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200 PRACTICAL DIABETES VOL. 32 NO. 6 COPYRIGHT © 2015 JOHN WILEY & SONS
Practice point
Introduction
Diabetes is covered by the Equality Act
2010, which makes it illegal for
employers to refuse a job to someone
simply because of their disability.1 As a
result of this act, people with diabetes
can no longer be banned from a par-
ticular role simply because they have
diabetes; instead their fitness to do the
job must be individually assessed. The
only employer exempt from the
Equality Act is the Armed Forces,
where a blanket ban on recruiting
people with diabetes still applies.2
Some occupations have strict med-
ical standards that people with dia-
betes may not be able to meet. These
usually apply where a job is unusually
risky, e.g. because it involves operating
heavy machinery or vehicles, with a
risk of harm to the employee or others
in case of sudden incapacity. The most
common reason for people with dia-
betes not meeting medical standards is
the potential risk of hypoglycaemia.
For example, historically, people with
type 1 diabetes or those with type 2
diabetes who require insulin in the
UK are not allowed to become train
drivers or commercial airline pilots.
Vehicle licensing regulations are strict
relating to HGV and PSV licensing;
however, times change and there are
now several people with type 1 dia-
betes who have been allowed to fly civil
aircraft.3 The Faculty of Occupational
Medicine of the Royal College of
Physicians has also published guidance
for assessing fitness for blue light
driving (emergency drivers, e.g. police
officers, fire crews or paramedics),
including drivers on insulin.4
This article focuses in particular
on the safety of individuals with type
1 or type 2 diabetes requiring insulin
being able to drive trains, and should
therefore be seen as a suggestion of
guidance in order to trigger debate
on the matter.
In relation to train driving, the
current legislation which provides
medical standards for train drivers
is the ‘Train Driving Licences
and Certificates Regulations 2010’
(TDLCR 2010).5
This legislation states
that: ‘Drivers must not be suffering
from any medical conditions or be
taking any medication, drugs or sub-
stances which are likely to cause – (a)
a sudden loss of consciousness, (b) a
reduction in attention or concentra-
tion, (c) sudden incapacity, (d) a loss
of balance or coordination.’
The document ‘Guidance on
Medical Fitness for Railway Safety
Critical Workers’ GOGN3655 Issue 2
(2014) further states that: ‘Modern
treatments and risk assessment
methods have enabled some insulin
treated individuals to perform safety
critical roles just as well as other
people.’ It goes on to say that:
‘People with diabetes have success-
fully challenged employers who
sought to exclude them from jobs
simply because they were “diabetic”,
Train driving and diabetes – keeping
safety on track
Abstract
Despite disability legislation, some people with diabetes (particularly those taking insulin) still
experience discrimination in the work that they are allowed to perform.
Some occupations have strict medical standards that people with diabetes may not be
able to meet.These usually apply where a job is unusually risky, e.g. because it involves
operating heavy machinery or vehicles, with a risk of harm to the employee or others in case
of sudden incapacity. People with diabetes have successfully challenged employers who
sought to exclude them from jobs simply because they were ‘diabetic’, rather than assessing
them as individuals.
We look at the phenomenon of diabetes control related to train driving and the criteria
that should be achieved to ensure safety for both the individual and their passengers.
Copyright © 2015 John Wiley & Sons.
Practical Diabetes 2015; 32(6): 200–203
Key words
diabetes mellitus; hypoglycaemia; insulin; safety critical work; train driving
Dr Paul Grant
Consultant Diabetologist, Royal Sussex County
Hospital, Brighton, UK
Dr Harry Phoolchund
Consultant Occupational Physician, Sigma
Occupational Health Ltd, London, UK
Correspondence to:
Dr Paul Grant, Consultant Diabetologist, Royal Sussex
County Hospital, Eastern Road, Brighton BN2 5BE,
UK; email: drpaul.grant@doctors.org.uk
Dr Harry Phoolchund, Consultant Occupational
Physician, Sigma Occupational Health Ltd, 52
Wimborne Drive, Pinner, Middlesex HA5 1NQ, UK;
email: harry.phoolchund@sigmaoh.co.uk
Received: 13 April 2015
Accepted in revised form: 13 May 2015
PRACTICAL DIABETES VOL. 32 NO. 6 COPYRIGHT © 2015 JOHN WILEY & SONS 201
Train driving and diabetes – keeping safety on track
Practice point
rather than assessing them as indi-
viduals. This means that a “blanket
ban” for people with diabetes is no
longer acceptable, except where
there is a legal requirement.’6
Example case history
A 36-year-old female employee has
been under the care of the hospital
diabetes service. She was originally
diagnosed with type 1 diabetes eight
years earlier. At that time she was
already working as a train conductor
and was concerned that she would
lose her job as a consequence of her
new diagnosis – however, this was not
the case and she was able to continue
working so long as there was regular
ongoing diabetes team and occupa-
tional health review. She has a
long held ambition to become a
train driver.
Over time, her overall diabetes
control was variable but improved
following attendance on the local
Type 1 Diabetes Structured Educ-
ation course – this seeks to help
improve diabetes self-management
through the principles of carbohy-
drate counting and insulin dose
adjustment. Figure 1 demonstrates
the longitudinal pattern of her
HbA1c over time.
