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Who Are We?
A fully credentialed manufacturer of high
performance skin care products and
health benefiting supplements

We offer a stock line of low minimum
products (6 units per product)

Our products are labeled and branded
using our clients name

We use medical grade, high potency
ingredients formulated at very high
concentrations
What We Do?

 We provide innovative high end skin care
 products and nutritional supplements to:
 Skin Care
     Physicians-Plastic Surgeons, Dermatologists
     Naturopaths
     High-End Spas
     Destination and Resort Spas
     Medi-Spas
  Supplements
     Physicians
     Naturopaths
     Chiropractors
     Sports Stores
     Gyms
     Supplement Stores
What We Do?
 Provide a science based approach to formulation
 using experienced chemists and physicians

 We search world wide to source the most powerful
 and effective ingredients. France, Switzerland,
 Germany, Italy, Australia and many more

 We use breakthrough innovative ingredients that
 are considered best in their class

 We provide the most powerful ingredients
 available, and they are formulated in higher than
 expected concentrations

 We offer a convergence of science, advanced
 engineering, and highly responsive ingredients
95-99% Of Our Ingredients Are Actives
What We Do?
Our products benefit all age groups and skin types but our focus is:



                                             oxidative
                                           stress

                    and                                                 visual
                   elastin                                             beauty




       wrinkle                      Anti-Aging
       reduction
What We Do? The Skin Care Company?

 We stimulate the skin for rapid and dramatic
 improvements in its appearance
 Dramatically improve the appearance of:
   fine lines and wrinkles
   reduce the appearance of age spots
   discolorations
   improve skin elasticity and collagen
   production
   improve texture
   reduce puffiness
   improve skin hydration and tone
What We Do?

 Our anti-aging products are designed to
 produce extraordinary results
 Designed to be at the head of the most
 impressive class of skin care products
 Nothing currently on the market comes close
 to matching their effectiveness


   that are formulated at very high concentrations
   specifically designed to work synergistically
   designed to be highly bio-available and
   penetrate deeply
What We Do?
 Scientific team of chemists, physicians, para-
 medical aestheticians and other healthcare
 professionals

 State of the art ingredient technology

 High levels of bio-actives

 Molecular engineering

 Process engineering
Credentialed Manufacturing

 State of the Art manufacturing facility with an:
   In-house analytical & formulation laboratory
   Separate enclosed production clean rooms
   Ambient clean air system
   Water purification and monitoring systems
   Vendor certification program
   Ingredient authentication
   Global sourcing
   cGMP Certified
   NSF Certified
   FDA Audited
Owned By Healthcare Professionals
         Dr. Angela DeRosa DO, MPH, CPE,(Chief Medical and
         Compliance Officer), board certified Internist specialized in

         two AZ medical schools, past senior medical director for P&G
         Pharmaceuticals.

         Mirijana Potocnjak, (Chief Scientist and Operations Officer) is a
         biologist/chemist with 13 years of nutraceutical and skin care
         product development experience. Extensive background in
         herbs, botanicals, and organic ingredients. She is the primary
         formulating chemist for our products.

         Judy Curran RN, (Chief Executive and Marketing Officer)
         educated both as a Registered Nurse and in Business, has over
         30 years experience in domestic and international business and
         product development within the health and beauty industry.
         Clinical experience in Burns, Wound Care, and Skin Care.
Stock Product Line

SKIN CARE PRODUCTS                 SUPPLEMENT PRODUCTS


 PEPTIDE ANTI-AGING SERUM -1oz       THERMOGENIC APPETITE
 STEM CELL SERUM ! oz                SUPPRESSANT
 TIGHTENING SERUM 1 oz               WEIGHT LOSS CARBOHYDRATE
                                     CONTROL
 PEPTIDE EYE SERUM - ! oz
                                      WEIGHT LOSS FAT BURNER
 EYE LASH LENGTHENER
                                     (LIPOTROPIC)
 LIGHTENING SERUM 1 oz
                                     NATURAL HAPPINESS
 CELLULITE CREAM 5 oz
                                     LIVER SUPPORT
 FACIAL/BODY HAIR INHIBITOR 1 oz
                                     MENOPAUSE SYMPTOM RELIEF
                                     JOINT SUPPORT
                                     MUSCLE CRAMP OIL
                                     Q IMMUNE
Biology, Peptides And Serums
Understanding The Basics Of Our Formulas
Why We Use Serums As Our
Product Base?
Cosmetic serums are highly
concentrated skin treatment products

Ingredients in serums are generally
10 times more concentrated and
biologically active than in creams

Serums use powerful targeted
ingredients of small molecular sizes in
order to penetrate deeper and more
quickly than creams

Serums are considered the primary
vehicle to deliver supercharged
ingredients
Example Of Peptide Serum Results


                        Week 3
               Day 0




               Week 1
Understanding Serums

 Serums do not clog pores

 Serums are generally selected to achieve a
 very focused result such as wrinkle reductions

 They generally offer a single or limited action
 verses other products which use more
 ingredients at lower concentrations to try to
 tackle a large number of actions

 Serums are designed to penetrate and not act
 as a moisturizing barrier therefore, clients with
 dry skin should apply a moisturizing layer after
 the serums have absorbed
Improvement Using Plant Stem Cells

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Serums
Serums often seem miraculous because
they show some of their beneficial results
almost immediately and the visible
changes can be very dramatic

Serums can be used by any age client
from teen to adult

Serums can be matched to various skin
types and conditions through ingredient
selection
Serums vs Moisturizers

 Moisturizers use ingredients with larger molecular

 lipids topically and create a moisture barrier

 Moisturizers leave a fine film on the surface of the
 skin whereas serums deliver their ingredients deeper
 into the tissue

 Serums use more active ingredients which are
 targeted to change the characteristics of the skin

 Once our serums have been absorbed a moisturizer
 can be applied if needed
Ingredient Categories

 Natural Earth Harvested Ingredients
 Natural Lab Constructed Ingredients
 Lab Synthesized Synthetic Ingredients
 Animal Derived Ingredients
 Bases For Creams And Serums
 Delivery Systems
 Active vs Inactive Ingredients
 Preservatives
Natural Earth Harvested Ingredients
Natural earth harvested ingredients include:
  Standardized botanicals, organics and wild crafted
  botanicals
  Extracts, Essential Oils, Purees
  Herbs
  Minerals

  Ingredients in their naturally harvested state are often not
  well absorbed topically due to large molecular sizes and
  may not be concentrated or specific enough to produce
  noticeable positive results on the skin

  It is difficult to formulate sophisticated 100% organic
  products that can achieve our performance goals, but the
  use of some organic ingredients can be a marketing
  advantage
Natural Lab Constructed Ingredients

 Natural lab constructed ingredients are copied
 in the lab, on a molecular level, to mirror nature

 Organic chemists build identical molecular
 replicas of earth-natural ingredients except that
 they screened and designed to focus on a
 particular function which will yield the targeted
 results we are seeking

 This includes many peptides, other amino
 acids, vitamins, some anti-oxidants etc.

 Most of our ingredients fit this category
Peptide Synthesis Methodology
 Generally a biomedical researcher will
 explore the possibility of increasing the
 native    potency      or    performance
 characteristics of a given substance,
 such as a peptide.

 Small amounts of the peptide are used.
 The amino acid chain is manipulated to
 achieve the desired characteristics,
 activity, potency.

 A larger scale of the synthesis is then
 created in order to initiate studies.

 Upon successful validation, a larger
 scale production synthesis is completed
Lab Synthesized Synthetic Ingredients

 These are substances that are
 formulated or manufactured by a
 chemical process or by a process that
 chemically changes a substance
 extracted from naturally occurring plant,
 animal, or mineral sources, except that
 this does not apply to substances
 created by naturally occurring biological
 processes

 These ingredients are specifically
 designed to perform a targeted function
Animal Derived Ingredients
 Animal derived ingredients are
 chosen by most cosmetic
 manufacturers to produce certain
 results

 Examples of this would be:
 albumen, whey, marine oils

 Our products are never tested on
 animals
Bases For Creams And Serums
 Base ingredients such as fatty
 alcohols, waxes, acids, fixatives,
 humectants,      coloring,   scents,
 binding, stabilizing and gelling
 agents help the formulator achieve
 certain characteristics in creams
 and to a lesser extent serums.

 Bases contribute to viscosity,
 moisturization, texture, feel, and
 help to bind certain ingredients to
 make a smooth emulsion.
Delivery Systems

 to a carrier such as a liposome

 If your high-tech ingredient does not reach the intended target
 in the body it will not respond as intended

 Our products rely on increasingly sophisticated delivery
 systems to put active materials exactly where they are needed
 most

 Enhanced skin delivery enables our formulators to achieve
 targeted and timed release of actives and enhance the
 efficacy and delivery of the effective concentration at the
 required site of action

 Enhancing penetration, makes the right delivery system
 critical in formulating hard-to-use ingredients


 peptides, hyaluronic acid, vitamin C and other vitamins,
 collagen and essential fatty acids as well as many other
 ingredients
Active vs Inactive Ingredients
 An active ingredient, is biologically active , it makes changes in the tissue or acts
 a catalyst for the body to act in a pre-determined way. It is responsible for
 producing a desired effect. It gives the product its main characteristics

 Materials that work physiologically within the skin or aid in protecting the skin
 from insult are also called active ingredients. Although a cosmetic, by legal
 definition, can only serve to beautify and protect the surface of the skin, many
 cosmetic products can be shown to penetrate the dermal layers of the skin to
 exact a physiological change. One must be careful to market only beautifying
 aspect of a product

 Peptides are an example of an active material They have the ability to penetrate
 the skin, where they can increase the production of collagen, elastin, and
 intracellular substances thus improving the appearance of the skin

 Thousands of cosmetic actives are used to affect the skin in a variety of ways.
 Some are used to lighten, tighten, and firm the skin

 Inactive ingredients are considered biologically inert and may serve as:
      the bases forming the products solution, waxes, emollients, coloring
      agents, fillers, diluents, preservatives, solvents, lubricants, etc.

 Most skin care products contain primarily in-active ingredients and add only a
 few select active ingredients at low concentrations. Our products contain 95%-
 99% active ingredients, these are the highest concentrations in the market.
Emulsions
  The majority of creams and lotions are emulsions



  liquid is dispersed as fine droplets in the other making it
  homogeneous
      Homogenized milk is an example of a typical oil-in-
      water (o/w) emulsion. Using an emulsifier called
      sodium caseinate

  The majority of emollients used in personal care and
  beauty items are fats and oils, also called lipids.

  Some of the key characteristics required in good
  emollients are good spreading properties, low toxicity/skin
  irritation and good oxidative stability.
Surfactants
Most emulsifiers can be considered surfactants or surface-active agents.
These materials are able to reduce the surface tension of water.
Example: Washing a greasy pan (fat) is easy with soap, because the
soap (surfactant), binds to the oil, and emulsifies with the water, it pulls
the grease off of the pan.

Fatty acids that are reacted with an emulsifier can form soaps. The
process of soap formation is called saponification. The negatively
charged stearic acid group is the main emulsifying unit of the soap, giving
it the anionic classification. Positively charged emulsifiers are called
cationic.

Nonionic emulsifiers are often used in skin-care emulsion for their safety
and low reactivity. Glycerin, commonly added to cosmetic emulsions for
its humectant properties, is the backbone of a class of emulsifiers called
Glyceryl esters .

Stearic acid is a major component of many of the fats and oils used in
beauty treatments, stearate-based emulsifiers are particularly useful.
Fatty acids are key components of many cosmetic emulsifiers due their
miscibility in a variety of natural and synthetic oils.

Esters polyethylene glycol or ethylene glycol are called PEG esters. A
PEG ester's solubility is determined by the number of PEG molecules
reacted per molecule of acid. In a formulation,        are typically used
for slip and feel.
Moisturizers
 The main distinction between moisturizers and emollients is their
 solubility in water. Healthy skin requires moisture. Moisturizers are
 generally polar materials that are hygroscopic in nature; they hold
 onto water

 Glycerin is a very cost-effective ingredient used to help reduce
 transdermal water loss

 Sorbitol, sucrose, glucose, and other sugars are also commonly
 used to hydrate the skin

 Aloe, which contains a mixture of polysaccharides, carbohydrates,
 and minerals, is also an excellent moisturizer

 Moisturizers lay on the surface of the skin and act as a protective
 barrier. But as a barrier they may block the penetration of other
 useful (ie. peptides) ingredients that need to reach deeper tissue
 levels to work
Waxes/Thickeners
Waxes

   Waxes are composed primarily of long-chain esters that are solid at room
   temperature. Common waxes used in cosmetics are beeswax, candelilla,
   carnauba, polyethylene, emulsifying, and paraffin.

