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Financial Plan
SAPHVIDTM : For Early detection of Pre-eclampsia




Ms. H. Gwani
Ms. S. Jain
Ms. V. Varkey
Mr. A. Awosusi
Mr. D. Igwe
Mr. P. Waghmare
Mission:

  To provide innovative point of care diagnostic products for early detection of
                          pregnancy related disorders
Vision:

 To become the leading experts for providing diagnostic solutions in the field of
                                    obstetrics
• 10% of all pregnancies

• Costs global health care system 2 billion GBP/year

• Pre-mature births (UK): 300 million GBP

• 8 deaths/year (UK)




*National Health Services, 2009
TM



Technology:

Involves three biomarkers: sEng, Plgf and sflt.

Intended Use:

Early detection of Pre-eclampsia.


Device Used:

Triage Meter
•To determine capital structure (Operating budget)

• To help the company frame financial policies as regards cash control,
lending and borrowing

•To aid maximal utilization of the limited resources made available to the
company

•To determine the NPV of G7 Diagnostics

•To forecast the profit for the forthcoming years

•To obtain the cash flow pattern & determine time for break even

•To decide G7 exit strategy
•G7 uses the Last in first out (LIFO) strategy for
marketing in UK


•Straight line depreciation
•R&D, Clinical trials and Regulatory approvals: 7 years


•Manufacturing and sales (sub-contracted): 8th year- 13th year


•Annual depreciation rate on the capital items: 15%


•Corporation tax rate: 18%


•Partnered with Alere Inc. (Device manufacturer)
Gantt Chart
                         ACTIVITY                             Year 1 Year 2 Year 3 Year 4 Year 5 Year 6 Year 7 Year 8 Year 9 Year 10 Year 11 Year 12 Year 13


Development (internal)

GMP manufacture pilot scale (subcontracted)

Clinical trials (subcontracted)

Regulatory approval (subcontracted)

Full scale GMP manufacture (subcontracted)

Internal Quality Control and Customer Support (internal)


                   Patent filing schedule
                                                 Patent 1

                                                            File    PCT    National
                                                                           Europe
                                                                           USA
Starting sales prices GBP per unit
 Country/             (GBP):
 Region
 UK                       40
 Europe                   40
 China                    37
 USA                      42
 India                    35
 Africa                   35


Cost per unit to manufacturer:

•8th year: £2.50
•11th year: £ 2.40
reduces further by £0.05 per annum thereafter.
KEY PERFORMANCE IN
Sales Volume
                     350
                     300
                     250                                                                        UK
No. of units (000)




                     200                                                                        Rest of Europe
                     150                                                                        China

                     100                                                                        USA
                                                                                                India
                     50
                                                                                                Africa
                       0
                           year 8   year 9 year 10 year 11 year 12 year 13
                                                                                                                               Sales revenue
                                                Years
                                                                                     12,000

                                                                                     10,000
                                                                 Revenue GBP (000)




                                                                                      8,000                                                         UK
                                                                                                                                                    Rest of Europe
                                                                                      6,000
                                                                                                                                                    China
                                                                                      4,000                                                         USA
                                                                                      2,000                                                         India
                                                                                                                                                    Africa
                                                                                         0
                                                                                              Year 8     year 9   year 10 Year 11 Year 12 Year 13
                                                                                                                       Years
Retained profit/ loss
                25,000



                20,000



                15,000
GBP '000




                10,000

                                                                                                          RETAINED PROFIT / (LOSS)
                 5,000



                     0



                (5,000)
                           1     2     3     4     5      6    7      8      9    10    11   12    13
 RETAINED PROFIT / (LOSS) (304) (169) (335) (429) (526) (243) (315) (415)   214 1,956 6,386 12,16 20,97

                                                              Year
Cummulative Cash flow (2011- 2023)
                                                                            Cash flow (2011-2023)
            45000
                                                                25000

            40000
                                                    CUMMULATI
            35000                                   VE          20000
                                                    CASHFLOW