Day-to-day capillary blood glucose
monitoring appeared stable, with a
pre-meal range of 3.7–6.8mmol/L
and a 2 hour post-meal range of
5.2–8.5mmol/L. There has fortu-
nately been little in the way of hypo-
glycaemia. Certainly, no episodes
requiring third party assistance have
been reported and hypoglycaemia
awareness remained intact. The
patient is keen and determined to
apply for a role as a train driver and,
given the fact that her overall control
was good, it has been difficult to find
a reason not to explore this. There
was no clinical requirement to con-
sider the use of insulin pump therapy
or a continuous glucose monitoring
system (CGMS) in view of the fact that
regular, fastidious blood glucose
monitoring was ongoing and no
micro- or macrovascular complica-
tions of diabetes had developed over
time. Following discussion, the local
diabetes team and the occupational
health team at her place of employ-
ment are monitoring her diabetes
status until the employer makes a
decision regarding train driving for
employees on insulin. This is a sensi-
tive issue at the moment as no train
operating company in the UK has so
far allowed train driving on insulin,
and understandably relates to the fit-
ness to perform safety critical work
alongside the concern of insulin as a
‘high-risk’ medication in terms of
hypoglycaemia susceptibility.
Development of occupational
health guidance
The ‘Guidance on Medical Fitness for
Railway Safety Critical Workers’
GOGN 3655 gives general guidance
on railway workers who have dia-
betes.6 Taking this into account and
the available literature on diabetes
treated with insulin, particularly the
risks of sudden incapacity due to
hypoglycaemia and the concern about
hypoglycaemia without warning, the
following suggested approach has
been developed by the authors to
reflect current expert knowledge and
published referenced resources.3,7–11
1. The following information is
necessary before a train driver with
diabetes treated with insulin is
allowed to be considered for driving.
• The employee, if they have type 1
diabetes, must have been stable on
insulin for at least six months.
• If the employee has type 2 diabetes
requiring insulin, he/she should
have had a stable regimen for at least
three months.
• In any driver taking insulin, the
introduction of a new drug or class of
insulin should trigger a further
period of observation of up to three
months for a new insulin, and two
months for the addition of an oral
hypoglycaemic medication.
• A report should be obtained from
the employee’s diabetes consultant
covering the previous three years or
since diagnosis, whichever is sooner,
with the following information:
– History of diabetes, evidence of
any complications (renal, neurologi-
cal, ophthalmological) and any other
medical conditions.
– Confirmation that the employee
has adequate awareness of clinical
symptoms of impending hypogly-
caemia.
• There should be a record of regu-
lar blood sugars throughout the day
(essentially by the use of a recording
glucose meter with a non-deletable
memory with three months’ capacity
to allow review); the blood glucose
target to fall between 5mmol/L and
10mmol/L for over 90% of the read-
ings, and an HbA1c of less than
69mmol/mol (8.5%).
• Continuous glucose monitoring
should be seen as essential certainly
for a baseline assessment and, in terms
of ongoing usage, can be considered if
supported and agreed by the treating
consultant diabetologist. Device speci-
fications to be determined by recom-
mendation from the clinician.
Figure 1. Longitudinal pattern of HbA1c over time in the example case history
80
64
48
32
16
0
Lower range Upper range Value
05/11/2009 27/10/2011 26/09/2012 24/12/2013
HbA1c(mmol/mol)
26/01/2011 20/03/2012 29/01/2013 07/04/2014
Sample received
• A history of hypoglycaemia that
resulted in a seizure, loss of conscious-
ness, impaired cognitive function or
required the assistance of others
within the previous year, unless there
is a clear reason, should make the
employee unfit for train driving.
• Information should be sought as to
the employee’s awareness of hypogly-
caemia. If the record of blood sugars
shows levels of <3.5mmol/L without
any symptoms, this should be a cause
for concern.
2. Commencement of train driving
can only be undertaken with
compliance to the following restric-
tions/conditions.
• The employee should take his/her
blood sugar at the start of a shift and
every 2 hours during the shift. This
should be by means of a non-
deletable recording glucose meter
with a three months’ memory capac-
ity. It is the responsibility of the line
manager to always check and estab-
lish if a blood glucose diary is being
maintained and to refer to occupa-
tional health (OH) if the diary is not
being maintained or if there is other
cause for concern. If there is any lack
of clarity, then a low threshold for the
use of continuous glucose monitor-
ing is advised. Pending an OH assess-
ment, the employee is restricted
from driving.
• On commencing a shift, the
employee should inform the line
manager that he/she is fit to under-
take train driving.
• If at any time during the shift the
employee feels hypoglycaemic or the
blood glucose is found to be less
than 5mmol/L on testing, he/she
should stop driving and inform the
line manager.
• Following any feelings of hypogly-
caemia, or blood glucose less than
5.0mmol/L, driving should not
resume until at least 45 minutes after
consuming an amount of rapidly
absorbable glucose equivalent to 15g
of glucose (e.g. 4 ‘Glucotabs’, which
contains 4g of fast-acting glucose per
tablet) and a normal blood glucose
(>5mmol/L) has been recorded. For
such a situation, every employee con-
cerned should have an emergency
supply of fast-acting glucose on
his/her person or within easy reach
within the driver’s cab. In addition, a
slow-acting carbohydrate (10–20g)
should be consumed to help
maintain the blood glucose level
above 5mmol/L and to prevent it
from falling again, e.g. a slice of
bread, a piece of fruit, a couple of
digestive biscuits or a packet of crisps.