   Waxes function as structuring agents, adding rigidity and barrier
   properties. By combining waxes with different properties you can add
   shine, flexibility, and brittleness

   Waxes are particularly useful in hand creams and mascara emulsions for
   their thickening and waterproofing properties.

Thickeners

   By incorporating enough wax into a thin lotion, a thick cream can be
   formed. Many thickeners are polymers. Cellulose, swells in hot water
   creating a gel network. Carbopol, a polyacrylic acid, swells when
   neutralized. Carrageenan, pectin, and locust bean gum are also all
   examples of cosmetic thickeners
Preservatives
Most cosmetic products require the addition of preservative to prevent
microbial contamination and rancidity

Parabens and ester of parabenzoic acid are by far the most commonly used
because of their effectiveness against gram-positive bacteria. We do not use
this group of preservatives.

Phenoxyethanol is used to protect against gram negative strains.

The cosmetic chemist will generally employ a mixture of preservatives to
protect against different bacterial strains as well as yeasts and molds

Antioxidants such as tocopherol (vitamin E) and BHT are also often added to
prevent oxidation of sensitive ingredients as well as protect the skin from free-
radical damage

Shelf life and product preservation is important to consider when the dynamics
of ordering , stocking and distribution are being determined

Efficacy, safety , environmental acceptance and international compliance are
all considered when we select a preservative
INCI Names
Ingredients are required to be listed on labels in INCI
compliant format

Ingredients are listed in quantity based descending
order; listing the ingredient with highest concentration in
the product first

INCI stands for the International Nomenclature Of
Cosmetic Ingredients



an ingredient acceptable in both US and international
markets

INCI names are a combination of scientific Latin names
and the English counterpart. An example of Raspberry
Extract would be Rubus Idaeus (Rasberry) Fruit Extract
Our Products
Our Products Contain 12 Peptides
12 Transforming Results

Dramatically Reduced Wrinkle Volume
Substantially Reduced Wrinkle Depth
Substantially Reduced Wrinkle Density
Improved Collagen Production
Improved Elastin Production
Improved Tightening
Improved Firmness
Dermal Substructure Reinforced
Improved Smoothness
Improved Tone
Tightened Pores
Wrinkle Producing Muscle Contractions Inhibited
Our Peptides
1.   Tripeptide-1 -restores collagen levels substantially. In vitro tests showed
     collagen 1 and collagen IV synthesis of 128% (collagen I) and 81% (collagen
     IV) respectively after 15 days. Collagen III tripled, this form of collagen is the
     most abundant type found in young skin. Tripeptide-1 is a technically
     advanced ingredient which renews the appearance of critical collagen fibers
     thus helping the body to rebuild the dermal structure. Study showed a 29%
     wrinkle depth reduction in 30 days.
2.   Palmitoyl Oligo Pentapeptide- It stimulates the production of collagen and
     fibronectin . Studies have shown collagen synthesis improved 117%,
     Collagen IV synthesis was improved by 327% and hylauronic acid synthesis
     increased by 267%. Wrinkle reduction 68%-90%.
3.   Dipeptide Diaminobutyroyl Benzylamide Diacetate (Synake) -Mimics a
     peptide found in the venom of the Temple Viper. It was designed as
     neuromuscular blocking compound acting at the post-synaptic membrane as
     a reversible block that prevents acetylcholine from binding to the receptor.
     One study demonstrated a 52% reduction in forehead wrinkles.
4.   Acetyl Hexapeptide-8 (Argireline) -Mimics the N-terminal end of Snap-25
     which competes for a position in the SNARE complex. When the SNARE
     complex is interrupted the vesicle         release the neurotransmitters that
     cause the muscle contractions which form a wrinkle. Studies showed wrinkle
     depth reduction of 17% in 15 days and 32% in 28 days.
5.   Pentapeptide-18 -Inhibits the release of acetylcholine across the neuro
     synapse. It keeps the neuron in a resting state which may interfere with the
     muscle contractions that form expression lines and wrinkles. In combination
     with Argireline studies show it reduces wrinkle depth of 25% to 47% within 28
     days.
Our Peptides
6. Acetyl Octapeptide-3 (SNAP-8) -Similar to Argireline but 30% more active.
    Decreases neuronal excitability by destabilizing the SNARE complex.
    Studies have shown wrinkle depth reduction by 63% in 30 days.
7. Palmitoyl Tripeptide-5 (SynCol) -
    collagen.
    Also provides skin firming and moisturizing. In vitro tests in human
    fibroblasts showed a 119% increase of collagen synthesis compared to the
    positive standard.
8. Pentapeptide-3 (Vialox) - It acts at the post-synaptic membrane blocking
    sodium ions. The result is that the muscles that form wrinkles stay relaxed.
    It inhibits muscle contractions by acting as an competitive antagonist at the
    AChR receptor.
9. Acetyl Tetrapeptide-5 Won the technology award in cosmetics in 2005.
    Enhances elasticity of the skin, and improves skin smoothness. It prevents
    collagen cross links from glycation elasticity loss and the formation of eye
    bags. It also helps to prevent liquid from accumulating and inhibits vascular
    permeability. In vivo tests of subjects ages 18-65 resulted in elasticity being
    improved by 30% in 30 days, puffiness was significantly reduced in 14 days
    and eye bags were reduced by 70% in 28 days. Dark circles under the eyes
    were also reduced.
10. Palmitoyl Dipeptide-5 Diaminohydroxybutyrate (syn-taks)- neuromuscular
    blocking compound acting at the post-synaptic membrane as a reversible
    block that prevents acetylcholine from binding to the receptor, resulting in no
    uptake of sodium ions. The effect is that it relaxes facial muscles, smoothes
    skin, and reduces the appearance of wrinkles. One study demonstrated a
    52% reduction in forehead wrinkles.
Our Peptides
11. Tripeptide-10 Citrulline Restores collagen levels substantially. In
    vitro tests showed collagen 1 and collagen IV synthesis of 128%
    (collagen I) and 81% (collagen IV) respectively after 15 days.
    Collagen III tripled, this form of collagen is the most abundant type
    found in young skin. Studies showed a 29% wrinkle depth reduction
    in 30 days. This peptide maintains a long-lasting collagen function
    that will help to ensure the appearance of healthy youthful skin.
12. Hexapeptide-10 A peptide that promotes cell adhesion, growth and
    migration, regenerating the basal lamina. A study showed cell
    growth increased by 74.6%. In addition to promoting cell adhesion
    and migration it also helps with the formation of blood vessels, and
    improves microcirculation. Cell proliferation results in compacted
    epidermis which provides firmness.
High Performance Skin Care
 4ce Of Nature provides a revolutionary approach to
 skincare using a collection of powerful serums to
 promote youthful skin

 The line includes 4 highly transformative, anti-wrinkle,
 peptide enriched medical grade serums that when
 layered form the treatment component of daily skin
 care regimen. Other serums in the line target a
 variety of skin problems



 experienced producing results far beyond
 expectations

 The studies in this slide series helps to demonstrate
 empirically the efficacy of our products
We Built Products With Real Substance
  95%-99% of our ingredients in each product
  are active ingredients

  Our most powerful ingredients are
  formulated in concentrations far above the
  levels found in competitive high-end
  products

  Our ingredients are class leading with award
  winning process technology

  All ingredients are sourced globally for their
  intensive performing characteristics
Transforming Innovative Ingredients Into
Marketable Products The Advantage Is Yours
 We broke away from conventional
 thinking to build our products with real
 substance and stunning results

 Our highly responsive products can be
 private labeled to position your
 organization for growth

 Our skincare system is powerful enough
 to build your business by bringing
 customers back to you monthly, with
 their friends in tow as referrals wanting
 to try these products
Why We Are Unique?
A Clinical Approach To Skincare
 We took a clinical approach to the design of our products. Our lead
 formulating chemist is also a biologist

 She along with our team of physicians approach the formulation process
 by analyzing the physiologic processes of the body that are
 compromised

 She looks at the cellular processes and selects ingredients that act to

 own repair mechanisms

 The skin care industry is notorious for selling low concentration, high
 profile ingredients that are minimally effective and highly profitable

 We took a different approach. We first consider the problem to be
 solved and the bodies physiology before ingredients are matched to
 solve the issue

 Our ingredients are selected for their targeted functions, as well as the
 magnitude of their force and ability to correct the issue we identified
Secret Formulation Techniques
We use closely held secret formulation techniques

They took several decades to develop

These techniques improve bioavailability, absorption, intensify
action, improve penetration, assist to transfer material to the
targeted cells, increase the results and shorten time of
response

These processes are what make us unique and give our
products a dramatic performance edge

Process engineering and unique ingredient sources makes our
products impossible to duplicate without our formula, giving you
one of a kind products
Bio-Vectored Formulas

We use bio-vectors to:
  Identify the depth of delivery

  Minimize the molecular size and use bonding to
  enhance penetration

  Achieve a high magnitude of impact and results

  Improve the immediacy of the solution

  Target the functional component in the transfer of
  supercharged ingredients to targeted areas
Our Highly Skilled Development Team

Responsive scientific team with expertise in:

        Analytical Chemistry

        Medicine (2 Physicians and a Nurse with Burn and
        Skin Care Expertise)

        Biology

        Microbiology

        Pharmacology

        Nutritional Supplementation

        Cosmeceuticals

        Process Engineering

        Aesthetics (Para-medical Aestheticians)
ANTI- WRINKLE PEPTIDE SERUM -1oz
The Most Targeted Peptide Enriched Product Available

  Re-awakens the cellular regeneration process

  Unique blend of eight powerful peptide ingredients

  Peptides are the most powerful ingredients in the
  anti-aging wrinkle reducing arsenal

  Reduces wrinkle volume, depth and density

  Encourages the body to rebuild collagen and
  elastin for visibly younger skin

  Process engineering and unique ingredient
  sources makes this product almost impossible to
  duplicate without our formula, giving you a one of
  a kind product
PEPTIDE SERUM INGREDIENTS
Tripeptide-1- patented active peptide that helps the body substantially restore
    collagen levels.
      Subjects studied from ages 35 to 55 showed a 29% wrinkle depth
         reduction in 30 days

Palmitoyl Oligo Pentapeptide - only a limited number of labs have access to this
   peptide due to patent restrictions. Stimulates the production of collagen and
   fibronectin promoting extracellular matrix renewal and cell proliferation.
   An in vivo (human based) study resulted in:
    the surface area of the deep wrinkles decreases by 68%, and in some cases
   was reduced by as much as 90%
   " the density of the main furrows: decreased by 47%
   " the area of the moderate wrinkles: decreased by 51%
   " the mean area of the main wrinkle: decreased by 22%

Stimulated the synthesis of the extra-cellular Matrix in vitro and ex vivo to very
    different extents:
    Collagen I : +117%
    Collagen IV : +327%
    It also stimulates the production of glycosaminoglycans: +267%.
Palmitoyl Oligo Pentapeptide Peptide #2

 Peptide #2, (one of twelve peptides used in our products) is a fragment
 of the C-terminal portion of collagen I



 synthesis of collagen I, collagen III and fibronectin

 It has a more marked impact on low-density cultures of fibroblasts than
 on higher density, confluent cultures

 This is relevant because it is closer to aging skin, which has a reduced
 population of fibroblasts
Deep Wrinkles Reduced By 68%-90%


 The surface area occupied by deep wrinkles was reduced by a
 mean of 68% over 6 months and in some cases was reduced
 by as much as 90%
 The density of the main furrows: decreased by 47%
 The area of the moderate wrinkles: decreased by 51%
 The mean area of the main wrinkle: decreased by 22%

 The concentration of this peptide in our products ranges
 between 8-16 times greater than the concentration used in this
 study
Significant Reduction In Wrinkles

                         Before Peptide #2 Use




                        6 Months After Peptide Use
Focus Ingredients
Dipeptide Diaminobutyroyl Benzylamide Diacetate (Synake) a neurotrasmitter blocker,
    relaxes facial muscles, smoothes skin, and reduces the appearance of wrinkles.
    One study demonstrated a 52% reduction in forehead wrinkles.

Acetyl Hexapeptide-8 (Argireline) - reduces the appearance of the depth of wrinkles caused
   by facial expressions.
   Studies showed wrinkle depth reduction of 17% in 15 days and 32% in 28 days.

Pentapeptide-18 - interferes with the formation of expression wrinkles.
   In combination with Argireline studies show it reduces wrinkle depth of 25% to 47% with in
   28 days.

Acetyl Octapeptide-3 (SNAP-8) - reduces wrinkle depth from the expression areas of the face
   .
    Studies have shown wrinkle depth reduction by 63% in 30 days.


Palmitoyl Tripeptide-5 (SynCol) -
   product collagen.

