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MODULE 6 - PROTEIN &
    EXERCISE
PROTEINS
Amino acids linked by peptide chains for
 proteins



The body requires 20 different amino acids

•   alanine, arginine, asparagine aspartic acid, cysteine, glutamine, glutamic
    acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, prol
    ine, serine, threonine, tryptophan, tyrosine, valine
Complete vs Incomplete Proteins

Complete - Contain the essential amino acids in the right ratio to
  maintain nitrogen balance and allow tissue growth & repair.


Incomplete - Lacks one or more essential amino acid
Roles of Protein
1. Protein in nervous and connective tissues do not participate in
   energy metabolism


2. Amino acid alanine Plays a key role in providing CHO fuel via
   gluconeogenesis during prolonged exercise


3. During strenuous exercise of long duration, alanine - glucose
   cycle accounts for 40 - 50% of liver's glucose release.
PROTEIN UTILIZATION
 •   Protein utilization depends on how well the total energy
     expenditure is met by the intake of food


 •   Inadequate total energy intake forces the athlete to burn
     protein


 •   This depletes muscle protein which is not desirable


 •   Protein requirement is about 20% of total calorie intake OR
     1.2 to 1.7g/kg body weight
a) PROTEIN REQUIREMENT FOR
ENDURANCE AND RESISTANCE EXERCISE
Protein Requirement for Endurance
Exercise
Endurance training might need about 1.2 to 1.6 g x kg(-1) x day(-
  1) (approximately 1.5 times the current RDA)


Serious endurance athletes need protein above the normal adult
  RDA for:


•   maintenance
                         Of LEAN MUSCLE
•   growth
•   repair


•   optimum immune system function
Not providing sufficient
protein will lead to lethargy,
anaemia and will cancel
beneficial effects of
exercise.




 In fed individuals protein is meant to contribute 1-8% to
 the energy expended depending on the sex and the
 duration of the athletic competition.
•   Protein is used in prolonged, continuous, moderate to
    intense activity (endurance)
•   5-10% of the energy needs for endurance exercise (>90
    minutes) may come from protein.
•   Protein synthesis is suppressed during exercise and
    stimulated when physical activity ends.
•   Endurance exercise appears to improve the efficiency of the
    body to utilize nitrogen.
•   Amino acids are used to repair muscle trauma that results
    from repeated muscle contractions and eccentric
    contractions in particular.
Activity:
Protein Requirement for Strength Exercise

Those involved in strength training might need to consume as
  much as 1.6 to 1.7 g protein x kg(-1) x day(-1) (approximately
  twice the current RDA)


Extra protein is needed by strength-trained athletes to repair
  injuries to muscle fibers and to remodel muscle tissue in
  response to strength training.
•   High intensity, intermittent activity that incorporates
    strength training in the exercise program.


•   Resistance exercise provides the stimulus for gains in muscle
    size and strength.


•   Strength training relies on anaerobic metabolism for energy
    production. The primary fuel for resistance exercise is muscle
    glycogen.


•   Building muscle is energy intensive.
b) PROTEIN TURNOVER IN EXERCISE
PROTEIN TURNOVER
•    Protein turnover (synthesis and degradation) is elevated in
     strength athletes.


•    Protein requirements are increased to supply amino acids to
     maintain nitrogen balance and to support enhanced rates of
     protein synthesis.


•    Protein turnover depends on the following factors
1.   Exercise intensity
2.   Exercise duration
3.   Training state
4.   Energy consumed
5.   Gender
Exercise Intensity




Exercise intensity affects the protein turnover directly, based on the
example shown above.
Exercise Duration

During long duration of exercise there is more break down of protein
resulting in the increase of by products of amino acid oxidation.
... to put this in perspective



        For example, a person who cycles for 60 minutes
        in a glycogen depleted state might use as much
        as 2.4 times the amount of protein as those with
        high initial glycogen levels.
Training State:


 •   Protein turnover    with endurance exercise.


