This document provides an overview of prosthetic devices. It discusses the different types of prostheses including upper and lower extremity prostheses. The major types described are trans-humeral, trans-radial, trans-femoral, and trans-tibial prostheses. The document also outlines the typical components of a prosthesis including the socket, suspension, control system, and terminal device. Common materials used in prosthetics like metal, polymer, carbon fiber, and supporting materials are mentioned. Finally, the document discusses the different categories of upper limb prosthetic systems including passive, body powered, externally powered myoelectric, hybrid, and activity-specific prostheses.
Prosthesis upper limb and lower limb.pptxBadalverma11
Physiotherapy- Complete details about prosthesis both upper and lower limb, and training and physiotherapy management #gait training #sports
Contents-
Introduction
Purpose
Components
Upper limb- above elbow And below elbow, socket, cable mechanism, elbow and wrist unit, hand/terminal device
Lower limb- above knee, below knee and syme prosthesis
Socket- quadrilateral, PTB
Knee and ankle unit
Foot
Physiotherapy management -
First therapy, muscle strengthening, mobility
Training of don and doff , care of. Stump and bandaging
Gait training and sports
@cpu
The document discusses different types of prostheses for various body parts including craniofacial, intra-oral, extra-oral, limb, and somato prostheses. It provides details on specific prostheses such as transradial, transfemoral, transtibial and transhumeral prostheses. The summary discusses costs, options for body-powered versus electric prostheses, and types of terminal devices including hooks, prehensors, and hands.
1. Upper limb amputations occur frequently due to trauma, tumors, and diseases. Prosthetic options include body-powered, myoelectric, and hybrid prostheses.
2. Myoelectric prostheses provide more grip force but rely on electromyography signals from muscles. Body-powered prostheses are durable but restrictive.
3. Advances in prosthetics include improved suspension through suction sockets, microprocessor control of wrist/elbow function, and water-resistant terminal devices.
1. Upper limb amputations occur frequently due to trauma, tumors, and diseases. Prosthetic options include body-powered, myoelectric, and hybrid prostheses.
2. Myoelectric prostheses provide more grip strength and functional range compared to body-powered prostheses but require targeted muscle sites and electrodes.
3. Advances in prosthetic interfaces, microprocessor technology, waterproof components, and speed have improved the function and real-world use of electronic upper limb prostheses.
This document discusses rehabilitation and prosthetics for upper extremity amputees. It covers:
1. Exercises that should be started after amputation to improve range of motion, strength, and endurance, and avoid contractures.
2. Techniques for performing daily activities like bathing and dressing without a prosthesis by changing hand dominance or using the mouth/feet.
3. The main components of prosthetics including the socket, harness, mechanical elbow, and different terminal devices.
4. Advances in prosthetics technology including myoelectric hands, targeted muscle reinnervation, and future considerations like osseointegration.
Prosthetic management of individuals with upper extremity
amputations presents all health professionals, including
prosthetists and therapists, with a set of unique challenges.
For those wearing an upper extremity prosthesis, the terminal
device (TD) of the prosthesis is not covered or obscured
by clothing in the same way that a lower extremity prosthesis
is “hidden” by pants, socks, and shoes. The person with
upper extremity amputation must cope with not only physical
appearance changes, but the loss of some of the most
complex movement patterns and functional activities of
the human body.
In addition, upper extremity limb loss deprives the patient
of an extensive and valuable system of tactile and proprioceptive
inputs that previously provided “feedback” to guide and
refine functional movement. Even the simplest tasks
related to grasp and release become challenging. The ability
to position the prosthetic limb segments in space, as well as
the ability to maintain advantageous postures needed to
manipulate objects, challenge the medical community to
continuously improve the functional and aesthetic outcomes
of prostheses for patients in this population.
1. A prosthesis is a device that replaces a missing body part and can support existing limbs.
2. There are two main types of prostheses - body-powered which use cables for control, and externally powered which use electric motors.
3. Prostheses aim to restore appearance and function as much as possible. Terminal devices like hooks aim to replicate different grips.
A prosthesis is an artificial replacement for any part of the body that is missing. It is designed to replace the function and appearance of the missing limb as much as possible. Prostheses for lower and upper limb amputations are prescribed based on the level and cause of amputation. The main components of a prosthesis are the socket, suspension system, control system, and terminal device. The socket provides an intimate fit with the residual limb. Suspension systems like belts and harnesses help hold the prosthesis securely. Control systems can be body-powered using cables or externally powered using batteries. Terminal devices replace missing hands or feet. The goal is to restore ambulation and functional tasks using a prosthesis.
