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Reports Corner
Global Pharmaceutical & Biotechnology Outlook
2013: Japan Pharma
DescriptionDescription
Reports Cornerwww.reportscorner.com
The coming years will see Japan pharma regaining its status as
innovator driven with Edoxaban for Daiichi Sankyo, Canagliflozin
for Mitsubishi Tanabe, and Dolutegravir for Shionogi bringing the
good times back for the respective companies in 2013 and
carrying enough potential to change global market dynamics in
the anticoagulant, diabetes and HIV space resp. We think that the
massive ~$45b poured in acquiring innovation by Japanese
companies does not justify its value as we find that the key
catalysts from Japan are in-house candidates.
Brief SummaryBrief Summary
Reports Cornerwww.reportscorner.com
The coming years will see Japan pharma regaining its status as
innovator driven with Edoxaban for Daiichi Sankyo, Canagliflozin
for Mitsubishi Tanabe, and Dolutegravir for Shionogi bringing the
good times back for the respective companies in 2013 and
carrying enough potential to change global market dynamics in
the anticoagulant, diabetes and HIV space resp. We think that the
massive ~$45b poured in acquiring innovation by Japanese
companies does not justify its value as we find that the key
catalysts from Japan are in-house candidates. Changing political
scenario in Japan will accelerate the pace of reforms in Japan as
recently; the Liberal Democratic Party (LDP) of Japan came back
into power replacing the short tenure of the Democratic Party of
Japan (DPJ). LDP was the pioneer initiator of major healthcare
reforms with a focus on curbing healthcare costs by means of
enhancing generic drugs penetration. Our report discusses in
details about the implications of these changes on Innovator and
generic domestic Japanese pharma companies.
Brief SummaryBrief Summary
Reports Cornerwww.reportscorner.com
Global companies on the other hand are going to see a favorable
scenario in coming years - expected launches in 2013-2014 from
global companies will increase competition to domestic players
mainly in the respiratory, oncology and rheumatoid arthritis
therapy areas, and will increase overall market size of Diabetes
and Osteoporosis markets.
Going forward, for 2013 –Generic companies will continue to
witness a growth story, we think that the recent incentives to
promote generic uptake have played out well and at current levels,
we do not see meaningful growth until early 2014 when new set of
incentives will start playing off. However, in the related space –
drug chain stores and biogenerics are two new arenas which we
see as next growth drivers – we have analyzed these two novel
spaces as well in this report.
Brief SummaryBrief Summary
Reports Cornerwww.reportscorner.com
The detailed 146 pages report on Japan Pharma contains:
I. Performance in 2012 – The Hits & Misses
II. Japan Pharma: Looking forward in 2013 and beyond
Stand on individual companies
Changing political scenario is likely to accelerate the pace of
reforms
III. Analysis on Innovators Companies – Innovation and
consolidation continue to serve as catalyst
Rich looking pipeline could be delusive
Key R&D catalysts from Japan pharma
Key upcoming milestones
Expected upcoming launches from global companies in Japan
and its implications
Likely implications of recent consolidation activities
Sustainability thru increasing overseas base
IV. Analysis on Generic Companies
Brief SummaryBrief Summary
Reports Cornerwww.reportscorner.com
2012 – price cuts & implications
New layer of reforms playing out well
Dominance of big players in dispensing pharmacy
Shrinking general practitioners market
DPC hospitals are a new growth avenue
V. Analysis on Drug Chain Stores
Macro forces favoring Drug Chain Stores
Success story from a few, likely to be replicated by followers
VI. Analysis on Biogeneric Companies
Evolving Biogenerics space in Japan
IN-DEPTH COMPANY ANALYSIS AND REPORTS ON
Daiichi Sankyo- Edoxaban will bequeath wings to the price
Kyorin – Respiratory Franchise Strengthening Up
Mitsubishi Tanabe- Canagliflozin is key, but other drivers also in
queue
Shionogi- Dolutegravir brings the good times back
Brief SummaryBrief Summary
Reports Cornerwww.reportscorner.com
Eisai- 'HAYABUSA' challenging to achieve despite new approvals
Astellas- Defensive Agreements dilute Catalysts Value
Chugai – Growth story well built in price
Dainippon Sumitomo- Expectation from Latuda are well built in
Kyowa Hakko Kirin- Upside from Potelligent technology is still
away
Nippon Chemiphar - Thin margins, wavering profitability outlook
Sawai- Wait until next price cuts
Takeda- EU Aspirations are hard to attain
Towa- Solid fundamentals not sizeable in near term
KEY INDUSTRY TABLES/ ANNEXURES:
Japan Pharma Valuation
Key Pipeline Candidates- Japan Pharma
Global Companies expected major launches in Japan- 2013/14
Consolidation activities major M & A in Japan- Last 5 Years
Reforms in 2012 and Implications
Brief SummaryBrief Summary
Reports Cornerwww.reportscorner.com
Revised Incentives for Pharmacies
Looming Generic Opportunity
Japan Generic segments
Drug Chain stores- Profitability Trends
Key Milestones
Japan Generic Market Model
Top 25 Products vs. Generic Threat
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
I. Performance in 2012 – The Hits & Misses
II. Japan Pharma: Looking forward in 2013 and beyond
-- Stand on individual companies
-- Changing political scenari-- is likely t-- accelerate the pace of reforms
III. Analysis on Innovators Companies – Innovation and consolidation
continue t-- serve as catalyst
-- Rich Looking Pipeline Could be delusive
-- Key R&D catalysts from Japan pharma
-- Key upcoming milestones
-- Expected upcoming launches from global companies in Japan and its
implications
-- Likely implications of recent consolidation activities
-- Sustainability thru increasing overseas base
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
IV. Analysis on Generic Companies
-- 2012 – price cuts & implications
-- New layer of reforms playing out well
-- Dominance of big players in dispensing pharmacy
-- Shrinking general practitioners market
-- DPC hospitals are new growth avenue
V. Analysis on Drug Chain Stores
-- Macr-- forces favoring Drug Chain Stores
-- Success story from a few, likely t-- be replicated by followers
VI. Analysis on Biogeneric Companies
-- Evolving Biogenerics space in Japan
Japan Pharma - Company Analysis
1. DAIICHI SANKY-- (4569): Edoxaban Will Bequeath Wings T-- The
Price!
