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1Cardiovascular Research Focus
www.ptglab.com
CARDIOVASCULAR
RESEARCH FOCUS
www.ptglab.com
Proteintech offers a wide range of markers
and related antibodies for cardiovascular research.
IF analysis of (4% PFA) fixed mouse heart tissue using TNNI3 antibody (21652-1-AP) at a dilution of 1:50.
2Cardiovascular Research Focus
www.ptglab.com
CONTENTS
Age-associated Changes
in Cardiovascular Tissues
mTOR in Cardiac Physiology
and Disease
Cardiac Troponin T Antibody
Cardio-related Antibodies
$99 Control Antibodies
Contact Us
3–4
5
6
7
8
9
3Cardiovascular Research Focus
www.ptglab.com
AGE-ASSOCIATED CHANGES
IN CARDIOVASCULAR TISSUES
Age-associated changes within the cardiovascular system contribute
to deregulation of molecular pathways and pathological alterations.
These include:
–– Hypertrophy
–– Altered left ventricular diastolic function
–– Abnormalities in arterial stiffness
–– Impaired endothelial function
4Cardiovascular Research Focus
www.ptglab.com
AGE-ASSOCIATED CHANGES
IN CARDIOVASCULAR TISSUES
Young Heart
Mature Heart
5Cardiovascular Research Focus
www.ptglab.com
mTOR IN CARDIAC PHYSIOLOGY & DISEASE
Inhibition of mTOR presents evidence for being cardioprotective
during aging and cardiac stress.
–– Antibody Name
	 mTOR
–– Catalog Number
	 20657-1-AP
Product Focus
Immunofluorescent analysis
of HeLa cells using mTOR
antibody (20657-1-AP)
at a dilution of 1:50 and
Alexa Fluor 488-conjugated
AffiniPure Goat Anti-Rabbit
IgG(H+L).
Immunohistochemistry of
paraffin-embedded human
testis using mTOR antibody
(20657-1-AP) at a dilution
of 1:50 (10x objective).
MCF7 cells were subjected
to SDS PAGE followed by
western blot with mTOR
antibody (20657-1-AP)
at a dilution of 1:500.
–– Type
	 Rabbit Polyclonal
–– Publications
	 19 publications
–– Applications
	 ELISA, IF, IHC,
	 IP, WB
6Cardiovascular Research Focus
www.ptglab.com
CARDIAC TROPONIN T ANTIBODY
cTnT is a cardiac regulatory protein involved in the control
of calcium-mediated interaction between actin and myosin.
–– Antibody Name
	 cTnT
–– Catalog Number
	 15513-1-AP
Immunofluorescent analysis
of (4% PFA) fixed mouse heart
tissue using cTnT antibody
(15513-1-AP) at a dilution
of 1:50 and Alexa Fluor
488-conjugated AffiniPure
Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of
paraffin-embedded human
heart using cTnT antibody
(15513-1-AP) at a dilution
of 1:50 (40x objective).
Mouse heart tissue was
subjected to SDS PAGE
followed by western blot with
cTnT antibody (15513-1-AP)
at a dilution of 1:1000.
–– Type
	 Rabbit Polyclonal
–– Publications
	 5 publications
–– Applications
	 ELISA, IF, IHC, WB
Product Focus
7Cardiovascular Research Focus
www.ptglab.com
CARDIO-RELATED ANTIBODIES
Antibody Name Catalog Number Applications Publications
ACTA2/smooth
muscle actin
14395-1-AP ELISA, FC, IF, IHC, IP, WB 57
CD31 (PECAM-1) 11265-1-AP ELISA, FC, IF, IHC, IP, WB 15
MYL7 17283-1-AP ELISA, IF, IHC, IP, WB 1
Myosin light chain 2 10906-1-AP ELISA, FC, IF, IHC, IP, WB 44
Immunohistochemistry of
paraffin-embedded human
heart tissue slide using ACTA2
antibody (14395-1-AP)
at a dilution of 1:5000
(40x objective).
Immunofluorescent analysis
of (-20ºC Ethanol) fixed
C2C12 cell using ACTA2
antibody (14395-1-AP)
at a dilution of 1:50.
Immunohistochemistry
of paraffin-embedded
human lung cancer using
PECAM1,CD31 antibody
(11265-1-AP) at a dilution
of 1:50 (10x objective).
Immunofluorescent analysis
of (4% PFA) fixed mouse
heart tissue using MYL2
antibody (10906-1-AP)
at a dilution of 1:50.
Immunofluorescent analysis
of (4% PFA) fixed mouse heart
tissue using MYL7 antibody
(17283-1-AP) at a dilution
of 1:50.
8Cardiovascular Research Focus
www.ptglab.com
$99 CONTROL
ANTIBODIES
Popular tag/control antibodies
are just $99 each.
GAPDH, beta Tubulin, and 6*His tag
antibodies included.
See the full list of tag/control antibodies at ptglab.com
PROMOTION
Corn whole-plant tissue
was subjected to SDS PAGE
followed by western blot
with GAPDH antibody
(60004-1-Ig) at a dilution
of 1:10000.
Immunofluorescent analysis
of HepG2 cells using beta-
Tubulin antibody (66240-1-
Ig) at a dilution of 1:50 and
Alexa Fluor 488-conjugated
AffiniPure Goat Anti-Mouse
IgG(H+L).
9Cardiovascular Research Focus
www.ptglab.com
CONTACT US
proteintech@ptglab.com
europe@ptglab.com
service@ptglab.com
Available 24 hours via Live Chat and 9–5
(CDT) via phone.
