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Ravi Nishankar
Outline
• What is Ultrasound imaging?
• Why Ultrasound?
• Common Uses
• History
• Properties of Ultrasound
• Equipment
• How does the procedure
work?
• Benefits and Risks
What is General Ultrasound Imaging?
• Ultrasound imaging, also called sonography,
involves exposing part of the body to high-
frequency sound waves to produce pictures of the
inside of the body.
• Ultrasound examinations do not use ionizing
radiation (as used in x-rays).
• Because ultrasound images are captured in real-
time, they can show the structure and movement
of the body's internal organs, as well as blood
flowing through blood vessels.
Why Ultrasound
• Ultrasound (US) is the most widely used
imaging technology worldwide
• Popular due to availability, speed, low cost,
patient-friendliness (no radiation)
• Applied in obstetrics, cardiology, inner
medicine, urology,...
• Ongoing research to improve image quality,
speed and new application areas such a intra-
operative navigation, tumour therapy,...
What are some common uses of the
procedure?
1.Ultrasound examinations can help to diagnose
a variety of conditions and to assess organ
damage following illness.
2.Ultrasound is used to help physicians evaluate
symptoms such as:
•pain
•swelling
•infection
•hematuria (blood in urine)
Ultrasound is a useful way of examining many of the body's
internal organs, including but not limited to the:
• heart and blood vessels, including the abdominal aorta and
its major branches
• Liver
• Gallbladder
• Spleen
• Pancreas
• Kidneys
• Bladder
• Uterus, ovaries, and unborn child (fetus) in pregnant
patients
• Eyes
• Thyroid and parathyroid glands
• Scrotum (testicles)
• brain in infants
• hips in infants
Ultrasound is also used to:
•guide procedures such as needle biopsies, in
which needles are used to extract sample cells
from an abnormal area for laboratory testing.
•image the breasts and to guide biopsy of breast
cancer
•diagnose a variety of heart conditions and to
assess damage after a heart attack or diagnose
for valvular heart disease.
Doppler ultrasound images can help the
physician to see and evaluate:
• blockages to blood flow (such as clots).
• narrowing of vessels (which may be caused by
plaque).
• tumors and congenital vascular malformation.
With knowledge about the speed and volume of
blood flow gained from a Doppler ultrasound
image, the physician can often determine
whether a patient is a good candidate for a
procedure like angioplasty.
Applications in Obstetrics
• Follow fetal development
• Detect pathologies
Two-dimensional B-mode Ultrasound image of a
fetus
Defused liver with abscess
General Radiology
Carotid Artery with Color Doppler
Three-dimensional image of the
same fetus ~ 5 months after
conception
Applications in Cardiology
•Blood flow in vessels (Doppler US)
•Contraction, Rhythm
•Blood flow in the heart (defects on wall muscle, valve
defects
•Assessment of cardiac perfusion
sti
Applications in Inner Medicine
•Gallstone
•Perfusion of renal
transplant
Gallstone (red arrow) within the gallbladder produces a bright
surface echo and causes a dark acoustic shadow (S)
Perfusion Doppler image of a renal
transplant
Applications in Musculoskeletal System
• Visualisation of tendons, ligaments
• Investigations under movement is possible – simplifies
the detection of ruptures, obstructions…
The arrows show the large gap of the rupture Achilles
tendon
US image of ISS astronaut Mike Fincke's biceps tendon, where
"D" denotes the deltoid muscle and "T" is the proximal
intracapsular end of the long biceps tendon
Applications of Ultrasound
Elastography
US Elastography is often used to classify tumours. Malignant tumours
are 10 to 100 times stiffer than the normal soft tissue
around
History
The bat use Ultrasound for navigation
History
• 1877: Lord Raleigh - "Theory of Sound"
• 1880: Pierre & Jacques Curie - Piezoelectric
effect
• 1914: Langevin - First Ultrasound generator
using piezoelectric effect
• 1928: Solokov - Ultrasound for material
testing
• 1942: Dussik - First application of Ultrasound
in medical diagnostics
• Shortly after WWII, researchers in Japan
began to explore medical diagnostic
capabilities of ultrasound.
• ... different medical applications (gall stones,
tumours)
• End of 1960's: Boom of Ultrasound in medical
diagnostics
Pan-Scanner - The transducer rotated in a semicircular
arc
around the patient (1957)
Scan converter allowed for the first time to use the
upcoming computer technology to improve US
• Early 1970s
– Gray scale static images of internal organs
•Mid 1970s
– Real-time imaging
•Early 1980s
– Spectral Doppler
– Color Doppler
•Also produced was a hand-held “contact”
scanner for clinical use.