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
• Sum of parts valuation
• Lixiana/Edoxaban-Has Key Differentiating Features
• Key clinical data analysis
• Denosumab: Will Contribute T-- Bottom Lines Despite Partnering
• Worst Is Priced In For Ranbaxy Performance
• Daiichi Sanky-- Espha (DSE) - A Game Changer In Japan Generic Market
2. KYORIN (4569): Respiratory Franchise Strengthening Up!
• Catalyst t-- strengthen respiratory frenchise
• KRP-108 – The key driver
• Kipres Continues T-- Drive Growth In Anti-Asthmatic Market
• Uritos Sales Ramping Up Well
• Rapport with GPs Keeps Mucodyne Sales Stable:
• Key In-House Candidates Look For Partners
3. MITSUBISHI TANABE (4508): Canagliflozin is Key, But Other Drivers
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
Als-- In Queue!
• Canagliflozin Is Showing Promise Of Better Safety And Efficacy
• Canagliflozin : CV Safety Issues Are Manageable
• Domestic Business Faces High Long-Listed Exposure, New Catalysts Will
Continue T-- Grow
• Remicade Franchise And Telavic Will Support Declining Domestic
Business
• Teneligliptin Set T-- Enjoy Favorable DPPIV Market In Japan
• Royalty Income From Gilenya Continues T-- Grow
• Avanafil Prospects Depends Upon Vivus Marketing Partner
• Higher Dividend Expected During MTP
4. SHIONOGI (4507): Dolutegravir Brings The Good Times Back!
• Dolutegravir/comb-- approval likely in 2013
• Dolutegravir - Combination Therapy Offers Wider Opportunity
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
• Rapidly Changing HIV Market Dynamics
• Strategic Rational of Integrase Inhibitors
• Crestor – NRx/TRx Show Better Resilience Post Lipitor Generics
• 'Low Margin Domestic Business' is Not Going t-- Change Soon
• Pipeline Has Potential but Unlikely t-- Give Breakthroughs in Near Term
• US Business – Nothing Left For Further Downside
5. EISAI (4523): 'HAYABUSA' Challenging t-- Achieve Despite New
Approvals!
• Pipeline Potential Overly Built in Price
• Challenges at domestic front will Surface Soon
• Biomarker's Upside Is 'beyond HAYABUSA timeline'
• Aricept Lifecycle Management Programs Unlikely t-- Meet Management's
Target
• Halaven clinical data is encouraging for triple negative breast cancer
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
• Fycompa prospects in US are limited due t-- genericization of the market
• Belviq label will restrict its peak sales and agreement with Arena leaves
little on bottom line
6. ASTELLAS (4503): Defensive Agreements Dilute Catalysts' Value!
• Enzalutamide: 2013/14 Will Unfold Potential
• Myrbetriq Launch Will Help Maintaining Leadership In The OAB Space
• Tivozanib US Approval In RCC Is Likely But Has Limited Potential
• ASP-015k Finds A Strong Partner
• ASP-015k Deal Summary
7. CHUGAI (4519): Growth Story Well Built In Price!
• Actemra T-- Gradually Increase Its Patient Base
• Pertuzumab Will Secure Approval In Japan
• T-DMI Us Approval In Second Line Breast Cancer Is Likely
• Safe Domestic Business And Sales Ramp Up Of Newly Launched Products
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
• Roche's Possible Course Of Actions For Increasing Stake In Chugai
8. DAINIPPON SUMITOM-- (4506): Expectations From Latuda Are Well
Built In!
• LATUDA continue t-- succeed
• High Unmet Need Still Exists In The Anti-Psychotics Market
• Other Pipeline Candidates
9. KYOWA HAKK-- KIRIN (4151): Upside From Potelligent Technology Is
Still Away!
• Potelligent technology still a away from fetching premium
• Business Restructuring Brings Focus on Pharma Business
• Tivantinib Looses Its Commercial Attractiveness
• KW-0761 – First Potelligent Based Antibody in Market
10. NIPPON CHEMIPHAR (4539): Thin Margins, Wavering Profitability
Outlook!