Prosthesis upper limb and lower limb.pptxBadalverma11
Physiotherapy- Complete details about prosthesis both upper and lower limb, and training and physiotherapy management #gait training #sports
Contents-
Introduction
Purpose
Components
Upper limb- above elbow And below elbow, socket, cable mechanism, elbow and wrist unit, hand/terminal device
Lower limb- above knee, below knee and syme prosthesis
Socket- quadrilateral, PTB
Knee and ankle unit
Foot
Physiotherapy management -
First therapy, muscle strengthening, mobility
Training of don and doff , care of. Stump and bandaging
Gait training and sports
@cpu
The document discusses different types of prostheses for various body parts including craniofacial, intra-oral, extra-oral, limb, and somato prostheses. It provides details on specific prostheses such as transradial, transfemoral, transtibial and transhumeral prostheses. The summary discusses costs, options for body-powered versus electric prostheses, and types of terminal devices including hooks, prehensors, and hands.
1. Upper limb amputations occur frequently due to trauma, tumors, and diseases. Prosthetic options include body-powered, myoelectric, and hybrid prostheses.
2. Myoelectric prostheses provide more grip force but rely on electromyography signals from muscles. Body-powered prostheses are durable but restrictive.
3. Advances in prosthetics include improved suspension through suction sockets, microprocessor control of wrist/elbow function, and water-resistant terminal devices.
1. Upper limb amputations occur frequently due to trauma, tumors, and diseases. Prosthetic options include body-powered, myoelectric, and hybrid prostheses.
2. Myoelectric prostheses provide more grip strength and functional range compared to body-powered prostheses but require targeted muscle sites and electrodes.
3. Advances in prosthetic interfaces, microprocessor technology, waterproof components, and speed have improved the function and real-world use of electronic upper limb prostheses.
This document discusses rehabilitation and prosthetics for upper extremity amputees. It covers:
1. Exercises that should be started after amputation to improve range of motion, strength, and endurance, and avoid contractures.
2. Techniques for performing daily activities like bathing and dressing without a prosthesis by changing hand dominance or using the mouth/feet.
3. The main components of prosthetics including the socket, harness, mechanical elbow, and different terminal devices.
4. Advances in prosthetics technology including myoelectric hands, targeted muscle reinnervation, and future considerations like osseointegration.
Prosthetic management of individuals with upper extremity
amputations presents all health professionals, including
prosthetists and therapists, with a set of unique challenges.
For those wearing an upper extremity prosthesis, the terminal
device (TD) of the prosthesis is not covered or obscured
by clothing in the same way that a lower extremity prosthesis
is “hidden” by pants, socks, and shoes. The person with
upper extremity amputation must cope with not only physical
appearance changes, but the loss of some of the most
complex movement patterns and functional activities of
the human body.
In addition, upper extremity limb loss deprives the patient
of an extensive and valuable system of tactile and proprioceptive
inputs that previously provided “feedback” to guide and
refine functional movement. Even the simplest tasks
related to grasp and release become challenging. The ability
to position the prosthetic limb segments in space, as well as
the ability to maintain advantageous postures needed to
manipulate objects, challenge the medical community to
continuously improve the functional and aesthetic outcomes
of prostheses for patients in this population.
1. A prosthesis is a device that replaces a missing body part and can support existing limbs.
2. There are two main types of prostheses - body-powered which use cables for control, and externally powered which use electric motors.
3. Prostheses aim to restore appearance and function as much as possible. Terminal devices like hooks aim to replicate different grips.
A prosthesis is an artificial replacement for any part of the body that is missing. It is designed to replace the function and appearance of the missing limb as much as possible. Prostheses for lower and upper limb amputations are prescribed based on the level and cause of amputation. The main components of a prosthesis are the socket, suspension system, control system, and terminal device. The socket provides an intimate fit with the residual limb. Suspension systems like belts and harnesses help hold the prosthesis securely. Control systems can be body-powered using cables or externally powered using batteries. Terminal devices replace missing hands or feet. The goal is to restore ambulation and functional tasks using a prosthesis.
