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Hematopoietic System
Kristine Krafts, M.D.
Hematopoietic System Lecture Objectives
• Describe the developmental stages of erythropoiesis.
• Describe the developmental stages of granulopoiesis.
• Describe the differences between red marrow and
yellow marrow.
• List the components of bone marrow stroma.
• Explain the concept of colony forming units (CFUs).
Hematopoietic System Lecture Outline
• Introduction
• Erythrocytes
• Platelets
• Leukocytes
• Granulocytes
• Agranulocytes
Hematopoietic System Lecture Outline
• Introduction
Hematopoietic Tissue
Specialized connective tissue.
Derived from mesenchyme.
Function: produce new blood cells and remove
old ones.
Two types of hematopoietic tissue
• Myeloid tissue (in bone marrow):
produces everything except lymphocytes
• Lymphoid tissue (in lymph nodes, spleen):
produces lymphocytes (different lecture!)
Prenatal Hematopoiesis
Myeloid Tissue (Bone Marrow)
• Bone marrow in adults is found between
trabeculae of cancellous (spongy) bone and in
the marrow canal of long bones.
• Red (hematopoietic) bone marrow is found in
flat bones of skull, vertebrae, ribs, pelvis, and
ends of long bones.
• Yellow bone marrow is found in long bone
diaphyses. It is composed of fibrous CT, adipose
tissue (yellow color), nerves, and blood vessels.
Components of Bone Marrow
• Stroma: a connective tissue network which
supports the blood-forming cells.
• Sinusoids: wide, thin-walled vessels with
discontinuous endothelial cells which allow
new blood cells to gain access to the
bloodstream.
• Developing blood cells: red cell precursors,
white cell precursors (except lymphoid
precursors), and megakaryocytes.
Stroma
Cells
• Fibroblasts
• Macrophages
• Adipocytes (fat cells)
• Osteogenic cells
• Endothelial cells
Fibers
• Type I collagen fibers
• Type III collagen
(reticular) fibers
Bone marrow is present between trabeculae of
spongy (cancellous) bones
Bone marrow: trabeculae, hematopoietic tissue and sinusoids
Hematopoiesis
Statement of Purpose:
The purpose of the International Academy of Classical Homeopathy is the
professional education of medical doctors, medical students and health practitioners
in order to become effective Classical Homeopaths, according to the principles of Dr.
Samuel Hahnemann.
Mission Statement: As a paradigm of distinguished and superlative education in genuine
classical Hahnemannian homeopathy, the International Academy of Classical Homeopathy
advocates premier excellence in instruction to establish and foster leaders in the homeopathic
community who are dedicated to this scientific art of healing in order to:
•Become practicing certified classical homeopaths in North America,
•Gently restore the sick to health and alleviate the suffering of others,
•Establish respectful and compassionate standards for patient treatment and care,
•Promote the science of homeopathy,
•Contribute to research in the efficacy of classical homeopathy,
•Motivate others to study, practice, research, and teach the classical art of homeopathy,
•Facilitate the advancement of homeopathic education within our associated alternative and
conventional medical communities.
Vision:​
• The International Academy of Classical Homeopathy is an
institution for students who seek truth and knowledge in the art of
true healing with classical homeopathy in order to become
nationally certified practitioners who will continue to change the
landscape of homeopathic practice and the future of health care in
North America and around the world. Our vision is for the
International Academy of Classical Homeopathy to be the principal
foundation that promotes and protects the original instruction of
Hahnemannian Classical Homeopathy – in its purest form. We
intend to unite with more Universities and other academic
institutions, to organize fundamental international meetings, to
encourage high-quality cutting-edge research, to inform doctors
and patients about the immense curative potential of Classical
Homeopathy, and to honor the best research projects as well as the
best homeopaths from all over the world.