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
• Lowest Profitability Structure Is Not Going T-- Change Soon
• Increasing DPC hospitals are biggest driver
11. SAWAI (4555): Wait Until Next Price Cuts!
• Excellent Reach in DP Segment is Advantageous
• DPC Opportunity is Yet t-- be Tapped
• Bio-Similars Opportunity Placed Aside for Now
• Premium valuation vs. Peers is Likely t-- be Maintained
• Emerging Threats T-- Domestic Generic Companies
12. TAKEDA (4502): EU Aspirations Are Hard t-- Attain!
• Increasing competition in DPPIV inhibitors class
• Global approval of SYR-322 and its combination is still awaited
• EDARBI – 'Me Too' ARB Will Alleviate Pain of Atacand Revenue Loss
• Tofacitinib JP Approval will strengthen its RA portfolio
• Nycomed acquisition helps deliver the growth and negate Actos patent expiry
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
• Key Global late stage Pipeline Candidates
• Vortioxetine US approval is likely
• Key candidates from Millennium
• TAK-875 Data in 'The Lancet' - First GPR-40 agonist Can Potentially
Alter Diabetes Therapy Paradigm, Though a Few Questions Remain
Unanswered
13. TOWA (4553): Solid Fundamentals Not Sizeable In Near Term!
• Modest Sales sustainability from Dispensing Pharma
• Ambitious Investment Plans T-- Meet Future Demand
• Emerging Threats T-- Domestic Generic Companies
List of Charts
1. Generic Penetration Trend
2. Key Generic Companies: Sales Break Up
3. Anticoagulants Market-2009 Vs. 2020
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
4. Spring- PhIII Findings (1)
5. Spring- PhIII Findings (2)
6. Dolutegravir PhIII Program
7. E-5501 - Short And Long Term Platelet Responses
8. Asp015k – Changes From Baseline In PASI At Day 42
9. Latuda: Monthly TRx Trend – Us
10. Atypical Anti-Psychotics Market
11. Atypical Anti-Psychotics – Competitive Landscape
12. Japan: Long Listed Drugs And Generic Penetration (2012)
13. Tak-875 PhII Efficacy Data
14. Type 2 Diabetes Market
List of Tables
1. Report Card – 2012 (Japan Pharma Stock Performance Hit & Miss)
2. Japan Pharma Valuation
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
4. Key Pipeline Candidates- Japan Pharma
5. Global Companies Expected Major Launches In Japan- 2013/14
6. Consolidation Activities Major M&A In Japan - Last 5 Years
7. Japanese Global Cos Overseas Sales
8. JP Companies Performance Vs. US/EU
9. Reforms In 2012 And Implications
10. Revised Incentives For Pharmacies
11. Looming Generic Opportunity
12. Key Generic Companies: Sales Break Up
13. Generic Companies: Relative Standing
14. Japan Generic: Segments
15. Drug Chain Stores: Profitability Trend
16. Biogenerics Opportunities In Japan
17. Daiichi Sankyo: Datablock
18. Daiichi Sankyo: Sum Of Parts
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
19. Daiichi Sankyo: Key Milestones
20. Daiichi Sankyo: Relative Clinical Profile Of Xarelto, Eliquis And Edoxaban
In SPAF
21. Daiichi Sankyo: Different Geographies
22. Daiichi Sankyo: Edoxaban PhII Clinical Study In SPAF: Global; Japan;
Taiwan
23. Daiichi Sankyo: Baseline Characteristics Comparison Of Pivotal Trials In
SPAF
24. Daiichi Sankyo: Comparison Of Available Osteoporosis Treatments
25. Daiichi Sankyo: Ranmark (Denosumab) - Development Status In Japan
26. Daiichi Sankyo: Comparison Between Zometa And Denosumab In
Oncology
27. Daiichi Sankyo: RBXY: Datablock
28. Daiichi Sankyo: Daiichi Sanky-- Espha Approvals
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
29. Kyorin - Datablock
30. Kyorin -Key Milestones
31. Kyorin -KRP-108: Relating Composition
32. Kyorin -Kipres: Competitive Landscape In Japan
33. Kyorin - Japanese OBS Market
34. Mitsubishi Tanabe - Datablock
35. Mitsubishi Tanabe - Key Milestones
36. Mitsubishi Tanabe – SGLT2 Pipeline (Japan And Global Status)
37. Mitsubishi Tanabe – SGLT2 Inhibitors- Clinical Data Comparison
38. Mitsubishi Tanabe - Key Products
39. Mitsubishi Tanabe - Japan RA Market
40. Mitsubishi Tanabe - HCV Pipeline (Japan)
41. Mitsubishi Tanabe - Marketed DPP4 In Japan
42. Mitsubishi Tanabe - DPP4 Pipeline* (Japan And Global Status)
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
42. Mitsubishi Tanabe - DPP4 Pipeline* (Japan And Global Status)
43. Mitsubishi Tanabe - Avanafil : Relative Positioning
44. Mitsubishi Tanabe - Dividend Estimates
45. Mitsubishi Tanabe - Key Pipeline Candidates
46. Shionogi - Datablock
47. Shionogi - Key Milestones
48. Shionogi - Single Trial Data
49. Shionogi - Dolutegravir – PhIII Trials
50. Shionogi - HIV Marketed Drugs
51. Shionogi - HIV Pipeline Drugs
52. Shionogi - Spring-2 Trial Data
53. Shionogi - Dolutegravir NPV- Shionogi
54. Eisai - Datablock
55. Eisai - Key Milestones
56. Eisai - Key Pipeline Candidates
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
57. Eisai - Aricept WW Sales Projections
58. Eisai - Aricept Sales In Japan: Strength Wise
59. Eisai - Halaven – A Number Of Indications Underway
60. Eisai - Upcoming Competitors For Halaven
61. Eisai - Fycompa Clinical Data
62. Eisai - Data Presented At IEC Annual Meeting 2011
63. Eisai - Eritoran Vs. Xigris: Comparative Efficacy
64. Astellas - Datablock
65. Astellas - Key Milestones
66. Astellas - Long-Term PhI/II Follow-Up Results
67. Astellas - Overactive Bladder Syndrome: Key Drugs
68. Astellas - Mirabegron Efficacy And Tolerability Results In European And Australian Patients
69. Astellas - Mirabegron Efficacy And Tolerability Results In North American
Patients
70. Astellas - Competitive Landscape: Advanced Renal Cell Carcinoma
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
71. Astellas - Select Oral Ra/Psoriasis Drugs In Development
72. Chugai - Datablock
73. Chugai - Key Milestones
74. Chugai - Actemra - Ongoing Global Trials
75. Chugai - Japan RA Market
76. Chugai - Efficacy And Safety Comparison Of TDM1 Vs.
Trastuzumab+Docetaxel In First Line BC TDM1: Ongoing Important
Clinical Studies Of T-DM1 In Late Stage Her 2 Positive Breast Cancer
77. Chugai - Chugai-Sales Break Up
78. Dainippon Sumitom-- - Datablock
79. Dainippon Sumitom-- - Key Milestones
80. Dainippon Sumitom-- - Psychiatrists See High Unmet Need
81. Dainippon Sumitom-- - Lurasidone - Ongoing/Planned Clinical Studies
82. Dainippon Sumitom-- - Pearl 2 Data
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
83. Dainippon Sumitom-- - Pearl 3 Vs. Seroquel: Overall- A Good Risk/Benefit
Ratio
84. Dainippon Sumitom-- - Latuda SWOT Analysis
85. Dainippon Sumitom-- - Pearl 3 Extension Study Data- Non Inferior To
Seroquel XR
86. Dainippon Sumitom-- - Dainippon Sumitomo-Key Pipeline Candidates
87. KHK - Datablock
88. KHK - Key Milestones
89. KHK -Potelligent Technology
90. KHK -Segment Classification
91. KHK -Income Statement
92. KHK -Pharma Sales Trend
93. Nippon Chemiphar - Datablock
94. Nippon Chemiphar - Entry Of Foreign Companies In Japan Generic Market
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
95. Nippon Chemiphar - Generic Companies: Relative Valuation