UPPER EXTREMITY ROBOTICS EXOSKELETON: APPLICATION, STRUCTURE AND ACTUATIONijbesjournal
Robotic exoskeleton is getting important to human in many aspects such as power assist, muscle training, regain motor function and rehabilitation. The research and development towards these functions are expected to be combined and integrated with the human intelligent and machine power, eventually becoming another generation of robot which will enhance the machine intelligent and human power. This paper reviews the upper extremity exoskeleton with different functions, actuators and degree of freedom (DOF). Among the functions, rehabilitation and power assist have been highlighted while pneumatic actuator, pneumatic muscle, motor and hydraulic actuator are presented under the categories of actuator. In addition, the structure of exoskeleton is separated by its DOF in terms of shoulder, elbow, wrist and hand.
UPPER EXTREMITY ROBOTICS EXOSKELETON: APPLICATION, STRUCTURE AND ACTUATIONijbesjournal
Robotic exoskeleton is getting important to human in many aspects such as power assist, muscle training, regain motor function and rehabilitation. The research and development towards these functions are expected to be combined and integrated with the human intelligent and machine power, eventually becoming another generation of robot which will enhance the machine intelligent and human power. This paper reviews the upper extremity exoskeleton with different functions, actuators and degree of freedom (DOF). Among the functions, rehabilitation and power assist have been highlighted while pneumatic actuator, pneumatic muscle, motor and hydraulic actuator are presented under the categories of actuator. In addition, the structure of exoskeleton is separated by its DOF in terms of shoulder, elbow, wrist and hand
This document discusses the development of a low-cost prosthetic hand for people who have lost the use of their arm. It aims to design a hand that can perform basic grasping and holding functions through the sensing of muscle activity in the forearm. The system would use low-cost materials and motors to open and close soft prosthetic fingers similar to an umbrella opening and closing. This would provide an affordable alternative to existing high-cost prosthetics that use complex brain-signal control. The document reviews different types of existing prosthetic hands and the mechanics, electronics, and safety aspects considered in the design project.
The document discusses upper limb prosthetics, including different levels of amputation, types of prostheses, components, socket designs, suspension systems, and terminal devices. It defines various amputation levels from transphalangeal to forequarter and describes prosthetic options for each level. The major components of upper limb prostheses are the socket, suspension, control system, and terminal device. Socket designs vary depending on the amputation level and suspension type. Suspension systems include harness, self-suspending socket, suction, and semi-suction options. Terminal devices can be either passive cosmetic hands or active hooks and hands controlled by cable or battery.
This document discusses upper limb prosthetics. It describes the characteristics of a successful prosthesis, considerations when choosing a prosthesis, reasons for upper limb amputations, amputation levels, types of prosthetics including cosmetic, functional, body-powered, externally powered and myoelectric prosthetics. It provides details on the typical components of an upper limb body-powered prosthesis including the socket, suspension, control cables, terminal devices and any intervening joint components. It outlines the timelines for amputation and prosthetic fitting.
This document provides an overview of prosthetics and orthotics. It defines prosthetics as the replacement of missing body parts and orthotics as devices that support, align, or correct deformities of movable body parts. The document describes various types of prosthetics and orthotics for the upper and lower limbs, including components, materials, and designs. It also discusses indications and functions for different orthotic devices used in the cervical, thoracic, and lumbar spine regions.
NET 2014-Myoelectric Prosthetic Hand with Air musclesRosemary James T
This document describes the development of a myoelectric prosthetic hand that uses pneumatic-controlled tendon-driven air muscles to increase power-to-weight ratio. Surface EMG electrodes acquire signals from residual muscles which are processed by a microcontroller to control pneumatic valves and actuate air muscles. The air muscles are coupled to tendons connected to a three-fingered prosthetic hand through a spring-loaded system. Testing showed the prosthetic hand could flex to 85 degrees and extend to 110 degrees, with each PSI of pressure providing 3mm of extension. The prosthetic design aims to improve functionality through a simpler actuation mechanism compared to electric motors.
This document summarizes research on artificial intelligence arms and prosthetic hands. It discusses how prosthetic limbs have advanced with developments in information technology, allowing them to more easily connect to a person's brain or muscles for movement. However, current prosthetic hands remain inferior to natural hands. The document also reviews the history of prosthetic hand development from pneumatic to myoelectric systems. Despite advances, rejection rates of upper limb prosthetics remain high. Future improvements may come from advances in areas like materials, battery life, control systems, surgical techniques, and 3D printing.
