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World Market for Addiction Disorders, 2009                                                                             - 2016: The Future
Therapies for Substance Dependence and Impulse Control
Published on October 2009

                                                                                                                             Report Summary

A comprehensive update of the 2005 edition
Examines the market for addiction pharmacotherapies currently estimated at US$2 billion
The substance dependence field is transforming into a high-growth market opportunity. Supported by the success of Pfizer's recently
launched Chantix/Champix, which is on track for blockbuster status in the smoking cessation sector, pharmacotherapies in
development for alcohol, narcotic, and nicotine dependencies are poised to radically change the addiction treatment landscape in this
difficult-to-treat patient population.
The report estimates that the current market for addiction disorders is valued at US$3.2 billion and this is forecast to increase 19% to
US$3.8 billion by 2016.
The World Market for Addiction Disorders, 2009 2016: Future Therapies for Substance Dependence and Impulse Control, will
introduce the reader a specialty pharmaceutical market which is positioned for high-growth based on analysis of marketed and
pipeline drugs, company activities, and addiction disorder demographics.
Therapy area forecasting and illustrative comparative sales data is presented to gain insight into leading products with sales
estimates to 2016.
Objectives of Report


The objectives of this 80 page report are to provide an in-depth analysis of the global addiction pharmacotherapeutic market. Included
in this study are analyses of key therapy areas, R&D programs, and innovating companies and products. The reader will benefit from
market forecasts, pooled knowledge of recent industrial activities and events, and from analytical discourse, which is intended to
stimulate growth and create new market opportunities.


Report Highlights Include:



'The current market for addiction disorders is valued at US$3.2 billion, up from US$2 billion in 2005
'Critical analysis of alcohol, cocaine, opiate, and nicotine addictions
'Review of epidemiological, aetiological, and demographic data for addiction disorders
'Analysis of over 10 key marketed products and inclusion of 34 R&D candidates identified in preclinical to clinical stages of
development for addiction disorders
'Sales estimates (US$) to 2012 for major therapy areas
'Strategic insights for life-cycle optimization and product development
'Critical evaluation of leading addiction pharmacotherapies
'Emerging markets identified and sector analysis
'Trend analysis of industry events and activities over past 2 years
'Detailed R&D themes and clusters by addiction area
'Data generation on sector and market values between 2004 and 2012 and therapy forecasts by 2020 (US$)
'High revenue-yielding prospects identified with projected sales estimations
'R&D pipeline positioning for novel candidates
'Market insights for product development and drug promotion



World Market for Addiction Disorders, 2009 - 2016: The Future Therapies for Substance Dependence and Impulse Control                      Page 1/5
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What you can learn from this report:


'Which addiction therapies are the current and potential future market leaders
'How companies are reformulating products for addiction indications
'Which premarket addiction pharmacotherapies are identified as high-value products
'Which companies are developing drugs for addiction disorders
'Sales predictions to 2016 for addiction pharmacotherapies
'What the likely impact of pipeline products will be on value growth of the addiction market over the 10 years
'Which addiction subsectors could be niche market opportunities
'What the future outlook holds for addiction pharmacotherapies
'Insight into R&D trends for alcohol, cocaine, opiate, and nicotine addictions
'Which molecules and compounds are main R&D clusters for dependency disorders
'Which of the pipeline candidates are top prospects in the addiction market over the next decade and to 2025
Report Contains:


'Detailed survey and analysis of the current and future global addiction disorder market
'Comprehensive update on key marketed products indicated for alcohol, narcotic, and nicotine dependency disorders
'Review of epidemiological, demographic, aetiological, and therapeutic data associated with addiction disorders
'Market analysis and insight of key addiction pharmacotherapies and pipelines
'Market value predictions of individual marketed products to 2016
'Insight and trend analysis of pipeline products for addiction disorders
'Review of promising pipeline products and potential market opportunities
'Extensive coverage of the R&D pipeline for addiction disorders
'Guide to leads for potential licensing opportunities


Companies Mentioned in this Report include


Acrux Alkermes Biotie Therapies Brookwood Pharmaceuticals Catalyst Pharma Partners Celtic Pharmaceuticals Cephalon
Drug Abuse Sciences Elbion Eli Lilly Forest Laboratories GlaxoSmithKline Impax Laboratories InterveXion Therapeutics J&J
Janssen-Cilag Krele Pharma Merck Serono Nabi Biopharmaceuticals Pfizer Sanofi-Aventis Somaxon Pharma. STADA
Synosia Therapeutics Targacept Teva Pharmaceuticals Titan Pharmaceuticals WorldMeds Yaupon Therapeutics




