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PRESENTED BY;
MISS.MAHALAKSHMI.L
MSC NURSING 1ST YEAR
FACULTY OF NURSING
SEMINAR ON PULMONARY
TUBERCULOSIS
Tuberculosis (TB) is one of the most
prevalent infections of human beings and
contributes considerably to illness and
death around the world. It is spread by
inhaling tiny droplets of saliva from the
coughs or sneezes of an infected person.it
is a slowly
granulomatous
spreading,
bacterial
chronic,
infection,
characterized by gradual weight loss
11/22/2013Free template from www.brainybetty.com 2
the infectiousTuberculosis is
disease primarily affecting lung
parenchyma is most often caused by
mycobacterium tuberculosis.it may
spread to any part of the body
including meninges,kidney,bones
and lymphnodes.
11/22/2013 3
4Free template from www.brainybetty.com
 PULMONARYTUBERCULOSIS
 AVIAN TUBERCULOSIS(
MICROBACTERIUM AVIUM ;OF BIRDS)
 BOVINE
TUBERCULOSIS(MYCOBACTERIUM
BOVIS ;OF CATTLE)
 MILIARY TUBERCULOSIS /
DISSEMINATED TUBERCULOSIS
5Free template from www.brainybetty.com
With the increased incidence of AIDS,
TB has become more a problem in the
U.S., and the world.
It is currently estimated that 1/2 of the
6Free template from www.brainybetty.com
billion) isworld's
infected
population (3.1
with Mycobacterium
tuberculosis
killsGlobal Emergency Tuberculosis
5,000 people a day
2.3 million die each year
Mycobacterium tuberculosis
Droplet
nuclei(coughing,sneezing,laughi
ng)
Exposure to TB
7Free template from www.brainybetty.com
 CLOSE CONTACT WITH SOME ONE WHO HAVE
ACTIVE TB.
 IMMUNO COMPROMISED STATUS
(ELDERLY,CANCER)
 DRUG ABUSE ANDALCOHOLISM
 PEOPLE LACKING ADEQUATE HEALTH CARE
 PRE EXISTING MEDICAL CONDITIONS (DIABETES
MELLITUS,CHRONIC RENAL FAILURE)
 IMMIGRANTS FROM COUNTRIES WITH HIGHER
INCIDENCE OF TB.
 INSTITUTIONALISATION(LONG TERM CARE
FACILITIES)
8Free template from www.brainybetty.com
 LIVING IN SUBSTANDARD CONDITIONS
 OCCUPATION(HEALTH CARE WORKERS)
9Free template from www.brainybetty.com
 CONSTITUTIONAL SYMPTOMS
 Anorexia
 Low grade fever
 Night sweats
 Fatique
 Weight loss
10
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 PULMONARYSYMPTOMS
 Dyspnea
 Non resolving bronchopneumonia
 Chest tightness
 Non productive cough
 Mucopurulent sputum with hemoptpysis
 Chest pain
 EXTRA PULMONARYSYMPTOMS
 Pain
 Inflammation
12
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 HISTORYCOLLECTION
 PHYSICAL EXAMINATION
 Clubbing of the fingers or toes (in people with advanced disease)
 Swollen or tender lymph nodes in the neck or other areas
 Fluid around a lung (pleural effusion)
 Unusual breath sounds (crackles)
13
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 IF MILIARYTB;
 A physical exam mayshow:
 Swollen liver
 Swollen lymph nodes
 Swollen spleen
14
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Tests may include:
 Biopsy of the affected tissue (rare)
 Bronchoscopy
 Chest CT scan
 Chest x-ray
 Interferon-gamma release blood test such as the
QFT-Gold test to test for TB infection
 Sputum examination and cultures
 Thoracentesis
 Tuberculin skin test (also called a PPD test)
15
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 QFT-Gold test measures interferon-gamma in
the testee's blood after incubating the blood with
specific antigens from M. Tuberculosis proteins
16
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 0.1 ML OF PPD IS INJECTED FOREARM(SC)
 AFTER 48-72 HRS CHECK FOR INDURATION AT
THE SITE
 IF INDURATION IS EQUAL TO AND MORE THAN
10MM
 POSITIVE
17
Free template from www.brainybetty.com
 Bones. Spinal pain and joint destruction may result
from TB that infects your bones(TB spine or potss
spine)
 Brain(meningitis)
 Liver or kidneys
 Heart(cardiac tamponade)
 Pleural effusion
 Tb pneumonia
 Serious reactions to drug therapy(hepato
toxicity;hypersentivity)
19
Free template from www.brainybetty.com
 PULMONARY TB is treated primarily with
antituberculosis agents for 6 to 12 months.