96. Sawai - Datablock
97. Sawai - Excellent Reach In Various Markets
98. Sawai - Reforms In 2012 And Implications
99. Sawai - Sawai Vs. Key Competitors Sales Break Up Key
100. Sawai - Generic Companies: Relative Valuation
101. Sawai - Foreign Companies Entry In Japan Generic Market
102. Takeda -Datablock
103. Takeda -Antidepressants – Ww Competitive Landscape
104. Takeda -PhIII Data Summary- Vortioxetine
105. Takeda -Antidepressants: Key Pipeline Candidates And
Issues
106. Takeda -Antidepressants Market In Japan
107. Takeda -Key Attributes Of Major Anti-Diabetic Drugs
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
108. Takeda -Advantage, Disadvantage Of Key Anti-Diabetic
109. Drugs
105.akeda -Antidepressants: Key Pipeline Candidates And
Issues
106. Takeda -Antidepressants Market In Japan
107. Takeda -Key Attributes Of Major Anti-Diabetic Drugs
108. Takeda -Advantage, Disadvantage Of Key Anti-Diabetic
109. Drugs
111. Takeda -Tak-875 Ph II Trial Design
112. Datablock
113. Reforms In 2012 And Implications
114. Towa Vs. Key Competitors Sales Break Up Key
115. Foreign Companies Entry In Japan Generic Market
116. Revenue Growth Of Generic Cos. In Price Cut Years
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
Annexures
1. Key Milestones- Japan Pharma
2. Japan Generic Market Model
3. Top 25 Products Vs. Generic Threat
4. Daiichi Sanky-- - Domestic Pharma Sales Trend
5. Mitsubishi Tanabe - Long Listed Product Sales As % Of Total Domestic
Sales
6. Shionogi - Viking- PhII Findings
7. Shionogi - Spring- PhIII Findings
8. Shionogi - Single- PhIII Findings
9. Shionogi - Dolutegravir PhIII Program
10. Eisai - Consolidated Income Statement: MPe Vs. Hayabusa
11. Eisai - Domestic Pharma Sales
12. Eisai - Belviq Cost T-- Eisai
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
13. Astellas - Xtandi: NPV Shrinks Due T-- Commercialization Agreement
14. Chugai - Possibilities Of Roche Increasing Its Stake In Chugai Are Real &
High
15. Chugai - Roche-Chugai: Maturing Relationship Timeline
16. Chugai - Potential Benefits T-- Roche By Increasing Stake In Chugai
17. Chugai - Widening Prospects Of Actemra
18. Chugai - Domestic Japan Pharma Sales
19. Dainippon Sumitom-- – Dainippon Sumitomo- Key Pipeline Candidates
20. Dainippon Sumitom-- - Dainippon Sumitomo-Key Pipeline Candidates
21. Sawai - Generic Companies: Relative Standing
22. Takeda - Key Pipeline Candidates
110. Takeda -Ongoing Clinical Trials Of Tak-875
111. Takeda -Tak-875 Ph II Trial Design
112. Datablock
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
113. Reforms In 2012 And Implications
114. Towa Vs. Key Competitors Sales Break Up Key
115. Foreign Companies Entry In Japan Generic Market
116. Revenue Growth Of Generic Cos. In Price Cut Years
Annexures
1. Key Milestones- Japan Pharma
2. Japan Generic Market Model
3. Top 25 Products Vs. Generic Threat
4. Daiichi Sanky-- - Domestic Pharma Sales Trend
5. Mitsubishi Tanabe - Long Listed Product Sales As % Of Total Domestic
Sales
6. Shionogi - Viking- PhII Findings
7. Shionogi - Spring- PhIII Findings
8. Shionogi - Single- PhIII Findings
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
9. Shionogi - Dolutegravir PhIII Program
10. Eisai - Consolidated Income Statement: MPe Vs. Hayabusa
11. Eisai - Domestic Pharma Sales
12. Eisai - Belviq Cost T-- Eisai
13. Astellas - Xtandi: NPV Shrinks Due T-- Commercialization Agreement
14. Chugai - Possibilities Of Roche Increasing Its Stake In Chugai Are Real &
High
15. Chugai - Roche-Chugai: Maturing Relationship Timeline
16. Chugai - Potential Benefits T-- Roche By Increasing Stake In Chugai
17. Chugai - Widening Prospects Of Actemra
18. Chugai - Domestic Japan Pharma Sales
19. Dainippon Sumitom-- – Dainippon Sumitomo- Key Pipeline Candidates
20. Dainippon Sumitom-- - Dainippon Sumitomo-Key Pipeline Candidates
21. Sawai - Generic Companies: Relative Standing
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
22. Takeda - Key Pipeline Candidates
104. Tada -PhIII Data Sumy- Vortioxetine
105. Takeda -Antidepressants: Key Pipeline Candidates And
Issues
106. Takeda -Antidepressants Market In Japan
107. Takeda -Key Attributes Of Major Anti-Diabetic Drugs
108. Takeda -Advantage, Disadvantage Of Key Anti-Diabetic
109. Drugs
110. Takeda -Ongoing Clinical Trials Of Tak-875
111. Takeda -Tak-875 Ph II Trial Design
112. Datablock
113. Reforms In 2012 And Implications
114. Towa Vs. Key Competitors Sales Break Up Key
115. Foreign Companies Entry In Japan Generic Market
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
116. Revenue Growth Of Generic Cos. In Price Cut Years
Annexures
1. Key Milestones- Japan Pharma
2. Japan Generic Market Model
3. Top 25 Products Vs. Generic Threat
4. Daiichi Sanky-- - Domestic Pharma Sales Trend
5. Mitsubishi Tanabe - Long Listed Product Sales As % Of Total Domestic
Sales
6. Shionogi - Viking- PhII Findings
7. Shionogi - Spring- PhIII Findings
8. Shionogi - Single- PhIII Findings
9. Shionogi - Dolutegravir PhIII Program
10. Eisai - Consolidated Income Statement: MPe Vs. Hayabusa
11. Eisai - Domestic Pharma Sales
Table of ContentsTable of Contents
Reports Cornerwww.reportscorner.com
12. Eisai - Belviq Cost T-- Eisai
13. Astellas - Xtandi: NPV Shrinks Due T-- Commercialization Agreement
14. Chugai - Possibilities Of Roche Increasing Its Stake In Chugai Are Real &
High
15. Chugai - Roche-Chugai: Maturing Relationship Timeline
16. Chugai - Potential Benefits T-- Roche By Increasing Stake In Chugai
17. Chugai - Widening Prospects Of Actemra
18. Chugai - Domestic Japan Pharma Sales
19. Dainippon Sumitom-- – Dainippon Sumitomo- Key Pipeline Candidates
20. Dainippon Sumitom-- - Dainippon Sumitomo-Key Pipeline Candidates
21. Sawai - Generic Companies: Relative Standing
22. Takeda - Key Pipeline Candidates
For more informationFor more information
Reports Cornerwww.reportscorner.com
For more information please visit our website
https://www.reportscorner.com/reports/10015/Global-Pharmaceutical-&-
Biotechnology-Outlook-2013:-Japan-Pharma/
Reports Corner
Thank YouThank You
www.reportscorner.com
RC
Contact us: contact@reportscorner.com

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Global pharmaceutical & biotechnology outlook 2013 japan pharma - Reports Corner

  • 1. RC Reports Corner Global Pharmaceutical & Biotechnology Outlook 2013: Japan Pharma
  • 2. DescriptionDescription Reports Cornerwww.reportscorner.com The coming years will see Japan pharma regaining its status as innovator driven with Edoxaban for Daiichi Sankyo, Canagliflozin for Mitsubishi Tanabe, and Dolutegravir for Shionogi bringing the good times back for the respective companies in 2013 and carrying enough potential to change global market dynamics in the anticoagulant, diabetes and HIV space resp. We think that the massive ~$45b poured in acquiring innovation by Japanese companies does not justify its value as we find that the key catalysts from Japan are in-house candidates.