 •   Protein turnover   when there is sufficient energy from
     glycogen.
             Protein-sparing action of carbohydrate
When there is an adequate intake of carbohydrate, the body
  does not need to metabolize muscle protein for energy.
Ensuring the energy requirement is met by carbohydrate is vital
  to preserve the protein in the body
c) BCAA AND FATIGUE
BCAA AND FATIGUE
Branched chain amino acids - Leucine, isoleucine, valine


Serotonin plays a role in the central mechanisms of fatigue


Serotonin is produced from tryptophan


Tryptophan is usually found in the blood bound to albumin or as
   free tryptophan


The amount of free tryptophan that crosses the blood brain
  barrier depends on the concentration of BCAA.
Mechanism - BCAA and Fatigue
During long duration exercise fat is broken down to produce
  energy as a result of which fatty acids are formed.


These fatty acids bind to albumin thus reducing the number of
  albumin binding sites for tryptophan.


At the same time exercise leads to the breakdown of BCAA which
   causes an imbalance in the tryptophan:BCAA ratio.


An increase in this ratio causes the free tryptophan to cross the
  blood brain barrier and INCREASES the amount of SEROTONIN
  leading to FATIGUE
What does 100 grams of protein look like in food?
                   Food        Amount Protein (grams)

             Raisin bran cereal 2 cups       10

                 1% milk       2 cups        16

                  Bread        2 slices      5

              Chicken breast   1 large       19
                                piece

               Swiss cheese    1 ounce       8

                Lean steak        1          34

              Baked potatoes   1 med         5

                 Broccoli       1 cup        6

                Egg white         1          3.6
d) PROTEIN SUPPLEMENTATION
PROTEIN SUPPLEMENTATION
Many use protein supplements believing that they enhance
  performance by way of increasing the production of anabolic
  hormones.


Some research shows that there is no significant effect of amino
  acid supplements on the


1. Hormone secretion
2. Training response
3. Exercise performance
However, this is a debatable topic and pros and cons will be
   discussed.
Effect on Hormones
Whey Protein
Whey protein is the protein contained in whey, the watery portion of milk that
  separates from the curds when making cheese.



Whey protein is used for improving athletic performance, as a food supplement, as an
  alternative to milk for people with lactose intolerance, for replacing or
  supplementing milk-based infant formulas, and for reversing weight loss and
  increasing glutathione (GSH) in people with HIV disease.
                                     Contraindication:
 Uses:
                                     Whey taken in regulated
 In conjunction with strenght        quantities does not have any
 training whey improves:             known side effects.

 1. Lean muscle mass                 If taken in excess can lead to:
 2. Strength
 3. Muscle size                      1. Nausea
                                     2. cramps
                                     3. Fatigue
                                     4. Reduced appetite
Casein
Casein is the main protein in milk. It is the ingredient in milk that
   solidifies when milk curdles. When people drink
   milk, digestive juices break down the casein into protein
   pieces called casein peptides
                                  Side-effects:
 Benefits:
                                  1. Rashes
 1. Improved muscle Mass
                                  2. Bloating,
 2. Great Muscle retention
                                  3. Hives
 3. Greater fat loss
                                  4. Stomach aches
 4. Helps increase energy
                                  and cramps
 5. Improves stamina
                                  5. Gastro-intestinal
                                  discomfort
L- carnitine




                                CONS:
PROS:
                                Some research shows :
1. Acts as a vasodilator in
peripheral tissues              1. No ergogenic effect

2. May enhance regional blood   2. Does nto increase
flow & oxygen delivery          anabolic processes

3. Improves oxygen supply to    3. No improvement in
damaged tissue - May improve    performance
DOMS - delayed onset muscle
soreness                        4. No enhanced recovery
Creatine
Creatine Benefits:
                     Creatine Risks:

                     Not many risks have been
                     documented after creatine
                     supplementation.