Pentapeptide-3 (Vialox) - peptide that offers intensive wrinkle care. It reduces expression line
   wrinkles and relaxes muscles.
Acetyl Hexapeptide-8 (Argireline) Peptide #4

 Peptide #4 was designed to reduce wrinkle depth caused by facial expressions
 (forehead and eyes)

 It is a neuro-transmitter blocking peptide

 It mimics the N-terminal end of Snap-25 which competes for a position in the
 SNARE complex



 neurotransmitters that cause the muscle contractions which form a wrinkle.

 Studies showed wrinkle depth reduction from use of this peptide, of 17% in 15
 days and 32% in 28 days.

 Silicone imprints were made for this study and measured by confocal
 profilometry
How It Works
 Muscles are contracted when they receive neurotransmitters released from a nerve cell in a
 process known as neuronal exocytosis

 The neurotransmitter involved is acetylcholine and it is released from a vesicle into the
 synapse

 The process involves several proteins, channels and vesicles

 The SNARE protein complex is essential for neurotransmitter release at the synapsis and
 mediates the final steps of exocytosis

 It is a complex formed by three proteins: VAMP, Syntaxin and SNAP-25

 This complex is like a cellular hook that captures vesicles (a process called docking) and
 brings them close to the membrane to enable their fusion
How It Works
               Neuro-transmitter acetylcholine
               and it is released from a vesicle
               into the synapse

               The SNARE protein complex is
               formed by 3 proteins, VAMP,
               Syntaxin, and SNAP-25 and it is
               essential for neuro-transmitter
               release at the synapse and
               mediates the final steps of
               exocytosis

               Acting as cellular hook it
               captures vesicles and brings
               them close to the membrane to
               enable fusion
SNAP
Bio-Chemical
Mechanism
Botlinum Toxin A
Botulinum Toxin A paralyses the muscle by
selectively blocking acetylcholine release
at the neuromuscular junction

BoNT-A cleaves the protein SNAP-25
irreversibly, and therefore the SNARE
complex cannot assemble

The nerve signal cannot be relayed, the
muscle cannot contract and it is paralyzed.
Destabilized SNARE Complex,
Peptide #4
    If the SNARE complex is slightly
    destabilized, the vesicle cannot release
    neurotransmitters. As a consequence,
    muscle contraction is attenuated and the
    muscle is relaxed




                              Peptide #4 is a mimic of the N-terminal
                              end of SNAP-25 and it competes with
                              the natural protein for a position in the
                              SNARE complex, so it destabilizes its
                              formation, without breaking any of its
                              components
In Vitro Efficacy

Inhibition of glutamate release
at mM concentrations is a
clear indicator of the potent
anti-expression wrinkle activity
of the peptide.

Inhibition of glutamate release
by depolarized neuron is a
validated cell assay for
measuring       the    potential
activity of compounds on the
inhibition      of     neuronal
exocytosis.

Untreated neuron cultures
were used as a negative
control and cultures treated
with Botulinum Toxin A (BoNT-
A) were used as a positive
control
Two In-Vitro Tests Related To The
Formation Of Wrinkles


                   Reduction in the depth of
                   wrinkles up to 17% after 15 days
                   with 10% Peptide # 4 solution




                   The depth of the furrow
                   decreased a maximum
                   value of 32% in 28 days
                   with a cream containing
                   5% Peptide #4 solution.

                   The concentration in our
                   formula is much higher
Another Study
 This peptide reduces the severity
 of wrinkles around the eyes, up to
 17% after 15 days of treatment
 and up to 27% after 30 days of
 treatment

 Objective:
 To determine the effectiveness of
 the peptide #4 cream in reducing
 the severity of wrinkles
Reduced
wrinkle depth
up to 27% in
30 days
Volunteer nº5
(38 years)


 Base




 Peptide 4
Volunteer nº3 (54 years)
Volunteer nº3 (54years)
 Video Sequence
Volunteer nº7 (45 years)
  Video Sequence
Dipeptide Diaminobutyroyl Benzylamide
Diacetate (Synake)
A neuro-transmitter blocking Peptide

  A small peptide that mimics the activity of a
  polypeptide found in the venom of a Viper
  Capable of reducing mimic wrinkles by
  inhibiting contractions
  Reduced forehead wrinkles by 52%
Ra: average roughness
Rt: maximum difference between the highest peak
and the deepest furrows
Rz: mean value of these different maxima              Study On Smoothing
A decrease of the Ra expresses a smoothed relief
A decrease of the Rt and Rz expresses a decrease of
                                                        And Anti-Wrinkle
wrinkle depth                                         Effect Of Peptide # 3
Wrinkles Decrease 52% On The Forehead




Measurements on Volunteer #29 showed that Peptide #3 was able to
reduce forehead wrinkles by up to 52%

In vitro measurements showed that Peptide #3 (at a concentration of
0.5mM) was able to reduce the frequency of contractions of
innervated muscle cells by 82% (p<0.05) after 2 hours of treatment


and anti-wrinkle effect on this area
Wrinkle Height Profile




Using the PRIMOS® technique, parallel stripe patterns are
projected on the sample with successive phase shift.

The analysis of fringe deformations provided a qualitative
and quantitative evaluation of each height profile
Acetyl Octapeptide-3 (SNAP-8) Peptide #6

 A wrinkle reducing peptide that is similar to
 Argireline but 30% more active.

 It reduces wrinkle depth from the expression
 areas of the face such as the forehead and
 eyes.

 It decreases neuronal excitability by
 destabilizing the SNARE complex.

 Studies have shown wrinkle depth reduction
 by 63% in 30 days.
Inhibition Of Snare Complex Formation




Demonstrates the blocking of SNARE complex formation. The lower the
SNARE complex in vitro, the higher the efficacy of the anti-wrinkle cream.

Evaluated the antagonistic competitive efficacy of the peptide patterned after
SNAP-25 N-Terminal domain compared to native SNAP-25(positive control).
Peptide #6 has the capacity to assemble with syntaxin and synaptobrevin
forming the SNARE complex, which was measured.

Heat and consequent thermal decomposition was the negative control
Modulation Of Glutamate Release In A Neuron Cell Culture




                        Peptide #6    Peptide #6




Glutamate is the most excitatory abundant neurotransmiter in the nervous system.


The release of glutamate in a primary cell culture of neurons was measured to
compare the in vitro activitiy of Peptide 6 and Botulinum Toxin A (positive control)

Peptide #6 inhibits glutamate release in a dose-dependent manner
63% Reduction Value Of Wrinkle Depth With Peptide #6




Skin topography analyses were performed to measure the effectiveness of
a cream containing 10% Peptide #6

Silicon imprints were obtained from around the eyes of 17 women
volunteers pre-test and after the 28 day treatment.

Analyses of imprints were performed by confocal profilometry
Bonnie After Using The Peptide Serum

                         Day 0




            Week 3
Stem Cell Serum
Using state of art technology to culture plant stem cells

Based on high-tech bioreactor plant cell culture technology, that was awarded the
   Innovation Award in 2008

First stem cell ingredient is from a rare apple, known for its longevity
    A study with our first ingredient with subjects between the ages of 37-64,
    showed a significant and visible decrease in wrinkle depth for 100% of the
    subjects by the 28 days.
    Study results showed that the CFE (colony-forming efficiency) was stimulated
    by 92% in the presence of 0.04% of the stem cell extract. This clearly showed
    an improved maintenance of the stem cell characteristics of epidermal stem
    cells.

Second plant stem cell ingredient is from a rare Gamay grape ,which has extremely
   high anthocyanins, this ingredient fights photo-aging and delays cell death
   Study results showed this stem cell extract to strongly increase CFE: the CFE
   was stimulated by almost 80% Clearly showing that it helps the epidermal stem
   cells maintain their stem cell characteristics.
Why Use Plant Stem Cells


 Epidermal stem cells rejuvenate and promote the balance of
 cells in the skin and help to regenerate damaged tissue.

 Aging reduces the number of stem cells in the skin and
 diminishes their ability to repair the skin.

 Plant stem cells contain specific epigenetic factors that help to
 maintain the regeneration capacity of stem cells in the skin.

 The result is a remarkable improvement in the appearance of
 the skin as well as a reduction in wrinkles, and protection
 against oxidative stress.
Focus Ingredients
Malus Domestica Fruit Cell Culture - Awarded the Innovation
  Award in 2008. It uses a liposomal delivery system and is
  based on plant stem cells from an endangered fruit(apple) that
  is known for its longevity. Studies have demonstrated its
  remarkable age delaying and anti-wrinkle effects in humans.

Palmitoyl Oligo Pentapeptide - Promotes collagen helps to
  improve the visible signs of aging.

Vitis Vinifera (Grape) Fruit Cell Extract - Plant stem cells contain
   specific components, called epigenetic factors. They regulate
   the activity and the function of the cell. These plant stem cells
   improve the vitality of skin stem cells, and protect them against
   negative environmental influences
Improvement Using Apple Stem Cell

                    Before (day 0) of use of our
                    Apple Stem Cell




                    After (day 28)
TIGHTENING SERUM- 1 oz
Reduce The Appearance Of Loose Skin And Enlarged Pores


  Contains peptides designed to help you look younger
  by increasing the elastin and collagen in your skin

  Reduces the appearance of loose skin and improves
  the skins resilience

  Improves cell proliferation resulting in a more
  compacted epidermis which provides firmness

  Provides a noticeable tightening effect, strengthens
  connective tissue, and provides protection against
  oxidative stress.
Focus Ingredients
Tripeptide-10 Citrulline - A peptide that substantially restores collagen levels.
    Showed a 29% wrinkle depth reduction in 30 days. This peptide maintains a long-lasting
    collagen function.

Pullulan - An anti-oxidant that also helps to retain moisture.

Hexapeptide-10 - A peptide that promotes cell adhesion, growth and migration, regenerating
   the basal lamina. Tests have been carried out to quantify the increase in cellular adhesion
   of keratinocytes and fibroblasts.
   A study showed cell growth increased by 74.6%.

Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine (syn-taks) - It helps to restore
   the structural integrity of the skin, reducing wrinkles, and improving tone.

Palmitoyl Dipeptide-5 Diaminohydroxybutyrate (syn-taks) - It helps to restore the structural
   integrity of the skin, reducing wrinkles, and improving tone.

Enteromorpha Compressa Extract - An edible form of green algae that produces a large
    array of bioactive compounds found useful in the treatment of inflammation, allergies and
    bacterial and viral infections.

Theobroma Cacao(Cocoa) Extract Provides anti-oxidant and anti-stress effects for skin
   preparations. Acts as a skin balancer and energizer reducing cell degeneration and
   protecting the skin from cell damage.
PEPTIDE EYE SERUM-! oz
Award Winning Ingredients Used In This Powerful Peptide Serum




  Exciting powerful eye serum
  using award winning ingredients.

  This product provides dramatic
  reductions in baggy eyes, dark
  circles, fine lines and wrinkles.

  Returning the skin to a much
  more youthful state.
Focus Ingredients
Acetyl Tetrapeptide-5 - Won the technology award in cosmetics in
  2005.
        In vivo tests of subjects ages 18-65 resulted in elasticity being
       improved by 30% in 30 days,
        puffiness was significantly reduced in 14 days and
       eye bags were reduced by 70% in 28 days.
        Dark circles under the eyes were also reduced.


Acetyl Octapeptide-3 (SNAP-8) It reduces wrinkle depth from the
  expression areas of the face such as the forehead and eyes. It
  decreases neuronal excitability by destabilizing the SNARE
  complex.
   Studies have shown wrinkle depth reduction by 63% in 30 days


Dipeptide Diaminobutyroyl Benzylamide Diacetate (Synake) - A
   wrinkle reducing active peptide that mimics a peptide found in the
   venom of the Temple Viper. It was designed as neuromuscular
   blocking compound acting at the post-synaptic membrane
   One study demonstrated a 52% reduction in forehead wrinkles.
EYE LASH LENGTHENER                                        10ml
We Broke From Conventional Thinking When This Product Was Designed



                       Unparalleled combination of class
                       leading formulation processes and
                       performance based ingredients

                       Uses Keratinocyte Growth Factor
                       partnered with a variety of powerful
                       ingredients that benefit the follicles
                       ability to add new hair.

                       We set the stage by improving the
                       environment for growth and then
                       added the trigger that makes it
                       happen.
Focus Ingredients
L-Acetyl Carnitine - Reactivates the hair follicles. Transfers fatty acids to the
   mitochondria to be used as energy and to enhance active metabolism needed
   for cellular repair.

Niacinamide - An anti-inflammatory and vasodilator. It stimulates collagen and acts
   as an anti-oxidant. It reduces inflammation.

Soy Isoflavones - Helps preserve elasticity limiting the breakage of hair.

Saw Palmetto Extract - Thought to block cell receptor sites required to absorb
   DHT. May improve hair growth, maintains healthy hair and helps to reverse
   hair loss.

Keratin - Primary constituent of hair it wraps the hair follicle with a keratin bond that
   protects and strengthens the hair shaft.