                                                                                                                                           Table of Content

Chapter 1. Introduction to Addiction Disorders Addiction: Substance Characteristics and Prevalence of Misuse Neurobiological Basis
of Addiction Prevalence of Substance Misuse - Estimates for North America, Europe and Asia North America United States Canada
Europe Asia (Japan)             Incidence Estimates for Addiction Disorders in North America, Europe, and Japan Treatment Options
Chapter 2. The Addiction Pharmacotherapy Market Market Overview for Addiction Disorders Market Forecasts by Therapeutic Area
Alcohol Addiction Narcotic Addiction Tobacco Addiction                              Chapter 3. Alcohol Addiction Market Alcohol Addiction Acamprosate
(Campral) - Merck Serono/Forest Laboratories Disulfiram (Antabuse) - Alpharma Naltrexone Hydrochloride Alkermes - Reformulated
Naltrexone (Vivitrol)          Pipeline Focus for Alcohol Addiction - Biotie Therapies Corp Nalmefene Naltrexone Depot                             Alcohol Addiction
- Market Insights and Future Considerations                      Chapter 4. The Narcotic Addiction Market Global Narcotics - Usage Statistics Narcotic
Addiction - The Scale of the Problem Pharmacotherapies for Narcotic Addiction - Market Evaluation Opioid Addiction
Pharmacotherapies Drug Substitute Therapies Subutex/Suboxone (Buprenorphine) - Schering-Plough/Reckitt Benckiser Suboxone
Reformulation Methadone                 Drugs to Control Opioid Withdrawal Symptoms BritLofex (Lofexidine); Opizone (Naltrexone) - Britannia
Pharma/STADA Naltrexone Nalorex - Bristol-Myers Squibb Opizone - Britannia                                         Therapeutic Switching in Addiction Markets Outlook
for Pharmacotherapeutic Markets Related to Alcohol and Narcotic Abuse                                     Chapter 5. Tobacco Addiction Prevalence and Mortality
Statistics Nicotine: Mechanism of Action Tobacco Dependence and Smoking Cessation Smoking and Health Consequences


World Market for Addiction Disorders, 2009 - 2016: The Future Therapies for Substance Dependence and Impulse Control                                         Page 2/5
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Healthcare Costs of Smoking Addiction                      Tobacco Addiction Pharmacotherapeutics Market Analysis of Smoking Cessation
Pharmacotherapeutics Nicotine Replacement Therapies Nicorette/Nicotrol - McNeil Healthcare/Johnson & Johnson Sales Estimates
NiQuitin/NicoDerm/Nicorette/Nicabate - GlaxoSmithKline Sales Estimates Nicotinell/Habitrol - Novartis Sales Estimates
Neuromodulating Pharmacotherapies for Smoking Cessation Zyban (Bupropion) - GlaxoSmithKline Sales Estimates Champix/Chantix
(Varenicline) - Pfizer Sales Estimates                  Tobacco Addiction - Market Insights and Future Considerations                      Chapter 6. Drugs in
Research and Development Addiction Disorders - Research and Development Overview Pipeline Addiction Pharmacotherapies
Alcohol Dependence Cocaine Dependence Novel Late-Stage Candidates Celtic Pharmaceuticals Synosia Therapeutics/Roche
Cannabis Dependence Immunotherapy Focus - InterveXion Therapeutics                                         Opioid Dependence Late-Stage Development Products
for Opioid Dependence               Impulse Control Disorders Pipeline Focus - Gambling Addiction Tobacco/Nicotine Dependence Pipeline
Focus on Immunotherapies for Tobacco Dependence Nabi Biopharmaceuticals - NicVAX Celtic Pharmaceuticals - TA-NIC
Smoking Cessation - A Transforming Market                         Chapter 7. Market Analysis, Therapy Forecasting, and Prospect Mining Market
Analysis and Therapy Forecasting Therapy Area Forecasts Comparative Analysis: Addiction Pharmacotherapies                                            Prospect Mining
Addiction Disorder Pharmacotherapy Prospects                           Therapy Area Forecasts 2016 and 2025                   Chapter 8. Summary and Key Data
Points on the Addiction Market Key Data Points Reference Sources                                    List of Tables Table 1.1 Neurotransmitter Systems Associated
with Addiction Table 1.2 Drugs of Abuse and their Associations with Neurotransmitter Systems Table 1.3 Estimated Prevalence of
Substance Misuse in Europe, 2009 (000' users) Table 1.4 Estimated Incidence for Addiction Disorders in North America, Europe and
Japan, 2009 (incidence in 000s) Table 2.1 Market Synopsis for Addiction Disorders: Current data Table 2.2 Estimated Global Sales
(US$) and Annual Growth (%) of Key Drugs to Treat Addictions, 2008-2016 Table 3.1 Physiological Consequences of the
Disulfiram-Alcohol Reaction Table 5.1 Estimated Sales (US$) and Annual Growth (%) of Smoking Cessation Therapies, 2008-2016
Table 6.1 Drugs in Development/Trials for Alcohol Dependence, 2009 Table 6.2 Drugs in Development/Trials for Cocaine
Dependence, 2009 Table 6.3 Drugs in Development/Trials for Cannabis Dependence, 2009 Table 6.4 Drugs in Development/Trials
for Ampetamine and Phencyclidine Dependencies, 2009 Table 6.5 Drugs in Development/Trials for Opioid Dependence, 2009 Table
6.6 Drugs in Development/Trials for Impulse Control Disorders, 2009 Table 6.7 Drugs in Development/Trials for Tobacco Addiction,
2009 Table 7.1 Estimated Global Drug Market (US$m) and Growth Rate (%) for Addiction Pharmacotherapies, 2008-2016 Table 7.2
Therapy Area Forecasts for the World Addiction Disorders Market, 2016 and 2025                                         List of Figures Figure 1.1 Estimated Prevalence
of Substance Misuse in United States, 2009 Figure 1.2 stimated Prevalence of Substance Misuse in Canada, 2009 Figure 1.3
Estimated Prevalence of Substance Misuse in Europe, 2009 Figure 1.4 Estimated Prevalence of Substance Misuse in Japan, 2009
Figure 2.1 Estimated Sales (US$) of Addiction Drugs Segmented by Therapeutic Area, 2008-2016 Figure 2.2 Estimated Global Sales
(US$) of Leading Addiction Drugs by Therapy Area, 2009 & 2016 Figure 7.1 Comparative Analysis of Leading Addiction
Pharmacotherapies, 2008-2016 (US$m) Figure 7.2 Key Addiction Disorder Pharmacotherapy Prospects, 2009




