2. INTRODUCTION
Gonioscopy
allows visualization of
the anterior chamber angle by using
direct or indirect contact lenses to overcome the
Total Internal Reflection
Enables glaucomas to be classified by assessing
whether the angle is open or closed
Various Pathologies involving angle structures can
be observed
3. HISTORICAL ASPECTS
Trantas (1907)
• 1st visualized the anterior chamber angle in a patient with
keratoglobus by indenting the limbus
• coined the term gonioscopy.
Salzmann (1914)
• Established that visualization of the angle was impossible without
optical instrumentation due to phemomenon of Total internal reflection
• Thus introduced the goniolens
Koeppe (1919)
• designed an improved steeper lens.
•
Troncoso
• developed gonioscope for magnification and illumination of
the angle.
Goldmann (1938)
• introduced the gonioprism
Barkan
• established the use of gonioscopy in the management of glaucoma
9. PRINCIPLES AND OPTICS
• Critical angle for the cornea-air interface is approximately
46 degrees.
•Total internal reflection prevents direct visualization of ang
le in nearly all eyes.
•The incident angle of light- reflected from angle is greater
than the critical angle at the cornea–air interface.
10. L i < L r
light rays are refracted at the contact l
ens-air interface
light rays are reflected by a mirror
light rays leave the lens at nearly right
angles at the contact lens-air interface
Total internal reflection is overcome by eliminate the cornea-air interface
by
Goniolenses in DIRECT method contact lenses –-to examine the
anatomy of the angle
Gonioprisms/mirror and viscous coupling solution or tears in
INDIRECT method
As the index of refraction of a contact lens approaches that of the corne
a, there is minimal refraction at the interface of these two media, which
eliminates the optical effect of the front corneal surface.
Thus light rays from the anterior chamber angle enter the contact lens a
nd are then made to pass through the new contact lens-air interface
11. METHODS
• Three primary methods:
• Indirect gonioscopy: Using mirrors,the
angle is examined with reflected light
• Indentation (dynamic) gonioscopy
• Direct gonioscopy: look directly at the
angle with lenses.
13. GONIOPRISMS
Requiring coupling agents
1.Goldmann single mirror gonioprism
Prototype diagnostic gonioprism
• Mirror inclined at 62 degrees from plano front
surface
• Needs to be rotated 3times to examine the whole
angle
• Mirror Height -12 mm
• Central well diameter -12 mm
• Posterior Radius of curvature -7.38 mm
14. 2.Goldmann two mirror gonioprism
• Both mirrors inclined at 62 degrees
• Needs to be rotated once to examine whole
angle
3.Goldmann three mirror gonioprism
15. 1.Gonioscopy mirror:
• Smallest
• Dome shaped upper border
• Inclination of 59 degrees
Broad area of contact with cornea (12 mm)
may artificially close the angle under pressure
2.Equatorial mirror:
• Largest
• Oblong shaped
• Inclined at 67 degrees
• Examine Pars plana of ciliary body
Posterior pole to the equator
3.Peripheral mirror:
• Intermediate size
• Square shaped
• Inclined at 73 degrees
• Examine from equator to ora serrata
16. 4.Allen Thorpe gonioprism
• 4 prisms instead of mirrors
• Allows examination of whole angle without rotating the
prisms
• Suspended by a frame
17. Advantages of Goldmann gonioprisms
• Easy to use
• Excellent view
• Peripheral retina can be seen
• Stabilizes the globe
Can be used in Argon Laser trabeculoplasty
18. Disadvantages of Goldmann gonioprisms
• Only 1 mirror for gonio-has to be rotated by 360
degrees
• Cannot be used for indentation
• In case of 3 mirror lens, broad area of contact with
cornea may cause artefactual closure of angle
Curvature of lens > cornea
Coupling material required
Blurs vision and fundus
Field charting ,direct and indirect ophthalmosc
opy
cant be done immediately after use
19. GONIOPRISMS
Not requiring coupling agents
1.Zeiss 4- mirror Gonioprism
• 4 identical mirrors angled at 64 degrees
• On an UNGER HOLDER
• Small area of contact with the cornea (9mm)
Indentation gonioscopy can be performed
20. Zeiss 4- mirror Gonioprism
ADVANTAGES DISADVANTAGES
• Easy to perform
• All 4 quadrants visible at sa
me time
• Rotation of 11 degrees
covers area between the
mirrors
• Indentation gonio
• Coupling material not
required,
thus fundus viewing and
photography possible
• Difficult to master
• Does not stabilise the
globe
• May open the angle
artefactually If
pressure is applied
22. 3.Sussman lens
Similar to Zeiss
but has no handle
4.Tokel Gonioprism
• Single mirror lens
• Broader viewing area
than Goldmann single mirror lens
• Convex anterior face that provides slight
magnification
• For delivery of Laser to angle
23. 5.Ritch Trabeculoplasty laser lens
• 2 mirrors tilted at 59degrees to see inferior angle
• 2 mirrors at 64 degrees to view the superior angle
• A convex button in front of a 59 degree mirror and a
64 degree mirror for extra magnification and laser
treatment
24. GONIOLENSES
Koeppe lens
• Prototype diagnostic lens
• Available in several sizes
• Most commonly used lens
for diagnostic direct gonio.
