coagulation disorder pathophysiology clinical presentationand mangement

5. PT/INR
aPTT
BLEEDING TIME
TT
1° HEMOSTASIS 2° HEMOSTASIS

7. NORMAL BLEEDING
TIME
NORMAL PLATELET
COUNT

11. Residual activity of F8 or F9

13. Pseudotumor syndrome- Retroperitoneal hemorrhages can accumulate large
quantities of blood with formation of masses with calcification and
inflammatory tissue reaction.

15. WITHOUT TREATMENT, SEVERE HEMOPHILIA HAS A LIMITED LIFE EXPECTANCY.

19. • The formation of alloantibodies to FVIII or FIX
is currently the major complication of
hemophilia treatment
• The clinical diagnosis of an inhibitor is
suspected when patients do not respond to
factor replacement at therapeutic doses.
• lnhibitors increase both morbidity and
mortality in hemophilia .

26. Purpura Fulminans

27. • THE MORTALITY RANGES FROM 30 TO >80%
DEPENDING ON THE UNDERLYING DISEASE, THE
SEVERITY OF THE DIC AND THE AGE OF THE
PATIENT.

30. Differential Diagnosis