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World Market for Addiction Disorders, 2009 - 2016: The Future Therapies for Substance Dependence and Impulse Control

  • 1. Find Industry reports, Company profiles ReportLinker and Market Statistics >> Get this Report Now by email! World Market for Addiction Disorders, 2009 - 2016: The Future Therapies for Substance Dependence and Impulse Control Published on October 2009 Report Summary A comprehensive update of the 2005 edition Examines the market for addiction pharmacotherapies currently estimated at US$2 billion The substance dependence field is transforming into a high-growth market opportunity. Supported by the success of Pfizer's recently launched Chantix/Champix, which is on track for blockbuster status in the smoking cessation sector, pharmacotherapies in development for alcohol, narcotic, and nicotine dependencies are poised to radically change the addiction treatment landscape in this difficult-to-treat patient population. The report estimates that the current market for addiction disorders is valued at US$3.2 billion and this is forecast to increase 19% to US$3.8 billion by 2016. The World Market for Addiction Disorders, 2009 2016: Future Therapies for Substance Dependence and Impulse Control, will introduce the reader a specialty pharmaceutical market which is positioned for high-growth based on analysis of marketed and pipeline drugs, company activities, and addiction disorder demographics. Therapy area forecasting and illustrative comparative sales data is presented to gain insight into leading products with sales estimates to 2016. Objectives of Report The objectives of this 80 page report are to provide an in-depth analysis of the global addiction pharmacotherapeutic market. Included in this study are analyses of key therapy areas, R&D programs, and innovating companies and products. The reader will benefit from market forecasts, pooled knowledge of recent industrial activities and events, and from analytical discourse, which is intended to stimulate growth and create new market opportunities. Report Highlights Include: 'The current market for addiction disorders is valued at US$3.2 billion, up from US$2 billion in 2005 'Critical analysis of alcohol, cocaine, opiate, and nicotine addictions 'Review of epidemiological, aetiological, and demographic data for addiction disorders 'Analysis of over 10 key marketed products and inclusion of 34 R&D candidates identified in preclinical to clinical stages of development for addiction disorders 'Sales estimates (US$) to 2012 for major therapy areas 'Strategic insights for life-cycle optimization and product development 'Critical evaluation of leading addiction pharmacotherapies 'Emerging markets identified and sector analysis 'Trend analysis of industry events and activities over past 2 years 'Detailed R&D themes and clusters by addiction area 'Data generation on sector and market values between 2004 and 2012 and therapy forecasts by 2020 (US$) 'High revenue-yielding prospects identified with projected sales estimations 'R&D pipeline positioning for novel candidates 'Market insights for product development and drug promotion World Market for Addiction Disorders, 2009 - 2016: The Future Therapies for Substance Dependence and Impulse Control Page 1/5
