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INTRODUCTION TO MED  (PSYCHIATRY)    SCHIZOPHRENIA AND OTHER PSYCHOTIC DISORDERS
SCHIZOPHRENIA ,[object Object]
SCHIZOPHRENIA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
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Five Types of Schizophrenia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
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Physiologic Abnormalities ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Mimics of Schizophrenia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Epidemiology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Classification Agent (Duration) Dose (mg/day) Clinical use Traditional  Low - potency Thioridazine (Mellaril)  200 -600 Depression with intense anxiety or agitation Chlorpromazine(Thorazine) 100 – 800 To treat nausea and vomiting Hiccups  Traditional High - potency Haloperidol (Haldol) 2 – 15 Psychosis secondary to organic syndrome; Tourette disorder Perphenazine (Trilafon)  8 – 40 To treat nausea and vomiting Pimozide (Orap) 1 –10 Tourette disorder, body dysmorphic disorder Trifluoperazine (Stelazine) 4 – 20  Non-psychotic anxiety (up to 12 weeks)
Classification Agent (Duration) Dose (mg/day) Clinical use Atypical  Anti-psychotics Clozapine (Clozaril) 300 – 900 Effective for negative, chronic, and refractory symptoms Risperidone (Risperdal) 4 – 8 Useful for negative symptoms; has few side effects Olanzapine (Zyprexa) 10 – 20 Useful for negative symptoms; has few side effects
Side Effects of Anti-Psychotics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
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Prognosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Other Psychotic Disorders ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Brief Psychotic Disorder ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
Typical Patient Presentation ,[object Object]
Treatment  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Schizophreniform Disorder ,[object Object],[object Object],[object Object],[object Object]
Typical Patient Presentation ,[object Object]
Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Schizoaffective Disorder ,[object Object],[object Object],[object Object]
Typical Patient Presentation ,[object Object]
Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Delusional Disorder ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object]
Typical Patient Presentation ,[object Object]
Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Shared Psychotic Disorder ,[object Object],[object Object],[object Object],[object Object]
Typical Patient Presentation ,[object Object]
Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object]
Lecture 4 Schizophrenia Disorders

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Lecture 4 Schizophrenia Disorders

  • 1. INTRODUCTION TO MED (PSYCHIATRY) SCHIZOPHRENIA AND OTHER PSYCHOTIC DISORDERS
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  • 18. Classification Agent (Duration) Dose (mg/day) Clinical use Traditional Low - potency Thioridazine (Mellaril) 200 -600 Depression with intense anxiety or agitation Chlorpromazine(Thorazine) 100 – 800 To treat nausea and vomiting Hiccups Traditional High - potency Haloperidol (Haldol) 2 – 15 Psychosis secondary to organic syndrome; Tourette disorder Perphenazine (Trilafon) 8 – 40 To treat nausea and vomiting Pimozide (Orap) 1 –10 Tourette disorder, body dysmorphic disorder Trifluoperazine (Stelazine) 4 – 20 Non-psychotic anxiety (up to 12 weeks)
  • 19. Classification Agent (Duration) Dose (mg/day) Clinical use Atypical Anti-psychotics Clozapine (Clozaril) 300 – 900 Effective for negative, chronic, and refractory symptoms Risperidone (Risperdal) 4 – 8 Useful for negative symptoms; has few side effects Olanzapine (Zyprexa) 10 – 20 Useful for negative symptoms; has few side effects
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