1. Schizophrenia Ni dheesha T 1 st year msc nursing Nursing college kottayam

9. Positive and Negative Symptoms Negative Positive Alogia Hallucinations Affective flattening Delusions Avolition-apathy Bizarre behaviour Anhedonia-asociality Positive formal thought disorder Attentional impairment

13. Grossly disorganized behavior . Difficulty in goal directed behavior (ADLs), unpredictable agitation or silliness, social disinhibition, or bizarre behavior. There is a purposelessness to behavior.

24. COND C] hallucinated voices, commenting permanently the behavior of the patient or they talk about him between themselves, or the other types of hallucinatory voices, coming from different parts of body. D] permanent delusions of different kind, which are inappropriate and unacceptable in given culture

46. Genes x Environment Behavior Emotion Cognition Perception Development

47. Schizophrenia susceptibility genes: Current candidates Whole genome linkage 1q,2p,5q,6p,6q,8p,10p,11q,13q,15q,22q Finer mapping SNP association dysbindin (6p) ( seven )* neuregulin (8p) ( six)* G72 (13q) ( three )* MRDS1 (6p) ( four )* Functional candidates COMT (22q) ( eight )* GRM3 (7q) ( four )* GAD 1 (2q) ( four )* CNRNA7 (15q) ( two )* PPP3CC (8p) ( two )* Akt1 (two) Chromosomal translocation DISC1 (1q) ( three )* PRODH (22q) (two ) Expression profiling RGS4 (1q) ( four )* * Number of positive samples worldwide

56. Mental disorders are brain disorders: Loss of gray matter in childhood schizophrenia

62. Psychotherapy - an adjunct to meds and is very useful to keep the patient on the meds. Group therapy Family therapy Community support groups Treatments