10. introduction
Without an adequate vascular access, HD efficiency is
reduced, which results in increased morbidity and
mortality
Dialysis access is most common vascular surgery
procedure
Access-related problems are responsible for 50% of the
hospitalizations of HD patients
11. introduction
Short-term catheters should be used for acute dialysis and for a
limited duration in hospitalized patients.
Non cuffed femoral catheters should be used in bed-bound patients
only.
Long-term catheters should be used in conjunction with a plan for
permanent access. Catheters capable of rapid flow rates are
preferred.
Catheter choice should be based on local experience, goals for use,
and cost.
Long-term catheters should not be placed on the same side as a
maturing AV access, if possible (RT sided for RT handed).
12. Introduction
Patients with advanced CKD disease stage 4
CKD (GFR <30), or based on progression of
renal disease) who have elected hemodialysis
as their choice of renal replacement therapy
should be referred to an access surgeon in
order to evaluate and plan construction of AV
access
If a prosthetic access is to be constructed, this
should be delayed until just before the need for
dialysis.
13. Were it possible to design the ideal catheter, it might
include the following features
Able to deliver high flow (>400 ml/min)
reliably
Easy to insert and remove
Comfortable and acceptable by patient
Durable
Free of infection
Does not cause venous thrombosis or stenosis
Free of fibrin sheath
Inexpensive
16. Advantages
Universally applicable
Multiple access sites
No maturation time can be used
immediately
No direct hemodynamic effects on the
circulation
Allows time for maturation of native AVF
Thrombotic complications simple to correct
17. disadvantages
The shortest long term patency rates of all
permanent access procedures
Lower blood flow rates obligating longer dialysis
times
External device
Morbidity
Insertion complications
Thrombosis
Infection
> 3 months -morbidity excessive
Risk of central vein stenosis or occlusion
•Limits chronic access options
18. recommendation
These catheters are suitable for immediate use
and should not be inserted before needed .
The subclavian insertion site should not be used
in a patient who may need permanent vascular
access .
19.
20. Alternative placement sites
2nd
left internal jugular
-Higher incidence of flow problems
-Higher risk of stenosis
3rd
inferior vena cava
-Femoral –best alternative
-Translumbar
Subclavian
-High risk of stenosis
-Acceptable only if no further arm access
planned
21. Chest x-ray is mandatory after subclavian and
internal jugular insertion prior to catheter use to
confirm catheter tip position
Femoral catheters should be at least 19-cm long to
minimize recirculation.
Noncuffed femoral catheters should not be left in
place longer than 5 days and should be left in
place only in bed-bound patients.
22.
23.
24.
25.
26.
27.
28.
29. Optimal Tunneled Hemodialysis catheter
Place in right internal jugular
Use ultrasound for cannulation
Use fluroscopy for placement
Place tip well within atrium
30. The primary determinants of catheter blood flow
(1) are catheter (inner) size dimensions
(2) Tip placement
31. Tip position:
Blind placement of a relatively stiff device
through the right internal jugular vein has
created the necessity of using a short catheter to
avoid atrial perforation.
The tip of these catheters comes to be
located in the proximal part of superior vena
cava, and this tip location in smaller blood
vessels does not allow for as great a blood
flow as catheters located in the distal
superior vena cava and the right atrium
32. Catheter length:
NKF-DOQI guidelines recommend placement of a catheter
with the tip adjusted to the level of the caval atrial junction
or into the right atrium to ensure optimal blood flow.
For untunneled catheters, the catheter length and diameter
should be adjusted to the size of the patient.
33. A table was made to help with the selection of the
total catheter length and diameter in relation to the body surface
area and insertion site.
In general, in patients with a body surface
area of 1.5 to 2.0 m2
-A 12-15 cm catheter should be selected for
the jugular vein in the low right position and
-A 15-19 cm catheter for the left jugular
vein.
-A 14 to 17 cm catheter should be used for
the right subclavian vein and
A17 to 22 cm catheter for the left subclavian
vein.
34. Patient comfort
Subclavian catheters are more comfortable for the patient
and provide reliable blood flow if placed in the right atrial
cavity( SVC ostum)
It was shown that in the US 46% of all temporary catheters
used in patients starting hemodialysis treatment were
inserted into the subclavian vein.(may be lower infection)
(against DOQI guidelines)
35.
36. Recirculation
Recirculation:
With the use of catheters, recirculation is
dependent upon two factors:
the location of the catheter tip
the status of the patient's central circulation.