Proteintech Group
Proteintech Europe
Proteintech
Support
US Head Office
United Kingdom
China Office
Please visit us at www.ptglab.com for
more information about our antibodies
and technical tips.

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Cardiovascular Research Focus by Proteintech

  • 1. 1Cardiovascular Research Focus www.ptglab.com CARDIOVASCULAR RESEARCH FOCUS www.ptglab.com Proteintech offers a wide range of markers and related antibodies for cardiovascular research. IF analysis of (4% PFA) fixed mouse heart tissue using TNNI3 antibody (21652-1-AP) at a dilution of 1:50.
  • 2. 2Cardiovascular Research Focus www.ptglab.com CONTENTS Age-associated Changes in Cardiovascular Tissues mTOR in Cardiac Physiology and Disease Cardiac Troponin T Antibody Cardio-related Antibodies $99 Control Antibodies Contact Us 3–4 5 6 7 8 9
  • 3. 3Cardiovascular Research Focus www.ptglab.com AGE-ASSOCIATED CHANGES IN CARDIOVASCULAR TISSUES Age-associated changes within the cardiovascular system contribute to deregulation of molecular pathways and pathological alterations. These include: –– Hypertrophy –– Altered left ventricular diastolic function –– Abnormalities in arterial stiffness –– Impaired endothelial function
  • 4. 4Cardiovascular Research Focus www.ptglab.com AGE-ASSOCIATED CHANGES IN CARDIOVASCULAR TISSUES Young Heart Mature Heart
  • 5. 5Cardiovascular Research Focus www.ptglab.com mTOR IN CARDIAC PHYSIOLOGY & DISEASE Inhibition of mTOR presents evidence for being cardioprotective during aging and cardiac stress. –– Antibody Name mTOR –– Catalog Number 20657-1-AP Product Focus Immunofluorescent analysis of HeLa cells using mTOR antibody (20657-1-AP) at a dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Immunohistochemistry of paraffin-embedded human testis using mTOR antibody (20657-1-AP) at a dilution of 1:50 (10x objective). MCF7 cells were subjected to SDS PAGE followed by western blot with mTOR antibody (20657-1-AP) at a dilution of 1:500. –– Type Rabbit Polyclonal –– Publications 19 publications –– Applications ELISA, IF, IHC, IP, WB
  • 6. 6Cardiovascular Research Focus www.ptglab.com CARDIAC TROPONIN T ANTIBODY cTnT is a cardiac regulatory protein involved in the control of calcium-mediated interaction between actin and myosin. –– Antibody Name cTnT –– Catalog Number 15513-1-AP Immunofluorescent analysis of (4% PFA) fixed mouse heart tissue using cTnT antibody (15513-1-AP) at a dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Immunohistochemistry of paraffin-embedded human heart using cTnT antibody (15513-1-AP) at a dilution of 1:50 (40x objective). Mouse heart tissue was subjected to SDS PAGE followed by western blot with cTnT antibody (15513-1-AP) at a dilution of 1:1000. –– Type Rabbit Polyclonal –– Publications 5 publications –– Applications ELISA, IF, IHC, WB Product Focus
  • 7. 7Cardiovascular Research Focus www.ptglab.com CARDIO-RELATED ANTIBODIES Antibody Name Catalog Number Applications Publications ACTA2/smooth muscle actin 14395-1-AP ELISA, FC, IF, IHC, IP, WB 57 CD31 (PECAM-1) 11265-1-AP ELISA, FC, IF, IHC, IP, WB 15 MYL7 17283-1-AP ELISA, IF, IHC, IP, WB 1 Myosin light chain 2 10906-1-AP ELISA, FC, IF, IHC, IP, WB 44 Immunohistochemistry of paraffin-embedded human heart tissue slide using ACTA2 antibody (14395-1-AP) at a dilution of 1:5000 (40x objective). Immunofluorescent analysis of (-20ºC Ethanol) fixed C2C12 cell using ACTA2 antibody (14395-1-AP) at a dilution of 1:50. Immunohistochemistry of paraffin-embedded human lung cancer using PECAM1,CD31 antibody (11265-1-AP) at a dilution of 1:50 (10x objective). Immunofluorescent analysis of (4% PFA) fixed mouse heart tissue using MYL2 antibody (10906-1-AP) at a dilution of 1:50. Immunofluorescent analysis of (4% PFA) fixed mouse heart tissue using MYL7 antibody (17283-1-AP) at a dilution of 1:50.
  • 8. 8Cardiovascular Research Focus www.ptglab.com $99 CONTROL ANTIBODIES Popular tag/control antibodies are just $99 each. GAPDH, beta Tubulin, and 6*His tag antibodies included. See the full list of tag/control antibodies at ptglab.com PROMOTION Corn whole-plant tissue was subjected to SDS PAGE followed by western blot with GAPDH antibody (60004-1-Ig) at a dilution of 1:10000. Immunofluorescent analysis of HepG2 cells using beta- Tubulin antibody (66240-1- Ig) at a dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Mouse IgG(H+L).
  • 9. 9Cardiovascular Research Focus www.ptglab.com CONTACT US proteintech@ptglab.com europe@ptglab.com service@ptglab.com Available 24 hours via Live Chat and 9–5 (CDT) via phone. Proteintech Group Proteintech Europe Proteintech Support US Head Office United Kingdom China Office Please visit us at www.ptglab.com for more information about our antibodies and technical tips.