Huskins Barkan
lens
• Prototype surgical goniolens
• Used for Goniotomy
Thorpe Goniolens
Surgical and diagnostic lens for operating rooms
25. Swan jacob’s
lens
• Surgical goniolens
• used in children
Richardson Shaffer’s lens
Small lens for use in infants
Worth goniolens
It anchors to the cornea by partial vaccum
Sieback goniolens
Tiny goniolens which floats on the cornea
26. DIRECT GONIOSCOPY
• Patient in Supine position
• 4 %Xylocaine as topical anaesthesia
• Saline bridge the gap between lens and cornea
• Koeppe lens – 50 D convex lens
• External Hand held binocular microscope
• External Barker focal illuminator with other hand
• Possible simultaneous comparison of both eyes
• Image is direct and upright.
28. • Offers a panoramic, less magnified view than
indirect gonioscopy.
• Less likely to exert pressure upon the cornea or
limbus, causing errors
29. Advantages of Direct
Gonioscopy
The height of the observer may be changed to
look deeper into a narrow angle, whereas the
gonioprism is limited by the height of the mirror
Angle becomes deeper in supine position –
easier to see angle
Provides a straight-on view of the angle rather
than the mirror image given by the indirect
lenses.
Panoramic view, so 1 part of angle can be com
pared to other
30. Goniolens may cause less distortion of the ante
rior chamber
Using 2 lenses,both eyes can be
simultaneously examined
Possible to vary the angle of visualization
more easily. Therefore, a narrow angle can be
assessed to see if it is a steep approach to an
open angle or a completely closed angle.
Can be used for surgical procedures like gonioto
my and goniosynechialysis
Can be used in sedated or anesthetized patient
s, as in the examination of children
31. Disdvantages of Direct
Gonioscopy
Inconvenient
Annoying light reflexes from the cornea
Timeconsuming
Benefits of slit lamp not available
32. INDIRECT GONIOSCOPY
PROCEDURE
Dim illumination
Eye anaesthetised with topical agent
Appropriate positioning of the patient at slit lamp
33. The concave face of Goldmann lens should be filled with a Methyl
cellulose coupling fluid before its applied to the eye.
Care should be taken to keep air bubbles out of the solution
34. Patient is asked to look down
Thumb used to retract the upper eyelid
Lower edge of gonioscope placed on inferior sclera
Gonioscope tipped on to the cornea in 1 smooth
maneouvre
35.
36. Slit lamp gonioscopy
• The part that is viewed is 180 degrees away from
the mirror that is being used.
• Slit lamp beam is focussed on the mirror that
shows the angle diametrically opposite to it.
• Image is inverted but not laterally reversed
• Illumination and height of slitlamp
are reduced so that it doesn’t
impinge on the pupil and cause
pupillary constriction and
Artefactual opening of angle.
37. • With a narrow, short slit beam off axis, the quadrant o
f the angle to be assessed is first examined with the f
our-mirror lens, with
no pressure on the cornea
the patient looking sufficiently far in the direction of the
mirror that the examiner can see as deeply into the angl
e as possible.
