2. Cardiac Arrest
Cardiac arrest is the cessation of all cardiac
mechanical activity. It’s clinical diagnosis is
confirmed by
Unresponsiveness
Absence of detectable pulse
Apnea (or agonal respirations )
3. The Cardiac Arrest Rhythms
The four cardiac arrest rhythms are
Asystole
PEA ( Pulseless Electrical Activity )
Pulseless Ventricular Tachcardia (VT)
Ventricular Fibrillation (VF)
4. International Guidelines for CPR 2005
International consensus on the art
& science of CPR
Based on the most extensive
evidence review of CPR
Recommendations designed to
improve survival from sudden
cardiac arrest (SCA)
Circulation Volume 112, Issue 24
Supplement; December 13, 2005
5. AHA Class of Recommendation
Class I
Definitely recommended
Class II a
Acceptable and useful
Class II b
Acceptable and useful
Indeterminate
Promising, evidence
lacking, immature
Class III
May be harmful: no
benefit documented
excellent evidence
good to very good evidence
fair to good evidence
no harm and no benefit
not acceptable, not useful,
may be harmful
6. Chain Of Survival – 4 links
BLS
Call for help
Early Defibrillation
Early CPR
Early Advanced
Care
21. D – Early Defibrillation
Automated External Defibrillator (AED)
Single greatest advance in CPR
The survival rate is 90% if
the patient is defibrillated
within 1 min. and only 10%
if it is delayed till 10mins
(Circulation 1984;69:943-8.)
Survival rate after cardiac
arrest has been reported to
go up from 30% to 49%
(Ann Emerg Med 1996;28:480-5.)
22. Biphasic vs Monophasic Defibrillation
Advantages
- greater efficacy
- low energy produces same effect
- less myocardial damage
- less incidence of S-T changes
( Ital Heart J Suppl. 2002 Jun;3(6):638-45 )
Energy
- Monophasic 360 J
- Biphasic 150/200 J
All AEDs are Biphasic
High first shock success of
Biphasic defibrillation (84%-95%)
23. BLS Algorithm ( Primary ABCD )
Step 1. Assess Responsiveness
Step 2. Activate the EMS and call for the defibrillator
Step 3. Open the airway
Step 4. Assess Breathing (“ look, listen and feel ” )
Step 5. If Breathing is absent, give two slow rescue breaths
Step 6. Check for pulse (carotid pulsations)
Step 7. If pulse is absent initiate “ Chest Compressions ”
As soon as a defibrillator is available attach and
defibrillate if indicated
25. A - Airway
Definitive airway should be secured as soon as possible
Tracheal intubation using cricoid pressure (by trained
personnel only)
Laryngeal Mask Airway (LMA) and Esophageal–tracheal
Combitube are accepted alternatives for others
Cricothyrotomy to be performed in an emergency
26. B. Breathing - Confirm device placement
Primary Confirmation
Direct Visualisation of ETT passing through cords
Chest expansion
5 point auscultation
- L and R anterior,
- L and R mid-axillary
- Over stomach
Still in doubt –repeat laryngoscopy
Further confirmation
- Exhaled CO2 detector (ETCO2)
- Oesophageal detector device
Inflate cuff and secure the tube
27. B. Breathing –
Confirm effective oxygenation and ventilation
No synchrony between ventilation and chest
compressions once definitive airway is secured
No longer 30 : 2 compression ventilation cycles
COMPRESSION @100/min
VENTILATION @ 6 – 8 breaths/min
28. C. Circulation
Identify the rhythm
Defibrillation /Pacing
Secure IV line-large easily accessible peripheral veins
Give rhythm appropriate medication
29. Recognition of Rhythm
Cardiac Arrest (lethal rhythms)
Shockable-VF,Pulseless VT
Non Shockable – Asystole.PEA
Non Cardiac Arrest (non lethal rhythm)
Rate too fast - >120/min
Rate too slow- <60/min
30. Defibrillation
For shockable rhythms – VF / Pulseless VT
Monophasic or Biphasic defibrillators (Biphasic preferred)
Monophasic 360 J ~ Biphasic 200 J
Steps of Defibrillation
- Mains plugged in or on battery, On Defib mode
- ECG size/gain maximum
- Set on leads: Only set on paddles if no leads
- Select joules (200,300 & all others 360)
- Charge, (“all clear”chant to count of 3 before discharge)
- Discharge
31. Pacing
