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Lecture 10   ESS_2nd semester ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Blood  circulation systemic pulmonary the heart  arteries  veins capillaries
pulmonary circulation systemic circulation portal circulation =  2 capillary beds link up each other
The heart functions as a pump the right and the left half an atrium + a ventricle valves -  atrioventricular semilunar the  wall of the  heart  -  three layers : the  endocardium   ( tunica interna )   -  is in contact with blood the   myocardium   ( tunica media )  - intermediate solid layer of  cardiac muscle tissue the   epicardium   ( tunica  externa) - smooth external covering layer =  visceral layer of pericardium
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
distributing artery    conducting  artery
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Conducting artery (aorta)
Conducting artery (aorta)
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Distributing artery
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Veins vessels conducting blood to the heart f unction:   veins serve as a blood reservoir the wall of veins  shows  3-layered organization  but  is much thinner in proportion to the size of the lumen than is that of the arteries t he wall, although thin, is however very strong because the connective tissue components are greatly developed (elastic and muscular elements are inconspicuous) a fter death the wall of the  veins tends to collapse i n some body regions ,  in particular the lower limbs, the  veins over 2 mm  in a diameter are provided with  vein valves  that prevent the blood in flowing back from the heart v alves are usually arranged in pairs opposite to one another histologically,  they are  duplicatures of the tunica intima
an artery a  vein
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],continuous   capillaries have  all layers good  developed c apillaries of this type  occur  in  the  central  nerv ous system  (cortex  of the telen-cephalon, cerebellar cortex ),  in  all kinds of muscle tissue,  the connective tissue, and exocrine glands
[object Object],[object Object],[object Object],[object Object],[object Object]
 
f enestrated capillaries  occur  in organs  with  rapid interchange of substances between cells and blood , i.e.  intestinal villi, pancreas, choroid plexus, ciliary body Remember:  modified fenestrated capillaries  are contained in the   renal glomeruli t he fenestrae are larger (70 - 90 nm) and more numerous than in the fenestrated capillaries of other organs, no diaphragms are present in the fenestrae sinusoidal capillaries , or  sinusoids  ( discontinuous capillaries ) are characterized by a tortuous path greatly enlarged diameter (30 - 40   m) and  discontinuous basal lamina and absence of pericytes the endothelial cells are separated each other by numerous and large gaps that facilitate the transport of substances between blood and cells s inusoids  occur  mainly in the  liver ,   some   hematopoietic organs   ( such as the bone marrow ), some  endocrine glands  (adenohypophysis, islets of Langerhans)
conduct lymph to the bloodstream they begin in the organs as blind  lymphatic capillaries they are  usually  collapsed in histological sections capillaries  collect tissue  (interstitial)  fluid from  the organs . They are called lacteals in the intestine. small and medium-sized lymphatic vessels   (lymphatics) c ontain the lymph and have  valves  in their lumina   main ducts:  ductus thoracicus -  thoracic  duct;   right lympatic duct  -  truncus lymphaceus dx .   both  empty the lymph into the bloodstream at the junction of the left internal jugular and left subclavian veins (angulus venosus)  Lymph vessels
Lymphatic capillaries   very simple structure : their wall is composed of endothelial cells and fine reticular fibres of circular orientation the basal lamina is not developed Lymphatic vessels and ducts are thin walled tubes  their  wall s   resemble   the wall s  of veins   it  consists of 3 layers: an intima, a media and an adventitia

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Microscopic anatomy and embryology of the cardiovascular system

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  • 3. Blood circulation systemic pulmonary the heart arteries veins capillaries
  • 4. pulmonary circulation systemic circulation portal circulation = 2 capillary beds link up each other
  • 5. The heart functions as a pump the right and the left half an atrium + a ventricle valves - atrioventricular semilunar the wall of the heart - three layers : the endocardium ( tunica interna ) - is in contact with blood the myocardium ( tunica media ) - intermediate solid layer of cardiac muscle tissue the epicardium ( tunica externa) - smooth external covering layer = visceral layer of pericardium
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  • 11. distributing artery conducting artery
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  • 21. an artery a vein
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  • 29. f enestrated capillaries occur in organs with rapid interchange of substances between cells and blood , i.e. intestinal villi, pancreas, choroid plexus, ciliary body Remember: modified fenestrated capillaries are contained in the renal glomeruli t he fenestrae are larger (70 - 90 nm) and more numerous than in the fenestrated capillaries of other organs, no diaphragms are present in the fenestrae sinusoidal capillaries , or sinusoids ( discontinuous capillaries ) are characterized by a tortuous path greatly enlarged diameter (30 - 40  m) and discontinuous basal lamina and absence of pericytes the endothelial cells are separated each other by numerous and large gaps that facilitate the transport of substances between blood and cells s inusoids occur mainly in the liver , some hematopoietic organs ( such as the bone marrow ), some endocrine glands (adenohypophysis, islets of Langerhans)
  • 30. conduct lymph to the bloodstream they begin in the organs as blind lymphatic capillaries they are usually collapsed in histological sections capillaries collect tissue (interstitial) fluid from the organs . They are called lacteals in the intestine. small and medium-sized lymphatic vessels (lymphatics) c ontain the lymph and have valves in their lumina main ducts: ductus thoracicus - thoracic duct; right lympatic duct - truncus lymphaceus dx . both empty the lymph into the bloodstream at the junction of the left internal jugular and left subclavian veins (angulus venosus) Lymph vessels
  • 31. Lymphatic capillaries very simple structure : their wall is composed of endothelial cells and fine reticular fibres of circular orientation the basal lamina is not developed Lymphatic vessels and ducts are thin walled tubes their wall s resemble the wall s of veins it consists of 3 layers: an intima, a media and an adventitia