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Food additives
growth promoters:
improve the production traits of healthy animals
• Antibiotics: produces by other microorganisms, fungi that protect
the growth of bacteria
– reduce the number of pathogenic bacteria (E. coli, Salmonella
sp., etc.), prevent the infection of the digestive tract,
– increase the absorptive capacity of the small intestine (decrease
the thickness of the intestinal wall)
– reduce the competition of bacteria with the host (bacteria
ferment the nutrients before digestion)
– they have been used mainly in pig and poultry nutrition
– their widespread use could cause the ability of certain strains to
be resistant to many antibiotics
– therefore in the EU the use of antibiotic growth promoters has
been restricted since 2000
• Probiotics: live microbial food supplement
– containing mostly lactic acid producing bacteria
– by reducing the pH in the intestine, reducing the numbers of harmful
bacteria (competitive exclusion)
– enhance immune competence
– are heat sensitive (pelleting)
• Prebiotics: oligosaccharides (2-20 monosacharides) that modify the
balance of the microfloral population by promoting the growth of the
beneficial bacteria
– can be fermented by the favourable bacteria
– decreasing the attachment of harmful bacteria with the gut wall
– galactooligosaccharides (GOS) (legume seeds)
– fructooligosaccharides (FOS) (cereal grains)
– mannanoligosaccharides (MOS) (yeast cell walls)
• Symbiotics: contain both probiotics and prebiotics
• Organic acids: (lactic acid, formic acid, fumaric acid, citric acid,
propionic acid etc.)
– stabilise the intestinal microflora by decreasing the pH
– can be effective in early weaned, young animals
– incorporated into the diet (6-25 g/kg) or into the drinking water
• Enzymes:
– as a result of advances in biotechnology, more effective enzyme
preparations can be produced relatively inexpensively
– supplement the insufficient enzyme secretion of young animals
(amylase, protease, lipase etc.)
– can improve the availability of plant storage polysaccharides (starch,
oils and proteins) by degrading the cell wall content like cellulose by
the enzyme cellulase (5-10% improvement can be achieved in poultry
and pig trials)
– destroy ant-nutritive materials that interfere with the digestion and
utilisation of nutrients (glucanase, xylanase destroy cereal cell wall
compounds, β-glucans and arabinoxylans)
– phytase releases phosphorous and other minerals from phytic acid in
cereals and oilseeds (greater availability of minerals, less need for
inorganic phosphorous, beneficial effect on the environment)
• Flavory materials: (sugars, vanilla, canella etc.)
– increase the feed intake
– can be effective mostly in young intensively growing animals
– their effect depends on the flavour sensation of different animal species
Effect of β-glucanase enzyme supplementation on
the growth of broiler chicks
wheat content of the diet
control
enzyme
• Plant extracts, essential plant oils: (sage, peppermint, garlic, thyme etc.)
– can be used for the partial replacement of antibiotics
– complex effects (flavour materials, antimicrobial compounds,
antioxidants etc.)
– the products in the practice are mostly the mixture of different plant
extracts and oils
– their market share is increasing in Europe
b., other food additives
• NPN materials: (urea, ammonium salts)
can be used in ruminant animal nutrition
mostly in low milk producing cows, beef cattle
they are strict rules for using them
• Toxin binders: used for binding mycotoxins ; ochratoxin, aflatoxin etc.),
decrease their absorption
aluminium silicates (bentonit)
glucomannans (yeast cell wall extracts)
they efficiency is toxin dependent
bind also some minerals and nutrients
• crystallinene amino acids:
– L – lysine
– DL – methionine
– in the near future threonine, tryptophan and arginine will also be available in the
feed industry
–colour materials: carotenoids (zeaxanthin, lutein, licophin, capsanthin etc.)
– egg yolk
– skin, the fat below the skin
– using is synthetic colour compounds is limited in the EU
•antioxidants: protecting vitamins and fatty acids from the oxidation
– synthetic antioxidants
– etoxi-methil-quinolin (EMQ)
– butil-hidroxi-toluol (BHT)
– natural antioxidants (vit. E, vit. C, carotenes etc.)
