02 perreul relu 13 avril soir

How to manage PCV2 in gilts? Dr Jean-Bernard HERIN, Avian and Swine technical and marketing manager Dr Guillaume PERREUL, Swine technical manager

Agenda ,[object Object],[object Object],[object Object],[object Object],[object Object]

Material and methods ,[object Object],[object Object],[object Object],[object Object],[object Object]

ELISA PCV2 SYNBIOTICS and interpretation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Forum d’Athènes

ELISA PCV2 SYNBIOTICS: What kind of applications? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Forum d’Athènes

Results: company A 125 102 141 42 52 62 SD (%) 3163 4673 1624 11144 240 2077 PCV2 ELISA titre A6 A5 A4 A3 A2 A1 Farm

Results : company P 84 66 59 146 34 78 100 73 191 123 SD (%) 3145 6592 2429 1014 300 1216 100 1712 585 840 PCV2 ELISA titre P10 P9 P8 P7 P6 P5 P4 P3 P2 P1 Farm

Results: company C 138 139 63 65 66 188 114 144 SD (%) 1022 4457 3003 8949 6592 349 11 327 PCV2 ELISA titre C8 C7 C6 C5 C4 C3 C2 C1 Farm

Results: company D 0 88 104 94 187 SD (%) 15000 48 54 2611 3455 PCV2 ELISA titre D6 D5 D3 D2 D1 Farm

Low and heterogeneous titers: which consequences? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

* 3 fœtuses aborted before necropsy Sow 25 : the lowest titer and the biggest pcv2 contamination in genital tract 1/10 4 1/10 4 1/10 3 1/10 3 1/10 4 1/10 4 1/10 3 1/10 3 1/10 2 - - - - - - - - 1 Foetus and corresponding uterine tract (right) - - - + - - - - 7 Foetus and corresponding uterine tract (left) - - - - - - - 1/11 - Amniotic fluids (positive/total litter) - - - - - - 3/7 - 10/16 Foetuses (positive/total litter) - - - - + - - - - Cervix - - - / - / - - + Tracheo-bronchial lymph node - - - - - + - - + Uterine right lymph node - - - - - - - - + Uterine left lymph node - - - - - + - - - Tonsil - - - - 28 7 21 - 21 - 35 PCR PCV2 in blood at D+AI 8 0* 11 0 0 0 7 11 16 Pregnant : YES Pregnant : NO Pregnant : YES Négative sows Infected sows

[object Object],[object Object],[object Object],Pr Hans NAUWYNCK DVM, PhD – Laboratory of Virology – Faculty of Veterinary Medicine – Ghent University - Belgium What should we do?

Vaccination study with Circovac at the experimental station of Guernevez Impact on acclimatization and performances of high health status gilts

[object Object],[object Object],[object Object],Gilt health status in quarantine

Material and methods ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],A B

Results: clinical monitoring in quarantine ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Non vaccinated Nothing Nothing Nothing Nothing Dia (1) Nothing Nothing Nothing 15 B 30 Nothing Anor (1) Nothing Nothing Nothing Nothing Anor (2) Nothing 15 B 29 ND ND ND Nothing Nothing Nothing Nothing Anor (1) 16 B 27 Nothing Anor (1) Nothing Nothing Nothing Nothing Nothing Nothing 18 B 26 Vaccinated 17 20 19 18 18 N Appe (1) Anor (2) Loss of weight Appe (1) Nothing Nothing Appe (2) Anor (3) B 24 Nothing Anor (4) Anor (1) Death (1) Anor (1) Nothing Appe (1) Anor (1) Appe (1) Death (1) H++ (1) Appe (1) B 23 Nothing Nothing Nothing Appe (1) Death (1) Nothing Anor (1) Appe (1) Nothing B 22 Appe (2) Anor (1) Appe (1) 5 Appe (2) Diar (2) Limp (1) 4 Appe (1) Nothing 2 Appe (1) Limp (3) Appe (1) Anor (2) 1 Appe(2) Appe (2) Diar (3) Appe (2) Appe (1) Anor (2) B 21 Anor (1) Anor (2) Nothing Appe (3) Anor (1) B 20 7 6 3 0 Week Less clinical signs in quarantine in the vaccinated batches!

Results: ADWG in quarantine Non vaccinated ≈ 325 g/d Vaccinated ≈ 439 g/d p < 0,001 Improvement of ADWG of vaccinated gilts!

ADWG 3 weeks after insemination g/day Better acclimatization of gilts at entry in farm

Results: weight at the first farrowing Weight (kg) Vaccinated Non vaccinated p < 0,05 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Total born piglets at 1 st farrowing Non vaccinated Vaccinated +0.5 total born in vaccinated group

Conclusion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Improvement all along the gilt life!

Improvement of reproductive parameters of gilts after Circovac vaccination Michel Noirrit DVM - France

Farm description ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Case description ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

PCV2 Circovac vaccination ,[object Object],[object Object],[object Object],[object Object],[object Object]

Reproductive parameters before and after Circovac Non vaccinated gilts Circovac vaccinated gilts p Gilts (number) 165 165 % return to oestrus 5.1 % 1.8 % 0.125 % abortion (n°) 7.3% (12) 3.6% (6) 0.146 % farrowing 83.9 % 90.5 % 0.072 Mummies/litter 0.3 0.3 Stillborn/litter 0.8 0.8 Weaning to Fecundation interval 8.7 days 5.5 days NA

Conception rate of young sows and immunity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],PCV2 vaccination seems necessary even without clinical signs of PMWS

PORFIMAD study ,[object Object],[object Object],[object Object],[object Object],[object Object],28x10 6 /year 18x10 6 /year 0,9x10 6 /year 1,2 10 6 800x10 3 44x10 3

Total born/litter Born alive/litter Vaccinated Non vaccinated + 0,5 Parity + 0,4 Parity

Conclusion ,[object Object],[object Object],[object Object],[object Object],[object Object]

Discussion ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

02 perreul relu 13 avril soir

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