This industrial visit report summarizes a visit by pharmacy students to The Madras Pharma facility in Chennai, India. The report provides details of the company's manufacturing capabilities and departments visited including production, quality control, and packaging. It notes that students observed manufacturing processes, had questions answered by company personnel, and gained practical knowledge to strengthen their theoretical classroom learning. The visit provided valuable career insights and real-world application of pharmaceutical concepts taught in class.
1. A REPORT OF PROJECT
On
"INDUSTRIAL VISIT REPORT"
at
Shri Venkateshwara College of Pharmacy
SUBMITTED IN PARTIAL FULFILLMENT OF THE
REQUIREMENT FOR THE AWARDOF THE DEGREE OF
BACHELOR OF PHARMACY
JULY, 2022
SUBMITTED TO: SUBMITTED BY:
MRS.E.NIRMALA RAJA KARTHIKEYAN
ASSOCIATE PROFESSOR 19180267
VICE PRINCIPAL BPHARM 3RDYEAR
SVCP SVCP
2. CONTENT
Topic
Abstract
Acknowledgement
About the The Madras Pharma
MADRAS PHARMA
Company Profile
Plant
DOSAGE FORM &
CAPACITY
Capsules
Tablets
Liquids
Creams/Ointments
EXPERTISE
Manufacturing
R&D
Quality
MACHINAERY
FINAL REPORT
Letter on industrial visit
Conclusion
Reference
3. ABSTRACT
Industrial training is an important phase of a student life. A well planned, properly executed
and evaluated industrial training helps a lot in developing a professional attitude. It develop
an awareness of industrial approach to problem solving, based on a broad understanding of
process and mode of operation of organization. The aim and motivation of this industrial
training is to receive discipline, skills, teamwork and technical knowledge through a proper
training environment, which will help me, as a student in the field of Information Technology,
to develop a responsiveness of the self-disciplinary nature of problems in information and
communication technology. Throughout this industrial training, I have been learned new
techniques of packaging, quality control etc related to capsules.
4. ACKNOWLEDGEMENT
I have taken efforts in this project. However, it would have been possible without the kind
support and help of many individuals. It is indeed a great pleasure to work on this project and
presenting this report to my department. This project had provided me a good exposure to the
real world problem and also a solution to that.
I would like to pay my heartiest thanks to Dr. Duraivel, Dean of SVCP & Mrs.E.Nirmala.
Vice Principal, Department of Pharmaceutics, SVCP who provided me such a wonderful
opportunity to pursue my mini project on such an interesting topics. My heartfelt
thanks go to all other faculties who provided valuable suggestions and kind co-operation. I
would like to thanks our placement officer Mr. Anandaraj, for importing his valuable
guidance and support. He has not only provided suggestions but also rectified my problems
whenever I have faced any problems.
I would like to express my special gratitude and thanks to persons who rendered their assistance
directly or indirectly. I would like to express my gratitude towards my parents & friends for
their kind co-operation and encouragement which help me in this project.
Raja Karthikeyan
Bachelor of Pharma,
SVCP
5. The Madras Pharmaceuticals
Company Profile
Started in the year 1979, The Madras Pharma group is a contract manufacturing
organization, having 8 manufacturing facilities, 3000 employees, covering all
dosage forms and selling products in India and across the world.
The Madras Pharmaceuticals is one of the most respected contract research and
manufacturing (CRAMS) organization in India. We are a B2B business that out
licenses the generic products that are developed by our in-house R&D to the
pharmaceutical marketing companies against a supply agreement. We do not
own any brands in India and we are a pure play CRAMS partner thereby not
competing with our customers in the market.
Key Facts :
7 manufacturing Sites.
Capability to manufacture all dosage forms and all therapeutic categories.
3000+ employees.
1 million + Sqft of operational space.
INR 500 crore + turnover.
2/3rds of the business comes from India and the remaining 1/3rd from
overseas markets.
2 of the facilities (Softgel and Sterilgene) are EU-GMP approved and are
going for the USFDA in 2019.
