2. PRETEST
1. Name some invasive measures and noninvasive ways
of hemodynamic monitoring
2.Name some advanced hemodynamic monitoring
parameters
3.What test you do before arterial line insertion
4.Name a site contraindicated for arterial line
5.Normal mixed venous oxygen saturation
6. What is oxygen delivery and oxygen consumption
7.what is passive leg raising test
3. OBJECTIVES
HEMODYNAMICS
What is it?
Why is it important to monitor?
Whom to include?
How to measure?
Its merits and demerits.
4. HEMODYNAMICS- DEFINITION
the forces which circulate blood through the
body.
used to describe the intravascular pressure and
flow that occurs when the heart muscle contracts
and pumps blood throughout the body.
5. Hemodynamic Monitoring
measurement of pressure, flow and oxygenation of blood
within the cardiovascular system.
OR
Using invasive technology to provide quantitative
information about vascular capacity, blood volume, pump
effectiveness and tissue perfusion.
OR
measurement and interpretation of biological systems that
describes the performance of cardiovascular system
7. PURPOSE OF MONITORING
Circulatory shock is an important cause of pediatric
morbidity and mortality.
Early recognition of inadequate tissue perfusion &
oxygenation followed by prompt treatment most important.
In pediatric circulatory shock, cardiac output (CO) & BP can
be low, normal, or high.
Physical examination, poorly reflects CO, preload status, or need
for fluid or other hemodynamic interventions.
BP & HR often do not reflect blood flow
8. Potential clinical value of 4 advanced hemodynamic
monitoring technologies
CO monitoring
Venous oximetry
Fluid responsiveness
Lung water
9. DO2 = SaO2 × Hb × CO
After load
Preload SV × HR
Contractility
Blood pressure = SVR × CO
HEMODYNAMIC PHYSIOLOGY
10. Physical Examination
Level of consciousness, activity, or agitation
State of hydration
Peripheral edema
Respiratory pattern
Peripheral perfusion/capillary refill time
Toe-to-core temperature gap
Heart rate and rhythm
Pulse characteristics
Urine output
Hepatomegaly
Jugular venous pressure
Pulmonary and cardiac auscultation
11. METHODS
NON INVASIVE INVASIVE
NIBP
ECG
Chest X ray
ECHO
Blood pressure monitoring-ABP
Central venous pressure monitoring
Pulmonary artery pressure
monitoring
Mixed venous oxygen monitoring
Cardiac output
15. CONTD..
Flow required across an occlusive cuff
Methods
Auscultatory
Oscillometric
Width of the inflatable bladder be 40% of the mid-
circumference of the limb, length should be twice the
width
16. Auscultatory NIBP
Pneumatic cuff inflated to occlude arterial blood flow
As cuff is deflated, audible frequencies (Korotkoff
sounds) are created
First sound = SBP
Last sound (or when muffled) = DBP
17. Auscultatory NIBP
Errors in measurement:
Long stethoscope tubing
Poor hearing in observer
Calibration errors of sphygmomanometer
Decreased blood flow in the extremity
Severe atherosclerosis (unable to occlude)
Inappropriate cuff size
Too rapid deflation
accuracy reduced : low cardiac output, significant
hypotension, hypoperfusion, vasoconstriction, dysrhythmias,
edema.
18. Oscillometric NIBP
Pneumatic cuff inflated to
occlude arterial blood flow
Cuff deflated, arterial
pressure pulsations detected
and analyzed
SBP = rapidly increasing
oscillations
MAP = maximal point of
oscillations
DBP = rapidly decreasing
oscillations
Dina map (device for
indirect noninvasive mean
arterial pressure)
19. Variations in BP by Age
Age Mean BP (mm Hg)
Newborn 73/55(30-60)
1 year 90/55
6 years 95/57(60-100)
10 years 102/62
14 years 120/80
Adult 120/80
Elderly (over 70 years) Diastolic pressure may increase
21. ELECTROCARDIOGRAM
Evaluation of heart rate and rhythm,
ischemia, and conduction defects
Trend monitor
Sources of errors:
Waveform artefact
Electrocautery (diathermy) is the
main source of electrical
interference
Muscle activity
Movement artefact
22.
23. INVASIVE MONITORING
INVASIVE BLOOD PRESSURE:
Continuous monitoring of systemic arterial blood
pressure,
Frequent blood sampling, and
Withdrawal of blood during exchange transfusions
24. Arterial Blood Pressure
Monitoring Components
Arterial cannula with a
heparinized saline column
and flushing device
Transducer
Amplifier
Oscilloscope.
25. Advantages
Providing continuous monitoring,
Providing access for blood sampling
Display of the waveform in addition to the BP value
True heart rate in the presence of dysrhythmias
Allows specific management strategies to be directed
by changes in systolic, diastolic, or pulse pressure,
rather than mean pressure alone.
