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PARTNER.
INNOVATE.
DELIVER.
SIMCRO GENERAL PRESENTATION

2012




www.simcro.com
PAGE 1




YOUR ACCOUNT MANAGER
   Russell Knutson
   M.Agr.Sci (hons) – Genetics/Business
   6 years International Business Management
   5 years International Marketing and Brand Management
   Project Management experience up to US $110m
   Solutions focussed
   Committed to your business outcomes
   Organised and efficient communication
   http://nz.linkedin.com/pub/russell-knutson/7/341/a4b
   russell.knutson@simcro.com




                                                           © Simcro Limited 2010
                                                                     Confidential
PAGE 2




AGENDA
>   Simcro Introduction                            01

>   Global Reach                                   02

>   Product Overview                               03

>   Recent Innovations                             04




                          © Simcro Limited 2011
                                    Confidential
PAGE 3




PARTNER.
Just as our products fit ‘hand in glove’ with the formulations they deliver, our team
of experienced and multi-talented people can be thought of as an extension to your
own team.
With internal capabilities in engineering design and development, pharmaceutical
sales, marketing, project management, and graphic design, we’ll work
collaboratively with you; to arrive at a solution specific to your product and brand
that will enhance both.
This may be as complex as analyzing chemical compatibility and matching plastics
colors to your brand palette or it may simply be guiding a new product manager
through the solution design process. No job is too big or too small.
Your account manager will then manage your project through to delivery ensuring
that you only need one point of contact.




                                                                  © Simcro Limited 2011
                                                                            Confidential
PAGE 4




INNOVATE.
Already recognised for engineering design and development excellence, 2010 was
nevertheless a champagne year for Simcro winning a number of international design
awards.
Our large team of development engineers are experts in their field and at any one
time are working on over 70 projects for our global customers. These projects are
certain to deliver an increasing number of innovative health delivery solutions such
as our award winning Sekurus and Optiline products. In fact, it’s highly likely that
some of these projects are for your own product development team.
If you have a new product coming to market and need a unique delivery system to
help it stand apart in the market, it makes sense to talk to us first.




                                                                 © Simcro Limited 2011
                                                                           Confidential
PAGE 5




DELIVER.
Delivery – on time, budget and to specification is our firm commitment to you.
Recently awarded the ISO 9001:2008 Quality Standard we’ll keep you informed of
progress throughout your project and we stand behind our products after the
project’s completion.


Please do contact Simcro for your next project. Let us demonstrate how we stand
apart from our competitors, just as you do from yours.




                                                              © Simcro Limited 2011
                                                                        Confidential
PAGE 6




ANIMAL
PASTORAL
COMPANION
AQUACULTURE
HUMAN
              © Simcro Limited 2011
                        Confidential
PAGE 7


01
SIMCRO INTRODUCTION - AWARDS

     2011                          2011                              2011
     GOLD – SEKURUS ™              SILVER – OPTILINE ™               WINNER – SEKURUS ™
     AUSTRALIAN INTERNATIONAL      INTERNATIONAL DESIGN              INTERNATIONAL FORUM PRODUCT
     DESIGN AWARD                  EXCELLENCE AWARD                  DESIGN AWARD




     2010                          2010                              2010
     WINNER – SEKURUS ™            WINNER – BEST USE R&D             WINNER – SEKURUS ™
     UNITED STATES INTERNATIONAL   NEW ZEALAND INTERNATIONAL         NEW ZEALAND AGRITECH
     GOOD DESIGN AWARD             BUSINESS AWARD                    INNOVATION AWARD




     2010                          2010                              2010
     GOLD – OPTILINE ™             WINNER – OPTILINE ™               WINNER – OPTILINE ™
     AUSTRALIAN INTERNATIONAL      POWERHOUSE MUSEUM                 INTERNATIONAL FORUM PRODUCT
     DESIGN AWARD                  SELECTION AWARD                   DESIGN AWARD




     2010                          2009                              2009
     FINALIST – OPTILINE ™         BRONZE – OPTILINE ™               WINNER – OPTILINE ™
     MELBOURNE DESIGN AWARDS       DESIGNERS INSTITUTE OF NEW        BAYER INNOVATORS AWARD FOR
                                   ZEALAND DESIGN AWARD              DESIGN AND ENGINEERING