  • 3. Brief SummaryBrief Summary Reports Cornerwww.reportscorner.com The coming years will see Japan pharma regaining its status as innovator driven with Edoxaban for Daiichi Sankyo, Canagliflozin for Mitsubishi Tanabe, and Dolutegravir for Shionogi bringing the good times back for the respective companies in 2013 and carrying enough potential to change global market dynamics in the anticoagulant, diabetes and HIV space resp. We think that the massive ~$45b poured in acquiring innovation by Japanese companies does not justify its value as we find that the key catalysts from Japan are in-house candidates. Changing political scenario in Japan will accelerate the pace of reforms in Japan as recently; the Liberal Democratic Party (LDP) of Japan came back into power replacing the short tenure of the Democratic Party of Japan (DPJ). LDP was the pioneer initiator of major healthcare reforms with a focus on curbing healthcare costs by means of enhancing generic drugs penetration. Our report discusses in details about the implications of these changes on Innovator and generic domestic Japanese pharma companies.
  • 4. Brief SummaryBrief Summary Reports Cornerwww.reportscorner.com Global companies on the other hand are going to see a favorable scenario in coming years - expected launches in 2013-2014 from global companies will increase competition to domestic players mainly in the respiratory, oncology and rheumatoid arthritis therapy areas, and will increase overall market size of Diabetes and Osteoporosis markets. Going forward, for 2013 –Generic companies will continue to witness a growth story, we think that the recent incentives to promote generic uptake have played out well and at current levels, we do not see meaningful growth until early 2014 when new set of incentives will start playing off. However, in the related space – drug chain stores and biogenerics are two new arenas which we see as next growth drivers – we have analyzed these two novel spaces as well in this report.
  • 5. Brief SummaryBrief Summary Reports Cornerwww.reportscorner.com The detailed 146 pages report on Japan Pharma contains: I. Performance in 2012 – The Hits & Misses II. Japan Pharma: Looking forward in 2013 and beyond Stand on individual companies Changing political scenario is likely to accelerate the pace of reforms III. Analysis on Innovators Companies – Innovation and consolidation continue to serve as catalyst Rich looking pipeline could be delusive Key R&D catalysts from Japan pharma Key upcoming milestones Expected upcoming launches from global companies in Japan and its implications Likely implications of recent consolidation activities Sustainability thru increasing overseas base IV. Analysis on Generic Companies
  • 6. Brief SummaryBrief Summary Reports Cornerwww.reportscorner.com 2012 – price cuts & implications New layer of reforms playing out well Dominance of big players in dispensing pharmacy Shrinking general practitioners market DPC hospitals are a new growth avenue V. Analysis on Drug Chain Stores Macro forces favoring Drug Chain Stores Success story from a few, likely to be replicated by followers VI. Analysis on Biogeneric Companies Evolving Biogenerics space in Japan IN-DEPTH COMPANY ANALYSIS AND REPORTS ON Daiichi Sankyo- Edoxaban will bequeath wings to the price Kyorin – Respiratory Franchise Strengthening Up Mitsubishi Tanabe- Canagliflozin is key, but other drivers also in queue Shionogi- Dolutegravir brings the good times back
  • 7. Brief SummaryBrief Summary Reports Cornerwww.reportscorner.com Eisai- 'HAYABUSA' challenging to achieve despite new approvals Astellas- Defensive Agreements dilute Catalysts Value Chugai – Growth story well built in price Dainippon Sumitomo- Expectation from Latuda are well built in Kyowa Hakko Kirin- Upside from Potelligent technology is still away Nippon Chemiphar - Thin margins, wavering profitability outlook Sawai- Wait until next price cuts Takeda- EU Aspirations are hard to attain Towa- Solid fundamentals not sizeable in near term KEY INDUSTRY TABLES/ ANNEXURES: Japan Pharma Valuation Key Pipeline Candidates- Japan Pharma Global Companies expected major launches in Japan- 2013/14 Consolidation activities major M & A in Japan- Last 5 Years Reforms in 2012 and Implications
  • 8. Brief SummaryBrief Summary Reports Cornerwww.reportscorner.com Revised Incentives for Pharmacies Looming Generic Opportunity Japan Generic segments Drug Chain stores- Profitability Trends Key Milestones Japan Generic Market Model Top 25 Products vs. Generic Threat
  • 9. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com I. Performance in 2012 – The Hits & Misses II. Japan Pharma: Looking forward in 2013 and beyond -- Stand on individual companies -- Changing political scenari-- is likely t-- accelerate the pace of reforms III. Analysis on Innovators Companies – Innovation and consolidation continue t-- serve as catalyst -- Rich Looking Pipeline Could be delusive -- Key R&D catalysts from Japan pharma -- Key upcoming milestones -- Expected upcoming launches from global companies in Japan and its implications -- Likely implications of recent consolidation activities -- Sustainability thru increasing overseas base
  • 10. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com IV. Analysis on Generic Companies -- 2012 – price cuts & implications -- New layer of reforms playing out well -- Dominance of big players in dispensing pharmacy -- Shrinking general practitioners market -- DPC hospitals are new growth avenue V. Analysis on Drug Chain Stores -- Macr-- forces favoring Drug Chain Stores -- Success story from a few, likely t-- be replicated by followers VI. Analysis on Biogeneric Companies -- Evolving Biogenerics space in Japan Japan Pharma - Company Analysis 1. DAIICHI SANKY-- (4569): Edoxaban Will Bequeath Wings T-- The Price!