NET Paper no 63-Myoelectric Prosthetic Hand with Air musclesRosemary James T
This document describes the development of an EMG-activated, tendon-driven myoelectric prosthetic hand that uses air muscles for actuation. The hand aims to provide high power-to-weight ratio and efficiency by mimicking human muscle motion. EMG signals from residual limb muscles are conditioned and used to control pneumatic valves that regulate air pressure in artificial muscles. These air muscles act as tendons to flex prosthetic finger joints via spring-loaded mechanisms. The design improves on motor-driven hands by reducing complexity while maintaining functionality.
Raphadon provides a range of prosthetic, orthotic, and medical tourism services including artificial limbs, braces, diabetic foot care, and cosmetic prosthetics, and is owned by experienced specialists; it focuses on helping people live normal lives through the latest technologies and works with major brands worldwide to import high-quality products.
This document presents a research proposal for designing and fabricating a lightweight and comfortable prosthetic arm. The objectives are to develop an adaptable grip mechanism, create an affordable prosthetic arm with optimal degrees of freedom, integrate feedback systems, innovate socket design, and explore alternative mechanisms. A literature review found that existing prosthetics have predefined grips, high costs, weight issues, and lack feedback. The methodology will develop the design, fabricate a prototype, and test it. The significance is that it could enhance prosthetic accessibility and functionality to positively impact users' lives.
The slide is about the prosthetic devices. how they are design and implemented along with the relation with the biomechanics. We have also discuss about the scenario in context of nepal.
>Prepared by the Biomedical Engineering Student Nepal
Abstract: This paper gives about an idea about the issues concerning the integration of artificial limbs. This paper includes on overview of research finding on the development of BIONIC ARMS that are used as prosthetic arms. Controlling by the sensory feedback system. The system are used on vibration and electrical system and combination of the two methods.
Upper Limb Prosthetics - Dr Om Prakashmrinal joshi
This document provides information on upper limb prostheses. It discusses the history of prosthetics, levels of amputation, types of prosthetic systems (passive, body-powered, externally powered, hybrid), components (socket, suspension, control mechanisms, terminal devices), and considerations for prosthetic selection and use. The key points are that upper limb loss can be devastating, prosthetics can replace some hand functions but not sensation, and the appropriate prosthesis depends on the amputation level, expected use, and individual factors.
This document provides an overview of prosthesis body parts. It discusses the history of prosthetics from ancient times to modern technologies. It covers the types of prosthetics including upper and lower extremity prosthetics, dental prosthetics, myoelectric prosthetics, hip prosthetics, and knee prosthetics. It also discusses the materials, manufacturing process, advantages and disadvantages of prosthetics.
This document discusses prosthetic body parts. It begins with an introduction to prosthetics and their history. It then covers the various applications and advantages of prosthetics, as well as some disadvantages. The document outlines the different types of raw materials and prosthetics, including upper and lower extremity prosthetics, dental prosthetics, myoelectric prosthetics, hip prosthetics, and knee prosthetics. It concludes with sections on the technology and manufacturing of prosthetics, and performance criteria.
Bionic arm is a revolutionary idea for amputees across the globe. This is as close as we can get to our natural limb. The fundamental point is to make the arm move with our brain unlike previous prosthetic upper limbs
The document discusses bionics, which combines biology and electronics. It describes how bionic devices can replace organs like ears, arms, and eyes. Examples provided include a bionic arm that can rotate 360 degrees and artificial muscles made of materials that contract and expand like human muscles in response to electricity. The document also discusses developments in bionic eyes like an implantable artificial retina and bionic ears. It concludes by questioning whether future generations will be led by humans, robots, or bionic humans.
UPPER EXTREMITY ROBOTICS EXOSKELETON: APPLICATION, STRUCTURE AND ACTUATIONijbesjournal
Robotic exoskeleton is getting important to human in many aspects such as power assist, muscle training, regain motor function and rehabilitation. The research and development towards these functions are expected to be combined and integrated with the human intelligent and machine power, eventually becoming another generation of robot which will enhance the machine intelligent and human power. This paper reviews the upper extremity exoskeleton with different functions, actuators and degree of freedom (DOF). Among the functions, rehabilitation and power assist have been highlighted while pneumatic actuator, pneumatic muscle, motor and hydraulic actuator are presented under the categories of actuator. In addition, the structure of exoskeleton is separated by its DOF in terms of shoulder, elbow, wrist and hand.