Nettle Extract - Partially blocks 2 enzymes, 5a-reductase, which makes
   dihydrotestosterone (DHT) and aromatase enzyme. These enzymes are
   thought to block hair growth.

Hexanoyl Dipeptide-3 Norleucine Acetate: - A peptide that activates follicle
   regeneration.
Focus Ingredients
Lecithin- A natural emulsifier and lubricant. It also protects cell follicles from
    oxidation and breakdown.


L-Arginine - An amino acid that may bring oxygen to the tissue. It may act on
    the follicle by promoting the formation of L-proline, an amino acid that is
    essential to the synthesis of collagen. It is thought to play a role in cell
    division.


L-Glutamine - An amino acid that helps with cell rejuvenation. Acts as an eye
    tissue nutrient.


Zinc - Benefits cellular growth and appears to limit DHT production. It helps
    with absorption of vitamins and proteins that are necessary for hair growth
    and maintenance.


Keratinocyte Growth Factor (KGF) - A growth factor that promotes hair
    growth, it is synthesized by fibroblasts. A complex growth factor it contains
    an 160 amino acid chain that stimulates cell replication. This is made
    specifically for our product.


Superoxide Dismutase - An enzyme that prevents oxidative stress and
    enhances antioxidant balance. SOD is found in the dermis and epidermis
    and is important in the production building new cells.
LIGHTENING SERUM                                  1 oz
Revolutionary Serum Significantly Lightens And Reduces The Appearance Of Skin
Discoloration




   An aesthetic treatment that significantly
   reduces the appearance of skin discoloration
   and lighten and brightens the appearance of
   the skin.

   Each individual responds differently to
   ingredients, we approached this issue by using
   ten distinctly different skin lightening
   ingredients.

   Each ingredient operates in a slightly different
   way to ensure that the outcome will be what
   you expect.
Focus Ingredients
Diaminopropionoyl Tripeptide-33 - A peptide that reduces the appearance of
   photo-aging. It promotes the DNA repair systems capacity, and provides the
   skin protection from aging.

Arbutin - Arbutin has a depigmenting effect on the skin. Increases cutaneous
   luminosity, cutaneous smoothness, with a significant reduction of cutaneous
   tint, and cutaneous dyschromia.
     Inhibits the tyrosinase enzyme and has been documented by in vitro
         studies to have an enzymatic inhibition level of 56%.

Kojic Acid - An effective skin lightener, inhibits melanin production, helps to
   balance skin tones, fading dark spots and freckles caused by sun exposure,
   aging, and cutaneaous hyper-pigmentation.

Licorice Root - A skin whitener, anti-inflammatory, anti-microbial and anti-oxidant.

Magnesium Ascorbyl Phosphate - It significantly affects the appearance of skin
  lightening acting to inhibit tyrosinase to reduce the formation of melanin. It also
  promotes collagen synthesis.
Focus Ingredients
Bellis Perennis (Daisy) Flower Extract - Highly efficient natural skin lightener by
    influencing melanin formation.
          An in vitro study done in the Philippines showed a reduction of tyrosinase and
          tyrosinase activity resulting in a significant lightening effect.


Diacetyl-Boldine - A skin lightener, was shown to be 30 times more effective than kojic
    acid.
    In vitro tests showed it inhibited the activity of tyrosinase by 56%.
    A study of Asian subjects showed skin lightening improved by 71%, hyper-pigmented areas
    decreased by 54%, complexion was viewed as 65% move even, and 74% more radiant.
    A study of Caucasian subjects showed a 23% reduction in age spots. It provides the skin
    with an even, luminous and mat complexion.


1-aminoethylphosphinic acid - Used as a skin lightener to reduce age spots. Acts
    different from tyrosinase inhibitors, it slows down melanogenesis providing a whitening
    effect by decreasing melanin systhesis at the DOPA-Chrome level


Dimethylmethoxy Chromanyl Palmitate - Provides considerable skin lightening.
    A study of Asian women ages 18-46 showed a 37% inhibition of tyrosinase activity, it
    stopped endogenous tyrosinase activity by 43% and was found to have a better di-
    pigmenting effect than Kojic acid.
CELLULITE CREAM                                 5 oz
Finally A Solution That Actually Works



 This intensely effective approach to lustrous,
 youthful, smooth skin, reduces the appearance
 of cellulite.

 A Brazilian study of 99 women showed more
 than
      88% experienced a decreased circumference their thighs and arms
      68% saw an additional reduction of their hip size when the caffeine
      ingredient was analyzed.



 Pseudoalteromonas Ferment Extract study
 showed
      128% increase in collagen 1 within 15 days
      81% increase in type IV collagen
Focus Ingredients
Lecithin - May reduce the accumulation of fluids, reduce inflammation and improve
    circulation. Helps the body improve the support structures under skin to keep cellulite from
    showing through.


Caffeine - Vasoconstrictor, reduces fluid retention and may improve fat metabolism.

Butcherbroom (Ruscus Aculatus) Root Extract - Decreases excess fluids, anti-
    inflammatory.


Tea-Hydroiodide - Is a skin conditioning agent.

Ivy (Hedera Helix) Extract - Tones, tightens and helps reduce build up of waste products
    in tissue.


Carnitine - A naturally occurring amino acid supports the transport long chair fatty acids to
    the mitochondria where it is used for energy. Thought to improve appearance of dimpled
    skin.


Tripeptide-1 - A patented peptide that acts as a skin conditioning agent.

Panthenol - Provitamin B5 has the effect of filling in areas and stretching the skin.
Focus Ingredients
Marrubium Vulgare Extract - An anti-inflammatory that assists in absorption.

Pseudoalteromonas Ferment Extract - A glycoprotein found at the bottom of a glacier in Antartica, it is
     thought to increase elastin and collagen.

     One study showed a 128% increase in collagen 1 within 15 days and a 81% increase in type IV collagen.

Acetyl Tetrapeptide-5 - A peptide that reduces edema in tissue.

Pentapeptide-18 - A neuropeptide that helps to relax muscles and tighten the skin.

Rucus Aculeatus Root Extract - Improves microcirculation in the skin, and capillary permeability.

Citrus Medica Limonum Peel Extract - Benefits circulation and helps improve blood flow.

Solidago Virgaurea Extract - Improves circulation, contracts tissue, reduces fluids.

Astragalus Membranaceus Root Extract - Benefits micro-circulation, firms and smoothes the skin and
     helps to reduce the appearance of imperfections.

Ilex Paraguariensis Leaf Extract(Yerba Mate) - Has a relaxing effect on muscle tissue, burns fat.

Cameilia Oleifera Extract(Green Tea) - Rich in anti-oxidants and anti-inflammatory properties.

Cola Acuminata Seed Extract - Provides the stimulating and fluid draining effects of caffeine. Improves
     texture on uneven dimpled skin.

Japanese Pepper Extract: - A pepper that results in a hot or tingling sensation to the skin. It is an anti-
     oxidant that also benefits microcirculation. Anti-inflammatory.
FACIAL/BODY HAIR INHIBITOR                                          1 oz
Dramatically Reduce The Appearance Of Unsightly Hair


 Hair growth cycles can take 3-4 months with 80% of
 your hair in a growth cycle at any one time.

 Most cultures dictate the aesthetic level of hair for
 both men and women and social acceptance is
 affected for those who violate those norms.

 It effectively helps to dramatically reduce the
 appearance of unsightly hair
      A study on one of our key ingredients showed a decrease
      of 30% in hair length and a 16% reduction in density within
      60 days.
Focus Ingredients
Larrea Diviaricata Extract - A hair growth inhibitor that also has anti-oxidant and
   anti-microbal properties.

Lauryl Isoquinolinium Bromide - A major hair growth inhibiting ingredient. It
   decreases the length and density of hair, reduces the need for shaving or
   depilation. It targets the hair follicle cells and decreases new hair formation.
   One study showed a decrease of 30% in hair length and a 16% reduction in
   density within 60 days.

Pseudoalteromanoas Ferment Extract - It maintains natural bio-protective
   properties and promotes keratinocyte growth and fibroblast adhesion for a skin
   regenerating effect.
    A study showed increased collagen I synthesis by 81% after 7 days and 128%
   after 15 days and increased collagen IV synthesis 36% after 7 days and 81%
   after 15 days.

Subtilisin - A keratinolytic protease that invades the hair structure and causes
   proteolytic cleavage which reduces intercellular adhesion and reduces hair
   growth. It also diminishes the size of hair follicles and hair shafts.

Palmatine - Slows mitosis and therefore reduces hair growth.
New Products
 Roll Off Wrinkles A strong peptide formula that comes in bottle with a roller ball. It can
 be carried in your pocket or purse and used throughout the day. It is particularly designed
 to eliminate the more difficult wrinkles

 Anti-Oxidant Serum A serum loaded with anti-oxidants that will protect the skin from free
 radical scavengers, nourish and revitalize it

 Telomer Protect Serum - The discovery of telomeres won the 2009 Nobel Prize in

 youthful cell function. Every time your cells divide, your telomeres shorten. When your
 telomeres become too short, cell division stops and your cells can no long divide to build
 new cells. This product helps maintain telomeres and extend the lifespan of your skin cells.

 up your sagging skin

 Inside Out Beauty Supplement Designed using three proprietary blends of the
 ingredients. The first is a powerful blend of amino acids which encourages the body to
 produce Human Growth Hormone. This hormone declines with aging and that loss results
 in a loss of energy, stamina, strength, muscle tone and skin tone, thickness and wrinkle
 formation. This blend can dramatically assist the body to achieve the vigor and
 characteristics of a more youthful state. The other two blends focus on adding anti-
 oxidants to the body to improve both health and beauty.
Nutritional
Supplements
Why We Are Unique
 We use the highest quality ingredients

 We formulate using high concentrations of the most potent ingredients

 We use semi-manual encapsulation processes to eliminate the need for excipents

 We perform vendor audits, and all ingredients are tested for purity, potency, authentication

 We participate in an extensive audit by an outside auditing company

 We use the most cutting edge advancements to aging in recent history

 An unparalleled approach to beauty and wellness

 95%-99% of our ingredients in each product are active ingredients

 Our formulation team includes physicians

 Our formulations use clinical strengths of medical grade ingredients

 All products are manufactured in house in our fully accredited manufacturing plant
Appetite Suppressant/Thermogenic
 This appetite suppressant works by
     Diminishing appetite

     Increases the sensation of fullness
     Improves mood
     Helps to develop a perceived sense of happiness

 Unlike other supplements this product approaches appetite suppression from
 many angles, and gives the body several opportunities to feel satiety.

 It acts as a thermogenic
 burning of fat.

 It is caffeine, and ephedra free.

 It controls appetite during times of boredom or emotional distress.
WEIGHT LOSS CARBOHYDRATE CONTROL - 180 caps
The Help You Need To Control Carbs



Helps to break the vicious weight gain cycle
 and control carbohydrate cravings.
       Helps reduce the absorption of starch
        Breaks down carbs into absorbable sugars
       Helps the body better regulate glucose and insulin
       Improves pancreatic function by mediating insulin
       release
       Helps the body better use calories and metabolize
       glucose
       Reduces carbohydrate cravings
       Stimulates the brain to feel satisfied and full
WEIGHT LOSS FAT BURNER (LIPOTROPIC) - 60 caps
Power Up Your Ability To Burn Away Fat


  This supplement helps to:
     Control appetite and improve mood
     Breakdowns fat and converts it to energy
     Removes and metabolizes excess fat from the
     liver

       its effect on fat storage



       formation on arterial walls
NATURAL HAPPINESS                                60 caps
Renew Your Sense Of Joy, Re-energize Your Life



   A non sedating formula that helps
   maintain and elevate mood levels

   Combats fatigue

   Increases energy levels and
   improves malaise

   Helps minimize depression and
   relieve tension, irritability, stress
   and anxiety

   Improves memory
LIVER SUPPORT                            180 caps
Is Your Liver Working Overtime? What Are You Doing To Protect It?