• The inferior portion of the angle is typically the
widest and where the trabecular meshwork has the
most pigment, thus easiest to identify
structures and familiarize with patient ‘s anatomy
• Thus most clinicians apply lens so that mirror is at the
top of the eye, to allow inferior angle to be examined
first.
• Then the goniolens is rotated to view other portions
of the angle
40. • Using a narrow slit beam at an oblique angle
• 2 linear reflections identified from
external surface of cornea and its junction with sclera
Internal surface of cornea
• They meet at Schwalbe s line.
• Slit of light appears above Schwalbe ‘s line as a 3D parallelepiped
of light.
• Used for identifying landmarks in patients with
Closed angles
Open angles with no trabecular meshwork pigmentation
41.
42. Advantages of Indirect
Gonioscopy
• Easier to learn
• Faster to perform, particularly with the Zeiss
four-mirror lenses and modified Goldmann-type
lenses, because no viscous bridge is required.
• Slitlamp provides better optics, variable
magnification and illumination
• Requires fewer additional instruments and
occupies less space than direct gonioscopy.
• Gonioprisms with a posterior radius of curvature closer
to that of the anterior corneal surface may also reduce
Corneal distortion.
43. • Gonioprisms with taller mirrors facilitate
visualization of narrow angles.
• The slit beam can create a corneal wedge to help to
define the structures of the angle.
• Because of its relatively small diameter of
corneal contact, the Zeiss four-mirror lens
can also be used in compressive gonioscopy.
• Indentation gonioscopy can be performed with the
Posner or Sussmann lens to distinguish
appositional from synechial angle closure.
• Magnified stereoscopic view of the optic disc can be
obtained
44. Disadvantages of Indirect
Gonioscopy
• Limited positioning of light rays
• Comparison not possible
• Difficult to perform in horizontal meridian
• Inverted Mirror image seen – confusing
• Excess pressure over the cornea will displace aqueous from
the center of the anterior chamber into the periphery,disloc
ating the iris posteriorly and falsely opening the anterior ch
amber angle.
• Posterior pressure may indent the sclera and falsely narrow
the angle.
45. • Goldmann lens requires an optical coupling
between the cornea and the lens.
( four-mirror Zeiss lens ,Posner, Sussman have a
smaller area of contact and have almost the same
radius of curvature as the cornea, which allows the
tear film to function as the optical coupling agent.)
46. Occludable Angles
During Gonioscopy in situ
(No angle structures are visible)
Optical or Apparent
closure
Appositional closure
Synechial Closure
Look for abnormalities in angle
Manipulative gonioscopy
Indentation gonioscopy
47. To look for angle abnormalities
• Increase the room and slit lamp illumination
• Allow light to impinge on pupil
• Thereby opening up angle
48. Manipulative/Dynamic Gonioscopy
In eyes with a steep iris configuration
manipulate Goldmann lens to visualise over
a steep iris
(OVER HILL VIEW)
Ask patient to look in direction of mirror or
Move mirror towards angle being viewed
49. Indentation Gonioscopy
performed in a completely darkened room usi
ng the smallest square of light for a slit beam
to avoid stimulating the pupillary light reflex.
Effective with Zeiss , Posner, Sussman ,Allen
Thorpe lens whose areas of contact are small
er than the cornea(no coupling media)
Goldmann and Koeppe have larger areas of c
ontact and may make the angle shallower wit
h indentation
50.
51. • Bending of the cornea results in mechanical rotation of the li
mbus, giving more direct view of the angle
• Permits examiner to look deep into angle recess for
iridodialysis, foreign bodies or cyclodialysis clefts
• By deliberately varying the amount of pressure
applied to the cornea- observe the effects on
angle width.
• Measures extent of angle closure
• Useful in convex iris configuration and Plateau configur
ation - (retain convex profile)
• Performed in all cases
• The ability to visualize angle structures by indentation-redu
ced in the presence of elevated intraocular pressure.