UPPER EXTREMITY ROBOTICS EXOSKELETON: APPLICATION, STRUCTURE AND ACTUATIONijbesjournal
Robotic exoskeleton is getting important to human in many aspects such as power assist, muscle training, regain motor function and rehabilitation. The research and development towards these functions are expected to be combined and integrated with the human intelligent and machine power, eventually becoming another generation of robot which will enhance the machine intelligent and human power. This paper reviews the upper extremity exoskeleton with different functions, actuators and degree of freedom (DOF). Among the functions, rehabilitation and power assist have been highlighted while pneumatic actuator, pneumatic muscle, motor and hydraulic actuator are presented under the categories of actuator. In addition, the structure of exoskeleton is separated by its DOF in terms of shoulder, elbow, wrist and hand
This document discusses the development of a low-cost prosthetic hand for people who have lost the use of their arm. It aims to design a hand that can perform basic grasping and holding functions through the sensing of muscle activity in the forearm. The system would use low-cost materials and motors to open and close soft prosthetic fingers similar to an umbrella opening and closing. This would provide an affordable alternative to existing high-cost prosthetics that use complex brain-signal control. The document reviews different types of existing prosthetic hands and the mechanics, electronics, and safety aspects considered in the design project.
The document discusses upper limb prosthetics, including different levels of amputation, types of prostheses, components, socket designs, suspension systems, and terminal devices. It defines various amputation levels from transphalangeal to forequarter and describes prosthetic options for each level. The major components of upper limb prostheses are the socket, suspension, control system, and terminal device. Socket designs vary depending on the amputation level and suspension type. Suspension systems include harness, self-suspending socket, suction, and semi-suction options. Terminal devices can be either passive cosmetic hands or active hooks and hands controlled by cable or battery.
This document discusses upper limb prosthetics. It describes the characteristics of a successful prosthesis, considerations when choosing a prosthesis, reasons for upper limb amputations, amputation levels, types of prosthetics including cosmetic, functional, body-powered, externally powered and myoelectric prosthetics. It provides details on the typical components of an upper limb body-powered prosthesis including the socket, suspension, control cables, terminal devices and any intervening joint components. It outlines the timelines for amputation and prosthetic fitting.
This document provides an overview of prosthetics and orthotics. It defines prosthetics as the replacement of missing body parts and orthotics as devices that support, align, or correct deformities of movable body parts. The document describes various types of prosthetics and orthotics for the upper and lower limbs, including components, materials, and designs. It also discusses indications and functions for different orthotic devices used in the cervical, thoracic, and lumbar spine regions.
NET 2014-Myoelectric Prosthetic Hand with Air musclesRosemary James T
This document describes the development of a myoelectric prosthetic hand that uses pneumatic-controlled tendon-driven air muscles to increase power-to-weight ratio. Surface EMG electrodes acquire signals from residual muscles which are processed by a microcontroller to control pneumatic valves and actuate air muscles. The air muscles are coupled to tendons connected to a three-fingered prosthetic hand through a spring-loaded system. Testing showed the prosthetic hand could flex to 85 degrees and extend to 110 degrees, with each PSI of pressure providing 3mm of extension. The prosthetic design aims to improve functionality through a simpler actuation mechanism compared to electric motors.
This document summarizes research on artificial intelligence arms and prosthetic hands. It discusses how prosthetic limbs have advanced with developments in information technology, allowing them to more easily connect to a person's brain or muscles for movement. However, current prosthetic hands remain inferior to natural hands. The document also reviews the history of prosthetic hand development from pneumatic to myoelectric systems. Despite advances, rejection rates of upper limb prosthetics remain high. Future improvements may come from advances in areas like materials, battery life, control systems, surgical techniques, and 3D printing.
NET Paper no 63-Myoelectric Prosthetic Hand with Air musclesRosemary James T
This document describes the development of an EMG-activated, tendon-driven myoelectric prosthetic hand that uses air muscles for actuation. The hand aims to provide high power-to-weight ratio and efficiency by mimicking human muscle motion. EMG signals from residual limb muscles are conditioned and used to control pneumatic valves that regulate air pressure in artificial muscles. These air muscles act as tendons to flex prosthetic finger joints via spring-loaded mechanisms. The design improves on motor-driven hands by reducing complexity while maintaining functionality.
Raphadon provides a range of prosthetic, orthotic, and medical tourism services including artificial limbs, braces, diabetic foot care, and cosmetic prosthetics, and is owned by experienced specialists; it focuses on helping people live normal lives through the latest technologies and works with major brands worldwide to import high-quality products.