Disappointing results for asystole, PEA
No benefit in post shock asystole
May be indicated for cardiac arrest with
narrow QRS complexes
Not useful during terminal wide complex
agonal rhythms
Extensive use in pre-arrest bradyarrhythmias
Transcutaneous or transvenous
32. C-Circulation
IV Access
Wide bore peripheral upper limb vein
Push each bolus with 20cc fluid
Raise extremity
Urgent central/femoral line only if peripheral
access impossible or difficult & taking a long time
to cannulate
33. C-Circulation
Other Drug Delivery Routes
Tracheal
- 2-3 times IV dose
- Dilute in 10 ml saline
- Preferably inject down a suction catheter which
is wedged deep into the bronchus
- Rapid bagging
Intracardiac route
- Not recommended
- Dangerous
can result in refractory VF or convert to
nonshockable rhythm
34. C - Circulation
Rhythm appropriate medications
Epinephrine
Indicated in all cardiac arrest rhythms
i.e. VF, Pulse less VT, Asystole and PEA
IV dose is 1mg administered every 3-5 minutes
followed by 20 ml IV saline flush
Adrenaline causes intense cardio-cerebral sparing
vasoconstriction CPR generates CO 25% of normal
Beneficial effects outweigh negative effects on the myocardium
35. Vasopressin
Antidiuretic hormone and a powerful vasoconstrictor
when used in the higher doses.
Positive effects of epinephrine with lesser adverse
effects . Effect lasts for 20 minutes
Dose - 40 IU
Drug of choice for all 4 rhythms
Pulseless VT , VF, Asystole and PEA
One dose of vasopressin may replace either the first
or the second dose of epinephrine
36. Atropine
First drug of choice in symptomatic bradycardia (class I )
Second drug after epinephrine for asystole and
bradycardic PEA ( class II b ).
Dose is 1mg IV push, repeat every 3-5 minutes up to a
maximum dose of 0.04 mg /kg .
37. Amiodarone
Persistent or recurrent VF or VT ( class II b )
Dose is 300 mg IV push (150 mg may be repeated after
3-5 minutes ) may be followed by a 24 hour infusion of
1mg / minute for 6 hours and then 0.5 mg/minute for the
remaining 18 hours.
Amiodarone preferred over Lignocaine (class
indeterminate ) in the treatment of persistent or
recurrent VF /VT.
38. Sodium Bicarbonate
Specific indications are as follows
class I
if known pre-existing hyperkalemia
class II a if known bicarbonate responsive acidosis TCA overdose
class II b after prolonged resuscitation with
effective ventilation
class III hypercarbic acidosis
The dose is 1 meq/kg bolus, repeat half this dose every
10 minutes thereafter
39. Calcium
Detrimental effect on ischaemic myocardium
Impairs cerebral recovery
NOT TO BE USED ROUTINELY
Indicated in PEA due to
Hyperkalaemia
Hypocalcaemia
Ca channel blocker overdose
40. Magnesium sulphate
Shock
refractory ventricular fibrillation in
pr of possible hypomagnesemia
Torsades de pointes
VT in pr of possible hypomagnesemia
Dose : 1 –2 g (4-8 mmol ) MgSO4 over 1-2
min,can be repeated after 10 –15 min
41. D. Differential Diagnosis
Review the most frequent causes
( the 5 H’s and 5 T’s )
Hypovolemia
Tablets ( Toxins)
Hypoxia
Tamponade - cardiac
Hydrogen ions – acidosis
Tension pneumothorax
Hyper / hypokalemia
Thrombosis - coronary
Hypothermia
Thrombosis - pulmonary
42. ACLS - Secondary ABCD
Survey
A Airway :
place airway device as soon as possible
B Breathing :
confirm airway device placement
by examination plus confirmation device
secure airway device
confirm effective oxygenation & ventilation
B Breathing :
B Breathing :
C
C
C
C
Circulation :
Circulation :
Circulation :
Circulation :
identify rhythm – monitor
Defibrillation/Pacing
establish IV access
give medications appropriate for rhythm and
condition
D Differential Diagnosis : search for and treat identified reversible
causes
43. Monitoring the Victim -
To assess effectiveness of rescue efforts
Monitor for signs of circulation and breathing
Check pulse during compression to assess
effectiveness of compression
To determine ROSC after 2 minutes of chest
compression check for pulse
ETCO2