This document summarizes different classes of antihypertensive medications. It lists examples of: 1) ACE inhibitors such as captopril, enalapril, and lisinopril; angiotensin receptor blockers such as losartan and irbesartan; and calcium channel blockers such as amlodipine, nifedipine, and diltiazem. 2) Diuretics such as chlorthiazide, furosemide, and spironolactone. Beta blockers such as propranolol and atenolol are also mentioned. 3) Other antihypertensives mentioned include alpha blockers, central sympathol

1. SCHEDULE H
Presented By:-
Stefin Mathew and Aswathy Saji
3 rd year pharm D

4. Eg; Antihypertensives
• ACE Inhibitors
a)Sulfhydryl containing inhibitors;
eg: Captopril
b)Dicarboxylate containing inhibitors ;
eg: Enalapril, Lisinopril, Ramipril, Trandopril, Spirapril,
Moxipril
c)Phosphonate containing inhibitor;
eg: Fosinopril
• Angiotensin antagonist;
eg: Losartan ,Irbesartan, Candesartan, Telmisartan,
Valsartan

5. • Calcium Channel Blockers
a)1,4-dihydro pyridine;
eg: Nifedipine ,Nimodipine ,Amlodipine ,Nislodipine,
Felodipine ,Nicardipine ,Benidipine ,Lacidipine
b)phenyl alkyl amine;
eg :Verapamil
c)benzothiazepine;
eg: Diltiazem
d)diamino propanol ether;
eg :Bepridil

6. • Diuretics
eg: chlorthiazide ,hydrochlorthiazide ,furosemide
,spironolactone
Beta adrenergic blockers
eg: propranolol ,atenolol ,metoprolol
Mixed alpha and beta- Adrenergic blockers
eg: labetolol ,carvedilol.
Alpha Adrenergic blockers
eg: prazosin, phenoxybenzamine, phentolamine
Centrally acting sympatholytic agents
eg: clonidine, methyl dopa

7. VASODIALATORS;
eg: hydralazine, minoxidil, diazoxide, sodium nitroprusside
Adrenergic Neuron Blockers
eg: guanethidine, reserpine, pethanidine, bretylium.

8. THANK YOU