Values:
• Nurturing the Student Homeopath and Continuous
Enlightenment of the Practitioner through Immersion
Methodology
• Commitment to the International Perpetuation of Classical
Homeopathy in terms of Research, Legislation, Public
Awareness and Education
• Complete and Whole Restoration of Health and Wellness to
the Sick – To Cure as it is Termed
• Respect for All Humanity without Ego and without Bias

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Homeopath Medicine

  • 2. Hematopoietic System Lecture Objectives • Describe the developmental stages of erythropoiesis. • Describe the developmental stages of granulopoiesis. • Describe the differences between red marrow and yellow marrow. • List the components of bone marrow stroma. • Explain the concept of colony forming units (CFUs).
  • 3. Hematopoietic System Lecture Outline • Introduction • Erythrocytes • Platelets • Leukocytes • Granulocytes • Agranulocytes
  • 4. Hematopoietic System Lecture Outline • Introduction
  • 5. Hematopoietic Tissue Specialized connective tissue. Derived from mesenchyme. Function: produce new blood cells and remove old ones. Two types of hematopoietic tissue • Myeloid tissue (in bone marrow): produces everything except lymphocytes • Lymphoid tissue (in lymph nodes, spleen): produces lymphocytes (different lecture!)
  • 7. Myeloid Tissue (Bone Marrow) • Bone marrow in adults is found between trabeculae of cancellous (spongy) bone and in the marrow canal of long bones. • Red (hematopoietic) bone marrow is found in flat bones of skull, vertebrae, ribs, pelvis, and ends of long bones. • Yellow bone marrow is found in long bone diaphyses. It is composed of fibrous CT, adipose tissue (yellow color), nerves, and blood vessels.
  • 8. Components of Bone Marrow • Stroma: a connective tissue network which supports the blood-forming cells. • Sinusoids: wide, thin-walled vessels with discontinuous endothelial cells which allow new blood cells to gain access to the bloodstream. • Developing blood cells: red cell precursors, white cell precursors (except lymphoid precursors), and megakaryocytes.
  • 9. Stroma Cells • Fibroblasts • Macrophages • Adipocytes (fat cells) • Osteogenic cells • Endothelial cells Fibers • Type I collagen fibers • Type III collagen (reticular) fibers
  • 10. Bone marrow is present between trabeculae of spongy (cancellous) bones
  • 11. Bone marrow: trabeculae, hematopoietic tissue and sinusoids
  • 13. Statement of Purpose: The purpose of the International Academy of Classical Homeopathy is the professional education of medical doctors, medical students and health practitioners in order to become effective Classical Homeopaths, according to the principles of Dr. Samuel Hahnemann. Mission Statement: As a paradigm of distinguished and superlative education in genuine classical Hahnemannian homeopathy, the International Academy of Classical Homeopathy advocates premier excellence in instruction to establish and foster leaders in the homeopathic community who are dedicated to this scientific art of healing in order to: •Become practicing certified classical homeopaths in North America, •Gently restore the sick to health and alleviate the suffering of others, •Establish respectful and compassionate standards for patient treatment and care, •Promote the science of homeopathy, •Contribute to research in the efficacy of classical homeopathy, •Motivate others to study, practice, research, and teach the classical art of homeopathy, •Facilitate the advancement of homeopathic education within our associated alternative and conventional medical communities.
  • 14. Vision:​ • The International Academy of Classical Homeopathy is an institution for students who seek truth and knowledge in the art of true healing with classical homeopathy in order to become nationally certified practitioners who will continue to change the landscape of homeopathic practice and the future of health care in North America and around the world. Our vision is for the International Academy of Classical Homeopathy to be the principal foundation that promotes and protects the original instruction of Hahnemannian Classical Homeopathy – in its purest form. We intend to unite with more Universities and other academic institutions, to organize fundamental international meetings, to encourage high-quality cutting-edge research, to inform doctors and patients about the immense curative potential of Classical Homeopathy, and to honor the best research projects as well as the best homeopaths from all over the world.
  • 15. Values: • Nurturing the Student Homeopath and Continuous Enlightenment of the Practitioner through Immersion Methodology • Commitment to the International Perpetuation of Classical Homeopathy in terms of Research, Legislation, Public Awareness and Education • Complete and Whole Restoration of Health and Wellness to the Sick – To Cure as it is Termed • Respect for All Humanity without Ego and without Bias