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IMMUNOLOGY
IMMUNOLOGY?
Immunology is a branch of science
and biology concerned with the
immunity.
Immunology is a combination of
both immunity and immune system.
The word “Immuis” means free from burden
and “immunitas” means exemption from
government taxes and this provided the
English terminology Immunity.
Immunity is a broad definition: This is a
protective or defense mechanism of our
body, which leads us to a healthy life.
IMMUNITY
Inborn or innate immunity: It is present at
birth. This is our First Line Of Defense.
Acquired or specific: It is not present at
birth but becomes part of our immune
system as the lymphoid system develops.
TYPES OF IMMUNITY
Immune system is a collection of organs, tissue, &
soluble factors to defend against bacteria, viruses,
& tumour cells.
Consist of:
Primary (central) lymphoid organs in which
leukocytes develop
Secondary (peripheral) lymphoid organs &
tissues in which immune response occur.
IMMUNE SYSTEM?
The cells of the
immune system
circulate through the
body via lymph and
blood. Pathogens and
their antigens are
transported from
tissues via lymphatic
vessels to the lymph
nodes where they
encounter immune
cells.
CELLS, TISSUES AND ORGANS OF
THE IMMUNE SYSTEM
Immune cells are bone marrow-derived, & distributed
through out the body
Primary lymphoid organs:
Thymus: T cell maturation
Bone marrow (bursa of Fabricius in birds): B cell
maturation
Secondary lymphoid organs:
Lymph nodes
Spleen
Mucosal lymphoid tissues (lung, gut)
Vaccination protects us from infection
by inducing the adaptive immune
response, but by passing the need for
a primary infection
VACCINATION?
Edward Jenner
(1749-1823)
&
The Discovery of
Vaccination (1796)
“Vaccinia
(cowpox)”
&
“human smallpox”
Autoimmunity (SLE, Arthritis,
Myasthenia gravis, Graves disease)
Immunodeficiency (inherited, acquired)
Allergy (environment, drugs)
Cancer (Leukemia, Lymphoma)
Diseases associated with immune
system dysfunction
THERAPEUTICS
Vaccination
Adoptive immunotherapy
Transplantation
Austin Journal of Clinical Immunology

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Austin Journal of Clinical Immunology

  • 2. IMMUNOLOGY? Immunology is a branch of science and biology concerned with the immunity. Immunology is a combination of both immunity and immune system.
  • 3. The word “Immuis” means free from burden and “immunitas” means exemption from government taxes and this provided the English terminology Immunity. Immunity is a broad definition: This is a protective or defense mechanism of our body, which leads us to a healthy life. IMMUNITY
  • 4. Inborn or innate immunity: It is present at birth. This is our First Line Of Defense. Acquired or specific: It is not present at birth but becomes part of our immune system as the lymphoid system develops. TYPES OF IMMUNITY
  • 5. Immune system is a collection of organs, tissue, & soluble factors to defend against bacteria, viruses, & tumour cells. Consist of: Primary (central) lymphoid organs in which leukocytes develop Secondary (peripheral) lymphoid organs & tissues in which immune response occur. IMMUNE SYSTEM?
  • 6.
  • 7. The cells of the immune system circulate through the body via lymph and blood. Pathogens and their antigens are transported from tissues via lymphatic vessels to the lymph nodes where they encounter immune cells.
  • 8. CELLS, TISSUES AND ORGANS OF THE IMMUNE SYSTEM Immune cells are bone marrow-derived, & distributed through out the body Primary lymphoid organs: Thymus: T cell maturation Bone marrow (bursa of Fabricius in birds): B cell maturation Secondary lymphoid organs: Lymph nodes Spleen Mucosal lymphoid tissues (lung, gut)
  • 9. Vaccination protects us from infection by inducing the adaptive immune response, but by passing the need for a primary infection VACCINATION?
  • 10. Edward Jenner (1749-1823) & The Discovery of Vaccination (1796) “Vaccinia (cowpox)” & “human smallpox”
  • 11.
  • 12. Autoimmunity (SLE, Arthritis, Myasthenia gravis, Graves disease) Immunodeficiency (inherited, acquired) Allergy (environment, drugs) Cancer (Leukemia, Lymphoma) Diseases associated with immune system dysfunction