Hematology Rivas2008 Lecture1

Hematology - Oncology Introduction to Hematology Antonio Rivas PA-C January 2009

Objectives ,[object Object],[object Object],[object Object],[object Object],[object Object]

Hematology : • From the Greek, haima-blood and logos discourse Hematology is the study of the blood and its main constituents: plasma and cells • Blood accounts for 7-8% of total body weight in an average 70kg adult • Total volume of blood is about 5-6L • The plasma is the fluid portion of the blood: 90% water and 10% proteins: Albumin,Globulins, and Fibrinogen • The formed elements are: the red blood cells, the white blood cells and the platelets.

Hematology-Albumin ,[object Object],[object Object],[object Object]

Hematology - Globulins ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Hematology - Fibrinogen ,[object Object],[object Object]

Functions of the blood ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Hematopoiesis: ,[object Object],[object Object],[object Object],[object Object],[object Object]

Hematopoiesis ,[object Object],[object Object],[object Object],[object Object]

Ontogeny: ,[object Object],[object Object],[object Object],[object Object],[object Object]

Pluripotent Stem cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Regulation of Hematopoiesis ,[object Object],[object Object],[object Object]

Cytokines and their activities. ,[object Object],[object Object],[object Object],[object Object]

Hematopoietic Differentiation Pathway

[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Myeloid lineage-Erythrocytes ,[object Object],[object Object],[object Object],[object Object],[object Object]

Erythrocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Erythropoiesis ,[object Object],[object Object],[object Object]

Erythrocyte maturation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Hemoglobin ,[object Object],[object Object],[object Object],[object Object],[object Object]

Hemoglobin-Iron cycle ,[object Object],[object Object],[object Object],[object Object],[object Object]

Iron cycle ,[object Object],[object Object],[object Object],[object Object]

Erythrocyte destruction ,[object Object],[object Object],[object Object],[object Object]

Leukocytes - WBCs ,[object Object],[object Object],[object Object]

Granulocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Granulocytes origin and maturation ,[object Object],[object Object],[object Object]

Neutrophils ,[object Object],[object Object],[object Object],[object Object],[object Object]

Neutrophils ,[object Object],[object Object],[object Object],[object Object]

Neutrophils ,[object Object],[object Object]

Neutrophils ,[object Object],[object Object],[object Object]

Neutropenia <1800/mm 3 or <1.8 × 10 9 /L ,[object Object],[object Object]

Eosinophils ,[object Object],[object Object],[object Object],[object Object],[object Object]

Eosinophils ,[object Object],[object Object]

Eosinophils ,[object Object],[object Object],[object Object],[object Object]

Eosinophilia (increased circulating eosinophils) > 5% or > 500 cells/mm 3 or > 0.5 × 10 9 /L ,[object Object],[object Object],[object Object],[object Object]

Basophils ,[object Object],[object Object],[object Object],[object Object],[object Object]

Monocytes/Macrophages ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Monocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Thrombocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Lymphocytes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Lymphocytes ,[object Object],[object Object],[object Object],[object Object]

B-Lymphocytes ,[object Object],[object Object],[object Object]

T-Lymphocytes ,[object Object],[object Object],[object Object],[object Object]

T- Helper / Suppressor ,[object Object],[object Object],[object Object],[object Object],[object Object]

Laboratory tests ,[object Object],[object Object],[object Object]

Complete Blood Count ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

WBC count ,[object Object],[object Object],[object Object],[object Object]

Leukocytosis ,[object Object],[object Object],[object Object],[object Object]

Leukocytosis ,[object Object],[object Object]

Other causes of leukocytosis ,[object Object],[object Object],[object Object],[object Object],[object Object]

Leukocytosis and no evidence of clinical disease ,[object Object],[object Object],[object Object]

Steroid therapy modifies the leukocyte response ,[object Object],[object Object]

Leukopenia: WBC < 4000/mm 3 or < 4.0 × 10 3 /mm 3 or < 4.0 cells × 10 9 /L ,[object Object],[object Object],[object Object]

Leukopenia ,[object Object],[object Object],[object Object],[object Object]

Differential White Blood Cell Count (Diff; Differential Leukocyte Count) ,[object Object],[object Object]

Differential White Blood Cell Count (Diff; Differential Leukocyte Count) ,[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object]

Differential White Blood Cell Count (Diff; Differential Leukocyte Count) ,[object Object],[object Object],[object Object]

Total RBC count ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Total RBC count ,[object Object],[object Object],[object Object]

Hemoglobin ,[object Object],[object Object],[object Object]

Hematocrit ,[object Object],[object Object],[object Object],[object Object]

Platelet count ,[object Object],[object Object],[object Object]

Red blood cell indices ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

RBCs indices ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

RBCs indices ,[object Object],[object Object],[object Object]

RBCS morphology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

RBCs morphology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

RBC morphology ,[object Object],[object Object],[object Object]

NRBC, and Basophilic Sttipling

Hematology Rivas2008 Lecture1

Empfohlen

Empfohlen

Weitere ähnliche Inhalte

Was ist angesagt?

Was ist angesagt? (20)

Andere mochten auch

Andere mochten auch (20)

Ähnlich wie Hematology Rivas2008 Lecture1

Ähnlich wie Hematology Rivas2008 Lecture1 (20)

Mehr von Miami Dade

Mehr von Miami Dade (20)

Kürzlich hochgeladen

Kürzlich hochgeladen (20)

Hematology Rivas2008 Lecture1