  Aids in liver detoxification

  Improves digestion

  Enhances bile production and flow

  Assists in neutralizing and
  eliminating toxins, provides anti-
  oxidant benefits

  Helps protect the liver from damage
  and supports its optimal functioning
MENOPAUSE SYMPTOM RELIEF                   60 caps
Live Comfortably As Menopause Approaches



  Improves menopause symptoms

  Helps regulate mood swings

  Helps regulate hormonal swings
  Reduces hot flashes and night sweats

  Minimizes weight gain

  Improves bladder incontinence and
  overactive bladder
JOINT SUPPORT                            480 grams
Reduce Pain, Swelling, Tenderness And Stiffness


   Helps build synovial fluid and cartilage

   Improves mobility and reduces discomfort

   Improves health and function of cartilage

   Reduces pain, swelling, tenderness and
   stiffness

   Improves athletic recovery
MUSCLE CRAMP OIL                             4oz
Stop Painful Sudden Forceful Muscle Cramps



  Helps restore magnesium levels in the body
  Helpful to athletic recovery
  Helps relieve aches, pain, muscle cramps,
  and stiffness
  Helps maintain muscle function
  Calms nerves
  Supports restful sleep
  Highly absorbable without GI side effects
  common with oral version and acts quickly
Q IMMUNE                       120 caps
An Unprecedented Approach To Immune Support


The discovery of the biologic importance of our key ingredient
Germanium has been touted as a landmark development in the field of
nutritional and metabolic medicine

Dramatically improves the efficiency of oxygen utilization at a cellular
level

Each atom of germanium is bonded to three atoms of oxygen, making it
an efficient carrier of oxygen, it is believed oxygen cannot be properly
metabolized by cancer cells

Powerful regulator of the immune system, activating an under-active
system and suppressing over-activity when necessary

Our unique proprietary engineered blending process transforms this
combination of ingredients and dramatically enhances their
     effectiveness
     bioavailability
     provides a compounding effect with the supporting
     ingredients
4ce Of Nature
and one of a kind.



   technology, and process engineering as we
   transform our secret processes and a set of
   incredibly responsive ingredients, into highly
   responsive products.



   ever experienced
   Producing rapid and stunning changes to the
   skin
   Transforming tired, aged, wrinkled skin into
   vibrant youthful restored skin
   Protecting younger skin from the ravages of
   aging
4ce Of Nature

Using highly concentrated peptide enriched formulas our products
  produce astounding results.

  Nothing currently on the market comes close to our products
  performance

  Process engineering offers our products a unique edge and protects
  against competitors attempts at duplication

  Small molecular sizes allow deep penetration

  Unique delivery systems maximize absorption

  Careful PH balancing help our products to penetrate deeper and
  respond faster
Private Label Peptide Skin Care from 4ce of Nature

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Private Label Peptide Skin Care from 4ce of Nature

