power point presentation on antitubercular therapy from pharmacology aspect

1. Anti Tubercular Therapy
Dr N Preetha MD
Assistant Professor
Department of Pharmacology
GDMC

2. John Hopkins university study…
TB kills 4,109 people a day.
Vs
1,449 people a day dying due to covid
Despite being both preventable and curable, TB kills around 1.5 million people each year, more than any other infectious
disease.

3. ‘Not our problem'
• Around five percent of the 9.5 million people who contract TB
each year are resistant to ATT drugs

46. Tubercular infection Effective drugs
Rapidly growing, high bacillary load H > R, E , S
Slow growing- intracellular macrophages Z > H,R,E & S -
Spurters- caseous material R
Dormant Nil (bedaquiline)

56. Monodrug resistant TB

57. Polydrug resistant TB

58. INH resistant TB

60. Extensive drug-resistant TB

62. Role of corticosteroids in TB
• Seriously ill
• Hypersensitivity
• Extrapulmonary TB- prevent exudation/strictures
• AIDS – severe TB

65. TUBERCULOSIS PREVENTIVE TREATMENT

66. TPT

67. Mycobacterium Avium Complex