History
5 healthcare professionals from Madurai Medical College got together to start
the Madras Pharmaceuticals in the year 1979 with a very small seed capital. In
the initial days the company operated out of a rented space of around 2000 sqft.
The company made a profit even in the first year of inception and from then on
it bootstrapped to build 7 manufacturing facilities spread across India. Over the
years the promoters either acquired existing business to turn them around or
built manufacturing facilities to cater to the growing demands.
6. Our Values
we develop and manufacture products with the Patient in the mind,
ensuring we deliver the safest and most innovative products that has the
highest performance with a continuous supply.
We use the latest technologies and innovations to be Excellent in
whatever we do.
We ensure that our People are engaged, motivated, grow professionally
and personally.
We offer the highest Customer satisfaction.
Integrity is our core strength, We demonstrate accountability, honesty,
sustainability, ethics and respect in our every action.
7. The Madras Pharma
PLANT
The Madras Pharmaceuticals
Our flagship facility started its operations in 1979 in Chennai, India with an
employee count of 10 with production capacity of 1M tablets a month to an
employee count of 500 with production capacity of 300M tablets, 50M
capsules, 150KL liquids and 0.75 tons ointments.
Madras Pharmaceuticals caters to the top clients in domestic and ROW market
like Pfizer, Abbott, Cipla, Lupin, Sun Pharma, USV, etc. With a turnover of
around USD27M per annum Madras Pharmaceuticals is one of the leading
contract manufacturing facilities in India.
8. Manufacturing
Manufacturing
Madras Pharma is one of the most promising contract manufacturing
organization in the Indian Pharma Industry that serves the pharmaceutical
industry with comprehensive services from drug development to manufacturing.
We have 7 state-of-art manufacturing facilities producing formulations in
almost all dosage forms and therapeutic segments for most of the leading
Pharma companies across the globe.
Working with a CMO helps our business partners save upfront capital
investment for drug development, thus minimizing the overall project costs and
helps them focus their resource in their core competency – Brand development
& recognition.
Madras Pharma does not limit its activities to CMO but has set in the trend of
Contract Research and Manufacturing Services (CRAMS) in Indian Pharma
industry. Madras Pharma takes the projects for the development of new
products; file applications with Directorate Controller General of India (DCGI)
and upon approval offer the products to the clients in its own technology.
Madras Pharma also arranges Bio-equivalence studies and Clinical trials
whenever required.
Madras Pharma has seven state-of-the-art world class manufacturing facilities
equipped with ultramodern plants and machineries for manufacturing
formulations in wide range of dosage forms, including; tablets, hard & soft
gelatin capsules, dry & liquid syrups, dry & liquid injectable, nutraceuticals,
dermatological & hormonal products.
Madras Pharma has centralized big walk-in stability chambers for accessing
stability of the products in different packing under different temperature and
humidity conditions as per the requirement of different zones.
Madras Pharma has appointed well Experienced Qualified and Competent
Technical Personnel in various departments like Quality Assurance, Quality
Control, Production, Personnel & Administration, Engineering & Warehouse
and more.
9. R&D
Madras Pharma is a technology driven company supported by extensive
Formulation Development and Analytical Development departments; coupled
with well-equipped laboratories and best talented technical officials of the
industry. Madras Pharma has plant wise R&D (Both formulation and analytical)
departments equipped with best of facilities.
Great emphasis is laid on continuous improvement in process, quality and
development of new products.
Our laboratory is fully equipped for physical, chemical testing along with
micro-biological testing. Madras Pharma has centralized R&D Unit for all the
dosage forms comprising of crème de la crème in the pharma industry.
At the R&D center not only the focus is on new product development but we
also work on making the existing ones better.
About the R&D centre
Madras Pharma group has state-of-the-art research centre for
development of generic finished dosage forms. R&D is well equipped to
handle various developmental challenges in the areas of oral and
parenteral medications for both regulated and Emerging markets.The
Centre is capable of developing, scaling up and commercializing various
dosage forms like tablets, capsules, soft gels and injectable’s drug
delivery systems.