 Pharmacological management
 First line antitubercular medications
 Streptomycin 15mg/kg
 Isoniazid or INH(Nydrazid) 5 mg/kg(300 mg max
perday)
 Rifampin 10 mg/kg
 Pyrazinamide 15 – 30 mg/kg
 Ethambutol(Myambutol) 15 -25 mg/kg daily for 8
weeks and continuing for up to 4 to 7 months
11/22/2013
20
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Second line medications
Capreomycin 12 -15 mg/kg
Ethionamide 15mg/kg
Paraaminosalycilate sodium 200 -
300 mg/kg
Cycloserine 15 mg/kg
Vitamin b(pyridoxine) usually
adminstered with INH
21
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Other drugs that may be useful, but are
not on the WHO list of SLDs:
Rifabutin
Macrolides:e.g.,clarithromycin (CLR)
Linezolid(LZD)
Thioacetazone(T)
Thioridazine
Arginine
22
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 DOTS (directly observed treatment, short-course), is the name given
to the World Health Organization-recommended tuberculosis control
strategy that combines five components:
23
1
.
Government commitment (including both political will at all levels, and
establishing a centralized and prioritized system of TB monitoring,
recording and training)
2
.
Case detection by sputum smear microscopy
3
.
Standardized treatment regimen directly observed by a healthcare worker
or community health worker for at least the first two months
4
.
A regular drugsupply
5
.
A standardized recording and reporting system that allows assessment of
treatment results
 DOT is especially critical for patients with drug-
resistant TB, HIV-infected patients, and those on
intermittent treatment regimens (i.e., 2 or 3 times
weekly).
24
Free template from www.brainybetty.com
Multiple-drug therapy to treat TB means
taking several different antitubercular
drugs at the same time.
27
Free template from www.brainybetty.com
The standard treatment
isoniazid, rifampin, ethambutol,
is to take
and
pyrazinamide for 2 months. Treatment is
then continued for at least 4months with
fewer medicines
Assessment
Obtain history of exposure to TB
Assess for symptoms of active disease
Auscultate lungs for crackles
During drug therapy assess for liver
function
28
Free template from www.brainybetty.com
 Ineffective breathing pattern related to pulmonary
infection and potential for long term scarring with
decreased lung capacity
 Interventions
 Administer and teach self administration of
medications ordered
 Encourage rest and avoidance of exertion
 Moniter breath sounds respiratory rates ,sputum
production and dyspnoea
 Provide supplymental oxygen as ordered
 Encourage increased fluid intake
 Instruct about best position to facilitate drainage
29
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 Risk for spreading infection related to nature
of disease and patients symptoms
 Be aware that TB is transmitted by respiratory
droplets
 Use high efficiency particulate masks for high risk
procedures including endoscopy
 Educate patient to control the spread of infection
by covering mouth and nose while coughing and
sneezing
 Isolation of patient
 Instruct about risk of drug resistance if drug
regimen is not strictly and continuosly followed
 Carefully moniter vital signs and observe for
temperature changes
30
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 Imbalanced nutrition less than body
requirement related to poor appetite ,fatique
and productive cough
 Explain the importance of eating nutritious diet to
promote healing and defense against infection
 Provide small frequent meals
 Moniter weight of the patient
 Administer vitamin supplyments as ordered
31
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 Non compliance related to lack of motivation
and lack of treatment
 Educate patient about etiology transmission and
effects of TB
 Review adverse effects of drug therapy
 Participate in observation of medicine
taking,weekly pill counts or programmes designed
to increase compliance with the treatment for TB