  • 2. Find Industry reports, Company profiles ReportLinker and Market Statistics What you can learn from this report: 'Which addiction therapies are the current and potential future market leaders 'How companies are reformulating products for addiction indications 'Which premarket addiction pharmacotherapies are identified as high-value products 'Which companies are developing drugs for addiction disorders 'Sales predictions to 2016 for addiction pharmacotherapies 'What the likely impact of pipeline products will be on value growth of the addiction market over the 10 years 'Which addiction subsectors could be niche market opportunities 'What the future outlook holds for addiction pharmacotherapies 'Insight into R&D trends for alcohol, cocaine, opiate, and nicotine addictions 'Which molecules and compounds are main R&D clusters for dependency disorders 'Which of the pipeline candidates are top prospects in the addiction market over the next decade and to 2025 Report Contains: 'Detailed survey and analysis of the current and future global addiction disorder market 'Comprehensive update on key marketed products indicated for alcohol, narcotic, and nicotine dependency disorders 'Review of epidemiological, demographic, aetiological, and therapeutic data associated with addiction disorders 'Market analysis and insight of key addiction pharmacotherapies and pipelines 'Market value predictions of individual marketed products to 2016 'Insight and trend analysis of pipeline products for addiction disorders 'Review of promising pipeline products and potential market opportunities 'Extensive coverage of the R&D pipeline for addiction disorders 'Guide to leads for potential licensing opportunities Companies Mentioned in this Report include Acrux Alkermes Biotie Therapies Brookwood Pharmaceuticals Catalyst Pharma Partners Celtic Pharmaceuticals Cephalon Drug Abuse Sciences Elbion Eli Lilly Forest Laboratories GlaxoSmithKline Impax Laboratories InterveXion Therapeutics J&J Janssen-Cilag Krele Pharma Merck Serono Nabi Biopharmaceuticals Pfizer Sanofi-Aventis Somaxon Pharma. STADA Synosia Therapeutics Targacept Teva Pharmaceuticals Titan Pharmaceuticals WorldMeds Yaupon Therapeutics Table of Content Chapter 1. Introduction to Addiction Disorders Addiction: Substance Characteristics and Prevalence of Misuse Neurobiological Basis of Addiction Prevalence of Substance Misuse - Estimates for North America, Europe and Asia North America United States Canada Europe Asia (Japan) Incidence Estimates for Addiction Disorders in North America, Europe, and Japan Treatment Options Chapter 2. The Addiction Pharmacotherapy Market Market Overview for Addiction Disorders Market Forecasts by Therapeutic Area Alcohol Addiction Narcotic Addiction Tobacco Addiction Chapter 3. Alcohol Addiction Market Alcohol Addiction Acamprosate (Campral) - Merck Serono/Forest Laboratories Disulfiram (Antabuse) - Alpharma Naltrexone Hydrochloride Alkermes - Reformulated Naltrexone (Vivitrol) Pipeline Focus for Alcohol Addiction - Biotie Therapies Corp Nalmefene Naltrexone Depot Alcohol Addiction - Market Insights and Future Considerations Chapter 4. The Narcotic Addiction Market Global Narcotics - Usage Statistics Narcotic Addiction - The Scale of the Problem Pharmacotherapies for Narcotic Addiction - Market Evaluation Opioid Addiction Pharmacotherapies Drug Substitute Therapies Subutex/Suboxone (Buprenorphine) - Schering-Plough/Reckitt Benckiser Suboxone Reformulation Methadone Drugs to Control Opioid Withdrawal Symptoms BritLofex (Lofexidine); Opizone (Naltrexone) - Britannia Pharma/STADA Naltrexone Nalorex - Bristol-Myers Squibb Opizone - Britannia Therapeutic Switching in Addiction Markets Outlook for Pharmacotherapeutic Markets Related to Alcohol and Narcotic Abuse Chapter 5. Tobacco Addiction Prevalence and Mortality Statistics Nicotine: Mechanism of Action Tobacco Dependence and Smoking Cessation Smoking and Health Consequences World Market for Addiction Disorders, 2009 - 2016: The Future Therapies for Substance Dependence and Impulse Control Page 2/5