                     Short term use in healthy
                     men has had no detrimental
                     effect on blood pressure and
                     renal function.

                     Individuals with poor kidney
                     function should refrain from
                     taking this supplement.
Activity:
Interpret the following graph with regards to Total Creatine.
Discussion
Your thoughts on the use of protein supplements

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Module 6 mcc sports nutrition credit course- protein and exercise

  • 1. MODULE 6 - PROTEIN & EXERCISE
  • 2. PROTEINS Amino acids linked by peptide chains for proteins The body requires 20 different amino acids • alanine, arginine, asparagine aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, prol ine, serine, threonine, tryptophan, tyrosine, valine
  • 3. Complete vs Incomplete Proteins Complete - Contain the essential amino acids in the right ratio to maintain nitrogen balance and allow tissue growth & repair. Incomplete - Lacks one or more essential amino acid
  • 4. Roles of Protein 1. Protein in nervous and connective tissues do not participate in energy metabolism 2. Amino acid alanine Plays a key role in providing CHO fuel via gluconeogenesis during prolonged exercise 3. During strenuous exercise of long duration, alanine - glucose cycle accounts for 40 - 50% of liver's glucose release.
  • 5. PROTEIN UTILIZATION • Protein utilization depends on how well the total energy expenditure is met by the intake of food • Inadequate total energy intake forces the athlete to burn protein • This depletes muscle protein which is not desirable • Protein requirement is about 20% of total calorie intake OR 1.2 to 1.7g/kg body weight
  • 6. a) PROTEIN REQUIREMENT FOR ENDURANCE AND RESISTANCE EXERCISE
  • 7. Protein Requirement for Endurance Exercise Endurance training might need about 1.2 to 1.6 g x kg(-1) x day(- 1) (approximately 1.5 times the current RDA) Serious endurance athletes need protein above the normal adult RDA for: • maintenance Of LEAN MUSCLE • growth • repair • optimum immune system function
  • 8. Not providing sufficient protein will lead to lethargy, anaemia and will cancel beneficial effects of exercise. In fed individuals protein is meant to contribute 1-8% to the energy expended depending on the sex and the duration of the athletic competition.
  • 9. Protein is used in prolonged, continuous, moderate to intense activity (endurance) • 5-10% of the energy needs for endurance exercise (>90 minutes) may come from protein. • Protein synthesis is suppressed during exercise and stimulated when physical activity ends. • Endurance exercise appears to improve the efficiency of the body to utilize nitrogen. • Amino acids are used to repair muscle trauma that results from repeated muscle contractions and eccentric contractions in particular.
  • 11.
  • 12. Protein Requirement for Strength Exercise Those involved in strength training might need to consume as much as 1.6 to 1.7 g protein x kg(-1) x day(-1) (approximately twice the current RDA) Extra protein is needed by strength-trained athletes to repair injuries to muscle fibers and to remodel muscle tissue in response to strength training.
  • 13. High intensity, intermittent activity that incorporates strength training in the exercise program. • Resistance exercise provides the stimulus for gains in muscle size and strength. • Strength training relies on anaerobic metabolism for energy production. The primary fuel for resistance exercise is muscle glycogen. • Building muscle is energy intensive.
  • 14. b) PROTEIN TURNOVER IN EXERCISE
  • 15. PROTEIN TURNOVER • Protein turnover (synthesis and degradation) is elevated in strength athletes. • Protein requirements are increased to supply amino acids to maintain nitrogen balance and to support enhanced rates of protein synthesis. • Protein turnover depends on the following factors 1. Exercise intensity 2. Exercise duration 3. Training state 4. Energy consumed 5. Gender
  • 16. Exercise Intensity Exercise intensity affects the protein turnover directly, based on the example shown above.