                                                                © Simcro Limited 2011
                                                                          Confidential
PAGE 8


01
SIMCRO INTRODUCTION - BOARD & EXECUTIVES

   BOARD OF DIRECTORS




   John Dennehy          Will Rouse A.C.A.        Rod Walker BE            Jeff Excell
   Chairman              MD/ Chief Executive      Executive Director /     Director
                         Officer                  Business Development


   KEY EXECUTIVES




   Will Rouse A.C.A.     Nigel Hazelwood BMS CA   Gary Sissons             Rod Walker BE
   MD/ Chief Executive                            Dip Ag. PG DipBusAdmin   Executive Director /
                         Finance & Operations
   Officer               Manager                  Int. Sales & Marketing   Business Development
                                                  Manager




                                                                                                  © Simcro Limited 2011
                                                                                                            Confidential
PAGE 9


01
SIMCRO INTRODUCTION - QUALITY

ISO ASSURANCE



PRECISION



RELIABILITY



ACCURACY




                                © Simcro Limited 2011
                                          Confidential
PAGE 10




02
GLOBAL
REACH

         © Simcro Limited 2011
                   Confidential
PAGE 11


02
GLOBAL REACH

Simcro has a significant record of partnering
with the pharmaceutical industry globally,
undertaking many highly confidential and
market sensitive projects.
We operate in a collaborative and
professional manner with the complete
confidence of our customers.




                                                © Simcro Limited 2011
                                                          Confidential
PAGE 12


02
GLOBAL REACH - PARTNERS




                          © Simcro Limited 2011
                                    Confidential
PAGE 13


02
GLOBAL REACH - TERRITORY MANAGERS




    GARY SISSONS            RICHARD LEE     MARTY STEVENS    ANDREW SHEPHERD   RUSSELL KNUTSON
    International Sales &   UK / Europe     Asia / Pacific   US / Canada       LATAM / Africa
    Marketing Manager       Sales Manager   Sales Manager    Sales Manager     Sales Manager




                                                                                 © Simcro Limited 2011
                                                                                           Confidential
PAGE 14


02
GLOBAL REACH - DISTRIBUTORS




                              © Simcro Limited 2011
                                        Confidential
PAGE 15




03
PRODUCT
OVERVIEW

           © Simcro Limited 2011
                     Confidential
PAGE 16


03
PRODUCT OVERVIEW

As a result of our stringent quality
expectations and innovative development
approach, Simcro products enhance the
brand value of the pharmaceutical that they
deliver.
Our reputation for accuracy and user
experience spans nearly two decades and
we see ourselves as a companion to global
pharmaceutical brands.
We can also tailor our proprietary range of
products to suit our clients’ brands or
designs, adding the value of the Simcro
reputation for accuracy and delivery.




                                              © Simcro Limited 2011
                                                        Confidential
PAGE 17


03
PRODUCT OVERVIEW

INJECTORS




APPLICATORS




PACKAGING




SPECIALIST ITEMS




                   © Simcro Limited 2011
                             Confidential
PAGE 18


03
PRODUCT OVERVIEW

INJECTORS




 Simcro produces injectors for a wide range of pharmaceutical delivery options.
 Our SekurusTM range features the latest in safety innovations, minimizing the risk of self-
  injection through world-first patented technology.
 Our premium and compact ranges have a reputation for accuracy and reliability, and are
  used by many of the world’s largest pharmaceutical companies.
 All our proprietary products can be customised to suit our clients branding and colour
  requirements.




                                                                        © Simcro Limited 2011
                                                                                  Confidential
PAGE 19


03
PRODUCT OVERVIEW

APPLICATORS




 Simcro produces applicators for all types of pharmaceutical delivery.
 Our Topical and Oral applicator models include 1mL, through to 75mL.
 With a range of sizes and application styles, we can supply a proprietary range applicator
  to suit any need.
 All of our proprietary products can be customised to suit our clients branding and colour
  requirements.