• Alcohol should be avoided during
the 24 hours preceding a shift.
• Changes in the insulin regimen or
the introduction of a new oral hypo-
glycaemic agent are a period of high
risk for hypoglycaemic episodes. If
any changes of insulin regimen, or
new hypoglycaemic agent, are pro-
posed, the employee should be
restricted from driving until review in
OH: this is likely to lead to a period
of restriction from driving for up to
two to three months.
• If the employee suffers a hypogly-
caemic episode requiring the assis-
tance of others, whether on duty or
off work, he/she should stop driving
pending a review in OH.
• An update report should be
obtained annually from the
employee’s diabetes consultant.
• There should be close collabora-
tion between OH, the employee, the
line manager and human resources
(HR) so that the following responsi-
bilities are clearly understood and
adhered to:
– The employee is responsible for
his/her own health, monitoring
his/her blood glucose as recom-
mended by OH, reporting any
adverse symptoms or hypoglycaemia
to his/her line manager.
– A signed agreement with each
driver will be proposed to ensure
each driver understands the signifi-
cant commitment he/she will have
to make.
– The line manager is responsible
to check and ensure that the blood
glucose diary is being maintained for
every shift and inform OH and
restrict the employee from driving
duties if this is not done.
– The line manager should be
aware of, and be able to accommo-
date, the following from an opera-
tional perspective: regular checks of
blood sugar during each shift, breaks
for snacks if necessary, the require-
ment not to drive if blood sugar at
any time is less than 5mmol/L or if
there is evidence of hypoglycaemia.
– HR managers and senior man-
agement within the organisation
should be fully aware of the potential
impact of having drivers on insulin
on operational capacity.
– It is also necessary to obtain the
commitment of senior management
in the organisation prior to the intro-
duction of this approach for drivers
on insulin.
Conclusions
Despite disability legislation, some
people with diabetes (particularly
those taking insulin) still experience
discrimination. If an individual is well
controlled with stable capillary glu-
cose values and no significant hypo-
glycaemia and intact awareness then,
from a medical perspective, it should
be acceptable for them to undertake
safety critical work. The 2010
Equality Act itself unfortunately does
not make a distinction with regard
to such a ‘disability’ as diabetes
between someone employed in a role
who subsequently goes on to develop
diabetes and an individual who has
pre-existing diabetes who is applying
de novo to undertake such work.
With regard to train driving, the
situation is complex: on the one hand,
it can be argued that a train driver who
is well controlled on insulin should
be able to drive. This needs to be
balanced against the operational
implications of having a train driver
on insulin: arrangements need to
be made to enable regular blood glu-
cose measurements, as recommended
above. Furthermore, the business
needs to be able to cope with rare situ-
ations of a driver being temporarily
removed from driving duties, at short
notice, in the event that the blood glu-
cose is less than 5mmol/L. At a time
when the railway sector is under enor-
mous pressure to maintain punctual-
ity, and timetables for the travelling
public, and avoid cancelling trains, the
potential business impact of a driver
on insulin needs to be considered.
Finally, there is a risk of a driver
having a hypoglycaemic episode
when driving on the mainline. With
the safety systems in place in the
driver’s cab on modern trains, the
train would normally stop, and there
would be no direct risk to passengers.
However, the impact on business con-
tinuity, and the reputational risk fol-
lowing such an incident, would be
considerable for the train operating
company (TOC). In addition, there
would be a further risk of the driver
202 PRACTICAL DIABETES VOL. 32 NO. 6 COPYRIGHT © 2015 JOHN WILEY & SONS
Train driving and diabetes – keeping safety on track
Practice point
having a hypoglycaemic episode in
an isolated situation (in the driver’s
cab) for an extended time before any
assistance (medical or otherwise) can
reach him/her.
The operational issues high-
lighted above will need to be carefully
considered by senior management in
each TOC before train driving on
insulin is allowed. Furthermore, to
our knowledge, no TOC in the UK
has yet allowed train driving on
insulin. There is a risk that the first
TOC to do so will face a number of
applications for the train driver role
from individuals who have diabetes
and are on insulin: because of disabil-
ity legislation, rejection will not be
appropriate, leading to an increasing
burden, possibly non-sustainable, on
the TOC concerned.12
The UK Civil Aviation Authority
has been through a similar process
recently, undertaking individualised
assessment of insulin treated pilots
and, subject to safety and risk analysis,
medical certification of fitness to fly
may be approved. An operational pro-
tocol requires pre-flight and hourly
in-flight blood glucose monitoring,
using conventional capillary test
strips, with results recorded in the
pilot’s log-book. CGMS measuring
interstitial glucose is presently consid-
ered insufficiently validated under
these specific circumstances.13,14 It
should be noted that this initiative
currently applies to commercial
multi-crew aviation, so that a co-pilot
in the cockpit will be present.