54. Corneal edema
In patients with corneal edema ,
topical anaesthesia followed by Glycerin
Short lived effect
In goniotomy, visualisation of edematous corneal epithelium after
it is scraped away after wetting the cornea with 70 % ethyl
alcohol
55. INDICATIONS
• Shallow Ant chamber
• High IOP
• Pigment dispersion
• Pseudoexfoliation
• History of Blunt trauma
• NVI
• Ocular Inflammation
• Compromised Vascular system of Reti
na
58. Interpretation of
gonioscopy findings
PUPIL
• looking at the pupil for rapid orientation.
• Anterior lens surface can be observed for focal
opacifications (glaukomflecken) and for poster
ior synechiae.
• View the white dandruff-like flecks of exfoliative
pigment at the posterior edge of the pupil, whi
ch is typical of exfoliative syndrome.
• Iridodonesis is present to a small degree in so
me deep-chambered Normal eyes and is easily
observed if of a pathologic degree.
59. IRIS
• Configuration of the peripheral iris
contour of the iris, noting its flatness -deep anterior
chamber
convexity (or even bowing) -a shallow anterior cham
ber
peripheral concavity -high myopia or
signs of pigment dispersion
• Site of iris insertion
in reference to structures within the angle recess
at the level of the upper trabecular meshwork and S
chwalbe’s line
at the level of the filtering trabecular
meshwork
just below the scleral spur
below the spur in the ciliary body
deep posteriorly in the ciliary band.
60. Anteriorly inserting irides, at the level of the spur or
TM -more common among Asians and in patients
with hyperopia.
• Angulation between the iris insertion and the slo
pe of the inner cornea in the angle, in approxima
te steps of 10°.
This systematic assessment of angle anatomy is
the basis of the most detailed gonioscopic gradin
systems.
• Abnormalities such as neovascularization, hypop
lasia,atrophy, and polycoria should be noted.
61.
62. CILIARY BODY BAND
• The ciliary body band appears as a densely pigmented
band just behind Scleral Spur
• dull-brown to slate grey band
• Width depends on position of iris insertion
(Narrower -- hyperopes
wider – myopes )
• If abnormally deep and not symmetrical with the other
eye –
angle recession
Cyclodialysis
unilateral high myopia
63. SCLERAL SPUR
• Site of attachment of longitudinal muscle of Ciliary Body
• Appears as narrow, dense, shiny white band
• Imp. Landmark (relatively consistent appearance)
• Blood in the Schlemm ‘s canal –lies anterior to spur
64. SCHLEMM’S CANAL
• Lies deep to posterior trabeculum
• Normally not visible
• Seen if blood is present in Increased Episcleral V
enous Pressure
– Gonio lens - pressure
– Carotid-cavernous fistula
– Sturge Weber syndrome
– Venous Compression
– Hypotony
65. TRABECULAR MESHWORK
• Pigmented band anterior to Scleral Spur
• Width - 600µm
• Gonioscopic appearance - Ground glass, irregularly roughened due
to large openings of uveal meshwork
• 2 parts
Anterior - non functional part (White)
Posterior - functional pigmented part (greyish blue)
primary site of aqueous outflow
• has no pigment at birth, but with age, color develops, from f
aint tan to dark brown, depending on the degree of pigment
dispersion in the anterior chamber.
• distribution of pigment may be homogeneous in some and ir
regular in others.
66. SCHWALBE’S LINE
• Collagen condensation of descement membrane between T.M. and
endothelium
• Thin translucent line or ridge like structure
• The corneal wedge-identifying the schwalbe’s line
• Using a narrow slit beam at an oblique angle
• 2 linear reflections identified from
external surface of cornea and its junction with sclera
Internal surface of cornea
Parallelopiped beam of light is seen , apex of which corresponds to
Schwalbe s line.
67. IRIS PROCESSES
• Small extensions from anterior surface of iris to level of Scleral
Spur but sometimes as far anteriorly as schwalbe’s line
• Lacy fenestrated
• Underlying angle structures visible between strands
• Seen in 1/3 rd of normal eyes –not pathological
• Prominent in myopes / brown eyes
• Common in nasal Quadrant
68. Iris Processes
Lacy fenestrated
Underlying angle stru
ctures visible between
strands
Tend to follow
recess
PAS
Iridocorneal adhesions
Short ,stout projections
May obscure the scleral spur
Bridge the recess
Tether iris to angle and
interfere with posterior
motion of the iris during
Indentation
69. Blood Vessels in the Angle
• Two types
Circumferential vessels
• found at the base of the iris or in the angle recess.