  • 11. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com • Sum of parts valuation • Lixiana/Edoxaban-Has Key Differentiating Features • Key clinical data analysis • Denosumab: Will Contribute T-- Bottom Lines Despite Partnering • Worst Is Priced In For Ranbaxy Performance • Daiichi Sanky-- Espha (DSE) - A Game Changer In Japan Generic Market 2. KYORIN (4569): Respiratory Franchise Strengthening Up! • Catalyst t-- strengthen respiratory frenchise • KRP-108 – The key driver • Kipres Continues T-- Drive Growth In Anti-Asthmatic Market • Uritos Sales Ramping Up Well • Rapport with GPs Keeps Mucodyne Sales Stable: • Key In-House Candidates Look For Partners 3. MITSUBISHI TANABE (4508): Canagliflozin is Key, But Other Drivers
  • 12. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com Als-- In Queue! • Canagliflozin Is Showing Promise Of Better Safety And Efficacy • Canagliflozin : CV Safety Issues Are Manageable • Domestic Business Faces High Long-Listed Exposure, New Catalysts Will Continue T-- Grow • Remicade Franchise And Telavic Will Support Declining Domestic Business • Teneligliptin Set T-- Enjoy Favorable DPPIV Market In Japan • Royalty Income From Gilenya Continues T-- Grow • Avanafil Prospects Depends Upon Vivus Marketing Partner • Higher Dividend Expected During MTP 4. SHIONOGI (4507): Dolutegravir Brings The Good Times Back! • Dolutegravir/comb-- approval likely in 2013 • Dolutegravir - Combination Therapy Offers Wider Opportunity
  • 13. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com • Rapidly Changing HIV Market Dynamics • Strategic Rational of Integrase Inhibitors • Crestor – NRx/TRx Show Better Resilience Post Lipitor Generics • 'Low Margin Domestic Business' is Not Going t-- Change Soon • Pipeline Has Potential but Unlikely t-- Give Breakthroughs in Near Term • US Business – Nothing Left For Further Downside 5. EISAI (4523): 'HAYABUSA' Challenging t-- Achieve Despite New Approvals! • Pipeline Potential Overly Built in Price • Challenges at domestic front will Surface Soon • Biomarker's Upside Is 'beyond HAYABUSA timeline' • Aricept Lifecycle Management Programs Unlikely t-- Meet Management's Target • Halaven clinical data is encouraging for triple negative breast cancer
  • 14. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com • Fycompa prospects in US are limited due t-- genericization of the market • Belviq label will restrict its peak sales and agreement with Arena leaves little on bottom line 6. ASTELLAS (4503): Defensive Agreements Dilute Catalysts' Value! • Enzalutamide: 2013/14 Will Unfold Potential • Myrbetriq Launch Will Help Maintaining Leadership In The OAB Space • Tivozanib US Approval In RCC Is Likely But Has Limited Potential • ASP-015k Finds A Strong Partner • ASP-015k Deal Summary 7. CHUGAI (4519): Growth Story Well Built In Price! • Actemra T-- Gradually Increase Its Patient Base • Pertuzumab Will Secure Approval In Japan • T-DMI Us Approval In Second Line Breast Cancer Is Likely • Safe Domestic Business And Sales Ramp Up Of Newly Launched Products
  • 15. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com • Roche's Possible Course Of Actions For Increasing Stake In Chugai 8. DAINIPPON SUMITOM-- (4506): Expectations From Latuda Are Well Built In! • LATUDA continue t-- succeed • High Unmet Need Still Exists In The Anti-Psychotics Market • Other Pipeline Candidates 9. KYOWA HAKK-- KIRIN (4151): Upside From Potelligent Technology Is Still Away! • Potelligent technology still a away from fetching premium • Business Restructuring Brings Focus on Pharma Business • Tivantinib Looses Its Commercial Attractiveness • KW-0761 – First Potelligent Based Antibody in Market 10. NIPPON CHEMIPHAR (4539): Thin Margins, Wavering Profitability Outlook!
  • 16. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com • Lowest Profitability Structure Is Not Going T-- Change Soon • Increasing DPC hospitals are biggest driver 11. SAWAI (4555): Wait Until Next Price Cuts! • Excellent Reach in DP Segment is Advantageous • DPC Opportunity is Yet t-- be Tapped • Bio-Similars Opportunity Placed Aside for Now • Premium valuation vs. Peers is Likely t-- be Maintained • Emerging Threats T-- Domestic Generic Companies 12. TAKEDA (4502): EU Aspirations Are Hard t-- Attain! • Increasing competition in DPPIV inhibitors class • Global approval of SYR-322 and its combination is still awaited • EDARBI – 'Me Too' ARB Will Alleviate Pain of Atacand Revenue Loss • Tofacitinib JP Approval will strengthen its RA portfolio • Nycomed acquisition helps deliver the growth and negate Actos patent expiry
  • 17. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com • Key Global late stage Pipeline Candidates • Vortioxetine US approval is likely • Key candidates from Millennium • TAK-875 Data in 'The Lancet' - First GPR-40 agonist Can Potentially Alter Diabetes Therapy Paradigm, Though a Few Questions Remain Unanswered 13. TOWA (4553): Solid Fundamentals Not Sizeable In Near Term! • Modest Sales sustainability from Dispensing Pharma • Ambitious Investment Plans T-- Meet Future Demand • Emerging Threats T-- Domestic Generic Companies List of Charts 1. Generic Penetration Trend 2. Key Generic Companies: Sales Break Up 3. Anticoagulants Market-2009 Vs. 2020
  • 18. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 4. Spring- PhIII Findings (1) 5. Spring- PhIII Findings (2) 6. Dolutegravir PhIII Program 7. E-5501 - Short And Long Term Platelet Responses 8. Asp015k – Changes From Baseline In PASI At Day 42 9. Latuda: Monthly TRx Trend – Us 10. Atypical Anti-Psychotics Market 11. Atypical Anti-Psychotics – Competitive Landscape 12. Japan: Long Listed Drugs And Generic Penetration (2012) 13. Tak-875 PhII Efficacy Data 14. Type 2 Diabetes Market List of Tables 1. Report Card – 2012 (Japan Pharma Stock Performance Hit & Miss) 2. Japan Pharma Valuation