                                                                       © Simcro Limited 2011
                                                                                 Confidential
PAGE 20


03
PRODUCT OVERVIEW

PACKAGING




 Simcro’s packaging products include transit and draw-off caps as well as containers and
  sleeves for both thermal insulation, physical protection and as a cradle.
 These products can be combined with our delivery devices to form a complete delivery
  solution.
 In addition, our sleeves can be customised to reflect client branding on request.




                                                                          © Simcro Limited 2011
                                                                                    Confidential
PAGE 21


03
PRODUCT OVERVIEW

SPECIALIST ITEMS




 Simcro has a number of different specialist products including implanter devices for
  animals and fish, tree injectors and thermal bottle warmers.




                                                                  © Simcro Limited 2011
                                                                            Confidential
PAGE 22




05
RECENT
INNOVATIONS

              © Simcro Limited 2011
                        Confidential
PAGE 23


05
RECENT INNOVATIONS

Our most recent developments, such as the
OptilineTM sheep drencher for Novartis
Animal Health, the SekurusTM safety injector
family for Pfizer Animal Health, and the
intramammary syringe for Merial, have all
overcome significant challenges that
previously had never been solved.
These projects highlight Simcro’s ability to
deliver solutions that others can’t imagine.




                                               © Simcro Limited 2011
                                                         Confidential
PAGE 24
                                                                    PAGE




CEFAMASTER® INTRAMAMMARY SYRINGE



SEKURUS™ WORLD’S FIRST SELF-TENTING
SAFETY INJECTOR



OPTILINE™ WORLD’S FIRST IN-LINE DRENCHER



DRAXXIN® PROTECTIVE SLEEVE



HI-VISCOSITY INJECTOR




                                           © Simcro Limited 2011
                                                     Confidential
PAGE 25


05
RECENT INNOVATIONS - CEFAMASTER              ®   INTRAMAMMARY SYRINGE


 Improved Grip
   Wider wings on the side of syringe
    designed for maximum comfort and
    efficiency.
 Contoured Cap
   Easy to grip and remove.
 Reduced Hand Fatigue
   Shorter syringe & plunger resulting in
    reduced hand fatigue.
   Better plunger base for thumb.




                                                          © Simcro Limited 2011
                                                                    Confidential
© Simcro Limited 2011
          Confidential
PAGE 27


05
RECENT INNOVATIONS - SIMCRO SEKURUS™ SELF-TENTING INJECTOR

 Protective needle guard minimises risk
  of self-injection.
 Two-stage action ensures administration
  will only occur once needle reaches
  maximum penetration depth.
 Potential for needle breakage reduced.
 Easier to administer dose in confined
  spaces.
 One-handed injection reduces stress
  and animal discomfort.
 Increased administration speed with
  needle changeover faster and safer.




                                              © Simcro Limited 2011
                                                        Confidential
© Simcro Limited 2011
          Confidential
PAGE 29


05
RECENT INNOVATIONS - OPTILINE™ INLINE DRENCHER

 Unique Nozzle Design
   Large bulbous mouth guard prevents
    over insertion of nozzle into sheep’s
    mouth.
   Improved animal welfare.
 Patented Dose Lock
   Auto-locking dose setting & bubble
    reduction.
 Innovative Method of Application
   Internal valving technology.
   Weight balance and ergonomic mode
    of action resulting in faster drench
    times.
   Designed to accommodate smaller
    hands with adjustable drench nozzle.


                                            © Simcro Limited 2011
                                                      Confidential
© Simcro Limited 2011
          Confidential
PAGE 31


05
RECENT INNOVATIONS - DRAXXIN                   ®   PROTECTIVE SLEEVE


 Durability
   Can survive a 1.2 m fall onto a
    concrete surface at - 20 oC minimising
    the risk of breakage.
 Innovative Packaging Solution
   Protects the two different Draxxin®
    bottles of the same volumetric size, yet
    quite different shapes.
   Achieved by securing the bottle with
    two sets of snap tabs, while allowing
    for easy product loading and reloading.
   Like many of our solutions, the Draxxin
    bottle sleeve is well-engineered
    simplicity.