  • 3. Find Industry reports, Company profiles ReportLinker and Market Statistics Healthcare Costs of Smoking Addiction Tobacco Addiction Pharmacotherapeutics Market Analysis of Smoking Cessation Pharmacotherapeutics Nicotine Replacement Therapies Nicorette/Nicotrol - McNeil Healthcare/Johnson & Johnson Sales Estimates NiQuitin/NicoDerm/Nicorette/Nicabate - GlaxoSmithKline Sales Estimates Nicotinell/Habitrol - Novartis Sales Estimates Neuromodulating Pharmacotherapies for Smoking Cessation Zyban (Bupropion) - GlaxoSmithKline Sales Estimates Champix/Chantix (Varenicline) - Pfizer Sales Estimates Tobacco Addiction - Market Insights and Future Considerations Chapter 6. Drugs in Research and Development Addiction Disorders - Research and Development Overview Pipeline Addiction Pharmacotherapies Alcohol Dependence Cocaine Dependence Novel Late-Stage Candidates Celtic Pharmaceuticals Synosia Therapeutics/Roche Cannabis Dependence Immunotherapy Focus - InterveXion Therapeutics Opioid Dependence Late-Stage Development Products for Opioid Dependence Impulse Control Disorders Pipeline Focus - Gambling Addiction Tobacco/Nicotine Dependence Pipeline Focus on Immunotherapies for Tobacco Dependence Nabi Biopharmaceuticals - NicVAX Celtic Pharmaceuticals - TA-NIC Smoking Cessation - A Transforming Market Chapter 7. Market Analysis, Therapy Forecasting, and Prospect Mining Market Analysis and Therapy Forecasting Therapy Area Forecasts Comparative Analysis: Addiction Pharmacotherapies Prospect Mining Addiction Disorder Pharmacotherapy Prospects Therapy Area Forecasts 2016 and 2025 Chapter 8. Summary and Key Data Points on the Addiction Market Key Data Points Reference Sources List of Tables Table 1.1 Neurotransmitter Systems Associated with Addiction Table 1.2 Drugs of Abuse and their Associations with Neurotransmitter Systems Table 1.3 Estimated Prevalence of Substance Misuse in Europe, 2009 (000' users) Table 1.4 Estimated Incidence for Addiction Disorders in North America, Europe and Japan, 2009 (incidence in 000s) Table 2.1 Market Synopsis for Addiction Disorders: Current data Table 2.2 Estimated Global Sales (US$) and Annual Growth (%) of Key Drugs to Treat Addictions, 2008-2016 Table 3.1 Physiological Consequences of the Disulfiram-Alcohol Reaction Table 5.1 Estimated Sales (US$) and Annual Growth (%) of Smoking Cessation Therapies, 2008-2016 Table 6.1 Drugs in Development/Trials for Alcohol Dependence, 2009 Table 6.2 Drugs in Development/Trials for Cocaine Dependence, 2009 Table 6.3 Drugs in Development/Trials for Cannabis Dependence, 2009 Table 6.4 Drugs in Development/Trials for Ampetamine and Phencyclidine Dependencies, 2009 Table 6.5 Drugs in Development/Trials for Opioid Dependence, 2009 Table 6.6 Drugs in Development/Trials for Impulse Control Disorders, 2009 Table 6.7 Drugs in Development/Trials for Tobacco Addiction, 2009 Table 7.1 Estimated Global Drug Market (US$m) and Growth Rate (%) for Addiction Pharmacotherapies, 2008-2016 Table 7.2 Therapy Area Forecasts for the World Addiction Disorders Market, 2016 and 2025 List of Figures Figure 1.1 Estimated Prevalence of Substance Misuse in United States, 2009 Figure 1.2 stimated Prevalence of Substance Misuse in Canada, 2009 Figure 1.3 Estimated Prevalence of Substance Misuse in Europe, 2009 Figure 1.4 Estimated Prevalence of Substance Misuse in Japan, 2009 Figure 2.1 Estimated Sales (US$) of Addiction Drugs Segmented by Therapeutic Area, 2008-2016 Figure 2.2 Estimated Global Sales (US$) of Leading Addiction Drugs by Therapy Area, 2009 & 2016 Figure 7.1 Comparative Analysis of Leading Addiction Pharmacotherapies, 2008-2016 (US$m) Figure 7.2 Key Addiction Disorder Pharmacotherapy Prospects, 2009 World Market for Addiction Disorders, 2009 - 2016: The Future Therapies for Substance Dependence and Impulse Control Page 3/5
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