            30000
                                                                15000
            25000
GB Pounds




            20000                                               10000                                   CASHFLOW

            15000

                                                                 5000
            10000
                            BREAK-EVEN
                            POINT
             5000
                                                                    0

               0                                                        1 2 3 4 5 6 7 8 9 10 11 12 13

                    1 2 3 4 5 6 7 8 9 10 11 12 13                                   Year
            -5000             Year                              -5000
Cumulative Cash flow
       Cash flow
Year                    GBP( ‘000)
       GBP( ‘000)

 1         (383.9)             (383.9)
 2         (212.4)             (596.3)
 3         (368.6)             (964.9)      Pay back period:
 4         (450.3)            (1,415.2)
                                            10 years+ (1954/ 6384)
 5         (536.3)            (1,951.5)
 6         (191.8)            (2,143.3)
                                            Approx. 10 years and 4
 7         (294.4)            (2,437.6)
                                            months
 8         (395.1)            (2,832.7)
 9           219.6            (2,613.1)
 10        1,953.5             (659.6)
 11        6,383.9             5,724.2
 12       12,162.3            17,886.5
 13       20,973.6            38,860.1
Costs GBP ('000)

                  700


                  600


                  500
Cost GBP ('000)




                  400

                                                       Costs GBP (000)
                  300


                  200


                  100


                    0
                        1   2      3         4     5
                                 Years
Total research expenditure
                 400
                 350
                 300
Cost GBP (000)




                 250
                  200
                  150
                  100
                   50
                       0
                           1   2   3   4       5      6    7   8   9
                                       Years (2011-2023)               10   11   12   13
S.No.         Head count                  activity         Duration (year)    Salary per annum             Working pattern
                                                                                                 2 days per week during research, 1
 1      CSO                       Till pilot scale GMP            5               55,000         day per week for manufacturing
 2      Design consultant         Till pilot scale GMP            5             950 per day      2 days per week
 3      Scientist (Ph.d.)         Till pilot scale GMP            5               26,000         Full time
 4      Scientist (B.Sc.)         Till development                5               20,000         Full time
 5      CEO                       Entire project                  13              70,000         1 day per week
 6      Assistant                 From pilot scale             3rd year           23,000         1 day per week
 7      General Manager           Entire project                  13              55,000         2 days/week
 8      Assistant                 Entire project               2nd year           18,000         2 days/ week
        QC maufacturing                                   4-5 year and from
 9      manager                   Varies                       8thyear            55,000         Full time
 10     Assistant                 From manufacturing           8th year           18,000         Full time
 11     Assistant                 From manufacturing          11th year           18,000         Full time
 12     Finance Manager           Entire project               13 years           55,000         1 day per week
 13     Assistant                 1 year before sales          7th year           18,000         1 day per week
        Business Develoment
 14     Analyst                   Entire project                 17               50,000         1 day per week
        Sales and Marketing       1 yr. before start of
 15     director                  product manufacture         7th year            55,000         2 days per week
 16     Assistant 1               Same as director            8th year            18,000         Full time
 17     Assistant 2               Same as director            9th year            18,000         Full time
        Customer support          After sales and
 18     Officer                   marketing                   8th year            25,000         Full time
 19     Assistant                 When sales start            8th year            18,000         Full time
 20     Sales and order officer   Year when sales start       8th year            25,000         1 day per week
2011-2023 Total Managemt/Admin cost (£'000)
                £800.00

                £700.00

                £600.00

                £500.00
Cost in £'000




                £400.00

                £300.00

                £200.00

                £100.00

                  £0.00
                          1   2      3    4    5    6         7           8   9   10   11   12   13
                                                        Year 2011- 2023
S.No.             Phase       Duration   Estimated Cost involved
                               (years)         GBP (‘000)

1       Research and            3.5              1,273
        development

2       GMP pilot scale         1.5               781
        manufacture

3       Clinical trials         1.5               409

4       Regulatory approval     0.5               160


5       Full scale GMP           5               3,846
        manufacture
• Exit at the end of 13th year

•Reasons:
     - Enough profit to cover all the expenses
     - Fierce competition
     - New upcoming technologies