 Explain that TB is a communicable disease and
that taking medications is most effective way of
preventing transmission
 Instruct about medications schecule and side
effects
32
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 ISOLATION
 Ventilate the room
 Cover the mouth
 Wear mask
 Finish entire course of medication
 vaccinations
33
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35
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PULMONARY TUBERCULOSIS

  • 1. PRESENTED BY; MISS.MAHALAKSHMI.L MSC NURSING 1ST YEAR FACULTY OF NURSING SEMINAR ON PULMONARY TUBERCULOSIS
  • 2. Tuberculosis (TB) is one of the most prevalent infections of human beings and contributes considerably to illness and death around the world. It is spread by inhaling tiny droplets of saliva from the coughs or sneezes of an infected person.it is a slowly granulomatous spreading, bacterial chronic, infection, characterized by gradual weight loss 11/22/2013Free template from www.brainybetty.com 2
  • 3. the infectiousTuberculosis is disease primarily affecting lung parenchyma is most often caused by mycobacterium tuberculosis.it may spread to any part of the body including meninges,kidney,bones and lymphnodes. 11/22/2013 3
  • 4. 4Free template from www.brainybetty.com
  • 5.  PULMONARYTUBERCULOSIS  AVIAN TUBERCULOSIS( MICROBACTERIUM AVIUM ;OF BIRDS)  BOVINE TUBERCULOSIS(MYCOBACTERIUM BOVIS ;OF CATTLE)  MILIARY TUBERCULOSIS / DISSEMINATED TUBERCULOSIS 5Free template from www.brainybetty.com
  • 6. With the increased incidence of AIDS, TB has become more a problem in the U.S., and the world. It is currently estimated that 1/2 of the 6Free template from www.brainybetty.com billion) isworld's infected population (3.1 with Mycobacterium tuberculosis killsGlobal Emergency Tuberculosis 5,000 people a day 2.3 million die each year
  • 8.  CLOSE CONTACT WITH SOME ONE WHO HAVE ACTIVE TB.  IMMUNO COMPROMISED STATUS (ELDERLY,CANCER)  DRUG ABUSE ANDALCOHOLISM  PEOPLE LACKING ADEQUATE HEALTH CARE  PRE EXISTING MEDICAL CONDITIONS (DIABETES MELLITUS,CHRONIC RENAL FAILURE)  IMMIGRANTS FROM COUNTRIES WITH HIGHER INCIDENCE OF TB.  INSTITUTIONALISATION(LONG TERM CARE FACILITIES) 8Free template from www.brainybetty.com
  • 9.  LIVING IN SUBSTANDARD CONDITIONS  OCCUPATION(HEALTH CARE WORKERS) 9Free template from www.brainybetty.com
  • 10.  CONSTITUTIONAL SYMPTOMS  Anorexia  Low grade fever  Night sweats  Fatique  Weight loss 10 Free template from www.brainybetty.com
  • 11.
  • 12.  PULMONARYSYMPTOMS  Dyspnea  Non resolving bronchopneumonia  Chest tightness  Non productive cough  Mucopurulent sputum with hemoptpysis  Chest pain  EXTRA PULMONARYSYMPTOMS  Pain  Inflammation 12 Free template from www.brainybetty.com
  • 13.  HISTORYCOLLECTION  PHYSICAL EXAMINATION  Clubbing of the fingers or toes (in people with advanced disease)  Swollen or tender lymph nodes in the neck or other areas  Fluid around a lung (pleural effusion)  Unusual breath sounds (crackles) 13 Free template from www.brainybetty.com
  • 14.  IF MILIARYTB;  A physical exam mayshow:  Swollen liver  Swollen lymph nodes  Swollen spleen 14 Free template from www.brainybetty.com
  • 15. Tests may include:  Biopsy of the affected tissue (rare)  Bronchoscopy  Chest CT scan  Chest x-ray  Interferon-gamma release blood test such as the QFT-Gold test to test for TB infection  Sputum examination and cultures  Thoracentesis  Tuberculin skin test (also called a PPD test) 15 Free template from www.brainybetty.com
  • 16.  QFT-Gold test measures interferon-gamma in the testee's blood after incubating the blood with specific antigens from M. Tuberculosis proteins 16 Free template from www.brainybetty.com
  • 17.  0.1 ML OF PPD IS INJECTED FOREARM(SC)  AFTER 48-72 HRS CHECK FOR INDURATION AT THE SITE  IF INDURATION IS EQUAL TO AND MORE THAN 10MM  POSITIVE 17 Free template from www.brainybetty.com
  • 18.
