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  1.  Activated charcoal itself is a fine, black powder that is odorless, tasteless, and nontoxic.  It works by binding (adsorbing) chemicals, thus reducing their toxicity (poisonous nature), through the GI tract.  It helps prevent the poison from being absorbed from the stomach into the body.
  2.  It is most effective when given within one hour after toxin ingestion .  It is the most effective decontaminant.  Bind substances excreted in the bile, interrupting enterohepatic circulation. The benefits are capable  to decontaminate the gut without requiring invasive procedures,  its rapid administration and its proven safety in both adults and children.
  3.  Mnemonic: These People Drink Charcoal Quickly  Theophylline  Phenobarbital  Dapsone  Carbamazepine  Quinine Others:  OPC poisoning, Multi drug overdose.
  4.  Activated charcoal is given through mouth or nasogastric tube, in an activated charcoal drug dose of 10:1 or  Dose 1 - 2 gm/kg  1-12 yrs -25-50 gm  Older than 12 yrs- 25-100 gm  Sorbitol and magnesium citrate are the most commonly used cathartics. But they are no longer recommended in poisonings.
  5.  The substance that does not adsorbed by activated charcoal .  Mnemonic:CHARCOAL  C-Caustics and corrosives  H-Heavy metals  A-Alcohol and glycols  R-Rapidly absorbed substances  C-Cyanide,chlorine  O-Other insoluble drugs  A-Aliphatic hydrocarbons  L-Laxatives
  6. Others:  Absent Bowel sound  Signs of intestinal obstruction  Oesophageal or gastric perforation
  7.  Constipation  Diarrhoea  Vomiting Pulmonary aspiration is a dreaded complication that results in  pneumonitis  obstruction in the respiratory tract  barotrauma  acute lung injury  Even in intubated patients ,aspiration pneumonia have occurred with instillation of activated charcoal.
  8.  Ingestion of large doses. Purposes:  Prevent continued absorption of a drug that may still present in GI tract.  Increase serum clearance of a drug.  After an initial dose of 50–100 g to an adult, activated charcoal should be administered  at a rate of not less than 12.5 g/h or equivalent.  Lower doses (10–25 g) of activated charcoal may be employed in children less than 5 years of age as usually they have ingested smaller overdoses and their gut lumen capacity is smaller
  9.  The Universal Antidote is a mixture that contains activated charcoal, magnesium oxide, and tannic acid. All three components neutralize the actions of many poisons.