  • 2. Who Are We? A fully credentialed manufacturer of high performance skin care products and health benefiting supplements We offer a stock line of low minimum products (6 units per product) Our products are labeled and branded using our clients name We use medical grade, high potency ingredients formulated at very high concentrations
  • 3. What We Do? We provide innovative high end skin care products and nutritional supplements to: Skin Care Physicians-Plastic Surgeons, Dermatologists Naturopaths High-End Spas Destination and Resort Spas Medi-Spas Supplements Physicians Naturopaths Chiropractors Sports Stores Gyms Supplement Stores
  • 4. What We Do? Provide a science based approach to formulation using experienced chemists and physicians We search world wide to source the most powerful and effective ingredients. France, Switzerland, Germany, Italy, Australia and many more We use breakthrough innovative ingredients that are considered best in their class We provide the most powerful ingredients available, and they are formulated in higher than expected concentrations We offer a convergence of science, advanced engineering, and highly responsive ingredients
  • 5. 95-99% Of Our Ingredients Are Actives
  • 6. What We Do? Our products benefit all age groups and skin types but our focus is: oxidative stress and visual elastin beauty wrinkle Anti-Aging reduction
  • 7. What We Do? The Skin Care Company? We stimulate the skin for rapid and dramatic improvements in its appearance Dramatically improve the appearance of: fine lines and wrinkles reduce the appearance of age spots discolorations improve skin elasticity and collagen production improve texture reduce puffiness improve skin hydration and tone
  • 8. What We Do? Our anti-aging products are designed to produce extraordinary results Designed to be at the head of the most impressive class of skin care products Nothing currently on the market comes close to matching their effectiveness that are formulated at very high concentrations specifically designed to work synergistically designed to be highly bio-available and penetrate deeply
  • 9. What We Do? Scientific team of chemists, physicians, para- medical aestheticians and other healthcare professionals State of the art ingredient technology High levels of bio-actives Molecular engineering Process engineering
  • 10. Credentialed Manufacturing State of the Art manufacturing facility with an: In-house analytical & formulation laboratory Separate enclosed production clean rooms Ambient clean air system Water purification and monitoring systems Vendor certification program Ingredient authentication Global sourcing cGMP Certified NSF Certified FDA Audited
  • 11. Owned By Healthcare Professionals Dr. Angela DeRosa DO, MPH, CPE,(Chief Medical and Compliance Officer), board certified Internist specialized in two AZ medical schools, past senior medical director for P&G Pharmaceuticals. Mirijana Potocnjak, (Chief Scientist and Operations Officer) is a biologist/chemist with 13 years of nutraceutical and skin care product development experience. Extensive background in herbs, botanicals, and organic ingredients. She is the primary formulating chemist for our products. Judy Curran RN, (Chief Executive and Marketing Officer) educated both as a Registered Nurse and in Business, has over 30 years experience in domestic and international business and product development within the health and beauty industry. Clinical experience in Burns, Wound Care, and Skin Care.
  • 12. Stock Product Line SKIN CARE PRODUCTS SUPPLEMENT PRODUCTS PEPTIDE ANTI-AGING SERUM -1oz THERMOGENIC APPETITE STEM CELL SERUM ! oz SUPPRESSANT TIGHTENING SERUM 1 oz WEIGHT LOSS CARBOHYDRATE CONTROL PEPTIDE EYE SERUM - ! oz WEIGHT LOSS FAT BURNER EYE LASH LENGTHENER (LIPOTROPIC) LIGHTENING SERUM 1 oz NATURAL HAPPINESS CELLULITE CREAM 5 oz LIVER SUPPORT FACIAL/BODY HAIR INHIBITOR 1 oz MENOPAUSE SYMPTOM RELIEF JOINT SUPPORT MUSCLE CRAMP OIL Q IMMUNE
  • 13. Biology, Peptides And Serums Understanding The Basics Of Our Formulas
  • 14. Why We Use Serums As Our Product Base? Cosmetic serums are highly concentrated skin treatment products Ingredients in serums are generally 10 times more concentrated and biologically active than in creams Serums use powerful targeted ingredients of small molecular sizes in order to penetrate deeper and more quickly than creams Serums are considered the primary vehicle to deliver supercharged ingredients
  • 15. Example Of Peptide Serum Results Week 3 Day 0 Week 1
  • 16. Understanding Serums Serums do not clog pores Serums are generally selected to achieve a very focused result such as wrinkle reductions They generally offer a single or limited action verses other products which use more ingredients at lower concentrations to try to tackle a large number of actions Serums are designed to penetrate and not act as a moisturizing barrier therefore, clients with dry skin should apply a moisturizing layer after the serums have absorbed
  • 17. Improvement Using Plant Stem Cells 4',%$'*-./0*53*67'*%,*%6$*8)'"*9'::*;<* !"#$%&'"'()*+,)'$*-./0*123*
  • 18. Serums Serums often seem miraculous because they show some of their beneficial results almost immediately and the visible changes can be very dramatic Serums can be used by any age client from teen to adult Serums can be matched to various skin types and conditions through ingredient selection
  • 19. Serums vs Moisturizers Moisturizers use ingredients with larger molecular lipids topically and create a moisture barrier Moisturizers leave a fine film on the surface of the skin whereas serums deliver their ingredients deeper into the tissue Serums use more active ingredients which are targeted to change the characteristics of the skin Once our serums have been absorbed a moisturizer can be applied if needed
  • 20. Ingredient Categories Natural Earth Harvested Ingredients Natural Lab Constructed Ingredients Lab Synthesized Synthetic Ingredients Animal Derived Ingredients Bases For Creams And Serums Delivery Systems Active vs Inactive Ingredients Preservatives
  • 21. Natural Earth Harvested Ingredients Natural earth harvested ingredients include: Standardized botanicals, organics and wild crafted botanicals Extracts, Essential Oils, Purees Herbs Minerals Ingredients in their naturally harvested state are often not well absorbed topically due to large molecular sizes and may not be concentrated or specific enough to produce noticeable positive results on the skin It is difficult to formulate sophisticated 100% organic products that can achieve our performance goals, but the use of some organic ingredients can be a marketing advantage
  • 22. Natural Lab Constructed Ingredients Natural lab constructed ingredients are copied in the lab, on a molecular level, to mirror nature Organic chemists build identical molecular replicas of earth-natural ingredients except that they screened and designed to focus on a particular function which will yield the targeted results we are seeking This includes many peptides, other amino acids, vitamins, some anti-oxidants etc. Most of our ingredients fit this category
  • 23. Peptide Synthesis Methodology Generally a biomedical researcher will explore the possibility of increasing the native potency or performance characteristics of a given substance, such as a peptide. Small amounts of the peptide are used. The amino acid chain is manipulated to achieve the desired characteristics, activity, potency. A larger scale of the synthesis is then created in order to initiate studies. Upon successful validation, a larger scale production synthesis is completed
  • 24. Lab Synthesized Synthetic Ingredients These are substances that are formulated or manufactured by a chemical process or by a process that chemically changes a substance extracted from naturally occurring plant, animal, or mineral sources, except that this does not apply to substances created by naturally occurring biological processes These ingredients are specifically designed to perform a targeted function
  • 25. Animal Derived Ingredients Animal derived ingredients are chosen by most cosmetic manufacturers to produce certain results Examples of this would be: albumen, whey, marine oils Our products are never tested on animals
  • 26. Bases For Creams And Serums Base ingredients such as fatty alcohols, waxes, acids, fixatives, humectants, coloring, scents, binding, stabilizing and gelling agents help the formulator achieve certain characteristics in creams and to a lesser extent serums. Bases contribute to viscosity, moisturization, texture, feel, and help to bind certain ingredients to make a smooth emulsion.
  • 27. Delivery Systems to a carrier such as a liposome If your high-tech ingredient does not reach the intended target in the body it will not respond as intended Our products rely on increasingly sophisticated delivery systems to put active materials exactly where they are needed most Enhanced skin delivery enables our formulators to achieve targeted and timed release of actives and enhance the efficacy and delivery of the effective concentration at the required site of action Enhancing penetration, makes the right delivery system critical in formulating hard-to-use ingredients peptides, hyaluronic acid, vitamin C and other vitamins, collagen and essential fatty acids as well as many other ingredients
  • 28. Active vs Inactive Ingredients An active ingredient, is biologically active , it makes changes in the tissue or acts a catalyst for the body to act in a pre-determined way. It is responsible for producing a desired effect. It gives the product its main characteristics Materials that work physiologically within the skin or aid in protecting the skin from insult are also called active ingredients. Although a cosmetic, by legal definition, can only serve to beautify and protect the surface of the skin, many cosmetic products can be shown to penetrate the dermal layers of the skin to exact a physiological change. One must be careful to market only beautifying aspect of a product Peptides are an example of an active material They have the ability to penetrate the skin, where they can increase the production of collagen, elastin, and intracellular substances thus improving the appearance of the skin Thousands of cosmetic actives are used to affect the skin in a variety of ways. Some are used to lighten, tighten, and firm the skin Inactive ingredients are considered biologically inert and may serve as: the bases forming the products solution, waxes, emollients, coloring agents, fillers, diluents, preservatives, solvents, lubricants, etc. Most skin care products contain primarily in-active ingredients and add only a few select active ingredients at low concentrations. Our products contain 95%- 99% active ingredients, these are the highest concentrations in the market.
  • 29. Emulsions The majority of creams and lotions are emulsions liquid is dispersed as fine droplets in the other making it homogeneous Homogenized milk is an example of a typical oil-in- water (o/w) emulsion. Using an emulsifier called sodium caseinate The majority of emollients used in personal care and beauty items are fats and oils, also called lipids. Some of the key characteristics required in good emollients are good spreading properties, low toxicity/skin irritation and good oxidative stability.
  • 30. Surfactants Most emulsifiers can be considered surfactants or surface-active agents. These materials are able to reduce the surface tension of water. Example: Washing a greasy pan (fat) is easy with soap, because the soap (surfactant), binds to the oil, and emulsifies with the water, it pulls the grease off of the pan. Fatty acids that are reacted with an emulsifier can form soaps. The process of soap formation is called saponification. The negatively charged stearic acid group is the main emulsifying unit of the soap, giving it the anionic classification. Positively charged emulsifiers are called cationic. Nonionic emulsifiers are often used in skin-care emulsion for their safety and low reactivity. Glycerin, commonly added to cosmetic emulsions for its humectant properties, is the backbone of a class of emulsifiers called Glyceryl esters . Stearic acid is a major component of many of the fats and oils used in beauty treatments, stearate-based emulsifiers are particularly useful. Fatty acids are key components of many cosmetic emulsifiers due their miscibility in a variety of natural and synthetic oils. Esters polyethylene glycol or ethylene glycol are called PEG esters. A PEG ester's solubility is determined by the number of PEG molecules reacted per molecule of acid. In a formulation, are typically used for slip and feel.
  • 31. Moisturizers The main distinction between moisturizers and emollients is their solubility in water. Healthy skin requires moisture. Moisturizers are generally polar materials that are hygroscopic in nature; they hold onto water Glycerin is a very cost-effective ingredient used to help reduce transdermal water loss Sorbitol, sucrose, glucose, and other sugars are also commonly used to hydrate the skin Aloe, which contains a mixture of polysaccharides, carbohydrates, and minerals, is also an excellent moisturizer Moisturizers lay on the surface of the skin and act as a protective barrier. But as a barrier they may block the penetration of other useful (ie. peptides) ingredients that need to reach deeper tissue levels to work
  • 32. Waxes/Thickeners Waxes Waxes are composed primarily of long-chain esters that are solid at room temperature. Common waxes used in cosmetics are beeswax, candelilla, carnauba, polyethylene, emulsifying, and paraffin. Waxes function as structuring agents, adding rigidity and barrier properties. By combining waxes with different properties you can add shine, flexibility, and brittleness Waxes are particularly useful in hand creams and mascara emulsions for their thickening and waterproofing properties. Thickeners By incorporating enough wax into a thin lotion, a thick cream can be formed. Many thickeners are polymers. Cellulose, swells in hot water creating a gel network. Carbopol, a polyacrylic acid, swells when neutralized. Carrageenan, pectin, and locust bean gum are also all examples of cosmetic thickeners
  • 33. Preservatives Most cosmetic products require the addition of preservative to prevent microbial contamination and rancidity Parabens and ester of parabenzoic acid are by far the most commonly used because of their effectiveness against gram-positive bacteria. We do not use this group of preservatives. Phenoxyethanol is used to protect against gram negative strains. The cosmetic chemist will generally employ a mixture of preservatives to protect against different bacterial strains as well as yeasts and molds Antioxidants such as tocopherol (vitamin E) and BHT are also often added to prevent oxidation of sensitive ingredients as well as protect the skin from free- radical damage Shelf life and product preservation is important to consider when the dynamics of ordering , stocking and distribution are being determined Efficacy, safety , environmental acceptance and international compliance are all considered when we select a preservative
  • 34. INCI Names Ingredients are required to be listed on labels in INCI compliant format Ingredients are listed in quantity based descending order; listing the ingredient with highest concentration in the product first INCI stands for the International Nomenclature Of Cosmetic Ingredients an ingredient acceptable in both US and international markets INCI names are a combination of scientific Latin names and the English counterpart. An example of Raspberry Extract would be Rubus Idaeus (Rasberry) Fruit Extract
  • 36. Our Products Contain 12 Peptides 12 Transforming Results Dramatically Reduced Wrinkle Volume Substantially Reduced Wrinkle Depth Substantially Reduced Wrinkle Density Improved Collagen Production Improved Elastin Production Improved Tightening Improved Firmness Dermal Substructure Reinforced Improved Smoothness Improved Tone Tightened Pores Wrinkle Producing Muscle Contractions Inhibited
  • 37. Our Peptides 1. Tripeptide-1 -restores collagen levels substantially. In vitro tests showed collagen 1 and collagen IV synthesis of 128% (collagen I) and 81% (collagen IV) respectively after 15 days. Collagen III tripled, this form of collagen is the most abundant type found in young skin. Tripeptide-1 is a technically advanced ingredient which renews the appearance of critical collagen fibers thus helping the body to rebuild the dermal structure. Study showed a 29% wrinkle depth reduction in 30 days. 2. Palmitoyl Oligo Pentapeptide- It stimulates the production of collagen and fibronectin . Studies have shown collagen synthesis improved 117%, Collagen IV synthesis was improved by 327% and hylauronic acid synthesis increased by 267%. Wrinkle reduction 68%-90%. 3. Dipeptide Diaminobutyroyl Benzylamide Diacetate (Synake) -Mimics a peptide found in the venom of the Temple Viper. It was designed as neuromuscular blocking compound acting at the post-synaptic membrane as a reversible block that prevents acetylcholine from binding to the receptor. One study demonstrated a 52% reduction in forehead wrinkles. 4. Acetyl Hexapeptide-8 (Argireline) -Mimics the N-terminal end of Snap-25 which competes for a position in the SNARE complex. When the SNARE complex is interrupted the vesicle release the neurotransmitters that cause the muscle contractions which form a wrinkle. Studies showed wrinkle depth reduction of 17% in 15 days and 32% in 28 days. 5. Pentapeptide-18 -Inhibits the release of acetylcholine across the neuro synapse. It keeps the neuron in a resting state which may interfere with the muscle contractions that form expression lines and wrinkles. In combination with Argireline studies show it reduces wrinkle depth of 25% to 47% within 28 days.