                                                                 © Simcro Limited 2011
                                                                           Confidential
© Simcro Limited 2011
          Confidential
PAGE 33


05
RECENT INNOVATIONS - SIMCRO                     TM   HI-VISCOSITY INJECTOR


 Designed to Dispense Viscous
  Formulations
   Customised design developed using
    advanced computational fluid dynamics
    analysis and extensive field testing.
   Allows the user to maintain comfortable
    hand force while discharge time is kept
    to a practical level in temperatures
    down to -20 C.
   Dose accuracy (> 97 %).
   Hi-Flow Vented Draw-off.
   Rapid syringe refill (< 2 s v 12 s).
   Acceptable discharge effort (82 N).
   Acceptable discharge time (< 4 s v 11 s).




                                                                    © Simcro Limited 2011
                                                                              Confidential
© Simcro Limited 2011
          Confidential
THANK YOU
SIMCRO 2011

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Simcro Presentation

  • 2. PAGE 1 YOUR ACCOUNT MANAGER  Russell Knutson  M.Agr.Sci (hons) – Genetics/Business  6 years International Business Management  5 years International Marketing and Brand Management  Project Management experience up to US $110m  Solutions focussed  Committed to your business outcomes  Organised and efficient communication  http://nz.linkedin.com/pub/russell-knutson/7/341/a4b  russell.knutson@simcro.com © Simcro Limited 2010 Confidential
  • 3. PAGE 2 AGENDA > Simcro Introduction 01 > Global Reach 02 > Product Overview 03 > Recent Innovations 04 © Simcro Limited 2011 Confidential
  • 4. PAGE 3 PARTNER. Just as our products fit ‘hand in glove’ with the formulations they deliver, our team of experienced and multi-talented people can be thought of as an extension to your own team. With internal capabilities in engineering design and development, pharmaceutical sales, marketing, project management, and graphic design, we’ll work collaboratively with you; to arrive at a solution specific to your product and brand that will enhance both. This may be as complex as analyzing chemical compatibility and matching plastics colors to your brand palette or it may simply be guiding a new product manager through the solution design process. No job is too big or too small. Your account manager will then manage your project through to delivery ensuring that you only need one point of contact. © Simcro Limited 2011 Confidential
  • 5. PAGE 4 INNOVATE. Already recognised for engineering design and development excellence, 2010 was nevertheless a champagne year for Simcro winning a number of international design awards. Our large team of development engineers are experts in their field and at any one time are working on over 70 projects for our global customers. These projects are certain to deliver an increasing number of innovative health delivery solutions such as our award winning Sekurus and Optiline products. In fact, it’s highly likely that some of these projects are for your own product development team. If you have a new product coming to market and need a unique delivery system to help it stand apart in the market, it makes sense to talk to us first. © Simcro Limited 2011 Confidential
  • 6. PAGE 5 DELIVER. Delivery – on time, budget and to specification is our firm commitment to you. Recently awarded the ISO 9001:2008 Quality Standard we’ll keep you informed of progress throughout your project and we stand behind our products after the project’s completion. Please do contact Simcro for your next project. Let us demonstrate how we stand apart from our competitors, just as you do from yours. © Simcro Limited 2011 Confidential
  • 7. PAGE 6 ANIMAL PASTORAL COMPANION AQUACULTURE HUMAN © Simcro Limited 2011 Confidential