This document presents a research proposal for designing and fabricating a lightweight and comfortable prosthetic arm. The objectives are to develop an adaptable grip mechanism, create an affordable prosthetic arm with optimal degrees of freedom, integrate feedback systems, innovate socket design, and explore alternative mechanisms. A literature review found that existing prosthetics have predefined grips, high costs, weight issues, and lack feedback. The methodology will develop the design, fabricate a prototype, and test it. The significance is that it could enhance prosthetic accessibility and functionality to positively impact users' lives.
The slide is about the prosthetic devices. how they are design and implemented along with the relation with the biomechanics. We have also discuss about the scenario in context of nepal.
>Prepared by the Biomedical Engineering Student Nepal
Abstract: This paper gives about an idea about the issues concerning the integration of artificial limbs. This paper includes on overview of research finding on the development of BIONIC ARMS that are used as prosthetic arms. Controlling by the sensory feedback system. The system are used on vibration and electrical system and combination of the two methods.
Upper Limb Prosthetics - Dr Om Prakashmrinal joshi
This document provides information on upper limb prostheses. It discusses the history of prosthetics, levels of amputation, types of prosthetic systems (passive, body-powered, externally powered, hybrid), components (socket, suspension, control mechanisms, terminal devices), and considerations for prosthetic selection and use. The key points are that upper limb loss can be devastating, prosthetics can replace some hand functions but not sensation, and the appropriate prosthesis depends on the amputation level, expected use, and individual factors.
This document provides an overview of prosthesis body parts. It discusses the history of prosthetics from ancient times to modern technologies. It covers the types of prosthetics including upper and lower extremity prosthetics, dental prosthetics, myoelectric prosthetics, hip prosthetics, and knee prosthetics. It also discusses the materials, manufacturing process, advantages and disadvantages of prosthetics.
This document discusses prosthetic body parts. It begins with an introduction to prosthetics and their history. It then covers the various applications and advantages of prosthetics, as well as some disadvantages. The document outlines the different types of raw materials and prosthetics, including upper and lower extremity prosthetics, dental prosthetics, myoelectric prosthetics, hip prosthetics, and knee prosthetics. It concludes with sections on the technology and manufacturing of prosthetics, and performance criteria.
Bionic arm is a revolutionary idea for amputees across the globe. This is as close as we can get to our natural limb. The fundamental point is to make the arm move with our brain unlike previous prosthetic upper limbs
The document discusses bionics, which combines biology and electronics. It describes how bionic devices can replace organs like ears, arms, and eyes. Examples provided include a bionic arm that can rotate 360 degrees and artificial muscles made of materials that contract and expand like human muscles in response to electricity. The document also discusses developments in bionic eyes like an implantable artificial retina and bionic ears. It concludes by questioning whether future generations will be led by humans, robots, or bionic humans.
Ähnlich wie Limb Prosthetic ,types of limb Prosthetic (20)
Travel vaccination in Manchester offers comprehensive immunization services for individuals planning international trips. Expert healthcare providers administer vaccines tailored to your destination, ensuring you stay protected against various diseases. Conveniently located clinics and flexible appointment options make it easy to get the necessary shots before your journey. Stay healthy and travel with confidence by getting vaccinated in Manchester. Visit us: www.nxhealthcare.co.uk
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
Summer is a time for fun in the sun, but the heat and humidity can also wreak havoc on your skin. From itchy rashes to unwanted pigmentation, several skin conditions become more prevalent during these warmer months.
Debunking Nutrition Myths: Separating Fact from Fiction"AlexandraDiaz101
In a world overflowing with diet trends and conflicting nutrition advice, it’s easy to get lost in misinformation. This article cuts through the noise to debunk common nutrition myths that may be sabotaging your health goals. From the truth about carbohydrates and fats to the real effects of sugar and artificial sweeteners, we break down what science actually says. Equip yourself with knowledge to make informed decisions about your diet, and learn how to navigate the complexities of modern nutrition with confidence. Say goodbye to food confusion and hello to a healthier you!
Know the difference between Endodontics and Orthodontics.Gokuldas Hospital
Your smile is beautiful.
Let’s be honest. Maintaining that beautiful smile is not an easy task. It is more than brushing and flossing. Sometimes, you might encounter dental issues that need special dental care. These issues can range anywhere from misalignment of the jaw to pain in the root of teeth.
The Children are very vulnerable to get affected with respiratory disease.