•Possible acquirers: Alere, Roche, Perkin Elmer
• According to our financial analysis:

• Break even: 10th year

• At the end of year 13:
     • Sales: GBP 42.8 million
     • Net present value: GBP 11.1 million
     • Cummulative Cash flow: GBP 38.8 million
G7 Financial Plan

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G7 Financial Plan

  • 1. Financial Plan SAPHVIDTM : For Early detection of Pre-eclampsia Ms. H. Gwani Ms. S. Jain Ms. V. Varkey Mr. A. Awosusi Mr. D. Igwe Mr. P. Waghmare
  • 2. Mission: To provide innovative point of care diagnostic products for early detection of pregnancy related disorders Vision: To become the leading experts for providing diagnostic solutions in the field of obstetrics
  • 3. • 10% of all pregnancies • Costs global health care system 2 billion GBP/year • Pre-mature births (UK): 300 million GBP • 8 deaths/year (UK) *National Health Services, 2009
  • 4. TM Technology: Involves three biomarkers: sEng, Plgf and sflt. Intended Use: Early detection of Pre-eclampsia. Device Used: Triage Meter
  • 5. •To determine capital structure (Operating budget) • To help the company frame financial policies as regards cash control, lending and borrowing •To aid maximal utilization of the limited resources made available to the company •To determine the NPV of G7 Diagnostics •To forecast the profit for the forthcoming years •To obtain the cash flow pattern & determine time for break even •To decide G7 exit strategy
  • 6. •G7 uses the Last in first out (LIFO) strategy for marketing in UK •Straight line depreciation
  • 7. •R&D, Clinical trials and Regulatory approvals: 7 years •Manufacturing and sales (sub-contracted): 8th year- 13th year •Annual depreciation rate on the capital items: 15% •Corporation tax rate: 18% •Partnered with Alere Inc. (Device manufacturer)
  • 8. Gantt Chart ACTIVITY Year 1 Year 2 Year 3 Year 4 Year 5 Year 6 Year 7 Year 8 Year 9 Year 10 Year 11 Year 12 Year 13 Development (internal) GMP manufacture pilot scale (subcontracted) Clinical trials (subcontracted) Regulatory approval (subcontracted) Full scale GMP manufacture (subcontracted) Internal Quality Control and Customer Support (internal) Patent filing schedule Patent 1 File PCT National Europe USA
  • 9. Starting sales prices GBP per unit Country/ (GBP): Region UK 40 Europe 40 China 37 USA 42 India 35 Africa 35 Cost per unit to manufacturer: •8th year: £2.50 •11th year: £ 2.40 reduces further by £0.05 per annum thereafter.
  • 11. Sales Volume 350 300 250 UK No. of units (000) 200 Rest of Europe 150 China 100 USA India 50 Africa 0 year 8 year 9 year 10 year 11 year 12 year 13 Sales revenue Years 12,000 10,000 Revenue GBP (000) 8,000 UK Rest of Europe 6,000 China 4,000 USA 2,000 India Africa 0 Year 8 year 9 year 10 Year 11 Year 12 Year 13 Years
  • 12. Retained profit/ loss 25,000 20,000 15,000 GBP '000 10,000 RETAINED PROFIT / (LOSS) 5,000 0 (5,000) 1 2 3 4 5 6 7 8 9 10 11 12 13 RETAINED PROFIT / (LOSS) (304) (169) (335) (429) (526) (243) (315) (415) 214 1,956 6,386 12,16 20,97 Year
  • 13. Cummulative Cash flow (2011- 2023) Cash flow (2011-2023) 45000 25000 40000 CUMMULATI 35000 VE 20000 CASHFLOW 30000 15000 25000 GB Pounds 20000 10000 CASHFLOW 15000 5000 10000 BREAK-EVEN POINT 5000 0 0 1 2 3 4 5 6 7 8 9 10 11 12 13 1 2 3 4 5 6 7 8 9 10 11 12 13 Year -5000 Year -5000