The formulation team is supported well by an analytical team that can
develop complex in-vitro analytical methods for various molecules
including extremely potent drug combinations to support formulation
development team.
A team of 70+ Scientists with various specializations are dedicated to
development of Formulation and Analytical research. The team is
supported by dedicated Project Management Team to drive R&D
projects.
10. Our strength and Capabilities
Our RnD team has vast experience in Modified Release, Novel Drug
Delivery System (NDDS), Multiple Particulate system (MUPS) and
Parenteral Injections and Lyophilized powders and has a deep working
knowledge in Formulation development, Manufacturing and
Commercialization of Oral solids, Soft gel and Parentrals.
Dedicated Tech Transferteam with 10+ associates, with graduate and post
graduate in pharmacy, having experience in Technology transfer and
scale up operations to manufacture the products.
Our Formulation Development Laboratory has been geared up for a state-
of-the-art R & D facility in line with the US-FDA, UK-MHRA, EU
requirements. The laboratory is well equipped with various ultramodern
equipments and technologies required for conducting high quality
research activities and prototype equipments as that of manufacturing
facilities.
The Formulation R & D Capability includes
o Design and development of new dosage forms
o Pre formulation studies
o Lab / pilot scale studies
o Process optimization/validation studies
o Stability studies as per ICH guidance
o Technology transfer of new products
o Technical supports to manufacturing location
o Technology and latest development upgradation to provide
technically superior, process efficient and International standards
product.
Analytical Development capabilities include
o Development & validation of various analytical test procedures for
Assay
o Content Uniformity, Dissolution, Related Substances, Residual
Solvents, other in-house test procedures
o Finalization of Specifications which will adequately evaluate desire
quality attributes.
Expertised in different type of therapeutic related development like
Hormonal disorders, steroids, Potent drugs, NSAID’s and other general
category drugs.
The Plant is equipped with R&D lab scale equiments to different level of
scale up sizes required for developing and commercializing in house and
customer projects.
Products are developed to satisfy customer needs and the attribute of
product health impact is taken in to account as product-related factors in
the development process.
11. Quality
Madras Pharma aims to provide quality medicines that help people lead
healthier lives. The company shares passion for quality that goes way beyond
business and statutory requirements. Madras Pharma has unmatchable standards
and manufacture best quality products, satisfying norms for all multinationals &
big pharmaceutical houses of the country and qualifying International and
National Audits.
Our working standards are based on the principle that the key to stay ahead in
competition is ‘Quality’. The company believes that the product will rule the
market only when it conforms to the quality requirement of the customer – first
time and every time, meeting world-class standards.
Giving utmost importance to Quality, Madras Pharma has developed well
atomization in system and procedure throughout the organization to minimize
the risk & to produce world-class quality products. With the help of competent
and qualified technical team, the organization is dedicated to deliver quality
product.
Madras Pharma’s commitment to implementing a robust, global quality
management system is based upon the desire to sustain a culture of operational
excellence. Meeting and exceeding stakeholders’ expectations, including
marketing companies, patients and Government regulators are the guiding
pillars to company’s progression.
Madras Pharma employs the best of industry’s technical officials in its QC,
QA, ‘Production & Product’ Development Department. Their continuous
proactive efforts on the present .
Future needs of market are dedicated to meeting the customer requirements
through consistent development of Technology, Quality, drug delivery
systems, Packaging and more.
It is towards this end that the company believes in Total Quality Management.
The organization’s commitment to regulatory excellence supports the objective
of providing safe and efficacious pharmaceutical products to the customers
worldwide.