  • 38. Our Peptides 6. Acetyl Octapeptide-3 (SNAP-8) -Similar to Argireline but 30% more active. Decreases neuronal excitability by destabilizing the SNARE complex. Studies have shown wrinkle depth reduction by 63% in 30 days. 7. Palmitoyl Tripeptide-5 (SynCol) - collagen. Also provides skin firming and moisturizing. In vitro tests in human fibroblasts showed a 119% increase of collagen synthesis compared to the positive standard. 8. Pentapeptide-3 (Vialox) - It acts at the post-synaptic membrane blocking sodium ions. The result is that the muscles that form wrinkles stay relaxed. It inhibits muscle contractions by acting as an competitive antagonist at the AChR receptor. 9. Acetyl Tetrapeptide-5 Won the technology award in cosmetics in 2005. Enhances elasticity of the skin, and improves skin smoothness. It prevents collagen cross links from glycation elasticity loss and the formation of eye bags. It also helps to prevent liquid from accumulating and inhibits vascular permeability. In vivo tests of subjects ages 18-65 resulted in elasticity being improved by 30% in 30 days, puffiness was significantly reduced in 14 days and eye bags were reduced by 70% in 28 days. Dark circles under the eyes were also reduced. 10. Palmitoyl Dipeptide-5 Diaminohydroxybutyrate (syn-taks)- neuromuscular blocking compound acting at the post-synaptic membrane as a reversible block that prevents acetylcholine from binding to the receptor, resulting in no uptake of sodium ions. The effect is that it relaxes facial muscles, smoothes skin, and reduces the appearance of wrinkles. One study demonstrated a 52% reduction in forehead wrinkles.
  • 39. Our Peptides 11. Tripeptide-10 Citrulline Restores collagen levels substantially. In vitro tests showed collagen 1 and collagen IV synthesis of 128% (collagen I) and 81% (collagen IV) respectively after 15 days. Collagen III tripled, this form of collagen is the most abundant type found in young skin. Studies showed a 29% wrinkle depth reduction in 30 days. This peptide maintains a long-lasting collagen function that will help to ensure the appearance of healthy youthful skin. 12. Hexapeptide-10 A peptide that promotes cell adhesion, growth and migration, regenerating the basal lamina. A study showed cell growth increased by 74.6%. In addition to promoting cell adhesion and migration it also helps with the formation of blood vessels, and improves microcirculation. Cell proliferation results in compacted epidermis which provides firmness.
  • 40. High Performance Skin Care 4ce Of Nature provides a revolutionary approach to skincare using a collection of powerful serums to promote youthful skin The line includes 4 highly transformative, anti-wrinkle, peptide enriched medical grade serums that when layered form the treatment component of daily skin care regimen. Other serums in the line target a variety of skin problems experienced producing results far beyond expectations The studies in this slide series helps to demonstrate empirically the efficacy of our products
  • 41. We Built Products With Real Substance 95%-99% of our ingredients in each product are active ingredients Our most powerful ingredients are formulated in concentrations far above the levels found in competitive high-end products Our ingredients are class leading with award winning process technology All ingredients are sourced globally for their intensive performing characteristics
  • 42. Transforming Innovative Ingredients Into Marketable Products The Advantage Is Yours We broke away from conventional thinking to build our products with real substance and stunning results Our highly responsive products can be private labeled to position your organization for growth Our skincare system is powerful enough to build your business by bringing customers back to you monthly, with their friends in tow as referrals wanting to try these products
  • 43. Why We Are Unique? A Clinical Approach To Skincare We took a clinical approach to the design of our products. Our lead formulating chemist is also a biologist She along with our team of physicians approach the formulation process by analyzing the physiologic processes of the body that are compromised She looks at the cellular processes and selects ingredients that act to own repair mechanisms The skin care industry is notorious for selling low concentration, high profile ingredients that are minimally effective and highly profitable We took a different approach. We first consider the problem to be solved and the bodies physiology before ingredients are matched to solve the issue Our ingredients are selected for their targeted functions, as well as the magnitude of their force and ability to correct the issue we identified
  • 44. Secret Formulation Techniques We use closely held secret formulation techniques They took several decades to develop These techniques improve bioavailability, absorption, intensify action, improve penetration, assist to transfer material to the targeted cells, increase the results and shorten time of response These processes are what make us unique and give our products a dramatic performance edge Process engineering and unique ingredient sources makes our products impossible to duplicate without our formula, giving you one of a kind products
  • 45. Bio-Vectored Formulas We use bio-vectors to: Identify the depth of delivery Minimize the molecular size and use bonding to enhance penetration Achieve a high magnitude of impact and results Improve the immediacy of the solution Target the functional component in the transfer of supercharged ingredients to targeted areas
  • 46. Our Highly Skilled Development Team Responsive scientific team with expertise in: Analytical Chemistry Medicine (2 Physicians and a Nurse with Burn and Skin Care Expertise) Biology Microbiology Pharmacology Nutritional Supplementation Cosmeceuticals Process Engineering Aesthetics (Para-medical Aestheticians)
  • 47. ANTI- WRINKLE PEPTIDE SERUM -1oz The Most Targeted Peptide Enriched Product Available Re-awakens the cellular regeneration process Unique blend of eight powerful peptide ingredients Peptides are the most powerful ingredients in the anti-aging wrinkle reducing arsenal Reduces wrinkle volume, depth and density Encourages the body to rebuild collagen and elastin for visibly younger skin Process engineering and unique ingredient sources makes this product almost impossible to duplicate without our formula, giving you a one of a kind product
  • 48. PEPTIDE SERUM INGREDIENTS Tripeptide-1- patented active peptide that helps the body substantially restore collagen levels. Subjects studied from ages 35 to 55 showed a 29% wrinkle depth reduction in 30 days Palmitoyl Oligo Pentapeptide - only a limited number of labs have access to this peptide due to patent restrictions. Stimulates the production of collagen and fibronectin promoting extracellular matrix renewal and cell proliferation. An in vivo (human based) study resulted in: the surface area of the deep wrinkles decreases by 68%, and in some cases was reduced by as much as 90% " the density of the main furrows: decreased by 47% " the area of the moderate wrinkles: decreased by 51% " the mean area of the main wrinkle: decreased by 22% Stimulated the synthesis of the extra-cellular Matrix in vitro and ex vivo to very different extents: Collagen I : +117% Collagen IV : +327% It also stimulates the production of glycosaminoglycans: +267%.
  • 49. Palmitoyl Oligo Pentapeptide Peptide #2 Peptide #2, (one of twelve peptides used in our products) is a fragment of the C-terminal portion of collagen I synthesis of collagen I, collagen III and fibronectin It has a more marked impact on low-density cultures of fibroblasts than on higher density, confluent cultures This is relevant because it is closer to aging skin, which has a reduced population of fibroblasts
  • 50. Deep Wrinkles Reduced By 68%-90% The surface area occupied by deep wrinkles was reduced by a mean of 68% over 6 months and in some cases was reduced by as much as 90% The density of the main furrows: decreased by 47% The area of the moderate wrinkles: decreased by 51% The mean area of the main wrinkle: decreased by 22% The concentration of this peptide in our products ranges between 8-16 times greater than the concentration used in this study
  • 51. Significant Reduction In Wrinkles Before Peptide #2 Use 6 Months After Peptide Use
  • 52. Focus Ingredients Dipeptide Diaminobutyroyl Benzylamide Diacetate (Synake) a neurotrasmitter blocker, relaxes facial muscles, smoothes skin, and reduces the appearance of wrinkles. One study demonstrated a 52% reduction in forehead wrinkles. Acetyl Hexapeptide-8 (Argireline) - reduces the appearance of the depth of wrinkles caused by facial expressions. Studies showed wrinkle depth reduction of 17% in 15 days and 32% in 28 days. Pentapeptide-18 - interferes with the formation of expression wrinkles. In combination with Argireline studies show it reduces wrinkle depth of 25% to 47% with in 28 days. Acetyl Octapeptide-3 (SNAP-8) - reduces wrinkle depth from the expression areas of the face . Studies have shown wrinkle depth reduction by 63% in 30 days. Palmitoyl Tripeptide-5 (SynCol) - product collagen. Pentapeptide-3 (Vialox) - peptide that offers intensive wrinkle care. It reduces expression line wrinkles and relaxes muscles.
  • 53. Acetyl Hexapeptide-8 (Argireline) Peptide #4 Peptide #4 was designed to reduce wrinkle depth caused by facial expressions (forehead and eyes) It is a neuro-transmitter blocking peptide It mimics the N-terminal end of Snap-25 which competes for a position in the SNARE complex neurotransmitters that cause the muscle contractions which form a wrinkle. Studies showed wrinkle depth reduction from use of this peptide, of 17% in 15 days and 32% in 28 days. Silicone imprints were made for this study and measured by confocal profilometry
  • 54. How It Works Muscles are contracted when they receive neurotransmitters released from a nerve cell in a process known as neuronal exocytosis The neurotransmitter involved is acetylcholine and it is released from a vesicle into the synapse The process involves several proteins, channels and vesicles The SNARE protein complex is essential for neurotransmitter release at the synapsis and mediates the final steps of exocytosis It is a complex formed by three proteins: VAMP, Syntaxin and SNAP-25 This complex is like a cellular hook that captures vesicles (a process called docking) and brings them close to the membrane to enable their fusion
  • 55. How It Works Neuro-transmitter acetylcholine and it is released from a vesicle into the synapse The SNARE protein complex is formed by 3 proteins, VAMP, Syntaxin, and SNAP-25 and it is essential for neuro-transmitter release at the synapse and mediates the final steps of exocytosis Acting as cellular hook it captures vesicles and brings them close to the membrane to enable fusion
  • 57. Botlinum Toxin A Botulinum Toxin A paralyses the muscle by selectively blocking acetylcholine release at the neuromuscular junction BoNT-A cleaves the protein SNAP-25 irreversibly, and therefore the SNARE complex cannot assemble The nerve signal cannot be relayed, the muscle cannot contract and it is paralyzed.
  • 58. Destabilized SNARE Complex, Peptide #4 If the SNARE complex is slightly destabilized, the vesicle cannot release neurotransmitters. As a consequence, muscle contraction is attenuated and the muscle is relaxed Peptide #4 is a mimic of the N-terminal end of SNAP-25 and it competes with the natural protein for a position in the SNARE complex, so it destabilizes its formation, without breaking any of its components
  • 59. In Vitro Efficacy Inhibition of glutamate release at mM concentrations is a clear indicator of the potent anti-expression wrinkle activity of the peptide. Inhibition of glutamate release by depolarized neuron is a validated cell assay for measuring the potential activity of compounds on the inhibition of neuronal exocytosis. Untreated neuron cultures were used as a negative control and cultures treated with Botulinum Toxin A (BoNT- A) were used as a positive control
  • 60. Two In-Vitro Tests Related To The Formation Of Wrinkles Reduction in the depth of wrinkles up to 17% after 15 days with 10% Peptide # 4 solution The depth of the furrow decreased a maximum value of 32% in 28 days with a cream containing 5% Peptide #4 solution. The concentration in our formula is much higher
  • 61. Another Study This peptide reduces the severity of wrinkles around the eyes, up to 17% after 15 days of treatment and up to 27% after 30 days of treatment Objective: To determine the effectiveness of the peptide #4 cream in reducing the severity of wrinkles
  • 62. Reduced wrinkle depth up to 27% in 30 days
  • 63. Volunteer nº5 (38 years) Base Peptide 4
  • 65. Volunteer nº3 (54years) Video Sequence
  • 66. Volunteer nº7 (45 years) Video Sequence
  • 67. Dipeptide Diaminobutyroyl Benzylamide Diacetate (Synake) A neuro-transmitter blocking Peptide A small peptide that mimics the activity of a polypeptide found in the venom of a Viper Capable of reducing mimic wrinkles by inhibiting contractions Reduced forehead wrinkles by 52%
  • 68. Ra: average roughness Rt: maximum difference between the highest peak and the deepest furrows Rz: mean value of these different maxima Study On Smoothing A decrease of the Ra expresses a smoothed relief A decrease of the Rt and Rz expresses a decrease of And Anti-Wrinkle wrinkle depth Effect Of Peptide # 3
  • 69. Wrinkles Decrease 52% On The Forehead Measurements on Volunteer #29 showed that Peptide #3 was able to reduce forehead wrinkles by up to 52% In vitro measurements showed that Peptide #3 (at a concentration of 0.5mM) was able to reduce the frequency of contractions of innervated muscle cells by 82% (p<0.05) after 2 hours of treatment and anti-wrinkle effect on this area
  • 70. Wrinkle Height Profile Using the PRIMOS® technique, parallel stripe patterns are projected on the sample with successive phase shift. The analysis of fringe deformations provided a qualitative and quantitative evaluation of each height profile
  • 71. Acetyl Octapeptide-3 (SNAP-8) Peptide #6 A wrinkle reducing peptide that is similar to Argireline but 30% more active. It reduces wrinkle depth from the expression areas of the face such as the forehead and eyes. It decreases neuronal excitability by destabilizing the SNARE complex. Studies have shown wrinkle depth reduction by 63% in 30 days.
  • 72. Inhibition Of Snare Complex Formation Demonstrates the blocking of SNARE complex formation. The lower the SNARE complex in vitro, the higher the efficacy of the anti-wrinkle cream. Evaluated the antagonistic competitive efficacy of the peptide patterned after SNAP-25 N-Terminal domain compared to native SNAP-25(positive control). Peptide #6 has the capacity to assemble with syntaxin and synaptobrevin forming the SNARE complex, which was measured. Heat and consequent thermal decomposition was the negative control
  • 73. Modulation Of Glutamate Release In A Neuron Cell Culture Peptide #6 Peptide #6 Glutamate is the most excitatory abundant neurotransmiter in the nervous system. The release of glutamate in a primary cell culture of neurons was measured to compare the in vitro activitiy of Peptide 6 and Botulinum Toxin A (positive control) Peptide #6 inhibits glutamate release in a dose-dependent manner
  • 74. 63% Reduction Value Of Wrinkle Depth With Peptide #6 Skin topography analyses were performed to measure the effectiveness of a cream containing 10% Peptide #6 Silicon imprints were obtained from around the eyes of 17 women volunteers pre-test and after the 28 day treatment. Analyses of imprints were performed by confocal profilometry
  • 75. Bonnie After Using The Peptide Serum Day 0 Week 3
  • 76. Stem Cell Serum Using state of art technology to culture plant stem cells Based on high-tech bioreactor plant cell culture technology, that was awarded the Innovation Award in 2008 First stem cell ingredient is from a rare apple, known for its longevity A study with our first ingredient with subjects between the ages of 37-64, showed a significant and visible decrease in wrinkle depth for 100% of the subjects by the 28 days. Study results showed that the CFE (colony-forming efficiency) was stimulated by 92% in the presence of 0.04% of the stem cell extract. This clearly showed an improved maintenance of the stem cell characteristics of epidermal stem cells. Second plant stem cell ingredient is from a rare Gamay grape ,which has extremely high anthocyanins, this ingredient fights photo-aging and delays cell death Study results showed this stem cell extract to strongly increase CFE: the CFE was stimulated by almost 80% Clearly showing that it helps the epidermal stem cells maintain their stem cell characteristics.
  • 77. Why Use Plant Stem Cells Epidermal stem cells rejuvenate and promote the balance of cells in the skin and help to regenerate damaged tissue. Aging reduces the number of stem cells in the skin and diminishes their ability to repair the skin. Plant stem cells contain specific epigenetic factors that help to maintain the regeneration capacity of stem cells in the skin. The result is a remarkable improvement in the appearance of the skin as well as a reduction in wrinkles, and protection against oxidative stress.
  • 78. Focus Ingredients Malus Domestica Fruit Cell Culture - Awarded the Innovation Award in 2008. It uses a liposomal delivery system and is based on plant stem cells from an endangered fruit(apple) that is known for its longevity. Studies have demonstrated its remarkable age delaying and anti-wrinkle effects in humans. Palmitoyl Oligo Pentapeptide - Promotes collagen helps to improve the visible signs of aging. Vitis Vinifera (Grape) Fruit Cell Extract - Plant stem cells contain specific components, called epigenetic factors. They regulate the activity and the function of the cell. These plant stem cells improve the vitality of skin stem cells, and protect them against negative environmental influences
  • 79. Improvement Using Apple Stem Cell Before (day 0) of use of our Apple Stem Cell After (day 28)
  • 80. TIGHTENING SERUM- 1 oz Reduce The Appearance Of Loose Skin And Enlarged Pores Contains peptides designed to help you look younger by increasing the elastin and collagen in your skin Reduces the appearance of loose skin and improves the skins resilience Improves cell proliferation resulting in a more compacted epidermis which provides firmness Provides a noticeable tightening effect, strengthens connective tissue, and provides protection against oxidative stress.