  • 17. Exercise Duration During long duration of exercise there is more break down of protein resulting in the increase of by products of amino acid oxidation.
  • 18. ... to put this in perspective For example, a person who cycles for 60 minutes in a glycogen depleted state might use as much as 2.4 times the amount of protein as those with high initial glycogen levels.
  • 19. Training State: • Protein turnover with endurance exercise. • Protein turnover when there is sufficient energy from glycogen. Protein-sparing action of carbohydrate When there is an adequate intake of carbohydrate, the body does not need to metabolize muscle protein for energy. Ensuring the energy requirement is met by carbohydrate is vital to preserve the protein in the body
  • 20. c) BCAA AND FATIGUE
  • 21. BCAA AND FATIGUE Branched chain amino acids - Leucine, isoleucine, valine Serotonin plays a role in the central mechanisms of fatigue Serotonin is produced from tryptophan Tryptophan is usually found in the blood bound to albumin or as free tryptophan The amount of free tryptophan that crosses the blood brain barrier depends on the concentration of BCAA.
  • 22. Mechanism - BCAA and Fatigue During long duration exercise fat is broken down to produce energy as a result of which fatty acids are formed. These fatty acids bind to albumin thus reducing the number of albumin binding sites for tryptophan. At the same time exercise leads to the breakdown of BCAA which causes an imbalance in the tryptophan:BCAA ratio. An increase in this ratio causes the free tryptophan to cross the blood brain barrier and INCREASES the amount of SEROTONIN leading to FATIGUE
  • 23. What does 100 grams of protein look like in food? Food Amount Protein (grams) Raisin bran cereal 2 cups 10 1% milk 2 cups 16 Bread 2 slices 5 Chicken breast 1 large 19 piece Swiss cheese 1 ounce 8 Lean steak 1 34 Baked potatoes 1 med 5 Broccoli 1 cup 6 Egg white 1 3.6
  • 25. PROTEIN SUPPLEMENTATION Many use protein supplements believing that they enhance performance by way of increasing the production of anabolic hormones. Some research shows that there is no significant effect of amino acid supplements on the 1. Hormone secretion 2. Training response 3. Exercise performance However, this is a debatable topic and pros and cons will be discussed.
  • 27. Whey Protein Whey protein is the protein contained in whey, the watery portion of milk that separates from the curds when making cheese. Whey protein is used for improving athletic performance, as a food supplement, as an alternative to milk for people with lactose intolerance, for replacing or supplementing milk-based infant formulas, and for reversing weight loss and increasing glutathione (GSH) in people with HIV disease. Contraindication: Uses: Whey taken in regulated In conjunction with strenght quantities does not have any training whey improves: known side effects. 1. Lean muscle mass If taken in excess can lead to: 2. Strength 3. Muscle size 1. Nausea 2. cramps 3. Fatigue 4. Reduced appetite
  • 28. Casein Casein is the main protein in milk. It is the ingredient in milk that solidifies when milk curdles. When people drink milk, digestive juices break down the casein into protein pieces called casein peptides Side-effects: Benefits: 1. Rashes 1. Improved muscle Mass 2. Bloating, 2. Great Muscle retention 3. Hives 3. Greater fat loss 4. Stomach aches 4. Helps increase energy and cramps 5. Improves stamina 5. Gastro-intestinal discomfort
  • 29. L- carnitine CONS: PROS: Some research shows : 1. Acts as a vasodilator in peripheral tissues 1. No ergogenic effect 2. May enhance regional blood 2. Does nto increase flow & oxygen delivery anabolic processes 3. Improves oxygen supply to 3. No improvement in damaged tissue - May improve performance DOMS - delayed onset muscle soreness 4. No enhanced recovery
  • 31. Creatine Benefits: Creatine Risks: Not many risks have been documented after creatine supplementation. Short term use in healthy men has had no detrimental effect on blood pressure and renal function. Individuals with poor kidney function should refrain from taking this supplement.
  • 32. Activity: Interpret the following graph with regards to Total Creatine.
  • 33. Discussion Your thoughts on the use of protein supplements