Modern technological approaches
to diabetes management may also
come in handy – when CGM systems
are linked to continuous subcuta-
neous insulin infusion, there is the
option to include a ‘low glucose
suspend’ function to enable insulin
delivery to be halted when there is a
marked drop in glucose levels acutely
in order to avoid the occurrence of
hypoglycaemia.15,16
We hope that the proposed guid-
ance above forms a sound basis to
help clinicians manage such patients,
for individuals with diabetes to
understand the need for exemplary
control and to provide reassurance
for TOCs, as well as act as a basis for
further discussion.
From a business perspective, an
optimal solution would be for any
decision to allow train driving on
insulin to be taken jointly by all
TOCs, with the support of the
Railway Safety and Standards Board
and the Office of Rail Regulation.
Acknowledgments
Many thanks to Professor Ken Shaw
for advice, Josie Wilson and Sara
Moore, expert Specialist Diabetes
Nurses at Brighton and Sussex
University Hospitals, and Megan
Taylor, Occupational Health Nurse
Manager.
Declaration of interests
There are no conflicts of interest
declared.
Both authors contributed equally
to the production of this document.
References
1. Equality Act 2010. www.legislation.gov.uk/ukpga/
2010/15/contents [last accessed 15 March 2015].
2. Legislative Scrutiny: Armed Forces Bill – Joint
Committee on Human Rights. www.publications.
parliament.uk/pa/jt201012/jtselect/jtrights/145/145
13.htm [last accessed 21 March 2015].
3. Heller SR, Nicholson AN. Aircrew and type 1 dia-
betes mellitus. Aviation Space & Environmental
Medicine 2006;77:454–8.
4. Faculty of Occupational Physicians of the RCP.
Guidelines for assessing fitness for blue light
driving, July 2013. www.fom.ac.uk/wp-content/
uploads/FOM-Guide-re-blue-light-driving.pdf [last
accessed 18 March 2015].
5. Office of Rail Regulation. Train Driving Licences
and Certificates Regulations 2010. TDLCR 2010.
http://orr.gov.uk/__data/assets/pdf_file/0003/4998/
train-driving-licences-regulations-2010-guidance.
pdf [last accessed 20 March 2015].
6. Rail Safety and Standards Board Limited. Guidance
on Medical Fitness for Railway Safety Critical
Workers. GOGN3655 Issue 2 (June 2014). www.
rgsonline.co.uk/Railway_Group_Standards/Traffic
%20Operation%20and%20Management/Guid
ance%20Notes/GOGN3655%20Iss%202.pdf [last
accessed 19 March 2015].
7. Graveling AJ, Frier BM. Impaired awareness of
hypoglycaemia: a review. Diabetes Metab 2010;
36:S64–S74.
8. Ogundipe OO, et al. Impaired hypoglycaemia
awareness and employment in people with type 1
diabetes. Occupational Med 2011;61:241–6.
9. Diabetes and Driving, Position Paper of the
American Diabetes Association. Diabetes Care
2014;37(Suppl 1):S97–S103.
10. Cox DJ, et al. Type 1 diabetic drivers with and
without a history of recurrent hypoglycemia-
related driving mishaps: physiological and
performance differences during euglycemia and
the induction of hypoglycemia. Diabetes Care
2010;33:2430–5.
11. Rail Safety and Standards Board Ltd. Good Practice
Guide on Rail Workers & Diabetes – Guidance for
Medical Assessors. RS/506 Issue 1 Draft 1a 2007.
12. www.diabetes.org.uk/Information-for-parents/
Growing-up/Work-and-discrimination/ [last accessed
7 March 2015].
13. Diabetes UK. Pilots with diabetes allowed to fly
commercial aircraft. www.diabetes.org.uk/About_
us/News_Landing_Page/Pilots-with-diabetes-
allowed-to-fly-commercial-aircraft/ [last accessed
23 March 2015].
14. Civil Aviation Authority. UK CAA Policy for the
Medical Certification of Pilots and ATCOs with
Diabetes. www.caa.co.uk/docs/2499/P027-Diabetic
%20Certification%20Guidance.pdf [last accessed
23 March 2015].
15. Grant P. A new approach to diabetic control: fuzzy
logic and insulin pump technology. Med Eng Phys
2007;29:824–7.
16. Wilmot E, et al. Insulin pump therapy: a practical
guide to optimising glycaemic control. Pract
Diabetes 2014;31:121–5a.