  • 8. PAGE 7 01 SIMCRO INTRODUCTION - AWARDS 2011 2011 2011 GOLD – SEKURUS ™ SILVER – OPTILINE ™ WINNER – SEKURUS ™ AUSTRALIAN INTERNATIONAL INTERNATIONAL DESIGN INTERNATIONAL FORUM PRODUCT DESIGN AWARD EXCELLENCE AWARD DESIGN AWARD 2010 2010 2010 WINNER – SEKURUS ™ WINNER – BEST USE R&D WINNER – SEKURUS ™ UNITED STATES INTERNATIONAL NEW ZEALAND INTERNATIONAL NEW ZEALAND AGRITECH GOOD DESIGN AWARD BUSINESS AWARD INNOVATION AWARD 2010 2010 2010 GOLD – OPTILINE ™ WINNER – OPTILINE ™ WINNER – OPTILINE ™ AUSTRALIAN INTERNATIONAL POWERHOUSE MUSEUM INTERNATIONAL FORUM PRODUCT DESIGN AWARD SELECTION AWARD DESIGN AWARD 2010 2009 2009 FINALIST – OPTILINE ™ BRONZE – OPTILINE ™ WINNER – OPTILINE ™ MELBOURNE DESIGN AWARDS DESIGNERS INSTITUTE OF NEW BAYER INNOVATORS AWARD FOR ZEALAND DESIGN AWARD DESIGN AND ENGINEERING © Simcro Limited 2011 Confidential
  • 9. PAGE 8 01 SIMCRO INTRODUCTION - BOARD & EXECUTIVES BOARD OF DIRECTORS John Dennehy Will Rouse A.C.A. Rod Walker BE Jeff Excell Chairman MD/ Chief Executive Executive Director / Director Officer Business Development KEY EXECUTIVES Will Rouse A.C.A. Nigel Hazelwood BMS CA Gary Sissons Rod Walker BE MD/ Chief Executive Dip Ag. PG DipBusAdmin Executive Director / Finance & Operations Officer Manager Int. Sales & Marketing Business Development Manager © Simcro Limited 2011 Confidential
  • 10. PAGE 9 01 SIMCRO INTRODUCTION - QUALITY ISO ASSURANCE PRECISION RELIABILITY ACCURACY © Simcro Limited 2011 Confidential
  • 11. PAGE 10 02 GLOBAL REACH © Simcro Limited 2011 Confidential
  • 12. PAGE 11 02 GLOBAL REACH Simcro has a significant record of partnering with the pharmaceutical industry globally, undertaking many highly confidential and market sensitive projects. We operate in a collaborative and professional manner with the complete confidence of our customers. © Simcro Limited 2011 Confidential
  • 13. PAGE 12 02 GLOBAL REACH - PARTNERS © Simcro Limited 2011 Confidential
  • 14. PAGE 13 02 GLOBAL REACH - TERRITORY MANAGERS GARY SISSONS RICHARD LEE MARTY STEVENS ANDREW SHEPHERD RUSSELL KNUTSON International Sales & UK / Europe Asia / Pacific US / Canada LATAM / Africa Marketing Manager Sales Manager Sales Manager Sales Manager Sales Manager © Simcro Limited 2011 Confidential
  • 15. PAGE 14 02 GLOBAL REACH - DISTRIBUTORS © Simcro Limited 2011 Confidential
  • 16. PAGE 15 03 PRODUCT OVERVIEW © Simcro Limited 2011 Confidential
  • 17. PAGE 16 03 PRODUCT OVERVIEW As a result of our stringent quality expectations and innovative development approach, Simcro products enhance the brand value of the pharmaceutical that they deliver. Our reputation for accuracy and user experience spans nearly two decades and we see ourselves as a companion to global pharmaceutical brands. We can also tailor our proprietary range of products to suit our clients’ brands or designs, adding the value of the Simcro reputation for accuracy and delivery. © Simcro Limited 2011 Confidential
  • 19. PAGE 18 03 PRODUCT OVERVIEW INJECTORS  Simcro produces injectors for a wide range of pharmaceutical delivery options.  Our SekurusTM range features the latest in safety innovations, minimizing the risk of self- injection through world-first patented technology.  Our premium and compact ranges have a reputation for accuracy and reliability, and are used by many of the world’s largest pharmaceutical companies.  All our proprietary products can be customised to suit our clients branding and colour requirements. © Simcro Limited 2011 Confidential
  • 20. PAGE 19 03 PRODUCT OVERVIEW APPLICATORS  Simcro produces applicators for all types of pharmaceutical delivery.  Our Topical and Oral applicator models include 1mL, through to 75mL.  With a range of sizes and application styles, we can supply a proprietary range applicator to suit any need.  All of our proprietary products can be customised to suit our clients branding and colour requirements. © Simcro Limited 2011 Confidential