• Appearance- of an undulating “sea serpent”
• with segments of blood vessel visible against the ciliary body, punctuate
d by areas where the vessel dips posteriorly and out of view
• never seen attached to the angle anterior to the scleral spur.
Radial iris vessels within the iris stroma - mimic corkscrews
Normal angle vessel
• Broad
• Appears in short segment
• Not extend anterior to S.S
pur
• Do not arborize in the T.
M
Pathological angle
vessels
• Fine
• Cross the scleral spur
• Branch, arborize in T.M.
70. Sampaolesi line
• Line of irregular pigmentation deposit anterior to
Schwalbe’s line
• sampaolesi’s line can be mistaken for trabecular m
eshwork in narrow angle
Sampaolesi’s Line
Salt , pepper
Dark granular
Discontinuous
Pigmentation T.M
Brown sugar
Fine
Continuous
71. ARTIFACT AND AVOIDANCE
• Use thin slit lamp
• illumination
• Goldman type lens - avoid indentation- cause ar
tificially narrowing of angle
• Zeiss - avoid pressure artificial widening of the
angle
72. INTERPRETATION OF
GONIOSCOPIC FINDINGS
• Several grading systems- describe the
width of the anterior chamber angle a
nd its potential for angle closure.
• Shaffer, Scheie, and Spaeth-three most
commonly used systems.
76. • Spaeth also graded posterior pigmented
meshwork in the 12 o’clock angle on a scale
Of 0 to 4+ and this grade is often assigned
separately at the end of the gonioscopic
description.
78. CLINICAL USES
• Aid in diagnosis of type of glaucoma
Open Vs closed angle
Narrow angle
Cause of sec. Glaucoma
• Decision of iridotomy
• Pre-Operative examination
• Post operative evaluation
Ostium
Cleft goniotomy / cyclodialysis
Iridotomy
• Assess K-F ring (Wilson)
• Therapeutic
Goniotomy
Laser procedure (ALT)
Chamber deepening procedure
Acute angle closure –break synechia by indentati
on
79. • NEOVASCULARIZATION OF ANGLE:
• Vessels- erratic course and/or extend anteriorly past the level of
the scleral spur.
• Vascular retinal abnormalities such as
diabetic retinopathy
retinal venous or arterial occlusions
ocular ischemic syndrome.
• accompanied by PAS
• Heterochromic cyclitis-
vessels are fewer, finer
not accompanied by
peripheral anterior synechiae.
• Healed cataract incision
PATHOLOGICAL FINDINGS
80. PLATEAU IRIS
Unusual form of primary
angle closure , not by
pupillary block.
Angle closed by prominent
last roll of iris and
abnormal approach of iris
to angle
A patent PI or iridotomy
must be present for the
diagnosis
Ciliary processes –
abnormally forward
On indentation , central iris
is pushed back but
peripheral iris held up by
ciliary processes
95. Disinfection
• With all lenses the manufacturer's instructions for disinfection should
be followed to prevent damage to the lens.
• It is important to carefully remove the disinfectant from the contact s
urface before the next use, because alcohol and hydrogen peroxide e
ach cause transient corneal defects.
• Most lenses can be gas-sterilized and some glass lenses can be autoc
laved.
• Most common method is inverting the contact lens and wiping the s
urface with an alcohol sponge.
• lens can be inverted and the concave contact area filled with a
solution of 1: 10 household bleach, which is left for 5 min and then
rinsed off with water.