  • 14. Cumulative Cash flow Cash flow Year GBP( ‘000) GBP( ‘000) 1 (383.9) (383.9) 2 (212.4) (596.3) 3 (368.6) (964.9) Pay back period: 4 (450.3) (1,415.2) 10 years+ (1954/ 6384) 5 (536.3) (1,951.5) 6 (191.8) (2,143.3) Approx. 10 years and 4 7 (294.4) (2,437.6) months 8 (395.1) (2,832.7) 9 219.6 (2,613.1) 10 1,953.5 (659.6) 11 6,383.9 5,724.2 12 12,162.3 17,886.5 13 20,973.6 38,860.1
  • 15. Costs GBP ('000) 700 600 500 Cost GBP ('000) 400 Costs GBP (000) 300 200 100 0 1 2 3 4 5 Years
  • 16. Total research expenditure 400 350 300 Cost GBP (000) 250 200 150 100 50 0 1 2 3 4 5 6 7 8 9 Years (2011-2023) 10 11 12 13
  • 17. S.No. Head count activity Duration (year) Salary per annum Working pattern 2 days per week during research, 1 1 CSO Till pilot scale GMP 5 55,000 day per week for manufacturing 2 Design consultant Till pilot scale GMP 5 950 per day 2 days per week 3 Scientist (Ph.d.) Till pilot scale GMP 5 26,000 Full time 4 Scientist (B.Sc.) Till development 5 20,000 Full time 5 CEO Entire project 13 70,000 1 day per week 6 Assistant From pilot scale 3rd year 23,000 1 day per week 7 General Manager Entire project 13 55,000 2 days/week 8 Assistant Entire project 2nd year 18,000 2 days/ week QC maufacturing 4-5 year and from 9 manager Varies 8thyear 55,000 Full time 10 Assistant From manufacturing 8th year 18,000 Full time 11 Assistant From manufacturing 11th year 18,000 Full time 12 Finance Manager Entire project 13 years 55,000 1 day per week 13 Assistant 1 year before sales 7th year 18,000 1 day per week Business Develoment 14 Analyst Entire project 17 50,000 1 day per week Sales and Marketing 1 yr. before start of 15 director product manufacture 7th year 55,000 2 days per week 16 Assistant 1 Same as director 8th year 18,000 Full time 17 Assistant 2 Same as director 9th year 18,000 Full time Customer support After sales and 18 Officer marketing 8th year 25,000 Full time 19 Assistant When sales start 8th year 18,000 Full time 20 Sales and order officer Year when sales start 8th year 25,000 1 day per week
  • 18. 2011-2023 Total Managemt/Admin cost (£'000) £800.00 £700.00 £600.00 £500.00 Cost in £'000 £400.00 £300.00 £200.00 £100.00 £0.00 1 2 3 4 5 6 7 8 9 10 11 12 13 Year 2011- 2023
  • 19. S.No. Phase Duration Estimated Cost involved (years) GBP (‘000) 1 Research and 3.5 1,273 development 2 GMP pilot scale 1.5 781 manufacture 3 Clinical trials 1.5 409 4 Regulatory approval 0.5 160 5 Full scale GMP 5 3,846 manufacture
  • 20. • Exit at the end of 13th year •Reasons: - Enough profit to cover all the expenses - Fierce competition - New upcoming technologies •Possible acquirers: Alere, Roche, Perkin Elmer
  • 21. • According to our financial analysis: • Break even: 10th year • At the end of year 13: • Sales: GBP 42.8 million • Net present value: GBP 11.1 million • Cummulative Cash flow: GBP 38.8 million

Hinweis der Redaktion

  1. Year 5: Investments to be made on human resources. We invest on people.
  2. We can see that the cumulative cash flow becomes positive in the 11th year. We have assumed that the cash flows evenly over the year, the precise payback period becomes: (Refer to slide)
  3. At the end of yr. 13 we plan to sell our technology.