  • 21. PAGE 20 03 PRODUCT OVERVIEW PACKAGING  Simcro’s packaging products include transit and draw-off caps as well as containers and sleeves for both thermal insulation, physical protection and as a cradle.  These products can be combined with our delivery devices to form a complete delivery solution.  In addition, our sleeves can be customised to reflect client branding on request. © Simcro Limited 2011 Confidential
  • 22. PAGE 21 03 PRODUCT OVERVIEW SPECIALIST ITEMS  Simcro has a number of different specialist products including implanter devices for animals and fish, tree injectors and thermal bottle warmers. © Simcro Limited 2011 Confidential
  • 23. PAGE 22 05 RECENT INNOVATIONS © Simcro Limited 2011 Confidential
  • 24. PAGE 23 05 RECENT INNOVATIONS Our most recent developments, such as the OptilineTM sheep drencher for Novartis Animal Health, the SekurusTM safety injector family for Pfizer Animal Health, and the intramammary syringe for Merial, have all overcome significant challenges that previously had never been solved. These projects highlight Simcro’s ability to deliver solutions that others can’t imagine. © Simcro Limited 2011 Confidential
  • 25. PAGE 24 PAGE CEFAMASTER® INTRAMAMMARY SYRINGE SEKURUS™ WORLD’S FIRST SELF-TENTING SAFETY INJECTOR OPTILINE™ WORLD’S FIRST IN-LINE DRENCHER DRAXXIN® PROTECTIVE SLEEVE HI-VISCOSITY INJECTOR © Simcro Limited 2011 Confidential
  • 26. PAGE 25 05 RECENT INNOVATIONS - CEFAMASTER ® INTRAMAMMARY SYRINGE  Improved Grip  Wider wings on the side of syringe designed for maximum comfort and efficiency.  Contoured Cap  Easy to grip and remove.  Reduced Hand Fatigue  Shorter syringe & plunger resulting in reduced hand fatigue.  Better plunger base for thumb. © Simcro Limited 2011 Confidential
  • 27. © Simcro Limited 2011 Confidential
  • 28. PAGE 27 05 RECENT INNOVATIONS - SIMCRO SEKURUS™ SELF-TENTING INJECTOR  Protective needle guard minimises risk of self-injection.  Two-stage action ensures administration will only occur once needle reaches maximum penetration depth.  Potential for needle breakage reduced.  Easier to administer dose in confined spaces.  One-handed injection reduces stress and animal discomfort.  Increased administration speed with needle changeover faster and safer. © Simcro Limited 2011 Confidential
  • 29. © Simcro Limited 2011 Confidential
  • 30. PAGE 29 05 RECENT INNOVATIONS - OPTILINE™ INLINE DRENCHER  Unique Nozzle Design  Large bulbous mouth guard prevents over insertion of nozzle into sheep’s mouth.  Improved animal welfare.  Patented Dose Lock  Auto-locking dose setting & bubble reduction.  Innovative Method of Application  Internal valving technology.  Weight balance and ergonomic mode of action resulting in faster drench times.  Designed to accommodate smaller hands with adjustable drench nozzle. © Simcro Limited 2011 Confidential
  • 31. © Simcro Limited 2011 Confidential
  • 32. PAGE 31 05 RECENT INNOVATIONS - DRAXXIN ® PROTECTIVE SLEEVE  Durability  Can survive a 1.2 m fall onto a concrete surface at - 20 oC minimising the risk of breakage.  Innovative Packaging Solution  Protects the two different Draxxin® bottles of the same volumetric size, yet quite different shapes.  Achieved by securing the bottle with two sets of snap tabs, while allowing for easy product loading and reloading.  Like many of our solutions, the Draxxin bottle sleeve is well-engineered simplicity. © Simcro Limited 2011 Confidential
  • 33. © Simcro Limited 2011 Confidential
  • 34. PAGE 33 05 RECENT INNOVATIONS - SIMCRO TM HI-VISCOSITY INJECTOR  Designed to Dispense Viscous Formulations  Customised design developed using advanced computational fluid dynamics analysis and extensive field testing.  Allows the user to maintain comfortable hand force while discharge time is kept to a practical level in temperatures down to -20 C.  Dose accuracy (> 97 %).  Hi-Flow Vented Draw-off.  Rapid syringe refill (< 2 s v 12 s).  Acceptable discharge effort (82 N).  Acceptable discharge time (< 4 s v 11 s). © Simcro Limited 2011 Confidential
  • 35. © Simcro Limited 2011 Confidential