In our country, the respiratory Disease conditions are consider as major cause for mortality and Morbidity in Child.
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7shruti jagirdar
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
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Discover the benefits of homeopathic medicine for irregular periods with our guide on 5 common remedies. Learn how these natural treatments can help regulate menstrual cycles and improve overall menstrual health.
Visit Us: https://drdeepikashomeopathy.com/service/irregular-periods-treatment/
4. Prosthetic devices
A prosthesis is a device designed to replace a missing part of the body
or to make a part of the body work better.
A prosthesis is an artificial replacement for any or all parts of the
lower or upper extremities .
It is device that designed to replace , as much as possible , the
function or appearance of a missing limb or body part.
Image from pinterest.com
4
6. Types of prostheses
Trans-Humeral
it is an artificial limb that replaces an arm that missing above
the elbow.
A trans-humeral prosthesis helps to replace the function of a
missing anatomical segment(s) from below the shoulder to
(and including) the hand.
Trans-humeral Prosthesis image from
indiamart.com
6
7. Types of Prosthesis
Trans-Radial
Replaces an arm missing below the elbow.
Cosmetic prosthesis: is for appearance only and does not move.
Body-powered prosthesis: is connected to the body by a series of
cables.
Myoelectric prosthesis: It connects an electronic hand to the muscles in
arm.
Trans-Radial Prosthesis From
northern-orthopedic-laboratory
7
8. Types of prosthesis
Trans-femoral Prosthesis
A trans-femoral prosthesis is an artificial limb that replaces
any amputated limb above the knee.
The prosthesis is made from a high-quality raw material
known as polypropylene.
It is an artificial limb that replaces a leg missing above the
knee.
Trans-Femoral Prosthesis Image
from ResearchGate
8
9. Types of prosthesis
Trans-tibial Prosthesis:
It is an artificial limb that replaces a leg missing below the
knee.
A trans-tibial prosthesis replaces the function of missing
anatomical segment(s) from below the knee to the floor. Trans-tibial Prosthesis image from
prosthetic-rehabclinic
9
11. Socket
The point at which the prosthesis is attached to the wearer’s
own body, these are cast to fit the person’s residual limb as
comfortably and securely as possible.
Today’s prosthetic sockets are made from modern plastic
and silicone materials as they offer a good mixture of
comfort and functionality for the patient.
Some of the first trans-femoral sockets were made from
wood and leather.
Socket image from Arm
Dynamics
11
12. Suspension
It is for attaching socket to the body.
Harness:
made of rigid or elastic belts.
Belt suspensions are not a stable solution but can act in
synergy with other suspension systems.
Subatmospheric : suspension , based on the
regulation of negative pressures values within the
socket.
12
14. Control system
Bionic limb: is controlled by the electric signals from the
muscle and/or nerves above the level of the amputation.
Bidirectional control: is then completed via sensation
restoration through the connection of the remaining nerves or
muscles above the level of amputation to the prosthetic device
sensors.
14
Image from mdpi.com
15. Fig : Block scheme of the PNS-based control of a prosthetic system
15
16. Terminal device
This refers to the prosthetic hand at the end of the prosthesis, which
can be a hook, claw, or device that more closely resembles a hand.
Passive TDs are used primarily for cosmetic.
Body-powered control allows for voluntary opening (VO) or
voluntary closing (VC) of the TD, but not both.
Externally powered TDs can have digital or proportional control
and can open or close as desired and offer the advantage of higher
grip force.
Image from researchgate.net
16
18. Material
18
Metals:
• A variety of metals are used for prosthetics limbs; Aluminium,
Titanium, Magnesium, Copper, Steel, and many more. They are each
used in a varied amount and for various applications, either pure or
alloyed.
• Copper, iron, aluminium and nickel have all been used for the load
bearing structure in the past, but are currently used primarily as alloys
.
• Titanium It has good strength to weight ratio, good strength to density
ratio, excellent corrosion resistance, low density and it is lightweight .
19. 19
Polymers:
Polymers are not often used for as the main load bearing structure for limbs. They are more common with
phalanges, joints, and other smaller body parts.
Common polymers used are poly-oxymethylene (POM), which is a hard polymer, pliable polyurethane (PU),
which is much softer, and poly vinyl chloride (PVC),which is used as a coating.
Carbon Fibers:
The properties of carbon fibers , such as high stiffness, high tensile strength, low weight, high chemical resistance ,
high temperature tolerance and low thermal expansion, high specific strength and specific modulus.
