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David ewing duncan open science 7-30-10
1.
Open Science Meets
Personalized Health David Ewing Duncan Director, Center for Life Science Policy, UC Berkeley
2.
Two Great Movements
Citizen patients Citizen scientists
3.
Historical Moment
4.
People + Technology
= Empowerment
5.
“With great power
comes great responsibility...”- Ben Parker (Spiderman’s Uncle)
6.
7.
Feel it coming:
early adopters
8.
Outmoded paradigms
9.
Tired of hearing
no
10.
Bad customer service
11.
12.
Age of Personalized
Health
13.
14.
9,366 genotypes
15.
320 environmental
toxins
16.
22 hours
of MRI brain scans
17.
~ 2
liters of blood
18.
~ $150,000The
Experiment
19.
Healthy
20.
Not Just Genes...
Environment Brain Body
21.
Experimental Family Alzheimer’s
(rs4420638) Father Mother AG AA David Brother AA AG Daughter AA Heart Attack (rs1075728) Father Mother AG AG David Brother GGAA Daughter AG
22.
Favorite Genetic Marker
CYP1A2 Caffeine Fast Metabolizer
23.
Mercury and Me
24.
Mercury andMe
25.
Mercury and Me
Halibut (lunch) Swordfish (dinner)
26.
Mercury Before: 4
ppb Mercury After: 13 ppb
27.
My genetic sensitivity
to mercury(Envirogenomics)
28.
High Anxiety
29.
Fear and Anxiety
Emotional incongruence (emotional conflict) Emotional conflict resolution (emotion regulation)
30.
(Don’t) Be Still
My Beating Heart
31.
First Add Genomics
Copyright 2008 Entelos, Inc.
32.
Biomarkers (Chemistry) Copyright
2008 Entelos, Inc.
33.
Scans: Ultrasound and
CT Copyright 2008 Entelos, Inc.
34.
Genes + Environment
+ Biomarkers + Ultrasound + CT Scan Entelos Project Combine Risk Factors
35.
Prediction of my
future… ? Copyright 2008 Entelos, Inc.
36.
Lost 10 pounds
37.
38.
Skeptical public
39.
Resistance from traditional
medicine
40.
Expensive
41.
42.
The Obama Effect
43.
Discrimination
44.
Genetic thrallism (Gattaca)
45.
Unleashing monsters
46.
47.
Integration is key
48.
Get creative with
law, policy, education, ethics, media
49.
Private sector and
early adopters
50.
51.
Be proactive with
government and law enforcement
52.
Work with Big
Science – they need you, you need them
53.
54.
Still going… more
tests
55.
56.
www.ExperimentalMan.com
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