Infertility is the inability of a couple to become expectant with a child (in spite of of any cause) after 1 year of unguarded sexual intercourse (sans any birth control methods).
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In vitro fertilization
1. IN-VITRO FERTILIZATION
Infertility
Infertility is the inability of a couple to become expectant with a child (in
spite of of any cause) after 1 year of unguarded sexual intercourse (sans
any birth control methods).
Infertility Causes
Age: A woman becomes reproductively challenged as she progresses into
her fifth decade of life (age 40-49 years). Among men, as they grow old,
levels of testosterone fall and sperm motility and quality changes,
considerably.
Endometriosis: In this abnormality, the uterine tissue overgrows, outside
uterus and may subsequently damage the fallopian tubes and ovaries.
Pelvic Inflammatory syndrome: Sexually transmitted diseases may be
linked with pelvic inflammatory disease (PID) and damage a woman's
fallopian tubes.
Environmental and occupational risk factors: Exposure to hazardous
chemicals like lead, heavy metals, and sometimes pesticides has also been
associated with male infertility. Other factors like extreme exposure to heat,
ultrasound and microwave may also be responsible.
Miscellaneous factors: Excessive tobacco and alcohol consumption,
obesity, thyroid disorders might also be responsible.
2. IVF TREATMENT
IVF or In-Vito Fertilization is sought by couples when every other
possible option fails like drug therapy, surgical treatments, IUI, ICSI etc.
In -vitro fertilization refers to fertilization accomplished outside the
body, that is, in a laboratory dish or test tube. IVF is mainly used in cases
where infertility results due to blocked fallopian tubes or inexplicable
infertility.
IMPORTANT CONSIDERATIONS
This procedure demands untiring patience as at times, multiple
attempts maybe required since the success rate varies from person to
person
Usually multiple embryos are created and then the healthiest of them
is used for transfer and implantation. Therefore the fate of the
remaining embryos remains questionable, though most of the IVF
clinics in India have a provision for embryo freezing.
Sometimes, IVF becomes a tedious procedure involving a multitude of
ultrasounds, drugs, tests and so on. One must have a positive bent of
mind and high will power to come out of it as a winner
I.V.F COURSE OF ACTION
It is a series of carefully supervised steps:
OVARIAN STIMULATION BY THE USE OF FERTILITY DRUGS: In a
typical monthly cycle, a female produces one egg but in a fertility
compromised case, more than one egg is required so that the
possibility of fertilization with the sperm enhances manifold. For this,
hormone therapy is started with Gonadotropins and FSH (Follicle
Stimulating Hormone). Eggs are stocked up in the fluid filled sacs
3. known as follicles. FSH is indispensable for multiple oocyte production
whereas Gonadotropins estimate the egg production by the ovaries.
Ultrasounds and blood estrogen levels are examined regularly to keep
a trail of the development inside the body. Trans-Vaginal Scan is done
following an injection of HCG, 36 hours prior to egg collection, for
maturation of eggs.
OVUM COLLECTION: With ultrasound guided needle aspiration
technique, mature eggs are collected, under IV sedation.
FERTILIZATION (IN-VITRO): A few hours preceding the egg
retrieval, semen is collected and processed so that the strongest
sperms can be obtained; which are then hatched with the recovered
eggs in the laboratory in a culture medium for fertilization into
embryos.
EMBRYO RELOCATION INTO THE UTERUS: The embryo transfer
procedure is a day care procedure without introducing anesthesia. The
embryo is picked up into a very superior catheter, which is
impregnated through the cervix, into the uterus, and the embryo is
transferred inside the uterine cavity.
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