Ultrasound Machines
Development of the B-mode Ultrasound image
quality
Properties of Ultrasound
The frequencies of medical Ultrasound waves are several magnitudes higher than
the upper limit of → human hearing.
Approximate frequency ranges of
sound
• Although ultrasound is better known for its
diagnostic capabilities, it was initially used for
therapy rather than diagnosis.
• In the 1940s, ultrasound was used to perform
services similar to that of radiation or
chemotherapy now.
• Ultrasonic waves emit heat that can create
disruptive effects on animal tissue and
destroy malignant tissue.
Common Sound Frequencies
Sound Frequency
Adult audible range 15 – 20’000 Hz
Range for children's hearing Up to 40’000 Hz
Male speaking voice 100 – 1’500 Hz
Female speaking voice 150 ‘ 2’500 Hz
Standard pitch (Concert A) 44 0 Hz
Bat 50’000 – 200’000 Hz
Medical Ultrasound 2.5 – 40 MHz
Maximum sound frequency 600 MHz
Common sound frequencies and frequency
ranges
Physics of the method
• Longitudinal mechanical waves
• Needs elastic medium
– Transducer needs to be in contact with
skin
• Wave velocity
– Fat -> 1450 m/s
– Muscle ->1580 m/s
Principles of Ultrasound
Its Components
Operations
Applications
Ultrasound Parts
The Ultrasound Machine
A basic ultrasound machine has the following parts:
1.Transducer probe - probe that sends and receives the sound
waves
2.Central processing unit (CPU) - computer that does all of the
calculations and contains the electrical power supplies for itself
and the transducer probe
3.Transducer pulse controls - changes the amplitude, frequency
and duration of the pulses emitted from the transducer probe
4.Display - displays the image from the ultrasound data processed
by the CPU
5.Keyboard/cursor - inputs data and takes measurements from the
display
6.Disk storage device (hard, floppy, CD) - stores the acquired
images
7.Printer - prints the image from the displayed data
Equipment
• Ultrasound scanners consist of a console
containing a computer and electronics, a video
display screen and a transducer that is used to do
the scanning.
• The transducer is a small hand-held device that
resembles a microphone, attached to the
scanner by a cord.
• The transducer sends out inaudible high
frequency sound waves into the body and then
listens for the returning echoes from the tissues
in the body.
• The principles are similar to sonar used by boats
and submarines.
• The ultrasound image is immediately visible
on a video display screen that looks like a
computer or television monitor.
• The image is created based on the amplitude
(strength), frequency and time it takes for the
sound signal to return from the area of the
patient being examined to the transducer
and the type of body structure the sound
travels through.
• Types of Transducer
How does the procedure work?
• Ultrasound imaging is based on the same
principles involved in the sonar used by bats,
ships, fishermen and the weather service.
• When a sound wave strikes an object, it bounces
back, or echoes.
• By measuring these echo waves, it is possible to
determine how far away the object is and its
size, shape and consistency (whether the object
is solid, filled with fluid, or both).
• In medicine, ultrasound is used to detect
changes in appearance of organs, tissues, and
vessels or detect abnormal masses, such as
tumors.
• In an ultrasound examination, a transducer both
sends the sound waves and receives/records
the echoing waves.
• When the transducer is pressed against the skin,
it directs small pulses of inaudible, high-
frequency sound waves into the body.
• As the sound waves bounce off of internal
organs, fluids and tissues, the sensitive
microphone in the transducer records tiny
changes in the sound's pitch and direction.
• These signature waves are instantly measured
and displayed by a computer, which in turn
creates a real-time picture on the monitor.
• One or more frames of the moving pictures are
typically captured as still images.
• Small loops of the moving “real time” images may
also be saved.
• Doppler ultrasound, a special application of
ultrasound, measures the direction and speed of
blood cells as they move through vessels.
• The movement of blood cells causes a change in
pitch of the reflected sound waves (called the
Doppler effect).
• A computer collects and processes the sounds
and creates graphs or color pictures that
represent the flow of blood through the blood
vessels.
 Piezoelectric crystal (silver cube)
 How it Works
How is the procedure
performed?• For most ultrasound exams, the patient is positioned
lying face-up on an examination table that can be
tilted or moved.
• A clear water-based gel is applied to the area of the
body being studied to help the transducer make
secure contact with the body and eliminate air
pockets between the transducer and the skin that can
block the sound waves from passing into your body.