  • 19. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 4. Key Pipeline Candidates- Japan Pharma 5. Global Companies Expected Major Launches In Japan- 2013/14 6. Consolidation Activities Major M&A In Japan - Last 5 Years 7. Japanese Global Cos Overseas Sales 8. JP Companies Performance Vs. US/EU 9. Reforms In 2012 And Implications 10. Revised Incentives For Pharmacies 11. Looming Generic Opportunity 12. Key Generic Companies: Sales Break Up 13. Generic Companies: Relative Standing 14. Japan Generic: Segments 15. Drug Chain Stores: Profitability Trend 16. Biogenerics Opportunities In Japan 17. Daiichi Sankyo: Datablock 18. Daiichi Sankyo: Sum Of Parts
  • 20. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 19. Daiichi Sankyo: Key Milestones 20. Daiichi Sankyo: Relative Clinical Profile Of Xarelto, Eliquis And Edoxaban In SPAF 21. Daiichi Sankyo: Different Geographies 22. Daiichi Sankyo: Edoxaban PhII Clinical Study In SPAF: Global; Japan; Taiwan 23. Daiichi Sankyo: Baseline Characteristics Comparison Of Pivotal Trials In SPAF 24. Daiichi Sankyo: Comparison Of Available Osteoporosis Treatments 25. Daiichi Sankyo: Ranmark (Denosumab) - Development Status In Japan 26. Daiichi Sankyo: Comparison Between Zometa And Denosumab In Oncology 27. Daiichi Sankyo: RBXY: Datablock 28. Daiichi Sankyo: Daiichi Sanky-- Espha Approvals
  • 21. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 29. Kyorin - Datablock 30. Kyorin -Key Milestones 31. Kyorin -KRP-108: Relating Composition 32. Kyorin -Kipres: Competitive Landscape In Japan 33. Kyorin - Japanese OBS Market 34. Mitsubishi Tanabe - Datablock 35. Mitsubishi Tanabe - Key Milestones 36. Mitsubishi Tanabe – SGLT2 Pipeline (Japan And Global Status) 37. Mitsubishi Tanabe – SGLT2 Inhibitors- Clinical Data Comparison 38. Mitsubishi Tanabe - Key Products 39. Mitsubishi Tanabe - Japan RA Market 40. Mitsubishi Tanabe - HCV Pipeline (Japan) 41. Mitsubishi Tanabe - Marketed DPP4 In Japan 42. Mitsubishi Tanabe - DPP4 Pipeline* (Japan And Global Status)
  • 22. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 42. Mitsubishi Tanabe - DPP4 Pipeline* (Japan And Global Status) 43. Mitsubishi Tanabe - Avanafil : Relative Positioning 44. Mitsubishi Tanabe - Dividend Estimates 45. Mitsubishi Tanabe - Key Pipeline Candidates 46. Shionogi - Datablock 47. Shionogi - Key Milestones 48. Shionogi - Single Trial Data 49. Shionogi - Dolutegravir – PhIII Trials 50. Shionogi - HIV Marketed Drugs 51. Shionogi - HIV Pipeline Drugs 52. Shionogi - Spring-2 Trial Data 53. Shionogi - Dolutegravir NPV- Shionogi 54. Eisai - Datablock 55. Eisai - Key Milestones 56. Eisai - Key Pipeline Candidates
  • 23. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 57. Eisai - Aricept WW Sales Projections 58. Eisai - Aricept Sales In Japan: Strength Wise 59. Eisai - Halaven – A Number Of Indications Underway 60. Eisai - Upcoming Competitors For Halaven 61. Eisai - Fycompa Clinical Data 62. Eisai - Data Presented At IEC Annual Meeting 2011 63. Eisai - Eritoran Vs. Xigris: Comparative Efficacy 64. Astellas - Datablock 65. Astellas - Key Milestones 66. Astellas - Long-Term PhI/II Follow-Up Results 67. Astellas - Overactive Bladder Syndrome: Key Drugs 68. Astellas - Mirabegron Efficacy And Tolerability Results In European And Australian Patients 69. Astellas - Mirabegron Efficacy And Tolerability Results In North American Patients 70. Astellas - Competitive Landscape: Advanced Renal Cell Carcinoma
  • 24. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 71. Astellas - Select Oral Ra/Psoriasis Drugs In Development 72. Chugai - Datablock 73. Chugai - Key Milestones 74. Chugai - Actemra - Ongoing Global Trials 75. Chugai - Japan RA Market 76. Chugai - Efficacy And Safety Comparison Of TDM1 Vs. Trastuzumab+Docetaxel In First Line BC TDM1: Ongoing Important Clinical Studies Of T-DM1 In Late Stage Her 2 Positive Breast Cancer 77. Chugai - Chugai-Sales Break Up 78. Dainippon Sumitom-- - Datablock 79. Dainippon Sumitom-- - Key Milestones 80. Dainippon Sumitom-- - Psychiatrists See High Unmet Need 81. Dainippon Sumitom-- - Lurasidone - Ongoing/Planned Clinical Studies 82. Dainippon Sumitom-- - Pearl 2 Data
  • 25. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 83. Dainippon Sumitom-- - Pearl 3 Vs. Seroquel: Overall- A Good Risk/Benefit Ratio 84. Dainippon Sumitom-- - Latuda SWOT Analysis 85. Dainippon Sumitom-- - Pearl 3 Extension Study Data- Non Inferior To Seroquel XR 86. Dainippon Sumitom-- - Dainippon Sumitomo-Key Pipeline Candidates 87. KHK - Datablock 88. KHK - Key Milestones 89. KHK -Potelligent Technology 90. KHK -Segment Classification 91. KHK -Income Statement 92. KHK -Pharma Sales Trend 93. Nippon Chemiphar - Datablock 94. Nippon Chemiphar - Entry Of Foreign Companies In Japan Generic Market
  • 26. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 95. Nippon Chemiphar - Generic Companies: Relative Valuation 96. Sawai - Datablock 97. Sawai - Excellent Reach In Various Markets 98. Sawai - Reforms In 2012 And Implications 99. Sawai - Sawai Vs. Key Competitors Sales Break Up Key 100. Sawai - Generic Companies: Relative Valuation 101. Sawai - Foreign Companies Entry In Japan Generic Market 102. Takeda -Datablock 103. Takeda -Antidepressants – Ww Competitive Landscape 104. Takeda -PhIII Data Summary- Vortioxetine 105. Takeda -Antidepressants: Key Pipeline Candidates And Issues 106. Takeda -Antidepressants Market In Japan 107. Takeda -Key Attributes Of Major Anti-Diabetic Drugs
