This presentation discusses results from the EPEMED and The Office of Health Economics (OHE) White Paper “The value of knowing and knowing the value: improving health technology assessment of complementary diagnostics”. There is a need to acknowledge new elements of value for improving health sector performance given the lack of attention in current applied health technology assessment (HTA) practices to measuring, among other things, the value of knowing (or the greater certainty of benefit) delivered by diagnostics. Author(s) and affiliation(s): Bernarda Zamora, Office of Health Economics. Conference/meeting: Second European Alliance for Personalised Medicine Congress. Location: Milan, Italy. Date: 26/11/2018

2. Diagnostic/Medical Devices Track
Value of Diagnostic Information (VODI)
from Concept to Reality
Socio-economic aspects of
Value of Knowing
Bernarda Zamora
Office of Health Economics

3. Motivation
Concern that traditional health technology
assessment (HTA) does not appropriately
recognize or reward the value of diagnostics
Need to broaden the concept of diagnostics
beyond companion diagnostics:
“Complementary diagnostics”
Diagnostics provide value to patients beyond
health gain and cost-saving: they can reduce
uncertainty about benefit:
“Value of knowing”

4. OHE/EPEMED White Paper
To identify key issues facing the HTA
of complementary diagnostics in
Europe
To provide coherent and consistent
terminology for the definition of
diagnostics and the elements of value
To define options for addressing
challenges and barriers
To recommend approaches for dealing with them

5. Definition of Complementary
Diagnostics

7. Steps towards implementation
ISPOR Initiative on US Value
Assessment Frameworks

8. ISPOR Initiative on US Value
Assessment Frameworks
Recommendation 3.1: Apply cost-
effectiveness analysis to inform public
and private coverage and
reimbursement decision making
Recommendation 3.2: Support additional
research that enhances the
applicability, scope, and relevance of
cost-effectiveness analysis for decision
making

9. CONCLUSIONS
Application of Extended CEA

10. Thank you
Email: bzamora@ohe.org
Website: www.ohe.org • Blog: http://news.ohe.org/