• The sonographer (ultrasound technologist) or
radiologist then presses the transducer firmly against
the skin in various locations, sweeping over the area of
interest or angling the sound beam from a farther
location to better see an area of concern.
• Doppler sonography is performed using the same
transducer.
• When the examination is complete, the patient may be
asked to dress and wait while the ultrasound images are
reviewed.
• In some ultrasound studies, the transducer is attached to
a probe and inserted into a natural opening in the body.
These exams include:
• Transesophageal echocardiogram. The transducer is
inserted into the esophagus to obtain images of the
heart.
•Transrectal ultrasound. The transducer is inserted into a
man's rectum to view the prostate.
•Transvaginal ultrasound. The transducer is inserted into
a woman's vagina to view the uterus and ovaries.
•Most ultrasound examinations are completed within 30
minutes to an hour.
What are the benefits vs. risks?
Benefits
•Most ultrasound scanning is noninvasive (no needles or
injections) and is usually painless.
•Ultrasound is widely available, easy-to-use and less
expensive than other imaging methods.
•Ultrasound imaging does not use any ionizing radiation.
•Ultrasound scanning gives a clear picture of soft tissues that
do not show up well on x-ray images.
•Ultrasound is the preferred imaging modality for the
diagnosis and monitoring of pregnant women and their
unborn babies.
•Ultrasound provides real-time imaging, making it a good tool
for guiding minimally invasive procedures such as needle
biopsies and needle aspiration.
Risks
•For standard diagnostic ultrasound there are no known
harmful effects on humans.
Future of Ultrasound
• Improved clarity for use in cancer diagnosis
• Increased therapeutic use to correct blood clots and kidney stones
• Portability and veterinary use
• Joint and muscle treatment through cavitation
• Fusion
• ShearWave Elastography
• 4D
Limitations of General Ultrasound Imaging?
• Ultrasound waves are disrupted by air or gas; therefore
ultrasound is not an ideal imaging technique for air-filled
bowel or organs obscured by the bowel. In most cases,
barium exams, CT scanning, and MRI are the methods of
choice in this setting.
• Large patients are more difficult to image by ultrasound
because greater amounts of tissue attenuates (weakens)
the sound waves as they pass deeper into the body.
• Ultrasound has difficulty penetrating bone and,
therefore, can only see the outer surface of bony
structures and not what lies within (except in infants).
For visualizing internal structure of bones or certain
joints, other imaging modalities such as MRI are
typically used.
Basics of Ultrasound

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Basics of Ultrasound

  • 2. Outline • What is Ultrasound imaging? • Why Ultrasound? • Common Uses • History • Properties of Ultrasound • Equipment • How does the procedure work? • Benefits and Risks
  • 3. What is General Ultrasound Imaging? • Ultrasound imaging, also called sonography, involves exposing part of the body to high- frequency sound waves to produce pictures of the inside of the body. • Ultrasound examinations do not use ionizing radiation (as used in x-rays). • Because ultrasound images are captured in real- time, they can show the structure and movement of the body's internal organs, as well as blood flowing through blood vessels.
  • 4. Why Ultrasound • Ultrasound (US) is the most widely used imaging technology worldwide • Popular due to availability, speed, low cost, patient-friendliness (no radiation) • Applied in obstetrics, cardiology, inner medicine, urology,... • Ongoing research to improve image quality, speed and new application areas such a intra- operative navigation, tumour therapy,...
  • 5. What are some common uses of the procedure? 1.Ultrasound examinations can help to diagnose a variety of conditions and to assess organ damage following illness. 2.Ultrasound is used to help physicians evaluate symptoms such as: •pain •swelling •infection •hematuria (blood in urine)
  • 6. Ultrasound is a useful way of examining many of the body's internal organs, including but not limited to the: • heart and blood vessels, including the abdominal aorta and its major branches • Liver • Gallbladder • Spleen • Pancreas • Kidneys • Bladder • Uterus, ovaries, and unborn child (fetus) in pregnant patients • Eyes • Thyroid and parathyroid glands • Scrotum (testicles) • brain in infants • hips in infants
  • 7. Ultrasound is also used to: •guide procedures such as needle biopsies, in which needles are used to extract sample cells from an abnormal area for laboratory testing. •image the breasts and to guide biopsy of breast cancer •diagnose a variety of heart conditions and to assess damage after a heart attack or diagnose for valvular heart disease.