47. Nonfunctional non cuffed catheters can be
exchanged over a guide wire as long as the exit
site and tunnel are not infected.
Exit site, tunnel tract, or systemic infections
should prompt the removal of non cuffed
catheters.
48. The Problem is that we
forget that these
catheters are in the
heart exactly like our
patients who think that
these catheter are in the
neck or chest .
49. After decades of success in dialysis research and
treatment, prompt availability of a well-functioning
vascular access for dialysis remains a disturbing problem.
(Ravani P et al. Am J Kidney Dis 2002; 40:1264-76)
65. Outflow assessment
Arm elevation test
• when the extremity is elevated , the
fistula collapses completely if there is no
outflow obstruction.
• when the extremity is elevated , the
portion of the fistula distal to point of
stenosis remains distended, while the
proximal portion collapses in the normal
fashion.
66. Palpation (Feel(
-Palpation of the thrill along the course of the vein
Assessment of the inflow of the blood
Assessment of the accessory veins
70. Complications of fistulae and
grafts
Clotted: No thrill = thrombosis . seek immediate medical opinion. Swift
intervention (within 48h) either via interventional radiology (local
thrombolysis), or surgery, may be able to salvage the fistula. The longer the
time to intervention, the less likely it is to be successful. There is no clear
evidence for anticoagulation use.
• Infection: fistulae rarely become infected beyond a superficial cellulitis.
PTFE infection is not uncommon. May be occult, causing weight loss, ESA
resistance, and failure to thrive. Antimicrobials rarely successful, and
management usually involves surgical removal.
• Aneurysm or pseudoaneurysm formation: may occur at needling sites,
especially if sites not rotated. Surgery may be necessary.
• Bleeding from an infected or aneurysmal AVF or graft is a much feared
complication (proceeds under arterial pressure!).
71. Distal ischaemia or steal syndrome: flow through the fistula
or graft may compromise distal blood supply. Cold or numb
peripheries are common but may l infarction or ischaemic pain.
Other features include paraesthesia, cyanosis, loss of distal
pulses. Patients often elect to wear a glove on the affected hand.
AVF ligation or graft removal may be necessary in severe cases.
• Excess flow
• Extravasation: blood leakage into the soft tissues. Can cause
rapid limb swelling, haemodynamic compromise, compartment
syndromes, s infection, access thrombosis.
106. Failure To Mature (FTM(
Incidence: 28 – 53%
Fistula failure can be
divided into
Early: within 1st
3 months of usage.
Late: after 1st
3 months of successful usage.
107. Risk Factors
Pre operative mapping: decrease rate of FTM.
Very small arteries & veins: less than 1.6 mm lead to
increase rate of FTM.
Functional ability of the arteries & veins to dilate.
Age > 65 years, DM, female gender & BMI > 27 increase
rate of FTM.
108. Causes of AVF early failure
Inflow problems:
Poor arterial inflow
Juxta anastomotic venous stenosis (JAVS(
Outflow problems: failure of arterializations of the
vein & presence of large & / or multiple accessory veins.
Technical factors at the time of the surgery e.g. deep
fistula difficult cannulation.
109.
110. Identification & Management
Of Early AVF Failure
Identification of patient who are at risk of early AVF failure is
critical to perform timely intervention.
Physical examination of the AV access is easy & inexpensive.
111. Specific Interventions
angioplasty: percutaneous transluminal angioplasty (PTA) is
indicated when there is > 50% stenosis of the AVF
Accessory vein ligation:
Superficial accessory vein Percutanaous ligation
Deep accessory vein coil insertion
Sequential dilatation: in cases of early failure in a long
segment of the vein which is narrowed or stenosed.
112. Specific Interventions
Surgical techniques:
Patch angioplasty.
Combination of fistula & graft (gaftula(.
New anatomists of (JAVS(.
Superficialization procedures.
Stents in AV access indicated in:
<30%residual stenosis after PTA.
Recurrent stenosis with in 3 months.
Vessel rupture during angioplasty.
Patient not suitable for surgery.
Thrombectomy:
Use of heparin is typically indicated.
Treatment should include detection of the underling anatomic
abnormality, evaluation & management of the out flow including the
central veins.
113.
114. Take Home Message
Evaluation of newly created AVF with in 1st
4-6 weeks to identify early AVF
failure.
Physical examination is simple but efficient.
Once failure identified should be referred to interventionalist for evaluation
& proper intervention.
Delay in intervention lead to:
increase no of tunneled dialysis catheters & its complications.
Risk of thrombosis & permanent loss of access.