It was determined that it could be strong enough for even a heavy weight amputee.
Supporting Materials:
Supporting materials used in prosthetics are Spenco, Poron, Nylon-‐reinforced
silicone, Nickelplast.
20. Upper limb prosthesis
Five categories of
upper limb
prosthetic system
Passive prosthesis
Body powered
prosthesis
Externally powered
myoelectric
prosthesis
Hybrid prosthesis
Activity-specific
prosthesis
20
22. Passive prostheses
devices don’t offer active movement, they improve function by providing a surface for bracing and
carrying items.
Some designs include locking joints to allow for positioning the arm or bending the fingers to hold an
object.
Passive prostheses are often made from silicone for a natural, lifelike appearance, and can also be
created from lightweight metals and plastics that offer a high-tech look.
Assist In balance , stabilization of object(such as holding down paper when writing),and
recreational/vocational activities.
They look like a natural limb and are the lightest and cheapest, but they do not provide active hand and
joint movement.
22
23. Body powered prosthesis
They allow the prosthetic user to control the terminal device via a harness
system that fits around the chest and shoulder.
A strap-cable system holds the prosthesis on and uses the motion of the
person’s shoulder blade and upper arm to operate the hook , hand , and / or
elbow joint.
Some systems use the opposite arm to trigger one particular function; one end
of a strap encircles the opposite arm at the armpit, and the other end connects
to a cable that controls the terminal device (hook, hand, or specialty device for
particular function).
23
24. Externally powered myoelectric prosthesis
Externally powered prostheses use a battery powered electric motor to control
the terminal device, eliminating the need of a harness system.
Sensors, embedded in the socket, pick up an EMG signal on the skin and
transfer it to a processor which controls the functions of the motor.
Provide active hand and joint movement, without needing shoulder or body
motion.
Sensors and other inputs use muscle movement of the residual limb.
24
25. Hybrid prosthesis
Hybrid systems are a combination of externally and body powered prostheses.
Are typically used for higher level upper-limb amputation.
they combines specific features of body power and myoelectric power.
For example, a body-powered elbow might be combined with an externally
powered hand or terminal device.
25
26. Activity specific prostheses
Are for people who participate in activities that could damage the residual limb or
everyday prosthesis , or when the everyday prosthesis would not function
effectively.
These prostheses often include a specially design interface, socket, suspension
system, and terminal device.
Activity-specific terminal devices can allow the person to grasp a hammer and
other tools, a golf club, or baseball bat, or hold a baseball glove.
26
27. Adewuyi, A. A., Hargrove, L. J., and Kuiken, T. A. (2016). Evaluating EMG feature and classifier selection for
application to partial-hand prosthesis control. Front. Neurorobotics 10:15. doi: 10.3389/fnbot.2016.00015.
Agnew, W. F., McCreery, D. B., Yuen, T. G., and Bullara, L. A. (1989). Histologic and physiologic evaluation
of electrically stimulated peripheral nerve: considerations for the selection of parameters. Ann. Biomed. Eng.
17,39–60. doi: 10.1007/BF02364272.
Antfolk, C., Bjorkman, A., Frank, S. O., Sebelius, F., Lundborg, G., and Rosen, B. (2012). Sensory feedback
from a prosthetic hand based on air-mediated pressure from the hand to the forearm skin. J. Rehabil. Med. 44,
702–707.doi: 10.2340/16501977-1001
Antfolk, C., D’Alonzo, M., Controzzi, M., Lundborg, G., Rosen, B., Sebelius, F., et al. (2013a). Artificial
redirection of sensation from prosthetic fingers to the phantom hand map on transradial amputees: vibrotactile
versus mechanotactile sensory feedback. IEEE Trans. Neural Syst. Rehabil. Eng. 21,112–120. doi:
10.1109/TNSRE.2012.2217989
Adewuyi, A. A., Hargrove, L. J., and Kuiken, T. A. (2016). Evaluating EMG feature and classifier selection for
application to partial-hand prosthesis control. Front. Neurorobotics 10:15. doi: 10.3389/fnbot.2016.00015
Agnew, W. F., McCreery, D. B., Yuen, T. G., and Bullara, L. A. (1989). Histologic and physiologic evaluation
of electrically stimulated peripheral nerve: considerations for the selection of parameters. Ann. Biomed. Eng.
17, 39–60. doi: 10.1007/BF02364272
References
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