  • 8. Doppler ultrasound images can help the physician to see and evaluate: • blockages to blood flow (such as clots). • narrowing of vessels (which may be caused by plaque). • tumors and congenital vascular malformation. With knowledge about the speed and volume of blood flow gained from a Doppler ultrasound image, the physician can often determine whether a patient is a good candidate for a procedure like angioplasty.
  • 9. Applications in Obstetrics • Follow fetal development • Detect pathologies Two-dimensional B-mode Ultrasound image of a fetus
  • 10. Defused liver with abscess General Radiology
  • 11. Carotid Artery with Color Doppler
  • 12. Three-dimensional image of the same fetus ~ 5 months after conception
  • 13. Applications in Cardiology •Blood flow in vessels (Doppler US) •Contraction, Rhythm •Blood flow in the heart (defects on wall muscle, valve defects •Assessment of cardiac perfusion sti
  • 14. Applications in Inner Medicine •Gallstone •Perfusion of renal transplant Gallstone (red arrow) within the gallbladder produces a bright surface echo and causes a dark acoustic shadow (S)
  • 15. Perfusion Doppler image of a renal transplant
  • 16. Applications in Musculoskeletal System • Visualisation of tendons, ligaments • Investigations under movement is possible – simplifies the detection of ruptures, obstructions… The arrows show the large gap of the rupture Achilles tendon
  • 17. US image of ISS astronaut Mike Fincke's biceps tendon, where "D" denotes the deltoid muscle and "T" is the proximal intracapsular end of the long biceps tendon
  • 18. Applications of Ultrasound Elastography US Elastography is often used to classify tumours. Malignant tumours are 10 to 100 times stiffer than the normal soft tissue around
  • 19. History The bat use Ultrasound for navigation
  • 20. History • 1877: Lord Raleigh - "Theory of Sound" • 1880: Pierre & Jacques Curie - Piezoelectric effect • 1914: Langevin - First Ultrasound generator using piezoelectric effect • 1928: Solokov - Ultrasound for material testing
  • 21. • 1942: Dussik - First application of Ultrasound in medical diagnostics • Shortly after WWII, researchers in Japan began to explore medical diagnostic capabilities of ultrasound. • ... different medical applications (gall stones, tumours) • End of 1960's: Boom of Ultrasound in medical diagnostics
  • 22. Pan-Scanner - The transducer rotated in a semicircular arc around the patient (1957)
  • 23. Scan converter allowed for the first time to use the upcoming computer technology to improve US
  • 24. • Early 1970s – Gray scale static images of internal organs •Mid 1970s – Real-time imaging •Early 1980s – Spectral Doppler – Color Doppler •Also produced was a hand-held “contact” scanner for clinical use.
  • 26. Development of the B-mode Ultrasound image quality
  • 27. Properties of Ultrasound The frequencies of medical Ultrasound waves are several magnitudes higher than the upper limit of → human hearing. Approximate frequency ranges of sound
  • 28. • Although ultrasound is better known for its diagnostic capabilities, it was initially used for therapy rather than diagnosis. • In the 1940s, ultrasound was used to perform services similar to that of radiation or chemotherapy now. • Ultrasonic waves emit heat that can create disruptive effects on animal tissue and destroy malignant tissue.
  • 29. Common Sound Frequencies Sound Frequency Adult audible range 15 – 20’000 Hz Range for children's hearing Up to 40’000 Hz Male speaking voice 100 – 1’500 Hz Female speaking voice 150 ‘ 2’500 Hz Standard pitch (Concert A) 44 0 Hz Bat 50’000 – 200’000 Hz Medical Ultrasound 2.5 – 40 MHz Maximum sound frequency 600 MHz Common sound frequencies and frequency ranges
  • 30. Physics of the method • Longitudinal mechanical waves • Needs elastic medium – Transducer needs to be in contact with skin • Wave velocity – Fat -> 1450 m/s – Muscle ->1580 m/s
  • 31. Principles of Ultrasound Its Components Operations Applications
  • 33. The Ultrasound Machine A basic ultrasound machine has the following parts: 1.Transducer probe - probe that sends and receives the sound waves 2.Central processing unit (CPU) - computer that does all of the calculations and contains the electrical power supplies for itself and the transducer probe 3.Transducer pulse controls - changes the amplitude, frequency and duration of the pulses emitted from the transducer probe 4.Display - displays the image from the ultrasound data processed by the CPU 5.Keyboard/cursor - inputs data and takes measurements from the display 6.Disk storage device (hard, floppy, CD) - stores the acquired images 7.Printer - prints the image from the displayed data
  • 34. Equipment • Ultrasound scanners consist of a console containing a computer and electronics, a video display screen and a transducer that is used to do the scanning. • The transducer is a small hand-held device that resembles a microphone, attached to the scanner by a cord. • The transducer sends out inaudible high frequency sound waves into the body and then listens for the returning echoes from the tissues in the body. • The principles are similar to sonar used by boats and submarines.