PRACTICAL DIABETES VOL. 32 NO. 6 COPYRIGHT © 2015 JOHN WILEY & SONS 203
Train driving and diabetes – keeping safety on track
Practice point
l People with diabetes on insulin
therapy need to be judged on an
individual basis when it comes to
assessing fitness to undertake safety
critical work
l No train operating company in the UK
has as yet allowed train driving to be
undertaken by individuals with
diabetes – that is, those with type 1
diabetes or type 2 diabetes
subsequently treated with insulin
l Clear parameters for safe and stable
glycaemic control, with avoidance of
hypoglycaemia are key from a safety
perspective
Key pointsOperator-presence control
A dead man’s switch is a switch that is automatically operated if the human operator
becomes incapacitated, such as through death, loss of consciousness or being bodily
removed from control.These switches are usually used as a form of fail-safe where they stop
a machine with no operator from potentially dangerous action.They are commonly used in
this manner in locomotives, lawn mowers, tractors, personal watercraft, outboard motors,
and chainsaws. On some machines, these switches merely bring the machines back to a safe
state, such as reducing the throttle to idle or applying brakes while leaving the machines still
running and ready to resume normal operation once control is re-established.With modern
railway systems, the driver is typically alone in an enclosed cab. Electrically or pneumatically
linked dead-man’s controls involve relatively simple modifications of the controller handle,
the device that regulates traction power. If pressure is not maintained on the controller, the
train’s emergency brakes are applied and the train stops.The driver does not necessarily
need to be dead for this to function

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Grant_Phoolchund-2015-Practical_Diabetes

  • 1. 200 PRACTICAL DIABETES VOL. 32 NO. 6 COPYRIGHT © 2015 JOHN WILEY & SONS Practice point Introduction Diabetes is covered by the Equality Act 2010, which makes it illegal for employers to refuse a job to someone simply because of their disability.1 As a result of this act, people with diabetes can no longer be banned from a par- ticular role simply because they have diabetes; instead their fitness to do the job must be individually assessed. The only employer exempt from the Equality Act is the Armed Forces, where a blanket ban on recruiting people with diabetes still applies.2 Some occupations have strict med- ical standards that people with dia- betes may not be able to meet. These usually apply where a job is unusually risky, e.g. because it involves operating heavy machinery or vehicles, with a risk of harm to the employee or others in case of sudden incapacity. The most common reason for people with dia- betes not meeting medical standards is the potential risk of hypoglycaemia. For example, historically, people with type 1 diabetes or those with type 2 diabetes who require insulin in the UK are not allowed to become train drivers or commercial airline pilots. Vehicle licensing regulations are strict relating to HGV and PSV licensing; however, times change and there are now several people with type 1 dia- betes who have been allowed to fly civil aircraft.3 The Faculty of Occupational Medicine of the Royal College of Physicians has also published guidance for assessing fitness for blue light driving (emergency drivers, e.g. police officers, fire crews or paramedics), including drivers on insulin.4 This article focuses in particular on the safety of individuals with type 1 or type 2 diabetes requiring insulin being able to drive trains, and should therefore be seen as a suggestion of guidance in order to trigger debate on the matter. In relation to train driving, the current legislation which provides medical standards for train drivers is the ‘Train Driving Licences and Certificates Regulations 2010’ (TDLCR 2010).5 This legislation states that: ‘Drivers must not be suffering from any medical conditions or be taking any medication, drugs or sub- stances which are likely to cause – (a) a sudden loss of consciousness, (b) a reduction in attention or concentra- tion, (c) sudden incapacity, (d) a loss of balance or coordination.’ The document ‘Guidance on Medical Fitness for Railway Safety Critical Workers’ GOGN3655 Issue 2 (2014) further states that: ‘Modern treatments and risk assessment methods have enabled some insulin treated individuals to perform safety critical roles just as well as other people.’ It goes on to say that: ‘People with diabetes have success- fully challenged employers who sought to exclude them from jobs simply because they were “diabetic”, Train driving and diabetes – keeping safety on track Abstract Despite disability legislation, some people with diabetes (particularly those taking insulin) still experience discrimination in the work that they are allowed to perform. Some occupations have strict medical standards that people with diabetes may not be able to meet.These usually apply where a job is unusually risky, e.g. because it involves operating heavy machinery or vehicles, with a risk of harm to the employee or others in case of sudden incapacity. People with diabetes have successfully challenged employers who sought to exclude them from jobs simply because they were ‘diabetic’, rather than assessing them as individuals. We look at the phenomenon of diabetes control related to train driving and the criteria that should be achieved to ensure safety for both the individual and their passengers. Copyright © 2015 John Wiley & Sons. Practical Diabetes 2015; 32(6): 200–203 Key words diabetes mellitus; hypoglycaemia; insulin; safety critical work; train driving Dr Paul Grant Consultant Diabetologist, Royal Sussex County Hospital, Brighton, UK Dr Harry Phoolchund Consultant Occupational Physician, Sigma Occupational Health Ltd, London, UK Correspondence to: Dr Paul Grant, Consultant Diabetologist, Royal Sussex County Hospital, Eastern Road, Brighton BN2 5BE, UK; email: drpaul.grant@doctors.org.uk Dr Harry Phoolchund, Consultant Occupational Physician, Sigma Occupational Health Ltd, 52 Wimborne Drive, Pinner, Middlesex HA5 1NQ, UK; email: harry.phoolchund@sigmaoh.co.uk Received: 13 April 2015 Accepted in revised form: 13 May 2015