  • 81. Focus Ingredients Tripeptide-10 Citrulline - A peptide that substantially restores collagen levels. Showed a 29% wrinkle depth reduction in 30 days. This peptide maintains a long-lasting collagen function. Pullulan - An anti-oxidant that also helps to retain moisture. Hexapeptide-10 - A peptide that promotes cell adhesion, growth and migration, regenerating the basal lamina. Tests have been carried out to quantify the increase in cellular adhesion of keratinocytes and fibroblasts. A study showed cell growth increased by 74.6%. Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine (syn-taks) - It helps to restore the structural integrity of the skin, reducing wrinkles, and improving tone. Palmitoyl Dipeptide-5 Diaminohydroxybutyrate (syn-taks) - It helps to restore the structural integrity of the skin, reducing wrinkles, and improving tone. Enteromorpha Compressa Extract - An edible form of green algae that produces a large array of bioactive compounds found useful in the treatment of inflammation, allergies and bacterial and viral infections. Theobroma Cacao(Cocoa) Extract Provides anti-oxidant and anti-stress effects for skin preparations. Acts as a skin balancer and energizer reducing cell degeneration and protecting the skin from cell damage.
  • 82. PEPTIDE EYE SERUM-! oz Award Winning Ingredients Used In This Powerful Peptide Serum Exciting powerful eye serum using award winning ingredients. This product provides dramatic reductions in baggy eyes, dark circles, fine lines and wrinkles. Returning the skin to a much more youthful state.
  • 83. Focus Ingredients Acetyl Tetrapeptide-5 - Won the technology award in cosmetics in 2005. In vivo tests of subjects ages 18-65 resulted in elasticity being improved by 30% in 30 days, puffiness was significantly reduced in 14 days and eye bags were reduced by 70% in 28 days. Dark circles under the eyes were also reduced. Acetyl Octapeptide-3 (SNAP-8) It reduces wrinkle depth from the expression areas of the face such as the forehead and eyes. It decreases neuronal excitability by destabilizing the SNARE complex. Studies have shown wrinkle depth reduction by 63% in 30 days Dipeptide Diaminobutyroyl Benzylamide Diacetate (Synake) - A wrinkle reducing active peptide that mimics a peptide found in the venom of the Temple Viper. It was designed as neuromuscular blocking compound acting at the post-synaptic membrane One study demonstrated a 52% reduction in forehead wrinkles.
  • 84. EYE LASH LENGTHENER 10ml We Broke From Conventional Thinking When This Product Was Designed Unparalleled combination of class leading formulation processes and performance based ingredients Uses Keratinocyte Growth Factor partnered with a variety of powerful ingredients that benefit the follicles ability to add new hair. We set the stage by improving the environment for growth and then added the trigger that makes it happen.
  • 85. Focus Ingredients L-Acetyl Carnitine - Reactivates the hair follicles. Transfers fatty acids to the mitochondria to be used as energy and to enhance active metabolism needed for cellular repair. Niacinamide - An anti-inflammatory and vasodilator. It stimulates collagen and acts as an anti-oxidant. It reduces inflammation. Soy Isoflavones - Helps preserve elasticity limiting the breakage of hair. Saw Palmetto Extract - Thought to block cell receptor sites required to absorb DHT. May improve hair growth, maintains healthy hair and helps to reverse hair loss. Keratin - Primary constituent of hair it wraps the hair follicle with a keratin bond that protects and strengthens the hair shaft. Nettle Extract - Partially blocks 2 enzymes, 5a-reductase, which makes dihydrotestosterone (DHT) and aromatase enzyme. These enzymes are thought to block hair growth. Hexanoyl Dipeptide-3 Norleucine Acetate: - A peptide that activates follicle regeneration.
  • 86. Focus Ingredients Lecithin- A natural emulsifier and lubricant. It also protects cell follicles from oxidation and breakdown. L-Arginine - An amino acid that may bring oxygen to the tissue. It may act on the follicle by promoting the formation of L-proline, an amino acid that is essential to the synthesis of collagen. It is thought to play a role in cell division. L-Glutamine - An amino acid that helps with cell rejuvenation. Acts as an eye tissue nutrient. Zinc - Benefits cellular growth and appears to limit DHT production. It helps with absorption of vitamins and proteins that are necessary for hair growth and maintenance. Keratinocyte Growth Factor (KGF) - A growth factor that promotes hair growth, it is synthesized by fibroblasts. A complex growth factor it contains an 160 amino acid chain that stimulates cell replication. This is made specifically for our product. Superoxide Dismutase - An enzyme that prevents oxidative stress and enhances antioxidant balance. SOD is found in the dermis and epidermis and is important in the production building new cells.
  • 87. LIGHTENING SERUM 1 oz Revolutionary Serum Significantly Lightens And Reduces The Appearance Of Skin Discoloration An aesthetic treatment that significantly reduces the appearance of skin discoloration and lighten and brightens the appearance of the skin. Each individual responds differently to ingredients, we approached this issue by using ten distinctly different skin lightening ingredients. Each ingredient operates in a slightly different way to ensure that the outcome will be what you expect.
  • 88. Focus Ingredients Diaminopropionoyl Tripeptide-33 - A peptide that reduces the appearance of photo-aging. It promotes the DNA repair systems capacity, and provides the skin protection from aging. Arbutin - Arbutin has a depigmenting effect on the skin. Increases cutaneous luminosity, cutaneous smoothness, with a significant reduction of cutaneous tint, and cutaneous dyschromia. Inhibits the tyrosinase enzyme and has been documented by in vitro studies to have an enzymatic inhibition level of 56%. Kojic Acid - An effective skin lightener, inhibits melanin production, helps to balance skin tones, fading dark spots and freckles caused by sun exposure, aging, and cutaneaous hyper-pigmentation. Licorice Root - A skin whitener, anti-inflammatory, anti-microbial and anti-oxidant. Magnesium Ascorbyl Phosphate - It significantly affects the appearance of skin lightening acting to inhibit tyrosinase to reduce the formation of melanin. It also promotes collagen synthesis.
  • 89. Focus Ingredients Bellis Perennis (Daisy) Flower Extract - Highly efficient natural skin lightener by influencing melanin formation. An in vitro study done in the Philippines showed a reduction of tyrosinase and tyrosinase activity resulting in a significant lightening effect. Diacetyl-Boldine - A skin lightener, was shown to be 30 times more effective than kojic acid. In vitro tests showed it inhibited the activity of tyrosinase by 56%. A study of Asian subjects showed skin lightening improved by 71%, hyper-pigmented areas decreased by 54%, complexion was viewed as 65% move even, and 74% more radiant. A study of Caucasian subjects showed a 23% reduction in age spots. It provides the skin with an even, luminous and mat complexion. 1-aminoethylphosphinic acid - Used as a skin lightener to reduce age spots. Acts different from tyrosinase inhibitors, it slows down melanogenesis providing a whitening effect by decreasing melanin systhesis at the DOPA-Chrome level Dimethylmethoxy Chromanyl Palmitate - Provides considerable skin lightening. A study of Asian women ages 18-46 showed a 37% inhibition of tyrosinase activity, it stopped endogenous tyrosinase activity by 43% and was found to have a better di- pigmenting effect than Kojic acid.
  • 90. CELLULITE CREAM 5 oz Finally A Solution That Actually Works This intensely effective approach to lustrous, youthful, smooth skin, reduces the appearance of cellulite. A Brazilian study of 99 women showed more than 88% experienced a decreased circumference their thighs and arms 68% saw an additional reduction of their hip size when the caffeine ingredient was analyzed. Pseudoalteromonas Ferment Extract study showed 128% increase in collagen 1 within 15 days 81% increase in type IV collagen
  • 91. Focus Ingredients Lecithin - May reduce the accumulation of fluids, reduce inflammation and improve circulation. Helps the body improve the support structures under skin to keep cellulite from showing through. Caffeine - Vasoconstrictor, reduces fluid retention and may improve fat metabolism. Butcherbroom (Ruscus Aculatus) Root Extract - Decreases excess fluids, anti- inflammatory. Tea-Hydroiodide - Is a skin conditioning agent. Ivy (Hedera Helix) Extract - Tones, tightens and helps reduce build up of waste products in tissue. Carnitine - A naturally occurring amino acid supports the transport long chair fatty acids to the mitochondria where it is used for energy. Thought to improve appearance of dimpled skin. Tripeptide-1 - A patented peptide that acts as a skin conditioning agent. Panthenol - Provitamin B5 has the effect of filling in areas and stretching the skin.
  • 92. Focus Ingredients Marrubium Vulgare Extract - An anti-inflammatory that assists in absorption. Pseudoalteromonas Ferment Extract - A glycoprotein found at the bottom of a glacier in Antartica, it is thought to increase elastin and collagen. One study showed a 128% increase in collagen 1 within 15 days and a 81% increase in type IV collagen. Acetyl Tetrapeptide-5 - A peptide that reduces edema in tissue. Pentapeptide-18 - A neuropeptide that helps to relax muscles and tighten the skin. Rucus Aculeatus Root Extract - Improves microcirculation in the skin, and capillary permeability. Citrus Medica Limonum Peel Extract - Benefits circulation and helps improve blood flow. Solidago Virgaurea Extract - Improves circulation, contracts tissue, reduces fluids. Astragalus Membranaceus Root Extract - Benefits micro-circulation, firms and smoothes the skin and helps to reduce the appearance of imperfections. Ilex Paraguariensis Leaf Extract(Yerba Mate) - Has a relaxing effect on muscle tissue, burns fat. Cameilia Oleifera Extract(Green Tea) - Rich in anti-oxidants and anti-inflammatory properties. Cola Acuminata Seed Extract - Provides the stimulating and fluid draining effects of caffeine. Improves texture on uneven dimpled skin. Japanese Pepper Extract: - A pepper that results in a hot or tingling sensation to the skin. It is an anti- oxidant that also benefits microcirculation. Anti-inflammatory.
  • 93. FACIAL/BODY HAIR INHIBITOR 1 oz Dramatically Reduce The Appearance Of Unsightly Hair Hair growth cycles can take 3-4 months with 80% of your hair in a growth cycle at any one time. Most cultures dictate the aesthetic level of hair for both men and women and social acceptance is affected for those who violate those norms. It effectively helps to dramatically reduce the appearance of unsightly hair A study on one of our key ingredients showed a decrease of 30% in hair length and a 16% reduction in density within 60 days.
  • 94. Focus Ingredients Larrea Diviaricata Extract - A hair growth inhibitor that also has anti-oxidant and anti-microbal properties. Lauryl Isoquinolinium Bromide - A major hair growth inhibiting ingredient. It decreases the length and density of hair, reduces the need for shaving or depilation. It targets the hair follicle cells and decreases new hair formation. One study showed a decrease of 30% in hair length and a 16% reduction in density within 60 days. Pseudoalteromanoas Ferment Extract - It maintains natural bio-protective properties and promotes keratinocyte growth and fibroblast adhesion for a skin regenerating effect. A study showed increased collagen I synthesis by 81% after 7 days and 128% after 15 days and increased collagen IV synthesis 36% after 7 days and 81% after 15 days. Subtilisin - A keratinolytic protease that invades the hair structure and causes proteolytic cleavage which reduces intercellular adhesion and reduces hair growth. It also diminishes the size of hair follicles and hair shafts. Palmatine - Slows mitosis and therefore reduces hair growth.
  • 95. New Products Roll Off Wrinkles A strong peptide formula that comes in bottle with a roller ball. It can be carried in your pocket or purse and used throughout the day. It is particularly designed to eliminate the more difficult wrinkles Anti-Oxidant Serum A serum loaded with anti-oxidants that will protect the skin from free radical scavengers, nourish and revitalize it Telomer Protect Serum - The discovery of telomeres won the 2009 Nobel Prize in youthful cell function. Every time your cells divide, your telomeres shorten. When your telomeres become too short, cell division stops and your cells can no long divide to build new cells. This product helps maintain telomeres and extend the lifespan of your skin cells. up your sagging skin Inside Out Beauty Supplement Designed using three proprietary blends of the ingredients. The first is a powerful blend of amino acids which encourages the body to produce Human Growth Hormone. This hormone declines with aging and that loss results in a loss of energy, stamina, strength, muscle tone and skin tone, thickness and wrinkle formation. This blend can dramatically assist the body to achieve the vigor and characteristics of a more youthful state. The other two blends focus on adding anti- oxidants to the body to improve both health and beauty.
  • 97. Why We Are Unique We use the highest quality ingredients We formulate using high concentrations of the most potent ingredients We use semi-manual encapsulation processes to eliminate the need for excipents We perform vendor audits, and all ingredients are tested for purity, potency, authentication We participate in an extensive audit by an outside auditing company We use the most cutting edge advancements to aging in recent history An unparalleled approach to beauty and wellness 95%-99% of our ingredients in each product are active ingredients Our formulation team includes physicians Our formulations use clinical strengths of medical grade ingredients All products are manufactured in house in our fully accredited manufacturing plant
  • 98. Appetite Suppressant/Thermogenic This appetite suppressant works by Diminishing appetite Increases the sensation of fullness Improves mood Helps to develop a perceived sense of happiness Unlike other supplements this product approaches appetite suppression from many angles, and gives the body several opportunities to feel satiety. It acts as a thermogenic burning of fat. It is caffeine, and ephedra free. It controls appetite during times of boredom or emotional distress.
  • 99. WEIGHT LOSS CARBOHYDRATE CONTROL - 180 caps The Help You Need To Control Carbs Helps to break the vicious weight gain cycle and control carbohydrate cravings. Helps reduce the absorption of starch Breaks down carbs into absorbable sugars Helps the body better regulate glucose and insulin Improves pancreatic function by mediating insulin release Helps the body better use calories and metabolize glucose Reduces carbohydrate cravings Stimulates the brain to feel satisfied and full
  • 100. WEIGHT LOSS FAT BURNER (LIPOTROPIC) - 60 caps Power Up Your Ability To Burn Away Fat This supplement helps to: Control appetite and improve mood Breakdowns fat and converts it to energy Removes and metabolizes excess fat from the liver its effect on fat storage formation on arterial walls
  • 101. NATURAL HAPPINESS 60 caps Renew Your Sense Of Joy, Re-energize Your Life A non sedating formula that helps maintain and elevate mood levels Combats fatigue Increases energy levels and improves malaise Helps minimize depression and relieve tension, irritability, stress and anxiety Improves memory
  • 102. LIVER SUPPORT 180 caps Is Your Liver Working Overtime? What Are You Doing To Protect It? Aids in liver detoxification Improves digestion Enhances bile production and flow Assists in neutralizing and eliminating toxins, provides anti- oxidant benefits Helps protect the liver from damage and supports its optimal functioning
  • 103. MENOPAUSE SYMPTOM RELIEF 60 caps Live Comfortably As Menopause Approaches Improves menopause symptoms Helps regulate mood swings Helps regulate hormonal swings Reduces hot flashes and night sweats Minimizes weight gain Improves bladder incontinence and overactive bladder
  • 104. JOINT SUPPORT 480 grams Reduce Pain, Swelling, Tenderness And Stiffness Helps build synovial fluid and cartilage Improves mobility and reduces discomfort Improves health and function of cartilage Reduces pain, swelling, tenderness and stiffness Improves athletic recovery
  • 105. MUSCLE CRAMP OIL 4oz Stop Painful Sudden Forceful Muscle Cramps Helps restore magnesium levels in the body Helpful to athletic recovery Helps relieve aches, pain, muscle cramps, and stiffness Helps maintain muscle function Calms nerves Supports restful sleep Highly absorbable without GI side effects common with oral version and acts quickly
  • 106. Q IMMUNE 120 caps An Unprecedented Approach To Immune Support The discovery of the biologic importance of our key ingredient Germanium has been touted as a landmark development in the field of nutritional and metabolic medicine Dramatically improves the efficiency of oxygen utilization at a cellular level Each atom of germanium is bonded to three atoms of oxygen, making it an efficient carrier of oxygen, it is believed oxygen cannot be properly metabolized by cancer cells Powerful regulator of the immune system, activating an under-active system and suppressing over-activity when necessary Our unique proprietary engineered blending process transforms this combination of ingredients and dramatically enhances their effectiveness bioavailability provides a compounding effect with the supporting ingredients
  • 107. 4ce Of Nature and one of a kind. technology, and process engineering as we transform our secret processes and a set of incredibly responsive ingredients, into highly responsive products. ever experienced Producing rapid and stunning changes to the skin Transforming tired, aged, wrinkled skin into vibrant youthful restored skin Protecting younger skin from the ravages of aging
  • 108. 4ce Of Nature Using highly concentrated peptide enriched formulas our products produce astounding results. Nothing currently on the market comes close to our products performance Process engineering offers our products a unique edge and protects against competitors attempts at duplication Small molecular sizes allow deep penetration Unique delivery systems maximize absorption Careful PH balancing help our products to penetrate deeper and respond faster