– they need depends on the fat and unsaturated fatty acid content of the diet.

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Feed additives

  • 1. Food additives growth promoters: improve the production traits of healthy animals • Antibiotics: produces by other microorganisms, fungi that protect the growth of bacteria – reduce the number of pathogenic bacteria (E. coli, Salmonella sp., etc.), prevent the infection of the digestive tract, – increase the absorptive capacity of the small intestine (decrease the thickness of the intestinal wall) – reduce the competition of bacteria with the host (bacteria ferment the nutrients before digestion) – they have been used mainly in pig and poultry nutrition – their widespread use could cause the ability of certain strains to be resistant to many antibiotics – therefore in the EU the use of antibiotic growth promoters has been restricted since 2000
  • 2. • Probiotics: live microbial food supplement – containing mostly lactic acid producing bacteria – by reducing the pH in the intestine, reducing the numbers of harmful bacteria (competitive exclusion) – enhance immune competence – are heat sensitive (pelleting)
  • 3. • Prebiotics: oligosaccharides (2-20 monosacharides) that modify the balance of the microfloral population by promoting the growth of the beneficial bacteria – can be fermented by the favourable bacteria – decreasing the attachment of harmful bacteria with the gut wall – galactooligosaccharides (GOS) (legume seeds) – fructooligosaccharides (FOS) (cereal grains) – mannanoligosaccharides (MOS) (yeast cell walls) • Symbiotics: contain both probiotics and prebiotics • Organic acids: (lactic acid, formic acid, fumaric acid, citric acid, propionic acid etc.) – stabilise the intestinal microflora by decreasing the pH – can be effective in early weaned, young animals – incorporated into the diet (6-25 g/kg) or into the drinking water
  • 4. • Enzymes: – as a result of advances in biotechnology, more effective enzyme preparations can be produced relatively inexpensively – supplement the insufficient enzyme secretion of young animals (amylase, protease, lipase etc.) – can improve the availability of plant storage polysaccharides (starch, oils and proteins) by degrading the cell wall content like cellulose by the enzyme cellulase (5-10% improvement can be achieved in poultry and pig trials) – destroy ant-nutritive materials that interfere with the digestion and utilisation of nutrients (glucanase, xylanase destroy cereal cell wall compounds, β-glucans and arabinoxylans) – phytase releases phosphorous and other minerals from phytic acid in cereals and oilseeds (greater availability of minerals, less need for inorganic phosphorous, beneficial effect on the environment) • Flavory materials: (sugars, vanilla, canella etc.) – increase the feed intake – can be effective mostly in young intensively growing animals – their effect depends on the flavour sensation of different animal species
  • 5. Effect of β-glucanase enzyme supplementation on the growth of broiler chicks wheat content of the diet control enzyme
  • 6. • Plant extracts, essential plant oils: (sage, peppermint, garlic, thyme etc.) – can be used for the partial replacement of antibiotics – complex effects (flavour materials, antimicrobial compounds, antioxidants etc.) – the products in the practice are mostly the mixture of different plant extracts and oils – their market share is increasing in Europe b., other food additives • NPN materials: (urea, ammonium salts) can be used in ruminant animal nutrition mostly in low milk producing cows, beef cattle they are strict rules for using them • Toxin binders: used for binding mycotoxins ; ochratoxin, aflatoxin etc.), decrease their absorption aluminium silicates (bentonit) glucomannans (yeast cell wall extracts) they efficiency is toxin dependent bind also some minerals and nutrients
  • 7. • crystallinene amino acids: – L – lysine – DL – methionine – in the near future threonine, tryptophan and arginine will also be available in the feed industry –colour materials: carotenoids (zeaxanthin, lutein, licophin, capsanthin etc.) – egg yolk – skin, the fat below the skin – using is synthetic colour compounds is limited in the EU •antioxidants: protecting vitamins and fatty acids from the oxidation – synthetic antioxidants – etoxi-methil-quinolin (EMQ) – butil-hidroxi-toluol (BHT) – natural antioxidants (vit. E, vit. C, carotenes etc.) – they need depends on the fat and unsaturated fatty acid content of the diet.