27. Factors that increase the risk of arterial catheter
thrombosis:
Larger catheter-to-vessel ratio
Prolonged cannulation
Multiple cannulation attempts
Presence of peripheral vascular disease
Venous and arterial femoral Catheterization in single
extremity
Younger age
Thrombogenic conditions
28. Sources of error
Inaccurate transducer level.
Recordings should be made with the child in the supine
position and the transducer at the level of the mid-chest
or mid-axillary line. ( 7.5 mm Hg for each 10 cm change
in position)
Zeroing
Careful flushing of the catheter and pressure tubing to
remove blood and air bubbles and choosing the
shortest, stiffest, and largest catheter.
29. SVO2 60-75%
Stroke volume 50-100 mL
Stroke index 25-45 mL/M2
Cardiac output 4-8 L/min
Cardiac index 2.5-4.0 L/min/M2
MAP 60-100 mm Hg
CVP 2-6 mm Hg
PAP systolic 20-30 mm Hg
PAP diastolic 5-15 mm Hg
PAOP (wedge) 8-12 mm Hg
SVR 900-1300 dynes.sec.cm-5
30. Central Venous Pressure Monitoring
Indications:
assessment of right heart filling pressure
monitoring of large fluid shifts from the intravascular to
the extravascular space and vice versa
Infusion of vasoactive substances
infusion of hyperosmolar fluids and/or irritants
31. Central Venous Pressure Monitoring
Secure IV access in critically ill children who may
require large-volume fluid infusions or parenteral
nutrition
Monitoring cvp-indirect measurement of cardiac
preload
Provides access for blood sampling for measurement
of mixed venous saturation.
CVP- 0 – 6 mmHg
32.
33.
34. Information Obtained from CVP
Waveforms
Loss of A wave and irregular rhythm = suggests atrial
fibrillation or flutter
Cannon A waves = junctional rhythm, complete heart
block, ventricular arrhythmias, TS, RVH, PS, Pulm
HTN
35. Complications
Central line insertion Indwelling catheters
Arterial (carotid, subclavian, femoral)
puncture
Local hematoma
Air embolism
Catheter malposition (to neck tissue,
mediastinal, pericardial, or pleural
cavities)
Pneumothorax
Hemothorax
Brachial plexus injury
Dysrhythmias
Infection
Local hematoma
Extravasation
Vascular thrombosis
Embolus (clot or air)
Intracardiac thrombus
Superior vena cava syndrome
Chylothorax
Local nerve damage
36. PULMONARY ARTERY CATHETERS
Septic shock unresponsive to fluid resuscitation and
low-dose vasopressor support,
Refractory shock following severe burn injuries,
Children with CHD, multiple organ failure, and
respiratory failure requiring high mean airway
pressures
37.
38.
39. CAPABILITIES OF PAC
determination of CVP,
pulmonary artery pressure (PAP), and
pulmonary artery occlusion pressure (PAOP), also
referred to as pulmonary capillary wedge pressure (Pw)
40. PULMONARY ARTERY PRESSURE
MONITORING
Assess fluid status
CO
tissue oxygenation (Svo2),
oxygen delivery (Do2) and consumption (Vo2),
pulmonary vascular resistance (PVR) and systemic
vascular resistance (SVR)
42. Cardiac Output Monitoring
CO = HR x SV
3.5 – 5 L/min/m2
Preload, afterload, HR, contractility
determinant of systemic oxygen delivery
shock, multiple organ failure, unexplained
hypotension, severe cardiac disease, significant
cardiopulmonary interactions.
43. Measures of adequate o2 supply
Mixed venous o2 saturation
blood lactate
Tissue CO2 tonometry
NIRS (Near Infrared Spectroscopy)
44. BLOOD LACTATE
Tissue dysoxia in states of mitochondrial dysfunction associated
with sepsis, poisoning, and various inborn errors of metabolism
Accelerated anerobic glycolysis
Lactate-containing replacement fluids during high-volume
hemofiltration
Acute hyperventilation can elevate blood lactate levels, perhaps
secondary to increased splanchnic release of lactate during
hyperventilation
45. Tissue PCO2 Monitoring Using Tonometry
Designed to measure tissue hypoperfusion
Involves placement of a CO2-permeable balloon
adjacent to a mucosal surface
Tissue hypoperfusion- increased intracellular CO2
Gastric tonometry: inconsistent results
Sublingual tonometry, suggested during early phases
of resuscitation
46.
47. Near Infrared Spectroscopy
Monitoring device for patients with potential
hemodynamic instability or deficits in regional
(primarily cerebral) perfusion
Deoxy Hb absorbs light in the range of 760 nm or
lower, whereas both deoxy and oxy Hb absorb light at
~800 nm
48.
49. TAKE HOME MESSAGE
Multiple different methods of hemodynamic
monitoring
Keys to success
Know when to use which method
Technical skills for device placement
Know how to interpret the data
Remember the limitations of the technology