  • 35. • The ultrasound image is immediately visible on a video display screen that looks like a computer or television monitor. • The image is created based on the amplitude (strength), frequency and time it takes for the sound signal to return from the area of the patient being examined to the transducer and the type of body structure the sound travels through.
  • 36. • Types of Transducer
  • 37. How does the procedure work? • Ultrasound imaging is based on the same principles involved in the sonar used by bats, ships, fishermen and the weather service. • When a sound wave strikes an object, it bounces back, or echoes. • By measuring these echo waves, it is possible to determine how far away the object is and its size, shape and consistency (whether the object is solid, filled with fluid, or both). • In medicine, ultrasound is used to detect changes in appearance of organs, tissues, and vessels or detect abnormal masses, such as tumors.
  • 38. • In an ultrasound examination, a transducer both sends the sound waves and receives/records the echoing waves. • When the transducer is pressed against the skin, it directs small pulses of inaudible, high- frequency sound waves into the body. • As the sound waves bounce off of internal organs, fluids and tissues, the sensitive microphone in the transducer records tiny changes in the sound's pitch and direction.
  • 39. • These signature waves are instantly measured and displayed by a computer, which in turn creates a real-time picture on the monitor. • One or more frames of the moving pictures are typically captured as still images. • Small loops of the moving “real time” images may also be saved. • Doppler ultrasound, a special application of ultrasound, measures the direction and speed of blood cells as they move through vessels. • The movement of blood cells causes a change in pitch of the reflected sound waves (called the Doppler effect). • A computer collects and processes the sounds and creates graphs or color pictures that represent the flow of blood through the blood vessels.
  • 42. How is the procedure performed?• For most ultrasound exams, the patient is positioned lying face-up on an examination table that can be tilted or moved. • A clear water-based gel is applied to the area of the body being studied to help the transducer make secure contact with the body and eliminate air pockets between the transducer and the skin that can block the sound waves from passing into your body. • The sonographer (ultrasound technologist) or radiologist then presses the transducer firmly against the skin in various locations, sweeping over the area of interest or angling the sound beam from a farther location to better see an area of concern.
  • 43. • Doppler sonography is performed using the same transducer. • When the examination is complete, the patient may be asked to dress and wait while the ultrasound images are reviewed. • In some ultrasound studies, the transducer is attached to a probe and inserted into a natural opening in the body. These exams include: • Transesophageal echocardiogram. The transducer is inserted into the esophagus to obtain images of the heart. •Transrectal ultrasound. The transducer is inserted into a man's rectum to view the prostate. •Transvaginal ultrasound. The transducer is inserted into a woman's vagina to view the uterus and ovaries. •Most ultrasound examinations are completed within 30 minutes to an hour.
  • 44. What are the benefits vs. risks? Benefits •Most ultrasound scanning is noninvasive (no needles or injections) and is usually painless. •Ultrasound is widely available, easy-to-use and less expensive than other imaging methods. •Ultrasound imaging does not use any ionizing radiation. •Ultrasound scanning gives a clear picture of soft tissues that do not show up well on x-ray images. •Ultrasound is the preferred imaging modality for the diagnosis and monitoring of pregnant women and their unborn babies. •Ultrasound provides real-time imaging, making it a good tool for guiding minimally invasive procedures such as needle biopsies and needle aspiration. Risks •For standard diagnostic ultrasound there are no known harmful effects on humans.
  • 45. Future of Ultrasound • Improved clarity for use in cancer diagnosis • Increased therapeutic use to correct blood clots and kidney stones • Portability and veterinary use • Joint and muscle treatment through cavitation • Fusion • ShearWave Elastography • 4D
  • 46. Limitations of General Ultrasound Imaging? • Ultrasound waves are disrupted by air or gas; therefore ultrasound is not an ideal imaging technique for air-filled bowel or organs obscured by the bowel. In most cases, barium exams, CT scanning, and MRI are the methods of choice in this setting. • Large patients are more difficult to image by ultrasound because greater amounts of tissue attenuates (weakens) the sound waves as they pass deeper into the body. • Ultrasound has difficulty penetrating bone and, therefore, can only see the outer surface of bony structures and not what lies within (except in infants). For visualizing internal structure of bones or certain joints, other imaging modalities such as MRI are typically used.