  • 19.  Bones. Spinal pain and joint destruction may result from TB that infects your bones(TB spine or potss spine)  Brain(meningitis)  Liver or kidneys  Heart(cardiac tamponade)  Pleural effusion  Tb pneumonia  Serious reactions to drug therapy(hepato toxicity;hypersentivity) 19 Free template from www.brainybetty.com
  • 20.  PULMONARY TB is treated primarily with antituberculosis agents for 6 to 12 months.  Pharmacological management  First line antitubercular medications  Streptomycin 15mg/kg  Isoniazid or INH(Nydrazid) 5 mg/kg(300 mg max perday)  Rifampin 10 mg/kg  Pyrazinamide 15 – 30 mg/kg  Ethambutol(Myambutol) 15 -25 mg/kg daily for 8 weeks and continuing for up to 4 to 7 months 11/22/2013 20 Free template from www.brainybetty.com
  • 21. Second line medications Capreomycin 12 -15 mg/kg Ethionamide 15mg/kg Paraaminosalycilate sodium 200 - 300 mg/kg Cycloserine 15 mg/kg Vitamin b(pyridoxine) usually adminstered with INH 21 Free template from www.brainybetty.com
  • 22. Other drugs that may be useful, but are not on the WHO list of SLDs: Rifabutin Macrolides:e.g.,clarithromycin (CLR) Linezolid(LZD) Thioacetazone(T) Thioridazine Arginine 22 Free template from www.brainybetty.com
  • 23.  DOTS (directly observed treatment, short-course), is the name given to the World Health Organization-recommended tuberculosis control strategy that combines five components: 23 1 . Government commitment (including both political will at all levels, and establishing a centralized and prioritized system of TB monitoring, recording and training) 2 . Case detection by sputum smear microscopy 3 . Standardized treatment regimen directly observed by a healthcare worker or community health worker for at least the first two months 4 . A regular drugsupply 5 . A standardized recording and reporting system that allows assessment of treatment results
  • 24.  DOT is especially critical for patients with drug- resistant TB, HIV-infected patients, and those on intermittent treatment regimens (i.e., 2 or 3 times weekly). 24 Free template from www.brainybetty.com
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  • 26.
  • 27. Multiple-drug therapy to treat TB means taking several different antitubercular drugs at the same time. 27 Free template from www.brainybetty.com The standard treatment isoniazid, rifampin, ethambutol, is to take and pyrazinamide for 2 months. Treatment is then continued for at least 4months with fewer medicines
  • 28. Assessment Obtain history of exposure to TB Assess for symptoms of active disease Auscultate lungs for crackles During drug therapy assess for liver function 28 Free template from www.brainybetty.com
  • 29.  Ineffective breathing pattern related to pulmonary infection and potential for long term scarring with decreased lung capacity  Interventions  Administer and teach self administration of medications ordered  Encourage rest and avoidance of exertion  Moniter breath sounds respiratory rates ,sputum production and dyspnoea  Provide supplymental oxygen as ordered  Encourage increased fluid intake  Instruct about best position to facilitate drainage 29 Free template from www.brainybetty.com
  • 30.  Risk for spreading infection related to nature of disease and patients symptoms  Be aware that TB is transmitted by respiratory droplets  Use high efficiency particulate masks for high risk procedures including endoscopy  Educate patient to control the spread of infection by covering mouth and nose while coughing and sneezing  Isolation of patient  Instruct about risk of drug resistance if drug regimen is not strictly and continuosly followed  Carefully moniter vital signs and observe for temperature changes 30 Free template from www.brainybetty.com
  • 31.  Imbalanced nutrition less than body requirement related to poor appetite ,fatique and productive cough  Explain the importance of eating nutritious diet to promote healing and defense against infection  Provide small frequent meals  Moniter weight of the patient  Administer vitamin supplyments as ordered 31 Free template from www.brainybetty.com
  • 32.  Non compliance related to lack of motivation and lack of treatment  Educate patient about etiology transmission and effects of TB  Review adverse effects of drug therapy  Participate in observation of medicine taking,weekly pill counts or programmes designed to increase compliance with the treatment for TB  Explain that TB is a communicable disease and that taking medications is most effective way of preventing transmission  Instruct about medications schecule and side effects 32 Free template from www.brainybetty.com
  • 33.  ISOLATION  Ventilate the room  Cover the mouth  Wear mask  Finish entire course of medication  vaccinations 33 Free template from www.brainybetty.com
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  • 35. 35 Free template from www.brainybetty.com