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asymptomatic infection.pptx
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4. References
• 8. The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team.
The epidemiological characteristics of an outbreak of 2019 novel coronavirus
diseases (COVID-19) d China, 2020. China CDC Weekly 2020;2(8):113e22
• 9. Nishiura H, Kobayashi T, Suzuki A, Jung SM, Hayashi K, Kinoshita R, et al.
Estimation of the asymptomatic ratio of novel coronavirus infections (COVID-
19). Int J Infect Dis 2020;94: 154e5.
• 10. Mizumoto K, Kagaya K, Zarebski A, Chowell G. Estimating the asymptomatic
proportion of coronavirus disease 2019 (COVID19) cases on board the Diamond
Princess cruise ship, Yokohama, Japan, 2020. Euro Surveill 2020;25(10):2000180
5. • 11. Ki M. Epidemiologic characteristics of early cases with 2019 novel
coronavirus (2019-nCoV) disease in Korea. Epidemiol Health 2020;42:e2020007.
• 12. Kimball A, Hatfield KM, Arons M, James A, Taylor J, Spicer K, et al.
Asymptomatic and presymptomatic SARS-CoV-2 infections in residents of a
long-term care skilled nursing facility - king county, Washington, march 2020.
MMWR (Morb Mortal Wkly Rep) 2020;69(13):377e81.
• 13. Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J, et al. SARS-CoV-2 infection in
children. N Engl J Med 2020;382(17):1663e5
6. Of the 260 PCR-confirmed individuals with COVID-19, 213 (81.9%)
participated in this study. Of them, 41 (19.2%, 95% CI 14.5%e 25.1%)
had remained asymptomatic until admission.
7. • The presence of asymptomatic cases of COVID-19 was noted in early
reports on the outbreak and a large study on 72 314 Chinese patients
reported that 1% were asymptomatic
• Limitation - selection bias towards the exclusion of those with mild
symptoms