  • 2. PRACTICAL DIABETES VOL. 32 NO. 6 COPYRIGHT © 2015 JOHN WILEY & SONS 201 Train driving and diabetes – keeping safety on track Practice point rather than assessing them as indi- viduals. This means that a “blanket ban” for people with diabetes is no longer acceptable, except where there is a legal requirement.’6 Example case history A 36-year-old female employee has been under the care of the hospital diabetes service. She was originally diagnosed with type 1 diabetes eight years earlier. At that time she was already working as a train conductor and was concerned that she would lose her job as a consequence of her new diagnosis – however, this was not the case and she was able to continue working so long as there was regular ongoing diabetes team and occupa- tional health review. She has a long held ambition to become a train driver. Over time, her overall diabetes control was variable but improved following attendance on the local Type 1 Diabetes Structured Educ- ation course – this seeks to help improve diabetes self-management through the principles of carbohy- drate counting and insulin dose adjustment. Figure 1 demonstrates the longitudinal pattern of her HbA1c over time. Day-to-day capillary blood glucose monitoring appeared stable, with a pre-meal range of 3.7–6.8mmol/L and a 2 hour post-meal range of 5.2–8.5mmol/L. There has fortu- nately been little in the way of hypo- glycaemia. Certainly, no episodes requiring third party assistance have been reported and hypoglycaemia awareness remained intact. The patient is keen and determined to apply for a role as a train driver and, given the fact that her overall control was good, it has been difficult to find a reason not to explore this. There was no clinical requirement to con- sider the use of insulin pump therapy or a continuous glucose monitoring system (CGMS) in view of the fact that regular, fastidious blood glucose monitoring was ongoing and no micro- or macrovascular complica- tions of diabetes had developed over time. Following discussion, the local diabetes team and the occupational health team at her place of employ- ment are monitoring her diabetes status until the employer makes a decision regarding train driving for employees on insulin. This is a sensi- tive issue at the moment as no train operating company in the UK has so far allowed train driving on insulin, and understandably relates to the fit- ness to perform safety critical work alongside the concern of insulin as a ‘high-risk’ medication in terms of hypoglycaemia susceptibility. Development of occupational health guidance The ‘Guidance on Medical Fitness for Railway Safety Critical Workers’ GOGN 3655 gives general guidance on railway workers who have dia- betes.6 Taking this into account and the available literature on diabetes treated with insulin, particularly the risks of sudden incapacity due to hypoglycaemia and the concern about hypoglycaemia without warning, the following suggested approach has been developed by the authors to reflect current expert knowledge and published referenced resources.3,7–11 1. The following information is necessary before a train driver with diabetes treated with insulin is allowed to be considered for driving. • The employee, if they have type 1 diabetes, must have been stable on insulin for at least six months. • If the employee has type 2 diabetes requiring insulin, he/she should have had a stable regimen for at least three months. • In any driver taking insulin, the introduction of a new drug or class of insulin should trigger a further period of observation of up to three months for a new insulin, and two months for the addition of an oral hypoglycaemic medication. • A report should be obtained from the employee’s diabetes consultant covering the previous three years or since diagnosis, whichever is sooner, with the following information: – History of diabetes, evidence of any complications (renal, neurologi- cal, ophthalmological) and any other medical conditions. – Confirmation that the employee has adequate awareness of clinical symptoms of impending hypogly- caemia. • There should be a record of regu- lar blood sugars throughout the day (essentially by the use of a recording glucose meter with a non-deletable memory with three months’ capacity to allow review); the blood glucose target to fall between 5mmol/L and 10mmol/L for over 90% of the read- ings, and an HbA1c of less than 69mmol/mol (8.5%). • Continuous glucose monitoring should be seen as essential certainly for a baseline assessment and, in terms of ongoing usage, can be considered if supported and agreed by the treating consultant diabetologist. Device speci- fications to be determined by recom- mendation from the clinician. Figure 1. Longitudinal pattern of HbA1c over time in the example case history 80 64 48 32 16 0 Lower range Upper range Value 05/11/2009 27/10/2011 26/09/2012 24/12/2013 HbA1c(mmol/mol) 26/01/2011 20/03/2012 29/01/2013 07/04/2014 Sample received
  • 3. • A history of hypoglycaemia that resulted in a seizure, loss of conscious- ness, impaired cognitive function or required the assistance of others within the previous year, unless there is a clear reason, should make the employee unfit for train driving. • Information should be sought as to the employee’s awareness of hypogly- caemia. If the record of blood sugars shows levels of <3.5mmol/L without any symptoms, this should be a cause for concern. 