Adenovirus
type 8
soaking the lens for 5 to 15 minutes in diluted sodium hypochlo
rite (1:10 household bleach), 3% hydrogen peroxide, or 70% is
opropyl alcohol, or by wiping with alcohol, hydrogen peroxide, i
odophor (povidone-iodine), or 1:1000 Merthiolate
HSV Type1 swabbing the lens with 70% isopropyl alcohol
HBV Ten minutes of continuous rinsing in running tap water
HIV-1 Wipe with 3% hydrogen peroxide or 70% isopropyl alcohol swab
s
96. REFERENCES
1.SHIELD ‘S TEXTBOOK OF GLAUCOMA 6th e , by R RAND AL
LINGHAM
2. BECKER –SHAFFER S DIAGNOSIS AND THERAPY OF GLAU
COMAS
3.THE GLAUCOMA BOOK , A PRACTICAL EVIDENCE BASED A
PPROACH TO PATIENT CARE by Paul N. Schacknow
4. HANDBOOK OF GLAUCOMA by Augusto Azuara- Blanco
5.THEORY AND PRACTICE OF OPTICS AND REFRACTION by
A.K. Khurana
6.COLOUR ATLAS OF GONIOSCOPY by Wallace L.M. Alward
Hinweis der Redaktion
limbus is the transition zone between the cornea and the sclera.
On the inner surface of the limbus is an indentation; the scleral sulcus, which has a sharp posterior margin- the scleral spur; and a sloping anterior wall that extends to the peripheral cornea
A sieve-like structure, the trabecular meshwork, bridges the scleral sulcus and converts it into a tube, called the Schlemm canal.
Where the meshwork inserts into the peripheral cornea, a ridge is created, known as the Schwalbe line.
The Schlemm canal is connected by intrascleral channels to the episcleral veins.
The trabecular meshwork, Schlemm canal, and the intrascleral channels make up the main route of aqueous humor outflow
ciliary body attaches to the scleral spur and creates a potential space, the supraciliary space, between itself and the sclera.
On cross section, the ciliary body has the shape of a right triangle, and the ciliary processes (the actual site of aqueous humor production) occupy the innermost and anterior-most portion of this structure in the region called the pars plicata (or corona ciliaris).
The posterior portion of the ciliary body, called the pars plana (or orbicularis ciliaris), has a flatter inner surface and joins the choroid at the ora serrata.
The pars plicata region is also composed of smooth muscle, which serves the important functions of accommodation and uveoscleral outflow.
The iris inserts into the anterior side of the ciliary body, leaving a variable width of the latter structure visible between the root of the iris and the scleral spur, referred to as the ciliary body band.
The lens is suspended from the ciliary body by zonules and separates the vitreous posteriorly from the aqueous humor anteriorly.
The iris separates the aqueous humor compartment into a posterior and an anterior chamber, and the angle formed by the iris and the cornea is called the anterior chamber angle
FROM ANTERIOR TO POSTERIOR
When light passes from a denser medium with a greater index of refraction to one with a lesser index
Light is transmitted when i< r
i= critical angle when r is 90 degrees.
When i exceeds the critical angle, r >i , the light is reflected back into the first medium.
In direct gonioscopy, the anterior curve of the contact lens—the goniolens—is such that the critical angle is not reached, and the light rays are refracted at the contact lens-air interface
In indirect gonioscopy, the --leave the lens at nearly a right angle to the contact lens-air interface
Indentation pressure over the cornea will displace aqueous from the center of the anterior chamber into the periphery towards the
angles ,pushes the iris posteriorly and
falsely opening the anterior chamber angle
Angle opens up on Indentation but TM is seen as patchy areas of pigmentation between which we can see patchy areas of PAS
Iris is gradually encroaching on to tm
Based on the angle between iris and Trabecular meshwork
estimated angle between a line tangential to the trabecular meshwork and a line tangential to the surface of the iris about one-third of the way from the periphery
“f” to denote a flat configuration
“c”to describe the “concave” iris,
“b” to describe the forwardly “bowed” iris
“p” for a plateau iris configuration.
Pigment dispersion throughout the anterior segment
Tears in the iris as a result of blunt trauma
As a result of very severe blunt trauma – tear in the face of ciliary body , between longitudinal and circular muscles.
Increased risk of glaucoma
Wide ciliary band and deep AC
Iris bombe occurs in patients with secluded pupil as aqueous humour trapped in posterior chamber pushes iris forward