D3 hepatotoksisite 2012

HEPATOTOKSİSİTE Prof.Dr. M. Cemil SAVAŞ GÜTF Gastroenteroloji BD

KC ilaç metabolizmasında temel organ

İlaç metabolizması ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Faz 1: Mikrozomal Cyt P450 sistemi

İlaç Hepatotoksisite Patogenez

TRANSAMİNAZ DÜZEYLERİNİ ARTTIRAN İLAÇLAR ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Klinik ve patolojik bulgular ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

İlaçlara bağlı başka tip KC injurileri ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Hepatotoksisite mekanizmaları ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Tanı ,[object Object],[object Object],[object Object],[object Object],[object Object]

Alkol en önemli hepatotoksik ajan

Tedavi ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

D3 hepatotoksisite 2012

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