  • 27. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 108. Takeda -Advantage, Disadvantage Of Key Anti-Diabetic 109. Drugs 105.akeda -Antidepressants: Key Pipeline Candidates And Issues 106. Takeda -Antidepressants Market In Japan 107. Takeda -Key Attributes Of Major Anti-Diabetic Drugs 108. Takeda -Advantage, Disadvantage Of Key Anti-Diabetic 109. Drugs 111. Takeda -Tak-875 Ph II Trial Design 112. Datablock 113. Reforms In 2012 And Implications 114. Towa Vs. Key Competitors Sales Break Up Key 115. Foreign Companies Entry In Japan Generic Market 116. Revenue Growth Of Generic Cos. In Price Cut Years
  • 28. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com Annexures 1. Key Milestones- Japan Pharma 2. Japan Generic Market Model 3. Top 25 Products Vs. Generic Threat 4. Daiichi Sanky-- - Domestic Pharma Sales Trend 5. Mitsubishi Tanabe - Long Listed Product Sales As % Of Total Domestic Sales 6. Shionogi - Viking- PhII Findings 7. Shionogi - Spring- PhIII Findings 8. Shionogi - Single- PhIII Findings 9. Shionogi - Dolutegravir PhIII Program 10. Eisai - Consolidated Income Statement: MPe Vs. Hayabusa 11. Eisai - Domestic Pharma Sales 12. Eisai - Belviq Cost T-- Eisai
  • 29. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 13. Astellas - Xtandi: NPV Shrinks Due T-- Commercialization Agreement 14. Chugai - Possibilities Of Roche Increasing Its Stake In Chugai Are Real & High 15. Chugai - Roche-Chugai: Maturing Relationship Timeline 16. Chugai - Potential Benefits T-- Roche By Increasing Stake In Chugai 17. Chugai - Widening Prospects Of Actemra 18. Chugai - Domestic Japan Pharma Sales 19. Dainippon Sumitom-- – Dainippon Sumitomo- Key Pipeline Candidates 20. Dainippon Sumitom-- - Dainippon Sumitomo-Key Pipeline Candidates 21. Sawai - Generic Companies: Relative Standing 22. Takeda - Key Pipeline Candidates 110. Takeda -Ongoing Clinical Trials Of Tak-875 111. Takeda -Tak-875 Ph II Trial Design 112. Datablock
  • 30. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 113. Reforms In 2012 And Implications 114. Towa Vs. Key Competitors Sales Break Up Key 115. Foreign Companies Entry In Japan Generic Market 116. Revenue Growth Of Generic Cos. In Price Cut Years Annexures 1. Key Milestones- Japan Pharma 2. Japan Generic Market Model 3. Top 25 Products Vs. Generic Threat 4. Daiichi Sanky-- - Domestic Pharma Sales Trend 5. Mitsubishi Tanabe - Long Listed Product Sales As % Of Total Domestic Sales 6. Shionogi - Viking- PhII Findings 7. Shionogi - Spring- PhIII Findings 8. Shionogi - Single- PhIII Findings
  • 31. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 9. Shionogi - Dolutegravir PhIII Program 10. Eisai - Consolidated Income Statement: MPe Vs. Hayabusa 11. Eisai - Domestic Pharma Sales 12. Eisai - Belviq Cost T-- Eisai 13. Astellas - Xtandi: NPV Shrinks Due T-- Commercialization Agreement 14. Chugai - Possibilities Of Roche Increasing Its Stake In Chugai Are Real & High 15. Chugai - Roche-Chugai: Maturing Relationship Timeline 16. Chugai - Potential Benefits T-- Roche By Increasing Stake In Chugai 17. Chugai - Widening Prospects Of Actemra 18. Chugai - Domestic Japan Pharma Sales 19. Dainippon Sumitom-- – Dainippon Sumitomo- Key Pipeline Candidates 20. Dainippon Sumitom-- - Dainippon Sumitomo-Key Pipeline Candidates 21. Sawai - Generic Companies: Relative Standing
  • 32. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 22. Takeda - Key Pipeline Candidates 104. Tada -PhIII Data Sumy- Vortioxetine 105. Takeda -Antidepressants: Key Pipeline Candidates And Issues 106. Takeda -Antidepressants Market In Japan 107. Takeda -Key Attributes Of Major Anti-Diabetic Drugs 108. Takeda -Advantage, Disadvantage Of Key Anti-Diabetic 109. Drugs 110. Takeda -Ongoing Clinical Trials Of Tak-875 111. Takeda -Tak-875 Ph II Trial Design 112. Datablock 113. Reforms In 2012 And Implications 114. Towa Vs. Key Competitors Sales Break Up Key 115. Foreign Companies Entry In Japan Generic Market
  • 33. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 116. Revenue Growth Of Generic Cos. In Price Cut Years Annexures 1. Key Milestones- Japan Pharma 2. Japan Generic Market Model 3. Top 25 Products Vs. Generic Threat 4. Daiichi Sanky-- - Domestic Pharma Sales Trend 5. Mitsubishi Tanabe - Long Listed Product Sales As % Of Total Domestic Sales 6. Shionogi - Viking- PhII Findings 7. Shionogi - Spring- PhIII Findings 8. Shionogi - Single- PhIII Findings 9. Shionogi - Dolutegravir PhIII Program 10. Eisai - Consolidated Income Statement: MPe Vs. Hayabusa 11. Eisai - Domestic Pharma Sales
  • 34. Table of ContentsTable of Contents Reports Cornerwww.reportscorner.com 12. Eisai - Belviq Cost T-- Eisai 13. Astellas - Xtandi: NPV Shrinks Due T-- Commercialization Agreement 14. Chugai - Possibilities Of Roche Increasing Its Stake In Chugai Are Real & High 15. Chugai - Roche-Chugai: Maturing Relationship Timeline 16. Chugai - Potential Benefits T-- Roche By Increasing Stake In Chugai 17. Chugai - Widening Prospects Of Actemra 18. Chugai - Domestic Japan Pharma Sales 19. Dainippon Sumitom-- – Dainippon Sumitomo- Key Pipeline Candidates 20. Dainippon Sumitom-- - Dainippon Sumitomo-Key Pipeline Candidates 21. Sawai - Generic Companies: Relative Standing 22. Takeda - Key Pipeline Candidates
  • 35. For more informationFor more information Reports Cornerwww.reportscorner.com For more information please visit our website https://www.reportscorner.com/reports/10015/Global-Pharmaceutical-&- Biotechnology-Outlook-2013:-Japan-Pharma/
  • 36. Reports Corner Thank YouThank You www.reportscorner.com RC Contact us: contact@reportscorner.com