12. MACHINERY
MACHINERY CAPACITY MAKE
Granulation – 5
Sections
120 Kgs
M/s.ACE ,M/s .Anchor Mark,
M/s.Alliance Engineering
&Ms.Yanchen
Compressions 12 Nos. M/s.Cadmach and M/s.Parle
Auto Coating – 4 Nos 150 Kgs
M/s.Sejong Coating ,M/s.Neo
Machines
Automatic Hard Gel
Capsulation – 3 (Size :
00 to 4)
40000 to 90000
capsules per hour
fill
M/s.ACG PharmaParma
Manual Hard Gel
Capsulation M/C-3
NA
M/s.ACG Pharm Parma and
M/s.Anchor Mark
Dry Powder Filling 60 BPM M/s.Anchor Mark
Bulk Counting 60 BPM M/.Parle
Packing – 5 Lines -
Blister,Alu Alu,Strip
Alu PVC & Alu
PVDC
NA
M/s.ACG Pharm Parma ,
M/s.Elmac , M/s.Vilac
Enginerring &M/s.Ganson
Liquid –
Manufacturing 2
Lines
5000 Ltr and 3000
Ltr
M/s.Bectochem
Liquid-Bottle
Washing and Filling –
2 Lines
180 BPM & 120
BPM
M/s.Anchor Mark
Liquid-Pouch Packing
line
60 PPM M/s.Wraptech
Semisolid line-
Manufacturing and
Filling- 3 Lines
150
Kgs,400Kgs,1500
Kgs
Ms.Anchor
Mark,M/s.Betochemand
M/s.Pro Pack
Ointment Filling and
Packing – 2 Line
120 TPM
M/s.WIMCO and M/s.Square
Pharma
Regulatory
Regulatory
13. REPORT ON INDUSTRIAL VISIT
DATE: 07/082022
SUBJECT:
Report on industrial visit of 2022 took place in Chennai on 23th
July 2022.
RESPECTED SIR/MADAM,
On receiving the letter of permission from “THE MADRAS PHARMA”
80 students along with the faculty members went on the industrial visit to the
factory on 23/07/2022. We assembled at the college at 06:00am and left the
college in the tourist bus. We reached the factory at 10:00am. It was 2-3hrs
journey and students are advised to wear formal dress along with the shoes of
any kind.
A production-in-charge gave us brief introduction about the factory. Inside the
industries students only carried notepads and pen to take notes whatever you
see inside the industries. The company would not allow any bags, mobile
phones or other electronics inside the industries and strict checking was been
done once you enter the company premises. They gave us mask to be worn.
The workers was seen doing the work concentrated. Everybody was seen
wearing the surgical masks.
Inside the industry the students were given a tour of various departments viz.
Production unit, Quality control unit. Etc. While entering into the production
unit, the students were advised to wear aprons, disposable head masks and
shoe caps so that the contamination would stay minimal. Before entering to
these unit high speed air is passed so that the dust from the clothes get
removed.
14. After the visit in various departments there would have been a discussion
session where all the queries of the students were answered by the higher
personals of the industry. It was truly an exciting and enlightening visit for all
the students.
We left the premises at 03:00pm. It was informative, interesting and successful
visit. As a students of pharmacy, we learnt about the processing of drugs. We
express our thanks to the DEAN sir who permitted us to go on the visit, the
faculty members accompanied us and officials who explained various
departments. On behalf of students I request you to arrange more industrial
visit for the students which can practically train the students.
THANKING YOU
YOURS FAITHFULLY,
RAJAKARTHIKEYAN U
19180267
B.PHARM 3RD
YEAR
15. CONLUSION
The primary goal of this report is to visiting this company gives a practical
exposure to current work practices to strengthen theoretical knowledge being
taught at college.
During this visit we had visited Formulation and Production section, Quality
Control and Packaging section where all the faculty are valued equality and
treated with respect.
THE MADRAS PHARMA helped us to imbibe the detailed information about
tablet section & packaging section.
This industrial training provided a valuable learning experience in the carrier
exploration
process and gave us unexpected benefit. Now I have evaluated the class room
taught facts and ideas and applied them to the real-life situation. We came to
know about many things such as the GMP (Good Manufacturing Process), the
Current Good Manufacturing Process (CGMP). The basic laboratory
requirement for product validation, the variety of machine used in the large-
scale industries of medicine etc.
These and many other factors cause the enhance of my knowledge and have
created a lifelong interest to learning through an exposure to new educational
experience.
Moreover, the various large-scale pharma manufacturing equipment and
its applications were also keenly observed by us. Thus it turned out to be a
great experience, full of new and advanced learning regarding industry.
