from resistant bacterial infections
− The risk of mortality without access to effective antibiotics may make some treatments
and surgical procedures too risky to continue
 Antimicrobial resistance results in substantial financial cost for patients and
healthcare systems.
5
6
Antibiotics are a unique medicine
 In general, the impact of medications are limited to the
patient taking them
 Use of antibiotics has an impact not just for the patient
using them but the global community as well
7
8
Where do we use
antibiotics?
 Humans
 Community
 Hospital
 Animals
 Pets
 Livestock
 Agriculture
 Crops
 Aquaculture
USA
UK
9
10
CONCLUSION
Clinical guidelines, direct education and regular
reports on antibiogram may contribute to more
prudent use of antibiotics. Overall, the problem of
antibiotics resistance is global. However, measures
need to be taken at an individual, institutional and
ultimately at national healthcare level.
11
RECOMMENDATION
This is to recommend that we should ensure a robust
national action plan to tackle antibiotics resistance is in
place. Improve surveillance of antibiotics resistance
infections. Strengthen policies, programmes and
implementation of infection prevention and cpntrol
measures. Regulate and promote the appropriate use and
disposal of quality medicines.
12
THANK YOU
FOR YOUR
ATTENTION
13

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ANTIBIOTICS RESISTANCE.pptx

  • 1. THE ROLE OF ANTIBIOTICS RESISTANCE IN THE ERADICATION AND CONTROL OF EPIDEMICS BY ADAM ROFIAT 20HSM063 SUPERVISOR MR. ADEOTI O.M
  • 2. INTRODUCTION MEANING OF ANTIBIOTICS MEANING OF RESITANCES This is a medicine (such as penicillin or its derivates) that inhibits the growth of or destroys microorganisms This is the capacity of bacteria to withstand the effects of a harmful chemical agents 1. Limiting uptake of a drug 2. Modifying a drug target 3. Inactivating a drug 4. Active drug efflux FOUR CATEGORIES OF ANTIBIOTICS RESISTANCE 2
  • 3. AIM AND OBJECTIVES OF ANTIBIOTICS RESISTANCE AIM OF ANTIBIOTICS RESISTANCE OBJECTIVE OF ANTIBIOTICS RESISTANCE The aim is to strengthen surveillance and research The objective includes; 1. To reduce the incidence of infections 2. To optimize the use of antimicrobial medicines 3. To ensure sustainable investment in countering antimicrobial resistance 3
  • 4. DEVELOPMENT OF RESISTANCE These antibiotics do destroy the normal flora. Opportunistic pathogens that are resistant survive and can take hold. Causes and Consequences Results from misuse, overuse, under/ inadequate useof antimicrobials > Costs money, lives and undermines effectiveness of health delivery programs > Major future threat to regional, global political stability and national security 4
  • 5. WHY ARE ANTIBIOTICS AND ANTIMICROBIAL RESISTANCE IMPORTANT?  Antibiotics treat infections caused by bacteria  Modern medicine, especially surgery and cancer treatments, depends on effective antibiotics to minimise the risk of infection − Currently, antibiotics reduce post-operative infection rates to below 2% − Without effective antibiotics, this could increase to around 40% to 50%. Up to 30% of these patients could die from resistant bacterial infections − The risk of mortality without access to effective antibiotics may make some treatments and surgical procedures too risky to continue  Antimicrobial resistance results in substantial financial cost for patients and healthcare systems. 5
  • 6. 6
  • 7. Antibiotics are a unique medicine  In general, the impact of medications are limited to the patient taking them  Use of antibiotics has an impact not just for the patient using them but the global community as well 7
  • 8. 8
  • 9. Where do we use antibiotics?  Humans  Community  Hospital  Animals  Pets  Livestock  Agriculture  Crops  Aquaculture USA UK 9
  • 10. 10
  • 11. CONCLUSION Clinical guidelines, direct education and regular reports on antibiogram may contribute to more prudent use of antibiotics. Overall, the problem of antibiotics resistance is global. However, measures need to be taken at an individual, institutional and ultimately at national healthcare level. 11
  • 12. RECOMMENDATION This is to recommend that we should ensure a robust national action plan to tackle antibiotics resistance is in place. Improve surveillance of antibiotics resistance infections. Strengthen policies, programmes and implementation of infection prevention and cpntrol measures. Regulate and promote the appropriate use and disposal of quality medicines. 12