2. Commencement of train driving can only be undertaken with compliance to the following restric- tions/conditions. • The employee should take his/her blood sugar at the start of a shift and every 2 hours during the shift. This should be by means of a non- deletable recording glucose meter with a three months’ memory capac- ity. It is the responsibility of the line manager to always check and estab- lish if a blood glucose diary is being maintained and to refer to occupa- tional health (OH) if the diary is not being maintained or if there is other cause for concern. If there is any lack of clarity, then a low threshold for the use of continuous glucose monitor- ing is advised. Pending an OH assess- ment, the employee is restricted from driving. • On commencing a shift, the employee should inform the line manager that he/she is fit to under- take train driving. • If at any time during the shift the employee feels hypoglycaemic or the blood glucose is found to be less than 5mmol/L on testing, he/she should stop driving and inform the line manager. • Following any feelings of hypogly- caemia, or blood glucose less than 5.0mmol/L, driving should not resume until at least 45 minutes after consuming an amount of rapidly absorbable glucose equivalent to 15g of glucose (e.g. 4 ‘Glucotabs’, which contains 4g of fast-acting glucose per tablet) and a normal blood glucose (>5mmol/L) has been recorded. For such a situation, every employee con- cerned should have an emergency supply of fast-acting glucose on his/her person or within easy reach within the driver’s cab. In addition, a slow-acting carbohydrate (10–20g) should be consumed to help maintain the blood glucose level above 5mmol/L and to prevent it from falling again, e.g. a slice of bread, a piece of fruit, a couple of digestive biscuits or a packet of crisps. • Alcohol should be avoided during the 24 hours preceding a shift. • Changes in the insulin regimen or the introduction of a new oral hypo- glycaemic agent are a period of high risk for hypoglycaemic episodes. If any changes of insulin regimen, or new hypoglycaemic agent, are pro- posed, the employee should be restricted from driving until review in OH: this is likely to lead to a period of restriction from driving for up to two to three months. • If the employee suffers a hypogly- caemic episode requiring the assis- tance of others, whether on duty or off work, he/she should stop driving pending a review in OH. • An update report should be obtained annually from the employee’s diabetes consultant. • There should be close collabora- tion between OH, the employee, the line manager and human resources (HR) so that the following responsi- bilities are clearly understood and adhered to: – The employee is responsible for his/her own health, monitoring his/her blood glucose as recom- mended by OH, reporting any adverse symptoms or hypoglycaemia to his/her line manager. – A signed agreement with each driver will be proposed to ensure each driver understands the signifi- cant commitment he/she will have to make. – The line manager is responsible to check and ensure that the blood glucose diary is being maintained for every shift and inform OH and restrict the employee from driving duties if this is not done. – The line manager should be aware of, and be able to accommo- date, the following from an opera- tional perspective: regular checks of blood sugar during each shift, breaks for snacks if necessary, the require- ment not to drive if blood sugar at any time is less than 5mmol/L or if there is evidence of hypoglycaemia. – HR managers and senior man- agement within the organisation should be fully aware of the potential impact of having drivers on insulin on operational capacity. – It is also necessary to obtain the commitment of senior management in the organisation prior to the intro- duction of this approach for drivers on insulin. Conclusions Despite disability legislation, some people with diabetes (particularly those taking insulin) still experience discrimination. If an individual is well controlled with stable capillary glu- cose values and no significant hypo- glycaemia and intact awareness then, from a medical perspective, it should be acceptable for them to undertake safety critical work. The 2010 Equality Act itself unfortunately does not make a distinction with regard to such a ‘disability’ as diabetes between someone employed in a role who subsequently goes on to develop diabetes and an individual who has pre-existing diabetes who is applying de novo to undertake such work. With regard to train driving, the situation is complex: on the one hand, it can be argued that a train driver who is well controlled on insulin should be able to drive. This needs to be balanced against the operational implications of having a train driver on insulin: arrangements need to be made to enable regular blood glu- cose measurements, as recommended above. Furthermore, the business needs to be able to cope with rare situ- ations of a driver being temporarily removed from driving duties, at short notice, in the event that the blood glu- cose is less than 5mmol/L. At a time when the railway sector is under enor- mous pressure to maintain punctual- ity, and timetables for the travelling public, and avoid cancelling trains, the potential business impact of a driver on insulin needs to be considered. Finally, there is a risk of a driver having a hypoglycaemic episode when driving on the mainline. With the safety systems in place in the driver’s cab on modern trains, the train would normally stop, and there would be no direct risk to passengers. However, the impact on business con- tinuity, and the reputational risk fol- lowing such an incident, would be considerable for the train operating company (TOC). In addition, there would be a further risk of the driver 202 PRACTICAL DIABETES VOL. 32 NO. 6 COPYRIGHT © 2015 JOHN WILEY & SONS Train driving and diabetes – keeping safety on track Practice point
  • 4. having a hypoglycaemic episode in an isolated situation (in the driver’s cab) for an extended time before any assistance (medical or otherwise) can reach him/her. The operational issues high- lighted above will need to be carefully considered by senior management in each TOC before train driving on insulin is allowed. Furthermore, to our knowledge, no TOC in the UK has yet allowed train driving on insulin. There is a risk that the first TOC to do so will face a number of applications for the train driver role from individuals who have diabetes and are on insulin: because of disabil- ity legislation, rejection will not be appropriate, leading to an increasing burden, possibly non-sustainable, on the TOC concerned.12 The UK Civil Aviation Authority has been through a similar process recently, undertaking individualised assessment of insulin treated pilots and, subject to safety and risk analysis, medical certification of fitness to fly may be approved. An operational pro- tocol requires pre-flight and hourly in-flight blood glucose monitoring, using conventional capillary test strips, with results recorded in the pilot’s log-book. CGMS measuring interstitial glucose is presently consid- ered insufficiently validated under these specific circumstances.13,14 It should be noted that this initiative currently applies to commercial multi-crew aviation, so that a co-pilot in the cockpit will be present. Modern technological approaches to diabetes management may also come in handy – when CGM systems are linked to continuous subcuta- neous insulin infusion, there is the option to include a ‘low glucose suspend’ function to enable insulin delivery to be halted when there is a marked drop in glucose levels acutely in order to avoid the occurrence of hypoglycaemia.15,16 We hope that the proposed guid- ance above forms a sound basis to help clinicians manage such patients, for individuals with diabetes to understand the need for exemplary control and to provide reassurance for TOCs, as well as act as a basis for further discussion. From a business perspective, an optimal solution would be for any decision to allow train driving on insulin to be taken jointly by all TOCs, with the support of the Railway Safety and Standards Board and the Office of Rail Regulation. Acknowledgments Many thanks to Professor Ken Shaw for advice, Josie Wilson and Sara Moore, expert Specialist Diabetes Nurses at Brighton and Sussex University Hospitals, and Megan Taylor, Occupational Health Nurse Manager. Declaration of interests There are no conflicts of interest declared. Both authors contributed equally to the production of this document. References 1. Equality Act 2010. www.legislation.gov.uk/ukpga/ 2010/15/contents [last accessed 15 March 2015]. 2. Legislative Scrutiny: Armed Forces Bill – Joint Committee on Human Rights. www.publications. parliament.uk/pa/jt201012/jtselect/jtrights/145/145 13.htm [last accessed 21 March 2015]. 3. Heller SR, Nicholson AN. Aircrew and type 1 dia- betes mellitus. Aviation Space & Environmental Medicine 2006;77:454–8. 4. Faculty of Occupational Physicians of the RCP. Guidelines for assessing fitness for blue light driving, July 2013. www.fom.ac.uk/wp-content/ uploads/FOM-Guide-re-blue-light-driving.pdf [last accessed 18 March 2015]. 5. Office of Rail Regulation. Train Driving Licences and Certificates Regulations 2010. TDLCR 2010. http://orr.gov.uk/__data/assets/pdf_file/0003/4998/ train-driving-licences-regulations-2010-guidance. pdf [last accessed 20 March 2015]. 6. Rail Safety and Standards Board Limited. Guidance on Medical Fitness for Railway Safety Critical Workers. GOGN3655 Issue 2 (June 2014). www. rgsonline.co.uk/Railway_Group_Standards/Traffic %20Operation%20and%20Management/Guid ance%20Notes/GOGN3655%20Iss%202.pdf [last accessed 19 March 2015]. 7. Graveling AJ, Frier BM. Impaired awareness of hypoglycaemia: a review. Diabetes Metab 2010; 36:S64–S74. 8. Ogundipe OO, et al. Impaired hypoglycaemia awareness and employment in people with type 1 diabetes. Occupational Med 2011;61:241–6. 9. Diabetes and Driving, Position Paper of the American Diabetes Association. Diabetes Care 2014;37(Suppl 1):S97–S103. 10. Cox DJ, et al. Type 1 diabetic drivers with and without a history of recurrent hypoglycemia- related driving mishaps: physiological and performance differences during euglycemia and the induction of hypoglycemia. Diabetes Care 2010;33:2430–5. 11. Rail Safety and Standards Board Ltd. Good Practice Guide on Rail Workers & Diabetes – Guidance for Medical Assessors. RS/506 Issue 1 Draft 1a 2007. 12. www.diabetes.org.uk/Information-for-parents/ Growing-up/Work-and-discrimination/ [last accessed 7 March 2015]. 13. Diabetes UK. Pilots with diabetes allowed to fly commercial aircraft. www.diabetes.org.uk/About_ us/News_Landing_Page/Pilots-with-diabetes- allowed-to-fly-commercial-aircraft/ [last accessed 23 March 2015]. 14. Civil Aviation Authority. UK CAA Policy for the Medical Certification of Pilots and ATCOs with Diabetes. www.caa.co.uk/docs/2499/P027-Diabetic %20Certification%20Guidance.pdf [last accessed 23 March 2015]. 15. Grant P. A new approach to diabetic control: fuzzy logic and insulin pump technology. Med Eng Phys 2007;29:824–7. 16. Wilmot E, et al. Insulin pump therapy: a practical guide to optimising glycaemic control. Pract Diabetes 2014;31:121–5a. PRACTICAL DIABETES VOL. 32 NO. 6 COPYRIGHT © 2015 JOHN WILEY & SONS 203 Train driving and diabetes – keeping safety on track Practice point l People with diabetes on insulin therapy need to be judged on an individual basis when it comes to assessing fitness to undertake safety critical work l No train operating company in the UK has as yet allowed train driving to be undertaken by individuals with diabetes – that is, those with type 1 diabetes or type 2 diabetes subsequently treated with insulin l Clear parameters for safe and stable glycaemic control, with avoidance of hypoglycaemia are key from a safety perspective Key pointsOperator-presence control A dead man’s switch is a switch that is automatically operated if the human operator becomes incapacitated, such as through death, loss of consciousness or being bodily removed from control.These switches are usually used as a form of fail-safe where they stop a machine with no operator from potentially dangerous action.They are commonly used in this manner in locomotives, lawn mowers, tractors, personal watercraft, outboard motors, and chainsaws. On some machines, these switches merely bring the machines back to a safe state, such as reducing the throttle to idle or applying brakes while leaving the machines still running and ready to resume normal operation once control is re-established.With modern railway systems, the driver is typically alone in an enclosed cab. Electrically or pneumatically linked dead-man’s controls involve relatively simple modifications of the controller handle, the device that regulates traction power. If pressure is not maintained on the controller, the train’s emergency brakes are applied and the train stops.The driver does not necessarily need to be dead for this to function